254 results on '"Marcello Lanari"'
Search Results
252. Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020
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Garazzino, S., Montagnani, C., Dona, D., Meini, A., Felici, E., Vergine, G., Bernardi, S., Giacchero, R., Vecchio, A. L., Marchisio, P., Nicolini, G., Pierantoni, L., Rabbone, I., Banderali, G., Denina, M., Venturini, E., Krzysztofiak, A., Badolato, R., Bianchini, S., Galli, L., Villani, A., Castelli-Gattinara, G., Salvini, F., Abbagnato, L., Castagnola, E., Dodi, I., Ghitti, C., Lippi, P., Agostiniani, R., Cherubini, S., Valentini, P., Gianino, P., Vaccaro, A., Manzoni, P., Verna, P., Comberiati, P., Di Filippo, P., Gallia, P., Battezzati, G., Fiore, L., Dalmazzo, C., Tappi, E., Lazzerini, M., Tovo, P. -A., Scolfaro, C., Pruccoli, G., Ramenghi, U., Giaquinto, C., da Dalt, L., Tornese, G., Berlese, P., Plebani, A., Manno, E. C., Santilli, V., Lancella, L., Cursi, L., Campana, A., Bozzola, E., Bosis, S., Lanari, M., Pecoraro, C., Del Barba, P., Nicastro, E., Esposito, S., Zuccotti, G. V., Corsello, G., Cardinale, F., Tocco, A. M., Ballardini, G., Agostoni, C., Chiappini, E., Indolfi, G., Anna, B., Cazzato, S., Zavarise, G., Pignata, C., Marchetti, F., Garazzino S., Montagnani C., Dona D., Meini A., Felici E., Vergine G., Bernardi S., Giacchero R., Vecchio A.L., Marchisio P., Nicolini G., Pierantoni L., Rabbone I., Banderali G., Denina M., Venturini E., Krzysztofiak A., Badolato R., Bianchini S., Galli L., Villani A., Castelli-Gattinara G., Salvini F., Abbagnato L., Castagnola E., Dodi I., Ghitti C., Lippi P., Agostiniani R., Cherubini S., Valentini P., Gianino P., Vaccaro A., Manzoni P., Verna P., Comberiati P., Di Filippo P., Gallia P., Battezzati G., Fiore L., Dalmazzo C., Tappi E., Lazzerini M., Tovo P.-A., Scolfaro C., Pruccoli G., Ramenghi U., Giaquinto C., da Dalt L., Tornese G., Berlese P., Plebani A., Manno E.C., Santilli V., Lancella L., Cursi L., Campana A., Bozzola E., Bosis S., Lanari M., Pecoraro C., Del Barba P., Nicastro E., Esposito S., Zuccotti G.V., Corsello G., Cardinale F., Tocco A.M., Ballardini G., Agostoni C., Chiappini E., Indolfi G., Anna B., Cazzato S., Zavarise G., Pignata C., Marchetti F., Garazzino, S., Montagnani, C., Dona, D., Meini, A., Felici, E., Vergine, G., Bernardi, S., Giacchero, R., Vecchio, A. L., Marchisio, P., Nicolini, G., Pierantoni, L., Rabbone, I., Banderali, G., Denina, M., Venturini, E., Krzysztofiak, A., Badolato, R., Bianchini, S., Galli, L., Villani, A., Castelli-Gattinara, G, Tornese, G, Filippo Salvini, Laura Abbagnato, Elio Castagnola, Icilio Dodi, Cesare Ghitti, Paola Lippi, Rino Agostiniani, Simonetta Cherubini, Piero Valentini, Paola Gianino, Angelina Vaccaro, Paolo Manzoni, Paola Verna, Pasquale Comberiati, Paola Di Filippo, Paola Gallia, Gianna Battezzati, Ludovica Fiore, Cristina Dalmazzo, Eleonora Tappi, Marta Lazzerini, PierAngelo Tovo, Carlo Scolfaro, Giulia Pruccoli, Ugo Ramenghi, Carlo Giaquinto, Liviana Da Dalt, Gianluca Tornese, Paola Berlese, Alessandro Plebani, Emma Concetta Manno, Veronica Santilli, Laura Lancella, Laura Cursi, Andrea Campana, Elena Bozzola, Samantha Bosis, Marcello Lanari, Carmine Pecoraro, Paolo Del Barba, Emanuele Nicastro, Silvia Garazzino, Carlotta Montagnani, Daniele Donà, Antonella Meini, Enrico Felici, Gianluca Vergine, Stefania Bernardi, Roberta Giacchero, Andrea Lo Vecchio, Paola Marchisio, Giangiacomo Nicolini, Luca Pierantoni, Ivana Rabbone, Giuseppe Banderali, Marco Denina, Elisabetta Venturini, Andrzej Krzysztofiak , Raffaele Badolato, Sonia Bianchini, Luisa Galli, Alberto Villani , Guido Castelli-Gattinara, Susanna Esposito, Gian Vincenzo Zuccotti, Giovanni Corsello, Fabio Cardinale, Anna Maria Tocco, Giuseppina Ballardini, Carlo Agostoni, Elena Chiappini, Giuseppe Indolfi, Bussolini Anna, Salvatore Cazzato, Giorgio Zavarise, Claudio Pignata, Federico Marchetti, Lo Vecchio, A., and Castelli-Gattinara, G.
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Male ,Pediatrics ,Epidemiology ,Protease Inhibitor ,Comorbidity ,medicine.disease_cause ,Clinical Laboratory Technique ,Severe Acute Respiratory Syndrome ,Disease Outbreaks ,Feces ,0302 clinical medicine ,Settore MED/38 - Pediatria Generale E Specialistica ,COVID-19 Testing ,Retrospective Studie ,Pandemic ,030212 general & internal medicine ,Viral ,Child ,Coronavirus ,Pediatric ,Disease Outbreak ,Coinfection ,Hospitals, Pediatric ,Settore MED/38 ,Hospitals ,Diarrhea ,Treatment Outcome ,SARS-CoV-2 infection ,children ,covid-19 ,hydroxychloroquine ,pneumonia ,Adolescent ,Antiviral Agents ,Betacoronavirus ,COVID-19 ,Child, Preschool ,Chronic Disease ,Clinical Laboratory Techniques ,Coronavirus Infections ,Female ,Fever ,Humans ,Immunocompromised Host ,Infant ,Infant, Newborn ,Italy ,Noninvasive Ventilation ,Pandemics ,Pneumonia, Viral ,Protease Inhibitors ,Retrospective Studies ,SARS-CoV-2 ,medicine.symptom ,Rapid Communication ,Human ,medicine.medical_specialty ,Coronaviru ,03 medical and health sciences ,030225 pediatrics ,Virology ,Intensive care ,medicine ,Preschool ,Antiviral Agent ,Betacoronaviru ,business.industry ,Coronavirus Infection ,Public Health, Environmental and Occupational Health ,Retrospective cohort study ,medicine.disease ,Newborn ,Pneumonia ,Fece ,business - Abstract
Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.
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- 2020
253. Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
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Chryssoula Tzialla, Arianna Dondi, Edoardo Carretto, Travan Laura, Giacomo Biasucci, Federico Marchetti, Giampaolo Garani, ICILIO DODI, Mauro Stronati, Licia Lugli, VITTORIO SAMBRI, Alberto Berardi, Jenny Bua, Alberto Berardi, Chryssoula Tzialla, Laura Travan, Jenny Bua, Daniele Santori, Milena Azzalli, Caterina Spada, Laura Lucaccioni, on behalf of the GBS Prevention Working Group of Emilia-Romagna [.., Marcello Lanari, Vittorio Sambri, and ]
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Male ,Intrapartum antibiotic prophylaxis ,Neonate ,0302 clinical medicine ,Pregnancy ,Surveys and Questionnaires ,Secondary Prevention ,Prevalence ,Late preterm ,Mass Screening ,030212 general & internal medicine ,Intrapartum antibiotic prophylaxi ,Pregnancy Complications, Infectious ,Survey ,Secondary prevention ,Group B streptococcu ,Neonatal sepsis ,lcsh:RJ1-570 ,Prenatal Care ,Anti-Bacterial Agents ,Primary Prevention ,Italy ,Female ,Neonatal sepsi ,Infection ,Adult ,medicine.medical_specialty ,Group B streptococcus ,Less invasive ,GBS ,Risk Assessment ,Streptococcus agalactiae ,Sepsis ,03 medical and health sciences ,Neonatal Screening ,Early onset sepsis ,Streptococcal Infections ,030225 pediatrics ,medicine ,Humans ,Newborn infant ,Neonatology ,Intensive care medicine ,business.industry ,Maternal and child health ,Research ,Prevention ,Infant, Newborn ,lcsh:Pediatrics ,Antibiotic Prophylaxis ,medicine.disease ,Health Surveys ,Risk factors ,Pediatrics, Perinatology and Child Health ,Commentary ,Risk factor ,business - Abstract
Background There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention. Methods Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility. Results All respondent obstetrical units used the culture-based screening approach to identify women who should receive intrapartum antibiotic prophylaxis, and more than half of the microbiological laboratories (58%) reported using specimen processing consistent with CDC guidelines. Most neonatal units (89 out of 107, 82%) reported using protocols for preventing GBS early-onset sepsis consistent with CDC guidelines. Conclusions The screening-based strategy is largely prevalent in Italy, and most protocols for preventing GBS early-onset sepsis are consistent with CDC guidelines. However, we found discrepancies in practices among centers that may reflect the lack of Italian guidelines issued by public health organizations. Electronic supplementary material The online version of this article (10.1186/s13052-017-0409-1) contains supplementary material, which is available to authorized users.
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- 2018
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254. The Management and Treatment of Acute Bronchiolitis in Infants
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Silvia, Vandini, Luca, Pierantoni, BIAGI, CARLOTTA, LANARI, MARCELLO, Silvia, Vandini, Carlotta, Biagi, Luca, Pierantoni, and Marcello, Lanari
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bronchiolitis, respiratory syncytial virus, infants, risk factors, treatment, high-flow nasal cannula therapy - Abstract
Acute bronchiolitis (AB) is the most common lower respiratory tract infection in young infants. It usually has viral etiology, being Respiratory Syncytial Virus (RSV) most frequently involved. The diagnosis is based on clinical history and physical examination, whereas diagnostic studies – including chest radiograph and blood tests – are generally not recommended in routine evaluation. To date, no etiologic antiviral drug is regularly used for the treatment of AB. Ribavirin is the only drug approved for RSV infection but its use is limited by the adverse side effects in patients and by the potential toxic risks it poses to health care providers. Other new antiviral agents are now object of ongoing studies. While these trials are still progressing, the current management of AB is essentially supportive, including oxygen therapy and hydration. Supplemental oxygen is the mainstay of treatment.in infants with respiratory distress and hypoxia; it can be administered with several techniques according to the severity of the respiratory impairment, starting from low-flow nasal cannula up to mechanical ventilation. The use of intravenous or nasogastric fluids supplementation is recommended to avoid dehydration in patients with AB and impaired feeding. Although several pharmacological treatments (nebulized hypertonic saline or bronchodilators, systemic corticosteroids or antibiotics) have been routinely administered in infants with AB over the past decades, at present their real efficacy is highly debated and their indication is controversial. Despite the existence of several clinical practice guidelines, many children with AB continue to undergo unnecessary tests and ineffective therapies worldwide. In the present chapter, we summarize the most recent literature about AB to provide an evidence-based approach to the management and treatment of this disease.
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- 2017
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