300 results on '"Jun-Hee Park"'
Search Results
252. The Conversion of a Device And a Control Message in The Universal Middleware Bridge
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Jun-Hee Park, Kyeong-Deok Moon, Dong-Hee Kim, Kyungshik Lim, and Chang-Eun Lee
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business.industry ,Computer science ,Control (management) ,Interoperability ,computer.software_genre ,Bridge (nautical) ,Embedded system ,Middleware ,Middleware (distributed applications) ,Message oriented middleware ,Message broker ,business ,computer ,Computer network - Abstract
This paper describes how the conversion of a device and a control message is accomplished in a UMB. The UMB solves interoperability problems caused by the heterogeneity of several types of home network middleware. To solve the problems, conversion of a device and messages among the middleware is indispensable. Devices can see and control other devices connected to different middlewares in the UMB framework by the mechanism of device and message conversion.
- Published
- 2007
253. Abstract 2028: RUNX3 knockdown inhibited oral cancer-induced bone destruction via reducing TGF-β-dependent responses
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Won Yoon Chung, Jun-Hee Park, and Kwang Kyun Park
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Cancer Research ,Gene knockdown ,Oncology ,Chemistry ,medicine ,Cancer research ,Cancer ,medicine.disease ,Transforming growth factor - Abstract
Oral cancer ranks among the top 10 commonly diagnosed cancers. It easily invades underlying jaw bones and causes severe psychological and physical problems. When oral cancer cells infiltrate into jaw bones, survival rate of the patient is significantly decreased. Therefore, attention has been focused on molecular diagnostics and targeted therapy for oral cancer-induced bone destruction. However, there remains a lack of reliable biomarkers that can distinguish between bone-invasive and non-invasive oral cancers despite the recent advances in the field. The Runt domain transcription factor, RUNX3, has been found to be a tumor suppressor in many cancers through promoting transforming growth factor-β (TGF-β)-induced growth inhibition. However, the role of RUNX3 in oral cancer remains controversial. Here, we investigated whether RUNX3 has a critical role in oral cancer-induced bone destruction. In mice inoculated with RUNX3 knockdown oral cancer cells, tumor growth and bone destruction were significantly reduced. In oral cancer cells, RUNX3 knockdown significantly reduced cell viability in TGF-β-stimulated cells compared to unstimulated cells. Cell cycle analysis revealed that RUNX3 knockdown induced G1-specific cell-cycle arrest in the cancer cells without TGF-β treatment but G2-specific cell-cycle arrest in response to TGF-β treatment. RUNX3 knockdown inhibited cell migration and invasion in the absence or presence of TGF-β by changing both basal and TGF-β-induced level of epithelial-to-mesenchymal transition-related proteins. Furthermore, RUNX3 knockdown reduced parathyroid hormone-like protein expression, a major osteolytic factor, in oral cancer cells with or without TGF-β. We confirmed that RUNX3 knockdown in cancer cells decreased receptor activator of nuclear factor-kappaB ligand/osteoprotegerin ratio in osteoblastic hFOB1.19 cells treated with cancer cell-derived conditioned media. In summary, RUNX3 promotes oral cancer-induced bone destruction by enhancing interactions between cancer cells and bone cells as well as promoting malignant behavior of cancer cells. Therefore, RUNX3 may be a useful biomarker and potential therapeutic target for bone invasion of oral cancer. Citation Format: Junhee Park, Won-Yoon Chung, Kwang-Kyun Park. RUNX3 knockdown inhibited oral cancer-induced bone destruction via reducing TGF-β-dependent responses. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2028. doi:10.1158/1538-7445.AM2015-2028
- Published
- 2015
254. A Secure Wireless LAN Access Technique for Home Network
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Jae-Hyun Kim, Jun-Hee Park, Ju-A Lee, and Kyung-Duk Moon
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IEEE 802.11u ,Inter-Access Point Protocol ,Virtual LAN ,Computer science ,Network security ,Access control ,Computer security ,computer.software_genre ,Wireless LAN controller ,law.invention ,Home automation ,law ,Wireless lan ,Message authentication code ,Replay attack ,IEEE 802.11s ,Password ,Authentication ,business.industry ,Service set ,Network allocation vector ,WLAN Authentication and Privacy Infrastructure ,Authentication protocol ,Network Access Control ,IEEE 802.11i-2004 ,IEEE 802.11e-2005 ,IEEE 802.1X ,Challenge–response authentication ,business ,computer ,Computer network ,IEEE 802.11r-2008 - Abstract
IEEE 802.11i standard supports a secure access control for wireless LAN and IEEE 802.1X standard includes various authentication method protocols. It is expected that next-generation wireless LAN security techniques will be based on IEEE 802.1X and IEEE 802.11i standards. However, at present users who are not familiar with a computer and an authentication details have difficulty to setup the network security based on IEEE 802.11i. Accordingly, this paper proposes authentication scenarios to minimize the process by users, a password method which is changed randomly and periodically, and authentication protocols. The proposed protocols provide convenience for nonprofessional computer users as well as secure home network environment against the unwanted attacks such as a brute force attack or a replay attack
- Published
- 2006
255. IEEE1394 to UPnP software bridge structure
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Donghee Kim, Y. Poltavets, and Jun-Hee Park
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Structure (mathematical logic) ,computer.internet_protocol ,business.industry ,Computer science ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,computer.software_genre ,Bridge (interpersonal) ,Internet protocol suite ,Software ,Middleware ,Universal Plug and Play ,Operating system ,business ,computer ,Computer network - Abstract
This work presents the UPnP - IEEE1394 software bridge structure for representing legacy IEEE1394 devices to the UPnP middleware. This bridge implementation provides a UPnP based control mechanism for IEEE1394 devices and data transferring from IEEE1394 bus to IP network with formal conversion.
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- 2005
256. The Effects of Tonsillectomy Education Using Smartphone Text Message for Mothers and Children Undergoing Tonsillectomy: A Randomized Controlled Trial.
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Ji Yeon Yang, Hanna Lee, Yongai Zhang, Ji Uhn Lee, Jun Hee Park, and Eun Kyoung Yun
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TONSILLECTOMY ,SMARTPHONES ,TEXT messages ,HEALTH education ,HEALTH of mothers - Abstract
Background: Tonsillectomy is themost common type of surgical procedure performed in preschool children. Due to short period of hospitalization, mothers are expected tomanage their children's care at home. However, they are rarely provided with sufficient information about postoperative management. This study aims to determine the effectiveness of providing caregivers with information on tonsillectomy care by smartphone textmessaging in increasing their mothers' knowledge, reducing the anxiety, and improving the sick-role behavior of pediatric tonsillectomy patients. Materials andMethods:Asample of61 pediatric patients and their mothers was recruited. Participants were randomly assigned into either the experimental group (n = 27) or the control group (n = 34). The control group was given information about the tonsillectomy by conventional textual and verbal means, whereas the experimental group received the same information in the form of 10 textmessages during the period from hospitalization to their first follow-up visits. Results: Results of mixed design, two-way analysis of variance indicated significant interaction effects between time points and groups for mothers' knowledge (F = 4.26, p = 0.043) and children's anxiety (F = 3.32; p = 0.037). Thus, the results do support the effectiveness of tonsillectomy education using smartphone text messaging in increasing mothers' knowledge and reducing children's anxiety. Conclusions: These results can be applied to preoperative and postoperative interventions for children not only for tonsillectomy but also for many other operations. The development of various educational programs using smartphone text messaging for postoperative patient management would also be valuable. [ABSTRACT FROM AUTHOR]
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- 2016
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257. Electrical crosstalk analysis for gigabit optical transceiver module
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Kwang-Seong Choi, Jong-Hyun Lee, Sungil Kim, Byung-Seok Choi, Jong-Tae Moon, Jong-Deok Kim, Ho-Gyeong Yun, Yong-Seong Eom, and Jun-Hee Park
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Crosstalk ,XFP transceiver ,business.industry ,Ground line ,Gigabit ,Computer science ,Optical receivers ,Electrical engineering ,Transceiver ,Signal lines ,business ,Telecommunications - Abstract
We propose the electrical crosstalk reduction method of the gigabit transceiver module for the FTTH (Fiber-To-The-Home) applications. For the electrical crosstalk reduction between LD and PD, we insert a dummy ground line nearby a signal lines.
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- 2004
258. Microrna-365 inhibits the proliferation of vascular smooth muscle cells by targeting cyclin d1
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Ki-Chul Hwang, Jiyun Lee, Chang Yeon Lee, Se-Yeon Lee, Minji Seung, Eunhyun Choi, Jun-Hee Park, Pil-Ki Min, Hyuck Moon Kwon, Hyang-Hee Seo, Onju Ham, Eunmi Choi, and Myung-Hyun Kim
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Cyclin D1 ,Vascular smooth muscle ,business.industry ,Chemistry ,microRNA ,Cancer research ,Medicine ,business ,Cardiology and Cardiovascular Medicine ,Cell biology - Published
- 2014
259. Spatial mode behavior of second harmonic generation in a ridge-type waveguide with a periodically poled MgO-doped lithium niobate crystal
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Han-Young Lee, Jeongho Ha, Tai-Young Kang, and Jun-Hee Park
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Materials science ,Temperature control ,Physics and Astronomy (miscellaneous) ,business.industry ,Doping ,General Engineering ,Mode (statistics) ,Physics::Optics ,General Physics and Astronomy ,Second-harmonic generation ,Grating ,law.invention ,Nonlinear system ,Optics ,law ,Harmonic ,Optoelectronics ,business ,Waveguide - Abstract
We report on spatial mode behavior of the second harmonic (SH) generated by nonlinear interaction in the a z-cut Mg-doped periodically poled LiNbO3 (MgO:PPLN) ridge-type waveguide. Specific SH modes were selectively generated by mode mixing of the fundamental harmonic (FH) waves. In addition, high-order SH modes TM10 and TM01 were simultaneously generated under similar phase-matching conditions in a quasi-phase matching (QPM) grating structure. The interfered mode profiles of high-order SH modes demonstrated specific mode distribution to have a diagonal angle and the Laguerre–Gaussian (LG) mode at a certain phase-matching condition obtained by temperature control.
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- 2014
260. Clinical Outcomes of Treatment for Intracranial Aneurysm in Elderly Patients
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Jun Hee Park, Yong Cheol Lim, and Young Im Kim
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education.field_of_study ,medicine.medical_specialty ,Endovascular coiling ,Subarachnoid hemorrhage ,Microsurgical clipping ,business.industry ,Mortality rate ,medicine.medical_treatment ,Population ,Intracranial aneurysm ,medicine.disease ,Surgery ,Elderly ,Aneurysm ,Hematoma ,Statistical significance ,Medicine ,Original Article ,cardiovascular diseases ,Neurosurgery ,business ,education ,Outcome - Abstract
Objective The aim of this study is to evaluate the clinical course of intracranial aneurysm in patients aged 65 years and older and the immediate outcome after its aggressive management. Materials and Methods We performed a retrospective analysis using the medical records of 159 elderly patients managed at our institute from September 2008 to December 2013. Obtained clinical information included age, sex, Hunt and Hess grade (HHG), aneurysm location, Fisher grade (FG) and the treatment modality. Concomitant clinical data aside from cerebrovascular condition (hypertension, diabetes, previous medication) were evaluated to determine risk factors that might affect the functional outcomes. Results A total of 108 patients (67.9%) presented with subarachnoid hemorrhage (SAH), and 51 (32.1%) with unruptured intracranial aneurysms (UIAs). Coiling was performed in 101 patients and 58 patients underwent clipping. In the SAH population, 62 patients (57.4%) showed favorable outcomes, with a mortality rate of 11.3% (n = 18). In the UIAs population, 50 (98%) patients achieved 'excellent' and one (2%) achieved 'good' outcome. Factors including high-grade HHG (p < 0.001), advanced age (p = 0.014), and the presence of intraventricular hematoma (IVH) (p = 0.017) were significant predictors of poor outcome. Conclusion SAH patients with high grade HHG and IVH are associated with poor outcome with statistical significance, all the more prominent the older the patient is. Therefore, the indication for aggressive therapy should be considered more carefully in these patients. However, as the outcomes for elderly patients with UIAs were excellent regardless of the treatment modality, aggressive treatment could always be considered in UIAs cases.
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- 2014
261. A Case of Giant Carcinosarcoma of the Parotid Gland
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Jun Hee Park, Shin Chul Jung, Nam Yong Do, and Byung Ha Kim
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Mixed tumor ,Lung ,Salivary gland ,business.industry ,Uterus ,Anatomy ,medicine.disease ,Submandibular gland ,Malignant mixed tumor ,Parotid gland ,medicine.anatomical_structure ,stomatognathic system ,Otorhinolaryngology ,Carcinosarcoma ,Medicine ,Surgery ,business - Abstract
Carcinosarcoma, or true malignant mixed tumor of the salivary gland, is a very rare malignant tumor comprised of both carcinomatous and sarcomatous elements and accounts for only 0.040.16% of all salivary gland tumors. Carcinosarcoma usually occurs in the parotid gland. Other locations including submandibular gland, minor salivary gland, uterus, bladder or lung have been reported. We report a rare case of carcinosarcoma of the parotid gland in an 85-year-old female. The tumor was large, about 19×17 cm in size, and was successfully excised. � Korean J Otorhinolaryngol-Head Neck Surg 2014;57:38-41 Key WordsZZCarcinosarcoma ㆍMalignant mixed tumor ㆍParotid gland.
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- 2014
262. Outcomes of Ultra-Early Decompressive Craniectomy after Severe Traumatic Brain Injury-Treatment Outcomes after Severe TBI
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Young Hwan Ahn, Jun Hee Park, Jin-Mo Cho, Se-Hyuk Kim, Yong Cheol Lim, Jung-Eon Park, Namkyu You, and Hyun-Yong Choi
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musculoskeletal diseases ,medicine.medical_specialty ,Clinical Article ,Traumatic brain injury ,Decompression ,business.industry ,Mortality rate ,medicine.medical_treatment ,Treatment outcome ,Glasgow Coma Scale ,Glasgow coma scale ,Decompressive craniectomy ,Brain injuries ,medicine.disease ,Surgery ,Anesthesia ,medicine ,In patient ,business ,Ultra early surgery ,Intracranial pressure - Abstract
Objective The beneficial effect of decompressive craniectomy in the treatment of severe traumatic brain injury (TBI) is controversial, but there is no debate that decompression should be performed before irreversible neurological deficit occurs. The aim of our study was to assess the value of ultra-early decompressive craniectomy in patients with severe TBI. Methods Total of 127 patients who underwent decompressive craniectomy from January 2007 to December 2013 was included in this study. Among them, 60 patients had underwent ultra-early (within 4 hours from injury) emergent operation for relief of increased intracranial pressure. Initial Glasgow coma scale, brain computed tomography (CT) scan features by Marshall CT classification, and time interval between injury and craniectomy were evaluated retrospectively. Clinical outcome was evaluated, using the modified Rankin score. Results The outcomes of ultra-early decompressive craniectomy group were not better than those in the comparison group (p=0.809). The overall mortality rate was 68.5% (87 patients). Six of all patients (4.7%) showed good outcomes, and 34 patients (26.8%) remained in a severely disabled or vegetative state. Forty of sixty patients (66.7%) had died, and two patients (3.3%) showed good outcomes at last follow-up. Conclusion Ultra-early decompressive craniectomy for intracranial hypertension did not improve patient outcome when compared with "early or late" decompressive craniectomy for managing severe TBI.
- Published
- 2014
263. Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature.
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Hun-Jae Oh, Nam-yong Do, Keun-Hong Kee, Jun-Hee Park, Oh, Hun-Jae, Do, Nam-yong, Kee, Keun-Hong, and Park, Jun-Hee
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PAROTID gland surgery ,LARYNGEAL tumors ,IMMUNOHISTOCHEMISTRY ,RADIOTHERAPY treatment planning - Abstract
Background: Epithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue.Case Presentation: We report a rare case of epithelial-myoepithelial carcinoma, which developed in the subglottic region. A 78-year-old Korean woman visited our hospital complaining of hoarseness, which had developed 1 month previously. Flexible laryngoscopy showed a round mass that blocked approximately 80 % of the tracheal diameter. Complete excision of the mass was carried out under general anesthesia, using a transoral approach. Epithelial-myoepithelial carcinoma was diagnosed following immunohistochemical analysis.Conclusions: We report a rare case of epithelial-myoepithelial carcinoma that occurred in the subglottic region. To the best of our knowledge, only one other case has been reported since this disease was first identified approximately 40 years ago. [ABSTRACT FROM AUTHOR]- Published
- 2016
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264. 1H-pyrrole-2,5-dione-based small molecule-induced generation of mesenchymal stem cell-derived functional endothelial cells that facilitate rapid endothelialization after vascular injury.
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Byeong-Wook Song, Il-Kwon Kim, Seahyoung Lee, Eunhyun Choi, Onju Ham, Se-Yeon Lee, Chang Yeon Lee, Jun-Hee Park, Jiyun Lee, Hyang-Hee Seo, Woochul Chang, Cheesoon Yoon, and Ki-Chul Hwang
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PYRROLES ,MESENCHYMAL stem cells ,TREATMENT of vascular diseases ,CD31 antigen ,CELLULAR therapy ,IMMUNOCYTOCHEMISTRY ,PRINCIPAL components analysis ,THERAPEUTICS - Abstract
Introduction: Despite the success of interventional processes such as drug-eluting stents, complete prevention of restenosis is still hindered by impaired or delayed endothelialization or both. Here, we report that 1H-pyrrole-2,5-dione-based small molecule-generated mesenchymal stem cell-derived functional endothelial cells (MDFECs) facilitated rapid transmural coverage of injured blood vessels. Methods: Small molecules that induced CD31 expression were screened by principal component analysis (PCA). Rat mesenchymal stem cells (MSCs) were treated with selected small molecules for up to 16 days, and the expression levels of CD90 and CD31 were examined by immunocytochemistry. In vitro functional assays of MDFECs, including tube formation assays and nitric oxide production assays, were performed. After MDFECs (intravenous, 3×10
6 cells per animal) were injected into balloon-injured rats, neointima formation was monitored for up to 21 days. The endothelial coverage of denuded blood vessels was evaluated by Evans Blue staining. The functionality of repaired blood vessels was evaluated by measuring vasorelaxation and hemodynamic changes. Additionally, derivatives of the selected small molecules were examined for their ability to induce endothelial markers. Results: PCA indicated that 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione effectively induced MDFECs. MDFECs inhibited the neointima formation of denuded blood vessels by facilitating more rapid endothelialization. Further examination indicated that derivatives with a 1H-pyrrole-2,5-dione moiety are important for initiating the endothelial cell differentiation of MSCs. Conclusions: Small molecules with 1H-pyrrole-2,5-dione as a core structure have great potential to improve the efficacy of MSC-based cell therapy for vascular diseases, such as atherosclerosis and restenosis. [ABSTRACT FROM AUTHOR]- Published
- 2015
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265. Survival of hypoxic human mesenchymal stem cells is enhanced by a positive feedback loop involving miR-210 and hypoxia-inducible factor 1
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Lee-So Maeng, Woochul Chang, Min Young Lee, Jun-Hee Park, Chee Soon Yoon, Ki-Chul Hwang, Chang Youn Lee, Moon-Seo Park, and Yong-An Chung
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MAPK/ERK pathway ,Cell Survival ,microRNA-210 ,Biology ,human mesenchymal stem cells ,Oxygen Consumption ,microRNA ,medicine ,Humans ,RNA, Small Interfering ,Protein kinase B ,Regulation of gene expression ,General Veterinary ,hypoxia ,Mesenchymal stem cell ,Mesenchymal Stem Cells ,Cobalt ,Hypoxia (medical) ,Hypoxia-Inducible Factor 1, alpha Subunit ,hypoxia inducible factor-1 ,Oxygen ,Transplantation ,MicroRNAs ,Gene Expression Regulation ,Immunology ,Cancer research ,Original Article ,medicine.symptom ,Stem cell - Abstract
The use of mesenchymal stem cells (MSCs) has emerged as a potential new treatment for myocardial infarction. However, the poor viability of MSCs after transplantation critically limits the efficacy of this new strategy. The expression of microRNA-210 (miR-210) is induced by hypoxia and is important for cell survival under hypoxic conditions. Hypoxia increases the levels of hypoxia inducible factor-1 (HIF-1) protein and miR-210 in human MSCs (hMSCs). miR-210 positively regulates HIF-1α activity. Furthermore, miR-210 expression is also induced by hypoxia through the regulation of HIF-1α. To investigate the effect of miR-210 on hMSC survival under hypoxic conditions, survival rates along with signaling related to cell survival were evaluated in hMSCs over-expressing miR-210 or ones that lacked HIF-1α expression. Elevated miR-210 expression increased survival rates along with Akt and ERK activity in hMSCs with hypoxia. These data demonstrated that a positive feedback loop involving miR-210 and HIF-1α was important for MSC survival under hypoxic conditions.
- Published
- 2013
266. Development Of A Heat Pipe Heat Dissipation Method For CPV Application.
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Seok-Hwan Moon, Kyu-Ho Lee, Soo-Hyun Hong, Sang-Choon Ko, Chi-Hoon Jun, Jae-Kyoung Mun, Ki-Sung Park, and Jun-Hee Park
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HEAT pipes ,ENERGY dissipation ,SOLAR concentrators ,PHOTOVOLTAIC power generation ,HEAT flux ,SUBSTRATES (Materials science) ,THERMAL properties - Abstract
Even when there is a sufficient heat dissipation area from the heat sink to the environment, if the heat flux in the chip package substrate cannot be transferred rapidly to the heat sink, a thermal problem may occur.
[1] In this study, a relatively thin CPV module compared to general models was considered. Because four solar chips are mounted on a center column in the CPV module, heat can accumulate rapidly. Therefore, a heat pipe with high thermal conductivity was considered as the heat dissipation method.[2] The heat pipe adopted in the present study is commercially available and has a circular type sintered wick in it. To apply the heat pipe to the CPV module with thin thickness and a central column with 4 solar cells, it should be pressed and bent. The thermal characteristics of the pressed and bent heat pipe was investigated experimentally. [ABSTRACT FROM AUTHOR]- Published
- 2014
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267. Gunshot Injury to the Anterior Arch of Atlas
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Jun Hee Park, Seok Won Kim, Hyeung Sun Kim, and Nam Yong Do
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Gunshot injury ,medicine.medical_specialty ,business.industry ,General Neuroscience ,Anterior arch ,GUNSHOT INJURY ,Poison control ,Case Report ,First cervical vertebra ,Cervical spine ,Surgery ,medicine.anatomical_structure ,Atlas (anatomy) ,medicine ,Atlas ,Neurology (clinical) ,Anatomic Location ,business ,Mechanical instability - Abstract
Penetrating injuries to the upper cervical spine resulting from gunshots are rare in South Korea due to restrictions of gun use. Moreover, gunshot wounds to the upper cervical spine without neurological deficits occur infrequently because of the anatomic location and surrounding essential structures. We present an uncommon case involving the surgical removal of a bullet located in the anterior arch of first cervical vertebra (C1) via a transoral approach without neurological complications or subsequent mechanical instability.
- Published
- 2012
268. Wide-Range Refractometric Sensor Using Differently Sensitive Y-Branched Waveguides
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Soon Woo Kwon, Sang-Shin Lee, Daewon Lee, Geun-Sik Son, Jun-Hee Park, Soon-Sup Park, Jae-Hwan Sim, Woo-Kyung Kim, and Han-Young Lee
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Spectrum analyzer ,Birefringence ,Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,General Engineering ,General Physics and Astronomy ,Rendering (computer graphics) ,law.invention ,Phase change ,Optics ,law ,business ,Waveguide - Abstract
A surface sensor rendering an extended detection range was proposed and demonstrated, taking advantage of a Y-branch structure. The sensing and reference waveguides, comprising the Y-branch structure, were overlaid with TiO2 films of different thicknesses; thus, they show unequal sensitivities. The phase change experienced by the two waveguides was in situ monitored through a birefringence analyzer. The interference number for the sensing waveguide was derived from the response of the reference waveguide. The implemented sensor was evaluated by varying the concentration of glucose solution, confirming that the proposed sensing scheme is useful for efficiently extending the detection range.
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- 2012
269. Simple route to ridge optical waveguide fabricated via controlled evaporative self-assembly
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Woo-Kyung Kim, Myunghwan Byun, Soon Woo Kwon, Dae Ho Yoon, Zhiqun Lin, Woo Seok Yang, and Jun-Hee Park
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Computer Science::Machine Learning ,SIMPLE (dark matter experiment) ,Materials science ,Ridge waveguides ,business.industry ,Physics::Optics ,General Chemistry ,Computer Science::Other ,Optics ,Materials Chemistry ,Ridge (meteorology) ,Optoelectronics ,Dry etching ,Self-assembly ,business ,Nonlinear Sciences::Pattern Formation and Solitons - Abstract
A simple route to intriguing patterns for optical waveguides was demonstrated by controlled evaporative self-assembly (CESA) of confined microfluid. Silica ridge waveguides were fabricated by applying wet and dry etching based on stripe patterns formed by CESA. The optical mode of the resulting waveguides was confirmed by exposing them to the 1064 nm transmission light.
- Published
- 2011
270. Continuous control of spatial mode rotation using second harmonic generation
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Ju Han Lee, Han-Young Lee, Myung-Gun Song, Kyung-Hwan Koo, Jun-Hee Park, Yena Kim, Woo-Jin Jeong, Yeung-Lak Lee, Hun-Hwa Kim, Woo-Kyung Kim, and Woo Seok Yang
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Optics ,Distribution (mathematics) ,Physics and Astronomy (miscellaneous) ,Ridge waveguides ,business.industry ,Chemistry ,Mode (statistics) ,Harmonic ,Second-harmonic generation ,Optical rotation ,business ,Rotation ,Interference (wave propagation) - Abstract
This paper reports a continuously rotating spatial mode contributed from the interference between two second harmonic (SH) high-order modes, TM10 and TM01, which were generated in z-cut MgO:LN ridge waveguides with a periodically poled structure. The TM10 and TM01 SH modes were generated from the mixed first harmonic (FH) modes, the phase-matching conditions of the two modes were controlled to be close and to overlap so that the two modes can interference each other. The experiment results showed the interference of the two modes created an odd mode distribution with a specific angle and the distribution was continuously rotating according to the operation temperature.
- Published
- 2010
271. Sequential bipolar radiofrequency lumbar sympathectomy in Raynaud's disease -A case report
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Keun-Man Shin, Seong-Jun Hong, Sang-Soo Kang, Jun Hee Park, and Sang-Moon Jung
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medicine.medical_specialty ,business.industry ,Pain medicine ,Case Report ,medicine.disease ,Surgery ,lcsh:RD78.3-87.3 ,Lesion ,Lumbar sympathectomy ,Anesthesiology and Pain Medicine ,Symptom relief ,lcsh:Anesthesiology ,Raynaud's disease ,Radiofrequency ,Anesthesiology ,Bipolar ,medicine ,Bipolar radiofrequency ,medicine.symptom ,business ,Short duration - Abstract
A 39-year-old female was suffering from cold-induced Raynaud's attacks in both hands and feet, with symptoms being most severe in her left foot. The patient did not respond to medical treatments and was referred to our department of pain medicine. We performed sequential bipolar radiofrequency lumbar sympathectomy to the patient, which offered a long duration of symptom relief. Sequential bipolar radiofrequency lesions could create continuous strip lesion, and thus, could achieve better results, while the potential risk of liquid neurolytic agents could be avoided.
- Published
- 2010
272. Granular Cell Tumor on Larynx
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Ji-Yun Choi, Sung Il Cho, Jun Hee Park, and Nam-Yong Do
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Larynx ,Pathology ,medicine.medical_specialty ,Granular cell tumor ,business.industry ,Stridor ,lcsh:R ,lcsh:Medicine ,Case Report ,Hyperplasia ,lcsh:Otorhinolaryngology ,medicine.disease ,lcsh:RF1-547 ,Dysphagia ,Asymptomatic ,Lesion ,Dissection ,medicine.anatomical_structure ,Otorhinolaryngology ,Medicine ,Surgery ,medicine.symptom ,business - Abstract
Granular cell tumors (GCTs) are uncommon neoplasm. They can originate in any part of the body. The most common sites of origin are in the head and neck, while the larynx is a relatively uncommon location. Patients affected with a laryngeal GCT typically present with persistent hoarseness, stridor, hemoptysis, dysphagia, and otalgia but, the tumor may be asymptomatic. Care must be taken to differentiate this lesion from others due to the presence of pseudo-epitheliomatous hyperplasia which overlies the GCT and may occasionally mimic squamous cell carcinoma. Therefore, a confirmative diagnosis should be made histopathologically and should be supported by immunohistochemical staining. These tumors are treated by complete surgical resection. Examining the complete removal of the tumor through securing a negative free margin is considered to be a consequential procedure. We experienced a 64-yr-old man with a laryngeal granular cell tumor involving the right true vocal cord. He was treated by surgical resection under a fine dissection laryngomicroscope. Here we present this case and a review of literature.
- Published
- 2010
273. Factors influencing Nurses' Organizational Citizenship Behavior
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Jun Hee Park, Eunkyung Yun, and Sang-Sook Han
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Adult ,Organizational citizenship behavior ,Attitude of Health Personnel ,Interprofessional Relations ,Construct validity ,Affective events theory ,Organizational commitment ,Nursing Staff, Hospital ,Organizational Culture ,Job Satisfaction ,Leadership ,Cross-Sectional Studies ,Transactional leadership ,Transformational leadership ,Cronbach's alpha ,Surveys and Questionnaires ,Humans ,Female ,Job satisfaction ,Power, Psychological ,Psychology ,Social psychology ,General Nursing - Abstract
Purpose: This study was conducted to identify the factors that influence nurses’ organizational citizenship behavior. Methods: A cross-sectional design was used, with a convenience sample of 547 nurses from four university hospitals in Seoul and Gyeonggi province. The data were collected through a questionnaire survey done from September 22 to October 10, 2008. The tools used for this study were scales on organizational citizenship behavior (14 items), self-leadership (14 items), empowerment (10 items), organizational commitment (7 items), job satisfaction (8 items) and transformational transactional leadership (14 items). Cronbach’s alpha and factor analysis were examined to test reliability and construct validity of the scale. The data collected were processed using SPSS Window 15.0 Program for actual numbers and percentages, differences in the dependent variable according to general characteristics, and means, standard deviations, correlation coefficients and multiple regression analysis. Results: The factors influencing nurses’ organizational citizenship behavior were identified as self-leadership (β=.247), empowerment (β=.233), job satisfaction (β=.209), organizational commitment (β= .158), and transactional leadership (β=.142). Five factors explained 42.0% of nurses’ organizational citizenship behavior. Conclusion: The results of this study can be used to develop further management strategies for enhancement of nurses’ organizational citizenship behavior.
- Published
- 2009
274. Unilateral phrenic nerve block guided by ultrasonography and nerve stimulator for the treatment of hiccup developed after tongue cancer operation - A case report
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Ji Su Jang, Seong Jun Hong, Keun Man Shin, Yeong Jun Yun, Sang Soo Kang, and Jun Hee Park
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medicine.medical_specialty ,business.industry ,Wound dehiscence ,Cancer ,medicine.disease ,Surgery ,Modified Radical Neck Dissection ,Phrenic nerve block ,medicine.anatomical_structure ,Tongue ,Anesthesia ,medicine ,Ultrasonography ,medicine.symptom ,business ,Surface anatomy ,Hiccups - Abstract
Hiccups are common benign and usually transient phenomenon that occur in nearly everyone. However, persistent or intractable hiccups can cause multiple problems including malnutrition, weight loss, fatigue, dehydration, insomnia, and wound dehiscence. We have experienced a case of postoperative persistent hiccup. The patient was formerly diagnosed tongue cancer and developed persistent hiccup after partial glossectomy with modified radical neck dissection and a radial forearm free-flap operation. He was unsuccessfully managed using pharmacologic methods, and then we tried phrenic nerve block guided by ultrasonography and a nerve stimulator because the surface anatomy of neck was deformed by the previous operation. Thirty minutes after the block, the hiccups disappeared.
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- 2009
275. let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3.
- Author
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Onju Ham, Se-Yeon Lee, Chang Youn Lee, Jun-Hee Park, Jiyun Lee, Hyang-Hee Seo, Min-Ji Cha, Eunhyun Choi, Soonhag Kim, and Ki-Chul Hwang
- Subjects
AUTOPHAGY ,APOPTOSIS ,MESENCHYMAL stem cells ,CELL transplantation ,ISCHEMIA ,REPERFUSION injury ,CASPASES - Abstract
Introduction: Mesenchymal stem cells (MSCs) have therapeutic potential for the repair of myocardial injury. The efficacy of MSC therapy for myocardial regeneration mainly depends on the survival of cells after transplantation into the infarcted heart. In the transplanted regions, reactive oxygen species (ROS) can cause cell death, and this process depends on caspase activation and autophagosome formation. Methods: A Software TargetScan was utilized to search for microRNAs (miRNAs) that target caspase-3 mRNA. Six candidate miRNAs including let-7b were selected and transfected into human MSCs in vitro. Expression of MEK-EKR signal pathways and autophagy-related genes were detected. Using ischemia/reperfusion model (I/R), the effect of MSCs enriched with let-7b was determined after transplantation into infarcted heart area. Miller catheter was used to evaluate cardiac function. Results: Here, we report that let-7b targets caspase-3 to regulate apoptosis and autophagy in MSCs exposed to ROS. Let-7b-transfected MSCs (let-7b-MSCs) showed high expression of survival-related proteins, including p-MEK, p-ERK and Bcl-2, leading to a decrease in Annexin V/PI- and TUNEL-positive cells under ROS-rich conditions. Moreover, autophagy-related genes, including Atg5, Atg7, Atg12 and beclin-1, were significantly downregulated in let-7b-MSCs. Using a rat model of acute myocardial infarction, we found that intramyocardial injection of let-7b-MSCs markedly enhanced left ventricular (LV) function and microvessel density, in accordance with a reduced infarct size and the expression of caspase-3. Conclusions: Taken together, these data indicate that let-7b may protect MSCs implanted into infarcted myocardium from apoptosis and autophagy by directly targeting caspase-3 signaling. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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276. Compact Blue Light Source by Single-Pass Second Harmonic Generation of DBR Tapered Laser Radiation.
- Author
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Jun-Hee Park, Jedrzejczyk, Daniel, Feise, David, Maabdorf, Andre, Paschke, Katrin, Tai-Young Kang, Jeong-Ho Ha, Geum Yoon Oh, Hae-Nam Jeon, Boobin Yim, and Han-Young Lee
- Abstract
We demonstrate a continuous-wave 460-nm compact visible laser module having a footprint of 75 mm × 25 mm × 25 mm. This blue light source is achieved through single-pass second harmonic generation with a distributed Bragg reflector tapered diode laser as a single-frequency pump source at ~920 nm in a periodically poled MgO-doped lithium niobate crystal with a planar waveguide. The compact blue laser module reached an optical output power of 286 mW with the highest optical conversion efficiency of 11.6% at room temperature. The power stability of the blue light from the laser module is measured at an output power of 268 mW with a variation of ±3.5% during a period of 1 h. [ABSTRACT FROM PUBLISHER]
- Published
- 2014
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277. Resource relation map based fault diagnosis and fault tolerance methods for home network environments.
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Jeu Young Kim, Ji Hyun Lee, Ji-Yeon Son, and Jun-Hee Park
- Published
- 2013
278. Hemoptysis after Left Subclavian Central Venous Catheterization during Anesthesia Induction for Open Heart Surgery - Two cases report
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Jun Yong Do, Keun Man Shin, Sung Jun Hong, Jun Hee Park, and Il Seok Kim
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medicine.medical_specialty ,Left subclavian ,Venous catheterization ,business.industry ,Hemodynamics ,Surgery ,Respiratory Medicine ,Anesthesiology and Pain Medicine ,Anesthesia ,Medicine ,Anesthesia induction ,Adverse effect ,Complication ,Airway ,business - Abstract
Central venous catheters allow a measurement of the hemodynamic variables that cannot be measured accurately by noninvasive means, and allow the delivery of medications and nutritional support that cannot be administered safely through peripheral venous catheters. Unfortunately, the use of central venous catheters is associated with adverse events that are hazardous to patients. Hemoptysis is a significant clinical presentation in respiratory medicine. Often a life threatening emergency, it mandates a prompt assessment and intervention. Fiberoptic bronchoscope is useful and essential for investigating the cause of hemoptysis as well as for managing airway hygiene. We report two cases of hemoptysis after left subclavian central venous catheterization along with the use of a fiberoptic bronchoscope for hemoptysis. (Korean J Anesthesiol 2007; 52: 91~4)
- Published
- 2007
279. Cervical Transforaminal Axis Measured by MRI and Its Relation to the Internal Jugular Vein, Internal Carotid Artery and Vertebral Artery
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Yeong Jun Yun, Jun Hee Park, Il Seok Kim, Keun Man Shin, Eun Seon Choi, Sang Soo Kang, and Seong Jun Hong
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Lamina ,business.industry ,Vertebral level ,Vertebral artery ,Spinous process ,Anova test ,Anatomy ,Anesthesiology and Pain Medicine ,medicine.anatomical_structure ,medicine.artery ,Epidural block ,medicine ,Internal carotid artery ,business ,Internal jugular vein - Abstract
Background: The safety of cervical transforaminal epidural block has been the subject of debate, therefore, this study was conducted to measure the angle of the cervical transforaminal axis and to investigate its relationship to the internal jugular vein, internal carotid artery and vertebral artery. Methods: One hundred cases of cervical MRI were reviewed. The angle between a line passing through the center of the vertebral body and spinous process and a line passing through the center of the lamina in C3-4, C4-5 and C5-6 was measured and designated as A-degree. A dditionally, we drew a line at the back of the vertebral artery that ran parallel to a line passing thr ough the center of the lamina, which was presented as A-line. We then examined the distribution of the area in which the internal jugular vein and the internal carotid artery were located. Results: The mean values of the A-degree in C3-4, C4-5 and C5-6 were 53.5 ± 4.3, 54.2 ± 4.6 and 54.3 ± 4.8, respectively. There were no statistically significant d ifferences among age groups or vertebral levels (ANOVA test, P > 0.05). The A-line was distributed primarily throughout zone 3, 4, and 5 in C3-4 and zone 5 in C4-5 and C5-6. Conclusions: The results of this study indicate that the mean values of A-degree were not statistically different among each age group and each vertebral level. However, the A-line may be located in the zone in which the internal jugular vein and the internal carotid artery lie and individual differences in the A-degree remain. (Korean J Pain 2007; 20: 143�� 147)
- Published
- 2007
280. General Middleware Bridge to Support Device Interoperability on Different Middlewares.
- Author
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Hark-Jin Lee, Young-sung Son, Jun-Hee Park, Kyeong-Deok Moon, and Jae-Cheol Ryou
- Published
- 2011
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281. A Scheme for Reliable Real-Time Messaging with Bounded Delays.
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Kim, K.H., Jing Qian, Zhen Zhang, Qian Zhou, Kyung-Deok Moon, Jun-Hee Park, Kwang-Roh Park, and Doo-Hyun Kim
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- 2010
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282. A Framework for Interoperability of Heterogeneous Devices in Ubiquitous Home.
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Hojin Park, Jun-Hee Park, and Nam Kim
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- 2010
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283. Realization of Fault-Tolerant Home Network Management Middleware with the TMO Structuring Approach and an Integration of Fault Detection and Reconfiguration Mechanisms.
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Kim, K.H., Qian Zhou, Jing Qian, Kyung-Deok Moon, Jun Hee Park, Young-Sung Son, Chang-Eun Lee, and Tai-Yeon Ku
- Published
- 2009
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284. Automating Configuration System and Protocol for Next-Generation Home Appliances.
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Eun-Seo Lee, Hark-Jin Lee, Kwangil Lee, and Jun-Hee Park
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HOUSEHOLD appliances industry ,INTERNET service providers ,MEDICAL care ,IEEE 802.11 (Standard) ,BODY composition ,BODY weight ,INFORMATION technology equipment - Abstract
Home appliance manufacturers have recently been trying to provide smart products capable of various Internet services. For example, one health care manufacturer provides a Wi-Fi-capable scale. Once users register their information with the manufacturer's server, their weight and body fat records are automatically uploaded to the server whenever they measure their weight. The users can then watch and check their weight log easily using a smart device, such as a smartphone or tablet. One of the biggest problems, however, is that the initial configuration of the appliances and the user registration process may be quite complicated to typical users who are unfamiliar with such IT devices. This paper proposes an autoconfiguration system structure and protocol for Internet-capable home appliances, which supports the initial configuration and remote maintenance service of the device with only little user effort. Manufacturers can develop their own information appliances and provide differentiated services using the proposed system and protocol. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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- View/download PDF
285. The Effect of Preoperative Pulmonary Arterial Pressure and Right Ventricular Function on the Changes in Right Ventricular Function after Mitral Valve Replacement
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Sang Hwa Kang, Jun Hee Park, Sang Boem Nam, Young Jun Oh, Yon Hee Shim, Young Lan Kwak, and Yong Woo Hong
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medicine.medical_specialty ,Ventricular function ,business.industry ,medicine.medical_treatment ,Mitral valve replacement ,Pulmonary arterial pressure ,Right ventricular ejection fraction ,Anesthesiology and Pain Medicine ,Surgery mitral valve replacement ,Internal medicine ,medicine ,Ventricular pressure ,Cardiology ,Systole ,business - Published
- 2001
286. Survival of hypoxic human mesenchymal stem cells is enhanced by a positive feedback loop involving miR-210 and hypoxia-inducible factor 1.
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Woochul Chang, Chang Youn Lee, Jun-Hee Park, Moon-Seo Park, Lee-So Maeng, Chee Soon Yoon, Min Young Lee, Ki-Chul Hwang, and Yong-An Chung
- Subjects
MESENCHYMAL stem cells ,MESENCHYME ,MYOCARDIAL infarction ,HYPOXEMIA ,MICRORNA - Abstract
The use of mesenchymal stem cells (MSCs) has emerged as a potential new treatment for myocardial infarction. However, the poor viability of MSCs after transplantation critically limits the efficacy of this new strategy. The expression of microRNA-210 (miR-210) is induced by hypoxia and is important for cell survival under hypoxic conditions. Hypoxia increases the levels of hypoxia inducible factor-1 (HIF-1) protein and miR-210 in human MSCs (hMSCs). miR-210 positively regulates HIF-1α activity. Furthermore, miR-210 expression is also induced by hypoxia through the regulation of HIF-1α. To investigate the effect of miR-210 on hMSC survival under hypoxic conditions, survival rates along with signaling related to cell survival were evaluated in hMSCs over-expressing miR-210 or ones that lacked HIF-la expression. Elevated miR-210 expression increased survival rates along with Akt and ERK activity in hMSCs with hypoxia. These data demonstrated that a positive feedback loop involving miR-210 and HIF-1α was important for MSC survival under hypoxic conditions. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
287. Cardiomyocytes from phorbol myristate acetate-activated mesenchymal stem cells restore electromechanical function in infarcted rat hearts.
- Author
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Heesang Song, Hye Jin Hwang, Woochul Chang, Byeong-Wook Song, Min-Ji Cha, II-Kwon Kim, Soyeon Lim, Eun Ju Choi, Onju Ham, Chang Youn Lee, Jun-Hee Park, Se-Yeon Lee, Eunmi Choi, Chungkeun Lee, Myoungho Lee, Moon-Hyoung Lee, Sung-Hou Kim, Yangsoo Jang, and Ki-Chul Hwang
- Subjects
MESENCHYMAL stem cells ,CARDIOMYOPATHIES ,HEART cells ,MUSCLE cells ,NORADRENALINE - Abstract
Despite the safety and feasibility of mesenchymal stem cell (MSC) therapy, an optimal cell type has not yet emerged in terms of electromechanical integration in infarcted myocardium. We found that poor to moderate survival benefits of MSC-implanted rats were caused by incomplete electromechanical integration induced by tissue heterogeneity between myocytes and engrafted MSCs in the infarcted myocardium. Here, we report the development of cardiogenic cells from rat MSCs activated by phorbol myristate acetate, a PKC activator, that exhibited high expressions of cardiac-specific markers and Ca
2+ homeostasis-related proteins and showed adrenergic receptor signaling by norepinephrine. Histological analysis showed high connexin 43 coupling, few inflammatory cells, and low fibrotic markers in myocardium implanted with these phorbol myristate acetate-activated MSCs. Infarct hearts implanted with these cells exhibited restoration of conduction velocity through ciacreased tissue heterogeneity and improved myocardial contractility. These findings have major implications for the development of better cell types for electromechanical integration of cell-based treatment for infarcted myocardium. [ABSTRACT FROM AUTHOR]- Published
- 2011
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288. Symptomatic Calcification of a Thyroid Lobe and Surrounding Tissue After Radioactive Iodine Treatment to Ablate the Lobe.
- Author
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Jin Hwa Kim, Jun Hee Park, Sang Yong Kim, and Hak Yeon Bae
- Subjects
- *
THYROID cancer , *CANCER diagnosis , *IODINE isotopes , *THYROIDECTOMY , *TOMOGRAPHY , *CALCIFICATION - Abstract
Background:Fine-needle aspiration diagnosis of follicular carcinoma presents a dilemma because malignancy is confirmed when vascular or capsular invasion is present. Completion thyroidectomy may be necessary when the diagnosis of follicular carcinoma is made following hemithyroidectomy. Ablation of the remaining lobe with radioactive iodine has been used as an alternative to completion thyroidectomy. Here we report an unusual apparent complication of this treatment.Patient Findings:A 51-year-old woman presented in September 24, 2009 with a stony, hard calcification of left thyroid gland. She complained of recent progressive hoarsening of her voice. Her medical history was positive for a subtotal thyroidectomy on September 6, 1993. Histologic analysis identified follicular carcinoma. Two months postoperatively, the remaining tissue was ablated with 131I (150 mCi) as an alternative to completion thyroidectomy. We performed computed tomography of the neck, which demonstrated 1.6 × 1.9 × 2.2 cm dense speculated calcification of the entire left residual thyroid gland. The calcification infiltrated the trachea wall. Completion thyroidectomy, including resection of the calcification, was performed. Histologic examination revealed dystrophic calcification.Conclusion:We report an unusual replacement of the thyroid remnant with calcification that developed over a period of 16 years following radioactive iodine lobe ablation as an alternative to completion thyroidectomy for thyroid follicular carcinoma. To our knowledge, this is the first such case in the English language literature. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
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289. A novel mutation Ala57Val of the ELA2 gene in a Korean boy with severe congenital neutropenia.
- Author
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Seung-Tae Lee, Hoi-Soo Yoon, Hee-Jin Kim, Jae-Hee Lee, Jun-Hee Park, Sun-Hee Kim, Jong-Jin Seo, and Ho Joom Im
- Subjects
LETTERS to the editor ,NEUTROPENIA - Abstract
A letter to the editor is presented on Ala57Val as a novel mutation underlying severe congenital neutropenia.
- Published
- 2009
- Full Text
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290. Towards Random Metasurface based Devices
- Author
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Boubacar Kante, Abdoulaye Ndao, Liyi Hsu, Matthieu Dupré, and Jun-Hee Park
- Subjects
0301 basic medicine ,Diffraction ,Fabrication ,Materials science ,business.industry ,Metamaterial ,Physics::Optics ,Transmission matrix ,Polarization (waves) ,03 medical and health sciences ,030104 developmental biology ,Full wave ,Optics ,Liquid crystal ,Electric field ,Nanorod ,Anisotropy ,business ,Plasmon - Abstract
Using full wave simulations and a transmission matrix approach, we design and then realize random metasurface lenses with anisotropic nanorods, and show that we can obtain a diffraction limited focal spot for all polarizations.
291. Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature
- Author
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Keun-Hong Kee, Jun Hee Park, Nam-Yong Do, and Hun-Jae Oh
- Subjects
Nasal cavity ,medicine.medical_specialty ,Pathology ,Case Report ,Epithelial-myoepithelial carcinoma ,Myoepithelioma ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Carcinoma ,Humans ,030212 general & internal medicine ,Subglottis ,Laryngeal Neoplasms ,Sinus (anatomy) ,Aged ,Medicine(all) ,business.industry ,General Medicine ,Laryngeal Neoplasm ,medicine.disease ,Parotid gland ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Female ,Radiology ,business ,Rare disease - Abstract
Background Epithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue. Case presentation We report a rare case of epithelial-myoepithelial carcinoma, which developed in the subglottic region. A 78-year-old Korean woman visited our hospital complaining of hoarseness, which had developed 1 month previously. Flexible laryngoscopy showed a round mass that blocked approximately 80 % of the tracheal diameter. Complete excision of the mass was carried out under general anesthesia, using a transoral approach. Epithelial-myoepithelial carcinoma was diagnosed following immunohistochemical analysis. Conclusions We report a rare case of epithelial-myoepithelial carcinoma that occurred in the subglottic region. To the best of our knowledge, only one other case has been reported since this disease was first identified approximately 40 years ago.
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292. Highly efficient green light generation in compact second-harmonic module with a periodically poled MgO-doped lithium niobate planar waveguide.
- Author
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Jun-Hee Park, Tai-young Kang, Hae-nam Jeon, Boobin Yim, and Han-Young Lee
- Published
- 2013
293. The Conversion of a Device And a Control Message in The Universal Middleware Bridge.
- Author
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Donghee Kim, Chang-Eun Lee, Jun Hee Park, KyeongDeok Moon, and Kyungshik Lim
- Published
- 2007
- Full Text
- View/download PDF
294. IEEE1394 to UPnP software bridge structure.
- Author
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Poltavets, Y., Jun-Hee Park, and Donghee Kim
- Published
- 2005
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295. Electrical crosstalk analysis for gigabit optical transceiver module.
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Sung-Il Kim, Yong-Seong Eom, Byung-Seok Choi, Kwang-Seong Choi, Ho-Gyeong Yun, Jong-Hyun Lee, Jun-Hee Park, Jong-Deok Kim, and Jong-Tae Moon
- Published
- 2003
- Full Text
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296. Spatial mode behavior of second harmonic generation in a ridge-type waveguide with a periodically poled MgO-doped lithium niobate crystal.
- Author
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Jun-Hee Park, Tai-Young Kang, Jeong-Ho Ha, and Han-Young Lee
- Abstract
We report on spatial mode behavior of the second harmonic (SH) generated by nonlinear interaction in the a z-cut Mg-doped periodically poled LiNbO
3 (MgO:PPLN) ridge-type waveguide. Specific SH modes were selectively generated by mode mixing of the fundamental harmonic (FH) waves. In addition, high-order SH modes TM10 and TM01 were simultaneously generated under similar phase-matching conditions in a quasi-phase matching (QPM) grating structure. The interfered mode profiles of high-order SH modes demonstrated specific mode distribution to have a diagonal angle and the Laguerre–Gaussian (LG) mode at a certain phase-matching condition obtained by temperature control. [ABSTRACT FROM AUTHOR]- Published
- 2014
- Full Text
- View/download PDF
297. Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study
- Author
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Hemant Kumar, Doo-Hoe Ha, Eun-Jong Lee, Jun Hee Park, Jeong Hyun Shim, Tae-Keun Ahn, Kyoung-Tae Kim, Alexander E. Ropper, Seil Sohn, Chung-Hun Kim, Devang Kashyap Thakor, Soo-Hong Lee, and In-Bo Han
- Subjects
Intervertebral disc degeneration ,Adipose-derived mesenchymal stem cells ,Nucleus pulposus ,Cell therapy ,Hyaluronic acid ,Medicine (General) ,R5-920 ,Biochemistry ,QD415-436 - Abstract
Abstract Background Adipose tissue-derived mesenchymal stem cells (AT-MSCs) offer potential as a therapeutic option for chronic discogenic low back pain (LBP) because of their immunomodulatory functions and capacity for cartilage differentiation. The goal of this study was to assess the safety and tolerability of a single intradiscal implantation of combined AT-MSCs and hyaluronic acid (HA) derivative in patients with chronic discogenic LBP. Methods We performed a single-arm phase I clinical trial with a 12-month follow-up and enrolled 10 eligible chronic LBP patients. Chronic LBP had lasted for more than 3 months with a minimum intensity of 4/10 on a visual analogue scale (VAS) and disability level ≥ 30% on the Oswestry Disability Index (ODI). The 10 patients underwent a single intradiscal injection of combined HA derivative and AT-MSCs at a dose of 2 × 107 cells/disc (n = 5) or 4 × 107 cells/disc (n = 5). Safety and treatment outcomes were evaluated by assessing VAS, ODI, Short Form-36 (SF-36), and imaging (lumbar spine X-ray imaging and MRI) at regular intervals over 1 year. Results No patients were lost at any point during the 1-year clinical study. We observed no procedure or stem cell-related adverse events or serious adverse events during the 1-year follow-up period. VAS, ODI, and SF-36 scores significantly improved in both groups receiving both low (cases 2, 4, and 5) and high (cases 7, 8, and 9) cell doses, and did not differ significantly between the two groups. Among six patients who achieved significant improvement in VAS, ODI, and SF-36, three patients (cases 4, 8, and 9) were determined to have increased water content based on an increased apparent diffusion coefficient on diffusion MRI. Conclusions Combined implantation of AT-MSCs and HA derivative in chronic discogenic LBP is safe and tolerable. However, the efficacy of combined AT-MSCs and HA should be investigated in a randomized controlled trial in a larger population. Trial registration ClinicalTrials.gov NCT02338271 . Registered 7 January 2015.
- Published
- 2017
- Full Text
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298. Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery
- Author
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Soon-Hyun Ahn, Hyun Jun Hong, Soon Young Kwon, Kee Hwan Kwon, Jong-Lyel Roh, Junsun Ryu, Jun Hee Park, Seung-Kuk Baek, Guk Haeng Lee, Sei Young Lee, Jin Choon Lee, Man Ki Chung, Young Hoon Joo, Yong Bae Ji, Jeong Hun Hah, Minsu Kwon, Young Min Park, Chang Myeon Song, Sung-Chan Shin, Chang Hwan Ryu, Doh Young Lee, Young Chan Lee, Jae Won Chang, Ha Min Jeong, Jae-Keun Cho, Wonjae Cha, Byung Joon Chun, Ik Joon Choi, Hyo Geun Choi, and Kang Dae Lee
- Subjects
Laryngeal Neoplasms ,Surgery ,Practice Guideline ,Glottis ,Supraglottis ,Medicine ,Otorhinolaryngology ,RF1-547 - Abstract
Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to develop clinical practice guidelines for the surgical treatment of laryngeal cancer. This Task Force conducted a systematic search of the EMBASE, MEDLINE, Cochrane Library, and KoreaMed databases to identify relevant articles, using search terms selected according to the key questions. Evidence-based recommendations were then created on the basis of these articles. An external expert review and Delphi questionnaire were applied to reach consensus regarding the recommendations. The resulting guidelines focus on the surgical treatment of laryngeal cancer with the assumption that surgery is the selected treatment modality after a multidisciplinary discussion in any context. These guidelines do not, therefore, address non-surgical treatment such as radiation therapy or chemotherapy. The committee developed 62 evidence-based recommendations in 32 categories intended to assist clinicians during management of patients with laryngeal cancer and patients with laryngeal cancer, and counselors and health policy-makers.
- Published
- 2017
- Full Text
- View/download PDF
299. Galectin-8 Expression in Laryngeal Squamous Cell Carcinoma
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Geun Woo Dong, Jun Kim, Jun Hee Park, Ji Yun Choi, Sung il Cho, and Sung Chul Lim
- Subjects
Galectin-8 ,Immunohistochemistry ,Larynx ,Squamous cell carcinoma ,Medicine ,Otorhinolaryngology ,RF1-547 - Abstract
ObjectivesDespite the ongoing development of treatment protocols for laryngeal squamous cell carcinoma (LSCC), the patients suffering with this malady have shown only a modestly improved outcome. This poor outcome has been attributed to the lack of therapy that's individualized to the tumor's biological properties. Various studies have showed that galectin-8 is widely expressed in tumor tissues as well as in normal tissues, and the level of the galectin-8 expression may correlate with the malignancy of human squamous cell carcinoma. The purpose of this study is to evaluate the expression of galectin-8 and to investigate its correlations with the primary stage, the nodal involvement, the clinical stage and the histologic grade of squamous cell carcinoma of the larynx.MethodsThe paraffin-embedded tissue specimens from 77 patients who were diagnosed as LSCC between 1993 and 2007 were immunohistochemically stained for galectin-8.ResultsImmunohistochemical analysis showed that a strong positive expression of galectin-8 was correlated with the T-stages, the nodal stages and the clinical stages. However, the histopathologic grades were not correlated with the galectin-8 expression in LSCC.ConclusionThe expression of galectin-8 protein can be used as a prognostic factor for patients with LSCC.
- Published
- 2009
- Full Text
- View/download PDF
300. MUSHROOMS AND CARDIOVASCULAR DISEASE.
- Author
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Eunmi Choi, Onju Ham, Se-Yeon Lee, Byeong-Wook Song, Min-Ji Cha, Chang Youn Lee, Jun-Hee Park, Jiyun Lee, Heesang Song, and Ki-Chul Hwang
- Subjects
- *
MUSHROOMS , *CARDIOVASCULAR diseases , *CHOLESTEROL , *LIPOPROTEINS , *ATHEROSCLEROSIS - Abstract
Many edible mushrooms have been used by ancient cultures to increase human longevity, as well as for good foods, while being devoid of undesirable side effects. Presently, mushrooms are appreciated and consumed primarily for their nutritional properties; however they are also increasingly used in medicine. Therefore, the food industry is especially interested in cultivated and wild mushrooms. The nutritional value of mushrooms is attributed to high levels of protein, fiber, carbohydrates, vitamins, and minerals and low fat levels. As cardiovascular disease is a major cause of morbidity and mortality in our society, mushrooms are currently investigated for their therapeutic properties. In in vitro and in vivo investigations, mushrooms were shown to reduce risk factors of cardiovascular disease such as high total cholesterol and low-density lipoprotein (LDL) cholesterol, low high-density lipoprotein (HDL) cholesterol, high blood pressure, atherosclerosis, and oxidative and inflammatory damage. In this review, we summarize the current understanding of mushroom effects on cardiovascular disease, and discuss the therapeutic applications of mushrooms for heart disease. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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