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257. Sprinkle Your Investment Portfolio with Water!

Author

Jin, Y., Roca, E., Li, B., Wong, V., Cheung, Adrian, Jin, Y., Roca, E., Li, B., Wong, V., and Cheung, Adrian

Abstract

This paper investigates the profitability of water-related investments and their diversification benefits in a portfolio context. Motivated by the need to understand whether or not water indices and water funds are desirable vehicles for investment, we analyse the performance of a major water index independently, as well as within portfolios. Our results indicate that the water asset class outperforms traditional asset classes, and has the capacity to produce diversification effects in portfolios primarily comprised of listed equity and bond assets. In addition, our study suggests that the diversification benefits of the water asset class are likely to be a result of its superior performance over the stock benchmark, rather than its low correlation with traditional asset classes. Our study provides a valuable contribution to the small, yet growing body of literature on water investments.

Published
2015

258. Crypto-currency bubbles: an application of the Phillips–Shi–Yu (2013) methodology on Mt. Gox bitcoin prices

Author

Cheung, Adrian, Roca, E., Su, J., Cheung, Adrian, Roca, E., and Su, J.

Abstract

The creation of bitcoin heralded the arrival of digital or crypto-currency and has been regarded as a phenomenon. Since its introduction, it has experienced a meteoric rise in price and rapid growth accompanied by huge volatility swings, and also attracted plenty of controversies which even involved law enforcement agencies. Hence, claims abound that bitcoin has been characterized by bubbles ready to burst any time (e.g. the recent collapse of bitcoin’s biggest exchange, Mt Gox). This has earned plenty of coverage in the media but surprisingly not in the academic literature. We therefore fill this knowledge gap. We conduct an econometric investigation of the existence of bubbles in the bitcoin market based on a recently developed technique that is robust in detecting bubbles – that of Phillips et al. (2013a). Over the period 2010–2014, we detected a number of short-lived bubbles; most importantly, we found three huge bubbles in the latter part of the period 2011–2013 lasting from 66 to 106 days, with the last and biggest one being the one that ‘broke the camel’s back’ – the demise of the Mt Gox exchange.

Published
2015

261. β-Defensin Genomic Copy Number Does Not Influence the Age of Onset in Huntington's Disease

Author

Vittori, A, Orth, M, Roos, Ra, Outeiro, Tf, Giorgini, F, Hollox, Ej, Bachoud-Levi, Ac, Bentivoglio, Ar, Biunno, I, Bonelli, Rm, Burgunder, Jm, Dunnett, Sb, Ferreira, Jj, Handley, Oj, Heiberg, A, Illmann, T, Landwehrmeyer, Gb, Levey, J, Martinez-Jaurrieta, Md, Nielsen, Je, Pro Koivisto, S, Piiiviirinta, M, Sebastian, Ar, Tabrizi, Sj, Vandenberghe, W, Verellen-Dumoulin, C, Zaremba, J, Uhrova, T, Wahlstrom, J, Barth, K, Correia-Guedes, L, Finisterra, Am, Bascuiiana Garde, M, Betz, S, Bos, R, Ecker, D, Held, C, Koppers, K, Laura, M, Descals, Am, Mestre, T, Monza, D, Townhill, J, Padieu, H, Paterski, L, Peppa, N, Rialland, A, Røren, N, Sasinkova, P, Trigo Cubillo, P, van Walsem, M, Witjes-Ane, Mn, Yudina, E, Zielonka, D, Zielonka, E, Zinzi, P, Herranhof, B, Hod, A, Kapfhammer, Hp, Koppitz, M, Magnet, M, Otti, D, Painold, A, Reisinge, K, Scheib, M, Hecht, K, Lilek, S, Muller, N, Schoggl, H, Ullah, J, Ribal, P, Klempff, J, Majerova, V, Roth, J, Hjermind, Le, Jakobsen, O, Vinthev-Jensen, T, Larsen, Iu, Stokholm, J, Hiivola, H, Martikainen, K, Tuuha, K, Santala, M, Milkereit, E, Kosinski, Cm, Probst, D, Reetz, K, Sass, C, Schiefer, J, Schlangen, C, Werner, Cj, Andrich, J, Ellrichmann, G, Hoffmann, R, Kaminski, B, Saft, C, Stamm, C, Lange, H, Lohle, M, Schmidt, S, Storch, A, Wolz, A, Wolz, M, Capetian, P, Lambeck, J, Zucker, B, Boelmans, K, Ganos, C, Hidding, U, Lewerenz, J, Miinchau, A, Schmalfeld, J, Stubbe, L, Zittel, S, Heinicke, W, Ribbat, M, Longinus, B, Miihlau, M, Peinemann, A, Stiidtler, M, Weindl, A, Winkelmann, J, Ziegler, C, Bechtel, N, Beckmann, H, Bohlen, S, Holzner, E, Reilmann, R, Rohm, S, Rumpf, S, Schepers, S, Dose, M, Leythaeuser, G, Marquard, R, Raab, T, Schrenk, C, Schuierer, M, Buck, A, Eschenbach, C, Landwehrmeyer, B, Lezius, F, Nepper, S, Niess, A, Schwenk, D, Siissmuth, S, Trautmann, S, Weydt, P, Cormio, C, de Tommaso, M, Sciruicchio, V, Serpino, C, Ghelli, E, Ginestroni, A, Bertini, E, Massaro, F, Mechi, C, Paganini, M, Piacentini, S, Pradella, S, Romoli, Am, Sorbi, S, Abbruzzese, G, Ferrandes, Mb, Di Maria, E, Ferrandes, G, Mandich, P, Marchese, R, Di Donato, S, Gellera, C, Genitrini, S, Mariotti, C, Nanetti, L, Soliveri, P, Tomasello, C, De Michele, G, Dimaio, L, Massarelli, M, Rinaldi, C, Roca, A, Rossi, F, Russo, Cv, Salvatore, E, Sorrentino, P, Tucci, T, De Nicola, A, Elifani, F, Petrollini, M, Martino, T, Lovo, F, Squitieri, F, Catalli, C, Di Giacopo, R, Fasano, A, Frontali, M, Guidubaldi, A, Ialongo, T, Jacopini, G, Loria, G, Piano, C, Piccininni, C, Quaranta, D, Romano, S, Soleti, F, Spadaro, M, van Hout MS, van Vugt JP, de Weert, A, Bolwijn, Jj, Neurologie, P, Dekker, M, Leenders, Kl, van Oostrom JC, Dumas, Em, Jurgens, Ck, van den Bogaard SJ, 't Hart EP, Kremer, B, Verstappen, Cc, van Walsem MR, Frich, J, Aaserud, O, Wehus, R, Bjørgo, K, Fannemel, M, Gørvell, P, Lorentzen, E, Koivisto, Sp, Retterstøl, L, Stokke, B, Bjørnevoll, I, Sando, Sb, Dziadkiewicz, A, Nowak, M, Robowski, P, Sitek, E, Slawek, J, Soltan, W, Szinwelski, M, Blaszczyk, M, Boczarska-Jedynak, M, Ciach-Wysocka, E, Gorzkowska, A, Jasinska-Myga, B, Opala, G, Klodowska, G, Stompel, D, Banaszkiewicz, K, Boewiriska, D, Bojakowska-Jaremek, K, Neurologii, A, Dec, M, Krawczyk, M, Rudziriska, M, Szczudlik, A, Szczygiel, E, Wasielewska, A, Wojcik, M, Bryl, A, Ciesielska, A, Klimberg, A, Marcinkowski, J, Samara, H, Sempolowicz, J, Janik, P, Kalbarczyk, A, Kwiecinski, H, Jamrozik, Z, Antczak, J, Jachinska, K, Krysa, W, Rakowicz, M, Richter, P, Rola, R, Ryglewicz, D, Sienkiewicz-Jarosz, H, Sulek, A, Witkowski, G, Zdzienicka, E, Zieora-Jakutowicz, K, Coelho, M, Mendes, T, Valadas, A, Andrade, C, Joao, Ps, Gago, M, Garrett, C, Guerra, Mr, Solis, P, Herrera, Cd, Garcia, Pm, Cubo, E, Mariscal, N, Sanchez, J, Barrero, Fj, Alonso-Frech, F, Perez, Mr, Fenollar, M, Garda, R, Rivera, Sv, Villanueva, C, Alegre, J, Bascuiiana, M, Ventura, Mf, Ribas, Gg, Moreno, Jl, Cubillo, Pt, Rufz, Pj, Frech, Fa, Dfaz, J, Guerrero, R, Artiga, Mj, Sanchez, V, Alcaraz, Lf, de Ia Arrixaca, V, Manzanares, S, Perea, Mf, Reinante, G, Arrixaca, Ia, Torres, Mm, Moreau, Lv, Barbera, Ma, Guia, Db, Hernanz, Lc, Catena, Jl, Sebastian, R, Ferrer, Pq, Carruesco, Gt, Bas, J, Busquets, N, Calopa, M, Buongiorno, Mt, Munoz, E, Elorza, Md, Lopez, Cd, Terol, Ds, Robert, Mf, Rufz, Bg, Casado, Ag, Martinez, Ih, Viladrich, Cm, Pons, R, Roca, E, Llesoy, Jr, Idiago, Jm, Vergara, Mr, Garcia, Ss, Riballo, Av, Hoglund, A, Palhagen, Se, Paucar, M, Sandstrom, B, Svenningsson, P, Reza-Soltani, Tw, Kaelin, A, Romero, I, Schupbach, M, Stebler, Y, Zaugg, Sw, Akhtar, S, Crooks, J, Curtis, A, de Souza, J, Rickards, H, Wright, J, Barker, Ra, Di Pietro, A, Fisher, K, Goodman, Ao, Hill, S, Kershaw, A, Mason, S, O'Keefe, D, Swain, R, Guzman, Nv, Busse, M, Butcher, C, Clenaghan, C, Dunnett, S, Fullam, R, Jones, L, Jones, U, Khalil, H, Minster, S, Owen, M, Hunt, S, Price, K, Rosser, A, Edwards, M, Ho, C, Mcgill, M, Pearson, P, Porteous, M, Brockie, P, Foster, J, Johns, N, Mckenzie, S, Rothery, J, Thomas, G, Yates, S, Burrows, L, Chu, C, Fletcher, A, Gallantrae, D, Harding, A, Hamer, S, Kraus, A, Laver, F, Longthorpe, M, Markova, I, Raman, A, Silva, M, Thomson, A, Wild, S, Yardumian, P, Hobson, E, Jamieson, S, Musgrave, H, Rowett, L, Toscano, J, Clayton, C, Dipple, H, Middleton, J, Patino, D, Andrews, T, Dougherty, A, Kavalier, F, Golding, C, Laing, H, Lashwood, A, Robertson, D, Ruddy, D, Whaite, A, Santhouse, A, Bruno, S, Doherty, K, Lahiri, N, Novak, M, Patel, A, Rosser, E, Tabrizi, S, Taylor, R, Warner, T, Wild, E, Arran, N, Bek, J, Callaghan, J, Craufurd, D, Howard, L, Hare, M, Huson, S, Johnson, L, Jones, M, Murphy, H, Oughton, E, Partington-Janes, L, Rogers, D, Snowden, J, Sollom, A, Stopford, C, Thompson, J, Trender-Gerhard, I., Vittori, Angelica, Orth, Michael, Roos, Raymund A C, Outeiro, Tiago F, Giorgini, F, Russo, Cinzia Valeria, Flaviano, and Hollox, Edward J

Subjects
Adult, Male, Age of Onset, DNA Copy Number Variations, Female, Genotype, Humans, Huntington Disease, Middle Aged, beta-Defensins, Disease, Biology, Genetic modifier, Article, Pathogenesis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Huntington's disease, medicine, Copy-number variation, Defensin, 030304 developmental biology, Genetics, 0303 health sciences, copy number variation, inflammation, Acquired immune system, medicine.disease, 3. Good health, Beta defensin, Neurology (clinical), Age of onset, 030217 neurology & neurosurgery
Abstract

Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the abnormal expansion of a CAG triplet repeat tract in the huntingtin gene. While the length of this CAG expansion is the major determinant of the age of onset (AO), other genetic factors have also been shown to play a modulatory role. Recent evidence suggests that neuroinflammations is a pivotal factor in the pathogenesis of HD, and that targeting this process may have important therapeutic ramifications. The human β-defensin 2 (hBD2)- encoded by DEFB4- is an antimicrobial peptide that exhibits inducible expression in astrocytes during inflammation and is an important regulator of innate and adaptive immune response. Therefore, DEFB4 may contribute to the neuroinflammatory processes observed in HD. Objective: In this study we tested the hypothesis that copy number variation (CNV) of the β-defensin region, including DEFB4, modifies the AO in HD. Methods and results: We genotyped β-defensin CNV in 490 HD individuals using the paralogue ratio test and found no association between β-defensin CNV and onset of HD. Conclusions: We conclude that it is unlikely that DEFB4 plays a role in HD pathogenesis.

Published
2013

264. Risk of overtreatment in patients with adrenal insufficiency: current and emerging aspects.

Author

Mazziotti, G., Formenti, A. M., Frara, S., Roca, E., Mortini, P., Berruti, A., and Giustina, A.

Subjects
ADRENAL insufficiency, OVERTREATMENT, THERAPEUTIC use of glucocorticoids, BIOMARKERS, THERAPEUTICS
Abstract

The effects of long-term replacement therapy of adrenal insufficiency (AI) are still a matter of controversy. In fact, the established glucocorticoid replacement regimens do not completely reproduce the endogenous hormonal production and the monitoring of AI treatment may be a challenge for the lack of reliable clinical and biochemical markers. Consequently, several AI patients are frequently exposed to relative glucocorticoid excess potentially leading to develop chronic complications, such as diabetes mellitus, dyslipidemia, hypertension and fragility fractures with consequent impaired QoL and increased mortality risk. This review deals with the pathophysiological and clinical aspects concerning the over-replacement therapy of primary and secondary AI. [ABSTRACT FROM AUTHOR]

Published
2017
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267. Evolution of the Western Mediterranean, In 'Regional Geology and Tectonics: Phanerozoic Passive Margins, Cratonic Basins and Global Tectonic Maps'

Author

Carminati E. (a, Doglioni C. (a), Gelabert B.(c), Panza G.F.(d), Raykova R.B., Roca E.(e), Sabat F.(e), and Scrocca D.(b)

Subjects
Western Mediterranean, rollback, subduction, S-wave velocity, backarc basin
Abstract

The western Mediterranean is the backarc basin of the Apennines-Maghrebides subduction, which retreated from west to east since Oligocene to present times. The slab transported into the mantle different segments of the oceanic and transitional continental lithosphere, previously stretched during the Mesozoic Tethys realm. The widest extension in the Mediterranean backarc basin occurred where the thinned, possibly oceanic lithosphere was present in the foreland, i.e., the present Ionian basin. The stretching in the Western Mediterranean backarc generated lithospheric boudins as the Corsica-Sardinia microplate. The stretching was asymmetric, being the roots of the boudins shifted eastward relative to the shallow section of the continental lithosphere. The "eastward" rejuvenation of the Western Mediterranean sub-basins, the eastward migration of the slab retreat, and the related magmatism and foredeep depocenters, they all support an eastward sub-lithospheric relative flow of the mantle. The slab retreat and the related backarc extension moved at a speed of few cm/year, being the fastest speed (2-4 cm/yr?) localized at the crest of the arc, presently positioned in the Ionian Sea. Contemporaneous to this process, the counter-clockwise rotation of Africa relative to Europe, generated a N-S convergence of few (2-5) mm/yr, responsible for the Pliocene to present compression acting along the northern offshore of Africa and Sicily. Being the Africa-Europe convergence much slower than the slab retreat, the origin of this latter process must be independent from the relative motion of the two major plates. This supports the coexistence of different geodynamic processes in the same area.

Published
2012
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268. Biometric and physiological parameters in wedge sole larvae (Dicologoglossa cuneata) depending on the culture density

Author

Herrera, M., Rodiles, A., Sánchez, B., Aguilar, J.M., and De la Roca, E.

Subjects
Estres, Acuicultura, peces, 251092 ACUICULTURA MARINA, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), cortisol, densidad, 310400 PRODUCCION ANIMAL, Cultivos Marinos y Recursos Pesqueros
Abstract

In this work we have studied the effect of culture density of wedge sole on growth and larval mortality, and analyzed, physiological indicators of stress parameters. Culture density significantly affect growth (larger alevins were those farmed at low densities). However, no affected survival. The cortisol content also varied with culture density, with values higher in fish at higher densities. However, glucose and lactate tested no change between treatments but increased significantly during the study. The results reflect that the values of cortisol in wedge sole larvae are superior to those described for other flatfish larvae and next to pelagic species. The highest concentration of this hormone to high density culture reflects a situation of stress in larvae that could respond to the lower growth rate in these culture conditions. This study is funded by the project Bonaqua (0433_BONAQUA_5_E POCTEP) financed by the EDRF (European Regional Development Fund). www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua En este trabajo se ha estudiado el efecto de la densidad de cultivo sobre el crecimiento y la mortalidad larvaria, analizándose, a su vez, parámetros fisiológicos indicadores de estrés. La densidad de cultivo afectó significativamente al crecimiento pero no a la supervivencia, siendo los alevines más grandes los cultivados a bajas densidades. El contenido en cortisol también varió con la densidad de cultivo, presentando valores más altos los ejemplares a altas densidades. Sin embargo, el lactato y la glucosa no experimentaron ningún cambio entre tratamientos, aunque aumentaron significativamente durante el estudio, para todas las densidades. Los resultados reflejan que los valores de cortisol en las larvas de acedía son superiores a los descritos para larvas de otros peces planos y próximos a los de especies pelágicas. La mayor concentración de esta hormona a alta densidad de cultivo refleja una situación de estrés en larvas que podría estar relacionada con la menor tasa de crecimiento. Este estudio está financiado por el proyecto Bonaqua (0433_BONAQUA_5_E POCTEP) financiado por el FEDER (Fondo Europeo de Desarrollo Regional). www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua

Published
2012

270. An integrated Eocene chronostratigraphy for the central sector of the SE margin of the Ebro Basin

Author

Beamud, Elisabet, Costa, E., Garcés, Miguel, Cabrera, Lluís, Roca, E., and Gómez-Paccard, Miriam

Subjects
Ebro Basin, Magnetostratigraphy, Eocene
Abstract

The Paleogene sedimentary record in the Pontils area (SE sector of the Ebro Basin) consists of a ~ 2000-m-thick sequence formed by the Mediona Fm, the Orpí Fm, the Pontils Gp, the Santa Maria Gp and the Sant Miquel de Montclar Conglomerates. The age of these materials is loosely constrained based on stratigraphic relationships with marine sediments and punctual mammal fossils and charophyte assemblages within the continental materials. In order to precise their chronology, a magnetostratigraphic section up to 1500-m-thick in the Pontils-Sant Miquel de Montclar area has been studied and correlated to the Global Polarity Time Scale. From this correlation the age of the Pontils Gp is established in Lutetian to middle Bartonian, the Collbàs Fm would be middle Bartonian and the overlying Sant Miquel Conglomerates would range from Bartonian to Priabonian. This new chronology has been integrated with recent magneto- and biostratigraphic studies in more northeasterly sectors of the SE margin of the Ebro Basin (Igualada and Montserrat areas). This new and continuous chronological framework is essential to unravel and quantify the rates of change in the Ebro Basin-Catalan Coastal Ranges system., This work is a contribution of the Geomodels Research Institute and the GGAC Group 2009 SGR 1198 of the Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya . It was funded by the project COFORSED CGL2010-17479

Published
2012

271. Discrepancies in reporting the CAG repeat lengths for Huntington's disease

Author

Quarrell, Ow, Handley, O, O'Donovan, K, Dumoulin, C, Ramos Arroyo, M, Biunno, I, Bauer, P, Kline, M, Landwehrmeyer, Gb, Barth, K, Correia Guedes, L, Maria Finisterra, A, Bascuñana Garde, M, Bos, R, Ecker, D, Held, C, Koppers, K, Laurà, M, Martínez Descals, A, Mclean, T, Mestre, T, Minster, S, Monza, D, Townhill, J, Orth, M, Padieu, H, Paterski, L, Peppa, N, Koivisto, Sp, Rialland, A, Røren, N, Šašinková, P, Cubillo, Pt, van Walsem MR, Witjes Ané MN, Yudina, E, Zielonka, D, Zielonka, E, Zinzi, P, Bachoud Lévi AC, Bentivoglio, Ar, Bonelli, R, Burgunder, Jm, Dunnett, Sb, Ferreira, Jj, Handley, Oj, Heiberg, A, Illmann, T, Levey, J, Nielsen, Je, Päivärinta, M, Roos, Ra, Rojo Sebastián, A, Tabrizi, Sj, Vandenberghe, W, Verellen Dumoulin, C, Zaremba, J, Uhrova, T, Wahlström, J, Bonelli, Rm, Herranhof, B, Holl, A, Kapfhammer, Hp, Koppitz, M, Magnet, M, Otti, D, Painold, A, Reisinger, K, Scheibl, M, Hecht, K, Lilek, S, Müller, N, Schöggl, H, Ullah, J, Brugger, F, Hepperger, C, Hotter, A, Mahlknecht, P, Nocker, M, Seppi, K, Wenning, G, Buratti, L, Hametner, Em, Holas, C, Hussl, A, Mair, K, Poewe, W, Wolf, E, Zangerl, A, Braunwarth, Em, Ribaï, P, Flamez, A, Morez, V, de Raedt, S, Boogaerts, A, van Reijen, D, Klempíř, J, Kucharík, M, Roth, J, Hjermind, Le, Jakobsen, O, Stokholm, J, Hasholt, L, Nørremølle, A, Sørensen, Sa, Hiivola, H, Martikainen, K, Tuuha, K, Peippo, M, Sipponen, M, Kosinski, Cm, Milkereit, E, Probst, D, Sass, C, Schiefer, J, Schlangen, C, Werner, Cj, Gelderblom, H, Priller, J, Prüss, H, Spruth, Ej, Andrich, J, Hoffmann, R, Kraus, Ph, Muth, S, Prehn, C, Saft, C, Salmen, S, Stamm, C, Steiner, T, Strassburger, K, Lange, H, Friedrich, A, Hunger, U, Löhle, M, Schmidt, S, Storch, A, Wolz, A, Wolz, M, Lambeck, J, Zucker, B, Boelmans, K, Ganos, C, Hidding, U, Lewerenz, J, Münchau, A, Schmalfeld, J, Stubbe, L, Zittel, S, Heinicke, W, Longinus, B, Uni, M, Bürk, K, Möller, Jc, Rissling, I, Peinemann, A, Städtler, M, Weindl, A, Bechtel, N, Beckmann, H, Bohlen, S, Hölzner, E, Reilmann, R, Rohm, S, Rumpf, S, Schepers, S, Beister, A, Dose, M, Hammer, K, Kieni, J, Leythaeuser, G, Marquard, R, Raab, T, Richter, S, Selimbegovic Turkovic, A, Schrenk, C, Schuierer, M, Wiedemann, A, Buck, A, Connemann, J, Eschenbach, C, Landwehrmeyer, B, Lezius, F, Nepper, S, Niess, A, Süssmuth, S, Trautmann, S, Weydt, P, Cormio, C, Difruscolo, O, Sciruicchio, V, Serpino, C, de Tommaso, M, Capellari, S, Cortelli, P, Gallassi, R, Poda, R, Rizzo, G, Scaglione, C, Bertini, E, Ghelli, E, Ginestroni, A, Massaro, F, Mechi, C, Paganini, M, Piacentini, S, Pradella, S, Romoli, Am, Sorbi, S, Abbruzzese, G, Bandettini di Poggio, M, Di Maria, E, Ferrandes, G, Mandich, P, Marchese, R, Albanese, A, Di Bella, D, Di Donato, S, Gellera, C, Genitrini, S, Mariotti, C, Nanetti, L, Paridi, D, Soliveri, P, Tomasello, C, De Michele, G, Di Maio, L, Rinaldi, C, Valeria Russo, C, Salvatore, E, Tucci, T, Cannella, M, Codella, V, De Gregorio, F, De Nicola, N, Martino, T, Simonelli, M, Squitieri, F, Catalli, C, Di Giacopo, R, Fasano, A, Frontali, M, Guidubaldi, A, Ialongo, T, Jacopini, G, Loria, G, Modoni, A, Piano, C, Piccininni, C, Quaranta, D, Romano, Silvia, Soleti, F, Spadaro, M, van Hout MS, van Vugt JP, Marit de Weert, A, Bolwijn, Jj, Dekker, M, Leenders, Kl, van Oostrom JC, Dumas, Em, Jurgens, Ck, van den Bogaard SJ, 't Hart EP, Kremer, B, Verstappen, Cc, Aaserud, O, Wehus, R, Bjørgo, K, Fannemel, M, Gørvell, P, Retterstøl, L, Overland, T, Stokke, B, Bjørnevoll, I, Sando, Sb, Sitek, E, Slawek, J, Soltan, W, Boczarska Jedynak, M, Jasinska Myga, B, Opala, G, Kodowska Duda, G, Banaszkiewicz, K, Szczudlik, A, Rudziñska, M, Wójcik, M, Dec, M, Krawczyk, M, Bryl, A, Ciesielska, A, Klimberg, A, Marcinkowski, J, Sempoowicz, J, Samara, H, Janik, P, Kalbarczyk, A, Kwiecinski, H, Jamrozik, Z, Antczak, J, Jachinska, K, Rakowicz, M, Richter, P, Ryglewicz, D, Witkowski, G, Zdzienicka, E, Suek, A, Krysa, W, Guedes, L, Coelho, M, Mendes, T, Valadas, A, Cavaco, S, Damásio, J, Magalhães, M, Gago, M, Garrett, C, Guerra, Mr, Barrero, F, Morales, B, Cubo, E, Mariscal, N, Sánchez, J, Alonso Frech, F, Rabasa Perez, M, Fenollar, M, García, R, Quiroga, Pp, Vázquez Rivera, S, Villanueva, C, Bascuñana, M, Fatás Ventura, M, García Ribas, G, García de Yébenes, J, López Sendón Moreno JL, García Ruíz PJ, José Saiz Artiga, M, Sánchez, V, Noguera Perea, F, Lorenza, F, Torres, Mm, Reinante, G, Vivancos Moreau, L, Barbera, Ma, Badenes Guia, D, Hernanz, Lc, Catena, Jl, Ferrer, Pq, Tome Carruesco, G, Bas, J, Busquets, N, Calopa, M, Dalmau Elorza, M, Díez, C, López, A, Durán, S, Terol, S, Floriach Robert, M, Garzón Ruíz, B, González Casado, A, Haro Martínez, I, Viladrich, Cm, Càrdenas R, Pons i., Roca, E, Llesoy, Jr, Ruiz Idiago JM, Ruíz Vergara, M, Soriano García, S, Villa Riballo, A, Gorospe, A, Legarda, I, Arques, Pn, Torres Rodríguez MJ, Vives, B, Gaston, I, Bosca, M, Burguera, Ja, Garcia, Ac, Pålhagen, Se, Paucar, M, Svenningsson, P, Walldén Reza Soltani, T, Höglund, A, Sandström, B, Høsterey Ugander, U, Fredlund, G, Constantinescu, R, Neleborn Lingefjärd, L, Tedroff, J, Esmaeilzadeh, M, Winnberg, E, Burgunder, Y, Stebler, Y, Kaelin, A, Romero, I, Schüpbach, M, Zaugg, Sw, Jack, R, Matheson, K, Miedzybrodzka, Z, Rae, D, Simpson, S, Summers, F, Ure, A, Crooks, J, Curtis, A, de Souza, J, Rickards, H, Wright, J, Barker, Ra, Di Pietro, A, Fisher, K, Goodman, A, Hill, S, Kershaw, A, Mason, S, Paterson, N, Raymond, L, Bisson, J, Busse, M, Clenaghan, C, Ellison Rose, L, Hunt, S, Price, K, Rosser, A, Edwards, M, Hughes, T, Mcgill, M, Pearson, P, Porteous, M, Smith, P, Zeman, A, Causley, A, Harrower, T, Howcroft, D, Lambord, N, Rankin, J, Brockie, P, Foster, J, Johns, N, Mckenzie, S, Rothery, J, Thomas, G, Yates, S, Miller, J, Ritchie, S, Burrows, L, Fletcher, A, Harding, A, Laver, F, Silva, M, Thomson, A, Barnes, K, Chu, C, Hobson, E, Jamieson, S, Markova, I, Thomson, J, Toscano, J, Wild, S, Yardumian, P, Bourne, C, Clayton, C, Dipple, H, Clapton, J, Grant, J, Gross, D, Hallam, C, Middleton, J, Murch, A, Patino, D, Andrews, T, Dougherty, A, Kavalier, F, Golding, C, Lashwood, A, Robertson, D, Ruddy, D, Whaite, A, Patton, M, Peterson, M, Rose, S, Bruno, S, Chu, E, Doherty, K, Henley, S, Lahiri, N, Novak, M, Patel, A, Read, J, Rosser, E, Say, M, Tabrizi, S, Taylor, R, Warner, T, Wild, E, Arran, N, Callaghan, J, Craufurd, D, Fullam, R, Howard, L, Huson, S, Oughton, E, Partington Jones, L, Snowden, J, Sollom, A, Stopford, C, Thompson, J, Trender Gerhad, I, Verstraelen, N, Westmoreland, L, Nemeth, Ah, Suida, G, Harrison, D, Hughes, M, Parkinson, A, Soltysiak, B, Bandmann, O, Bradbury, A, Gill, P, Fairtlough, H, Fillingham, K, Foustanos, I, Tidswell, K., Kaelin, André, Quarrel O.W., Handley O., O'Donovan K., Dumoulin C., Ramos-Arroyo M., Biunno I., Bauer P., Kline M., Capellari S., Cortelli P., Gallassi R., Landwehrmeyer G.B., European Huntington's Disease Network., Neurology, Clinical sciences, Neuroprotection & Neuromodulation, Quarrell, Ow, Handley, O, O'Donovan, K, Dumoulin, C, Ramos Arroyo, M, Biunno, I, Bauer, P, Kline, M, Landwehrmeyer, Gb, European Huntington's Disease, Network, European Huntington's Disease, N. e. t. w. o. r. k., Rinaldi, Carlo, Salvatore, Elena, and DE MICHELE, Giuseppe

Subjects
medicine.medical_specialty, Concordance, International Cooperation, Diagnostic Errors/statistics & numerical data, Nerve Tissue Proteins, Guidelines as Topic, Bioinformatics, Sensitivity and Specificity, Article, Huntingtin Gene, Huntington's disease, Trinucleotide Repeats, Internal medicine, External quality assessment, Genetics, medicine, Humans, Nerve Tissue Proteins/genetics, Diagnostic laboratory, Genetic Testing, Genetic Testing/methods/standards, Allele, Diagnostic Errors, standard reference material, Genetics (clinical), Alleles, Huntingtin Protein, ddc:618, business.industry, international cooperation, Nuclear Proteins, Reproducibility of Results, Reference Standards, medicine.disease, CAG repeat length, Nuclear Proteins/genetics, Huntington Disease, Huntington Disease/diagnosis, Mutation, Medical genetics, reproducibility of results, mutation, business, Trinucleotide repeat expansion, Huntington Disease/diagnosis/genetics, Genetic Testing/methods
Abstract

Huntington's disease results from a CAG repeat expansion within the Huntingtin gene; this is measured routinely in diagnostic laboratories. The European Huntington's Disease Network REGISTRY project centrally measures CAG repeat lengths on fresh samples; these were compared with the original results from 121 laboratories across 15 countries. We report on 1326 duplicate results; a discrepancy in reporting the upper allele occurred in 51% of cases, this reduced to 13.3% and 9.7% when we applied acceptable measurement errors proposed by the American College of Medical Genetics and the Draft European Best Practice Guidelines, respectively. Duplicate results were available for 1250 lower alleles; discrepancies occurred in 40% of cases. Clinically significant discrepancies occurred in 4.0% of cases with a potential unexplained misdiagnosis rate of 0.3%. There was considerable variation in the discrepancy rate among 10 of the countries participating in this study. Out of 1326 samples, 348 were re-analysed by an accredited diagnostic laboratory, based in Germany, with concordance rates of 93% and 94% for the upper and lower alleles, respectively. This became 100% if the acceptable measurement errors were applied. The central laboratory correctly reported allele sizes for six standard reference samples, blind to the known result. Our study differs from external quality assessment (EQA) schemes in that these are duplicate results obtained from a large sample of patients across the whole diagnostic range. We strongly recommend that laboratories state an error rate for their measurement on the report, participate in EQA schemes and use reference materials regularly to adjust their own internal standards.

Published
2012

272. Presentation of project BONAQUA

Author

Navas, J.I., De la Roca, E., López-Sanmartín, M., López, J.R., Herrera, M., Cordero,M.L., Aragão, C., and Soares, F. y Cunha, M.E.

Subjects
patología animal, Cooperación, Acuicultura, Peces, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), Moluscos, Cultivos Marinos y Recursos Pesqueros
Abstract

Poster with pesentating BONAQUA Project. funded by the project Bonaqua (0433_BONAQUA_5_E POCTEP) financed by the EDRF (European Regional Development Fund). www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua. Poster presentación del proyecto BONAQUA se enmarca dentro del Programa de Cooperación Transfronteriza España-Portugal (POCTEP) 2007-2013 del Fondo Europeo de Desarrollo Regional (FEDER) de la Unión Europea. En él participan el Instituto Andaluz de Investigación y Formación Agraria, Pesquera, Alimentaria y de la Producción Ecológica (IFAPA), a través de su Centro Agua del Pino (Cartaya), el Instituto Português do Mar e da Atmosfera (IPMA) y la Universidade do Algarve (UAlg). Financiado por el proyecto Bonaqua (0433_BONAQUA_5_E POCTEP) financiado por el FEDER (Fondo Europeo de Desarrollo Regional). www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua.

Published
2012

273. Preliminary results on the meagre feeding rhythms, Argyrosomus regius, using self-feeders

Author

Oliveira, C.C.V., de la Roca, E., López, J.M., and Sánchez, B. y Herrera, M.

Subjects
Acuicultura, 251092 ACUICULTURA MARINA, Peces, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), Corvina, Demanda, 310400 PRODUCCION ANIMAL, Cultivos Marinos y Recursos Pesqueros
Abstract

The meagre, Argyrosomus regius, is a species with potential for Mediterranean aquaculture diversification, so the study of feeding rhythms is vital for optimizing culture protocols.In the present study we describe the feeding rhythms of meagre with a light-dark cycle. We tested three different periods of food availability: firtsly, self-feeders for 24h; secondly the opposite of the preferred period, selected in the first case; and finally, just the preferred period of feeding. The results indicated that the meagre prefers to feed during the day, and their circadian system is very flexible, being able to resynchronize depending on food availability . This study is funded by the project Bonaqua (0433_BONAQUA_5_E POCTEP) financed by the EDRF (European Regional Development Fund).www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua La corvina, Argyrosomus regius, es una especie con potencial para la diversificación de la acuicultura mediterránea, por lo que el estudio de sus ritmos alimentarios es de vital importancia para optimizar los protocolos de cultivo. En el presente estudio se describieron los ritmos alimentarios de la corvina con un ciclo luz-oscuridad. Se estudiaron tres períodos diferentes de disponibilidad de alimento: En una primera etapa, el alimento estuvo disponible a demanda durante el día completo (24 h), con el objetivo de describir el momento del día cuando esta especie prefiere alimentarse. En una segunda fase, se alimentaron durante el período opuesto al elegido en la primera fase, con el fin de evaluar la flexibilidad del sistema circadiano.; y en la tercera, se alimentaron justo durante la fase preferida de alimentación, para determinar cuánto tiempo tardaban los peces en volver a sus preferencias iniciales. Los presentes resultados sugieren que la corvina prefiere alimentarse durante el día, y su sistema circadiano es muy flexible, siendo capaz de resincronizarse en función de la disponibilidad de alimento. Este estudio está financiado por el proyecto Bonaqua (0433_BONAQUA_5_E POCTEP) financiado por el FEDER (Fondo Europeo de Desarrollo Regional). www.juntadeandalucia.es/agriculturaypesca/ifapa/bonaqua. &nbsp

Published
2012

274. Diagnóstico y tratamiento precoz del carcinoma renal de riñón nativo en trasplante renal

Author

García Álvarez,T., Mazuecos Blanca,A., Navas García,N., Calle García,L., Vallejos Roca,E., Moreno Salazar,A., Soto Villalba,J., Collantes Mateos,R., and Rivero Sánchez,M.

Subjects
Trasplante renal, Carcinoma de células renales, Riñón nativo
Abstract

Antecedentes: La frecuencia de tumores en pacientes con trasplante renal (TR) está aumentando. El carcinoma de células renales (CCR) en riñones nativos es uno de los más frecuentes y su evolución puede ser más agresiva que en la población general. Objetivo: Evaluar la incidencia y pronóstico del CCR en los pacientes sometido a a trasplante renal de nuestra unidad. Métodos: Desde enero de 1997 hasta diciembre de 2009 se realizaron en nuestro hospital 683 TR. Para la detección precoz de esta patología, en todos los pacientes sometidos a trasplante realizamos una ecografía abdominal anual de forma sistemática. Los casos sospechosos se confirmaron con tomografía computarizada (TC) antes de proceder a la nefrectomía. Resultados: Por sospecha de CCR se realizaron 14 nefrectomías radicales en 12 pacientes. En 11 nefrectomías (correspondientes a 9 pacientes), el diagnóstico anatomopatológico fue de CCR (incidencia del 1,5%). Todos fueron diagnosticados en estadio T1N0M0. En los tres pacientes restantes, en los que no se detectó tumor, el diagnóstico fue de quiste renal complicado en el contexto de poliquistosis hepatorrenal. En los pacientes con CCR, el tiempo en diálisis antes del diagnóstico fue de 36,7 ± 24,3 meses y el intervalo entre el TR y el diagnóstico fue de 39 ± 25,8 meses. Tras un seguimiento medio de 58,6 ± 38,6 meses, la evolución en todos ha sido excelente, sin recurrencia del tumor. Conclusiones: La realización de ecografías anuales permite un diagnóstico precoz del CCR. El tratamiento de esta patología en estadios iniciales se asocia con un excelente pronóstico en los pacientes con TR.

Published
2011

275. Diagnóstico y tratamiento precoz del carcinoma renal de riñón nativo en trasplante renal

Author

García Álvarez, T., Mazuecos Blanca, A., Navas García, N., Calle García, L., Vallejos Roca, E., Moreno Salazar, A., Soto Villalba, J., Collantes Mateos, R., and Rivero Sánchez, M.

Subjects
Trasplante renal, Carcinoma de células renales, Renal transplantation, Native kidney, Renal cell carcinoma, Riñón nativo
Abstract

Antecedentes: La frecuencia de tumores en pacientes con trasplante renal (TR) está aumentando. El carcinoma de células renales (CCR) en riñones nativos es uno de los más frecuentes y su evolución puede ser más agresiva que en la población general. Objetivo: Evaluar la incidencia y pronóstico del CCR en los pacientes sometido a a trasplante renal de nuestra unidad. Métodos: Desde enero de 1997 hasta diciembre de 2009 se realizaron en nuestro hospital 683 TR. Para la detección precoz de esta patología, en todos los pacientes sometidos a trasplante realizamos una ecografía abdominal anual de forma sistemática. Los casos sospechosos se confirmaron con tomografía computarizada (TC) antes de proceder a la nefrectomía. Resultados: Por sospecha de CCR se realizaron 14 nefrectomías radicales en 12 pacientes. En 11 nefrectomías (correspondientes a 9 pacientes), el diagnóstico anatomopatológico fue de CCR (incidencia del 1,5%). Todos fueron diagnosticados en estadio T1N0M0. En los tres pacientes restantes, en los que no se detectó tumor, el diagnóstico fue de quiste renal complicado en el contexto de poliquistosis hepatorrenal. En los pacientes con CCR, el tiempo en diálisis antes del diagnóstico fue de 36,7 ± 24,3 meses y el intervalo entre el TR y el diagnóstico fue de 39 ± 25,8 meses. Tras un seguimiento medio de 58,6 ± 38,6 meses, la evolución en todos ha sido excelente, sin recurrencia del tumor. Conclusiones: La realización de ecografías anuales permite un diagnóstico precoz del CCR. El tratamiento de esta patología en estadios iniciales se asocia con un excelente pronóstico en los pacientes con TR. Background: The frecuency of malignancies in renal transplant (RT) patients is increasing. Renal cell carcinoma (RCC) of native kidneys is one of the most frequent and its outcome can be more aggressive than in general population. Objetive: To evaluate the incidence and prognosis of RCC in renal transplant patients followed in our transplantation unit. Methods: Between January 1997 and December 2009, 683 patients underwent kidney transplant at our hospital. Ultrasonography of the native kidneys was annually performed in all renal transplant patients. When suspect solid masses were found at ultrasonography, patients underwent computed tomography. If the suspicion was confirmed, nephrectomy was performed. Results: 14 radical nephrectomies were performed in 12 patients due to suspect CCR. In 11 nephrectomies (corresponding to 9 patients), anatomopathologic diagnosis was CCR (incidence 1.5%). Histologic stage was T1N0M0 in all cases. In the other 3 RT, the diagnosis was complicated renal cyst. Those patients without carcinoma had polycystic kidney disease. The time on dialysis before CCR diagnosis was 36.7 ± 24.3 months and the interval between RT and diagnosis was 39 ± 25.8 months. After a mean follow-up of 58.6 ± 38.6 months, the outcome of all cases has been excellent, without tumor recurrence. Conclusions: Annual renal ultrasonography plays a key role in the early diagnosis of CRR. The early treatment of this pathology is associated with an excellent prognosis in RT patients.

Published
2011

279. NOD2 mosaicism in Blau syndrome

Author

Mensa-Vilaro, A, primary, De Inocencio, J, additional, Cham, W Tarng, additional, Gonzalez-Roca, E, additional, Tejada-Palacios, P, additional, Tang, S Ping, additional, Ruiz-Ortiz, E, additional, Enriquez-Merayo, E, additional, Lim, S Chin, additional, Magri, G, additional, Plaza, S, additional, Anton, MC, additional, Cerutti, A, additional, Ariffin, R, additional, Yagüe, J, additional, and Arostegui, JI, additional

Published
2015
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280. A family carrying a homozygous LACC1 truncated mutation expands the clinical phenotype of this disease beyond systemic-onset juvenile idiopathic arthritis

Author

Arostegui, JI, primary, Rabionet, R, additional, Remesal, A, additional, Mensa-Vilaro, A, additional, Murias, S, additional, Alcobendas, R, additional, Gonzalez-Roca, E, additional, Dreschsel, O, additional, Ruiz-Ortiz, E, additional, Puig, A, additional, Comas, D, additional, Ossowski, S, additional, Yagüe, J, additional, Estivill, X, additional, and Merino, R, additional

Published
2015
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281. Somatic NLRP3 mosaicism in Muckle-Wells syndrome

Author

Gonzalez-Roca, E, primary, Mensa-Vilaro, A, additional, Plaza, S, additional, Anton, MC, additional, Rius, J, additional, Ruiz-Ortiz, E, additional, Campistol, JM, additional, Souto, A, additional, Cañellas, J, additional, Nakagawa, K, additional, Nishikomori, R, additional, Yagüe, J, additional, and Arostegui, JI, additional

Published
2015
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282. Clinical and genetic features of Spanish patients with Mevalonate kinase deficiency

Author

Ruiz-Ortiz, E, primary, Gonzalez-Roca, E, additional, Mensa-Vilaro, A, additional, Rius, J, additional, Plaza, S, additional, Anton, C, additional, Calvo, I, additional, Modesto, C, additional, Anton, J, additional, Arnal, C, additional, Alvarez, C, additional, Alvarez-Coca, J, additional, Becerra, E, additional, Bilbao, N, additional, Camacho, M, additional, Crespo, J, additional, de Diego, C, additional, Diez-Garcia, LF, additional, Espinosa, L, additional, Garcia-Escriva, D, additional, de Gracia, F, additional, Gonzalez, MI, additional, Iglesias, E, additional, Izquierdo, S, additional, Lastra, B, additional, Llobet, P, additional, Lopez, B, additional, Lopez-Gonzalez, V, additional, Martinez, R, additional, Martin-Mateos, MA, additional, Merino, R, additional, Ortega, L, additional, Peiro, ME, additional, de Soto, I Perez, additional, Perez-Mendez, C, additional, Rodriguez-Valverde, V, additional, Ribes, A, additional, Ruiz, A, additional, Sanchez, B, additional, Santos, JL, additional, Sevilla, B, additional, Sotoca, J, additional, Vilas, J, additional, Villoria, A, additional, Yagüe, J, additional, and Arostegui, JI, additional

Published
2015
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289. Effects on growth of Dicologoglossa cuneata using two feeding strategies: feeding schedule and self-feeding

Author

de la Roca, E., Herrera, M., Hachero- Cruzado, I., Cordero, M.L.

Subjects
peces planos, alimentación, 251092 ACUICULTURA MARINA, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), Comederos, ACUICULTURA, Cultivos Marinos y Recursos Pesqueros
Abstract

The objective of this work was to study the capability of the wedge sole for using self-feeders and their daily feeding rhythm, comparing the growth between two different feeding strategies. The results showed that a week would be required to operated the self-feeding system correctly. Regarding the daily feeding rhythm, it was observed an abvious nocturnal activity . The SGR was higher in the shedule feeding treatment.This work was supported by Interreg Project 0251_ECOAQUA_5_E, financed by the EDRF (European Regional Development Fund). www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua. El objetivo de este trabajo fue estudiar la capacidad de la acedía de usar comederos de autodemanda y su ritmo alimenticio diario, comparando en crecimiento entre dos estrategias alimenticias diferentes. Los resultados mostraron que las acedías necesitaron una semana para activar los comederos correctamente. En cuanto al ritmo alimenticio diario, se observó una clara actividad nocturna. La SGR fue más alta en la estrategia de alimentación programada Este trabajo fue apoyado por el proyecto Interreg 0251_ECOAQUA_5_E , financiado por el FEDER (Fondo Europeo de Desarrollo Regional).www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua.

Published
2010

290. A pareto-based systematic design technique for reconfigurable analog circuits using an evolutionary optimization algorithm

Author

Velasco-Jiménez, Manuel, Castro-López, R., Roca, E., and Fernández, Francisco V.

Subjects
Reconfigurable analog circuits, Evolutionary algorithm, Pareto-optimal front, Performance trade-off
Abstract

Trabajo presentado al XXV DCIS celebrado en Lanzarote del 17 al 19 de noviembre de 2010., In this paper, a technique to systematically design analog reconfigurable integrated circuits is presented. The methodology is based on a simulation-based optimization process that uses an evolutionary multi-objective algorithm. As it is well known, this kind of algorithms relies in the concept of Paretobased dominance. To cope with the complexity of reconfiguration in analog circuits, this concept is appropriately re-defined here with the notion of multi-mode Pareto-optimal fronts. The proposed solution is tested against a set of experiments to design a reconfigurable, fully-differential operational amplifier, whose performance trade-offs can be analyzed following the reported methodology. Moreover, some directions are given on the use of the resulting multi-mode Pareto-optimal fronts in a hierarchical synthesis methodology of reconfigurable analog circuits., This work has been supported in part by the TIC-2532 Project, funded by Consejería de Innovación, Ciencia y Empresa, Junta de Andalucía, in part by the Projects TEC2007-67247 and TEC2010-14825 funded by the Spanish Ministry of Science and Innovation with support from ERDF, and in part by Project INTRAMURALES 200950I050 funded by CSIC.

Published
2010

291. Can we use mussels as biological purifier in a hatchery?

Author

Martínez Pita, I., Sánchez Lazo, C., de la Roca, E.

Subjects
Calidad del agua, Cefalópodos, 251092 ACUICULTURA MARINA, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), Alimentación, ACUICULTURA, mejillón, Criadero de peces, Cultivos Marinos y Recursos Pesqueros
Abstract

The objective of this study was to study if the mussel Mytilus galloprovincialis could feeding on organic material from residual water of a hatchery with fishes and cephalopods without consequences for the mussel survival and condition. The mussels were maintained during 3 months and an initial sample of condition index and gonadal development were made. Survival was measured every day and total value was 90 %. The condition index was stable the first two months but it fell down the last one. Finally water was filtered at the entry and exit of the tank to value the material organic content and it ranged between 30 and 1.2 g. Then mussels can be use to improve water quality in hatchery without affecting animal condition.This work was supported by Interreg Project 0251_ECOAQUA_5_E, financed by the EDRF (European Regional Development Fund). www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua El objetivo principal de este trabajo es conocer si un organismo filtrador como es el mejillón (Mytilus galloprovincialis), es capaz de alimentarse de la materia orgánica generada por los animales mantenidos en el criadero, peces y cefalópodos en este caso; sin que el propio animal se vea afectado. Para ellos se colocaron 200 mejillones en un tanque de 3000 litros en el que desembocaba parte del agua residual de la planta piloto del IFAPA Centro Agua del Pino. Los mejillones se mantuvieron en el tanque tres meses. Se hizo un primer muestreo inicial de los mejillones para obtener su índice de condición y su estadío gonadal y luego uno mensual. Diariamente durante un mes, se observó la supervivencia y se tomaron medidas del flujo de entrada y de salida, de la temperatura, salinidad y del pH. Además, dos veces en semana se filtró el agua de entrada y de salida para calcular la materia orgánica que se eliminaba. Los valores de materia orgánica eliminada durante este mes fluctuaron entre 30 g y 1.2 g diarios, siendo el valor medio de 14.84 g. Los datos de temperatura, salinidad y pH no variaron durante el experimento y las diferencias de estos parámetros en el agua de entrada y de salida no fueron significativas. La mortalidad fue del 10 %, encontrándose concentrada en los cuatro primeros días. Respecto al índice de condición destacar que se mantuvo estable durante los dos primeros meses y luego disminuyó significativamente en el último mes. Esta disminución puede deberse al propio ciclo reproductivo de la especie, probablemente por la reabsorción de la gónada tras el periodo de maduración y puesta.Por tanto los resultados obtenidos nos permiten afirmar que el mejillón se puede utilizar satisfactoriamente para mejorar la calidad del agua ya que es capaz de eliminar hasta 30 gramos de materia orgánica al día sin que la condición del animal se vea afectada.Este trabajo fue apoyado por el proyecto Interreg 0251_ECOAQUA_5_E , financiado por el FEDER (Fondo Europeo de Desarrollo Regional). www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua

Published
2010

292. Applicability of magnetic fabrics in rocks associated with the emplacement of salt structures (the Bicorb-Quesa and Navarre´s salt walls, Prebetics, SE Spain)

Author

Soto, Ruth, Beamud, Elisabet, Oliva-Urcia, Belén, Roca, E., Rubinat, M., Villalaín, Juan J., Soto, Ruth, Beamud, Elisabet, Oliva-Urcia, Belén, Roca, E., Rubinat, M., and Villalaín, Juan J.

Abstract

This work assesses the applicability of the analysis of the anisotropy of magnetic susceptibility (AMS) to rocks associated with salt structures. Magnetic fabrics from 16 sites sampled on Upper Triassic clays (Keuper facies) interbedded within the salt layers of the Bicorb-Quesa and Navarre´s salt walls (Prebetic Zone, SE Spain) are mostly characterized by oblate magnetic ellipsoids with their magnetic foliation parallel to the bedding and magnetic lineation contained in the bedding plane but without a constant relationship with dip direction. To evaluate the quality and significance of the low-field AMS, several experiments were carried out to characterize the magnetic mineralogy of representative samples and enable separation of the contributions from paramagnetic and ferromagnetic (s.l.) minerals. The comparison between the orientation of the observed magnetic lineation and that of the structural elements characterizing the internal geometry of the studied salt structures (antiforms, minor folds, faults and shear zones) and flanks indicates that the magnetic fabric is controlled by deformation processes affecting the salt walls during their growth and/or evolution. Samples were also analyzed from sixteen sites from Miocene rocks outcropping in several syn-diapiric Miocene half-grabens related to the salt walls studied. Their magnetic fabric is interpreted to reflect the dominant stretching direction at the syn-diapiric half grabens during and/or shortly after deposition. Our results indicate that caution is required in interpreting magnetic lineations related to salt flow mechanics from rocks associated with salt structures.

Published
2014

293. Does Purchasing Power Parity hold? New Evidence from Wild-bootstrapped Nonlinear Unit Root Tests in the Presence of Heteroskedasticity

Author

Su, J., Cheung, Adrian, Roca, E., Su, J., Cheung, Adrian, and Roca, E.

Abstract

In spite of the extensive research which has already been undertaken, the issue as to whether Purchasing Power Parity (PPP) empirically holds, continues to be strongly debated. Existing studies have been criticized for their reliance on unit root tests which are deemed to suffer from certain weaknesses such as the size distortion bias arising from heteroskedasticity. In this paper, we provide new evidence on PPP based on a new methodology that overcomes this problem. We use the widely accepted KSS (Kapetanios et al., 2003) non-linear unit root tests which we, however, wild bootstrapped. Through Monte Carlo simulation, we demonstrate that the wildbootstrapped KSS is robust to heteroskedasticity-induced size distortion problem. We apply this method to test PPP across 61 countries over the period 1994 to 2012 — a period characterized by a number of crises such as the Asian Financial Crisis, Russian Crisis, dotcom crisis, Global Financial Crises, among others, and therefore, intense heteroskedasticity. Our results provide strong evidence against PPP. This paper contributes to both the international financial economics and econometrics literatures.

Published
2014

294. Influence of different culture conditions on the growth and the survival of the wedge sole (Dicologoglossa cuneata Moreau, 1881)

Author

De la Roca, E., Herrera, M., Hachero, I., Navas, J.I., and Cordero, M.L.

Subjects
Producción pesquera, Acuicultura, Recursos pesqueros, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), Cultivos Marinos y Recursos Pesqueros
Abstract

Several wedge sole (D.) juvenile batches were reared at different culture conditions in order to study the growth and survival. The variables studied were stocking density, type of substrate (with and without sand) and light intensity. The trials lasted 189, 325 and 96 days, respectively. The initial fish size varied between 0,31 and 1,42 g. Significant differences were not found for SGR in any experiment. Regards the survival, differences were only observed in the density trial, the survival varying inversely with the density. Varios grupos de juveniles de acedía fueron cultivados bajo diferentes condiciones de cultivo con el fin de estudiar el crecimiento y la supervivencia. Las variables estudiadas fueron densidad de cultivo, tipo de sustrato (con y sin arena) e intensidad lumínica. Los ensayos duraron 189, 325 y 96 días, respectivamente. El peso inicial de los peces varió entre 0,31 y 1,42 g. No fueron encontradas diferencias significativas entre los SGR de ningún experimento. En cuanto a la supervivencia, se observaron diferencias únicamente en el ensayo de densidad de cultivo, variando ésta de manera inversa a la densidad.

Published
2009

295. Influence of different culture conditions on growt and survival of wedge sole (Dicologoglossa cuneata Moreau, 1881

Author

de la Roca, E., Herrera, M., Hachero, I., Navas, J.I., Cordero, M.L.

Subjects
Supervivencia, 251092 ACUICULTURA MARINA, 240100 BIOLOGIA ANIMAL (ZOOLOGIA), ACUICULTURA, densidad, Crecimiento, Cultivos Marinos y Recursos Pesqueros
Abstract

Several wedge sole (D. cuneata) juvenile batches were reared at different culture conditions in order to study the growth and survival. The variables studied were stocking density, type of substrate (with and without sand) and light intensity. The trials lasted 189, 325 and 96 days, respectively. The initial fish size varied between 0,31 and 1,42 g. Significant differences were not found for SGR in any experiment. Regards the survival, differences were only observed in the density trial, the survival varying inversely with the density.This work was supported by Interreg Project 0251_ECOAQUA_5_E, financed by the EDRF (European Regional Development Fund). www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua. Varios lotes de alevines de acedía (D. cuneata) fueron cultivados a diferentes condiciones de cultivo con el fin de estudiar el crecimiento y la supervivencia. Las variables estudiadas fueron la densidad, tipo de sustrato (con y sin arena) y la intensidad lumínica. Los ensayos duraron 189, 325 y 96 días, respectivamente. El tamaño de los peces inicial varió entre 0,31 y 1,42 g. No se encontraron diferencias significativas para la SGR en ningún experimento. En cuanto a la supervivencia, solo se observaron diferencias significativas en el estudio sobre densidad, siendo la supervivencia inversamente proporcional a la densidad.Este trabajo fue apoyado por el proyecto Interreg 0251_ECOAQUA_5_E , financiado por el FEDER (Fondo Europeo de Desarrollo Regional).www.juntadeandalucia.es/agriculturaypesca/ifapa/ecoaqua. &nbsp

Published
2009

298. SIMSAFADIM-CLASTIC: A new approach to mathematical 3D forward simulation modelling for terrigenous and carbonate marine sedimentation

Author

Gratacós, O., Bitzer, K., Cabrera, L., Roca, E., and Universitat de Barcelona

Subjects
Process-based, Diffusion, Carbonats, Advection, Carbonates, Sedimentació, Visualització tridimensional (Informàtica), Three-dimensional display systems, Sediment transport, Mixed terrigenous-carbonate sedimentation, Forward modelling, Sedimentation
Abstract

Most sedimentary modelling programs developed in recent years focus on either terrigenous or carbonate marine sedimentation. Nevertheless, only a few programs have attempted to consider mixed terrigenous-carbonate sedimentation, and most of these are two-dimensional, which is a major restriction since geological processes take place in 3D. This paper presents the basic concepts of a new 3D mathematical forward simulation model for clastic sediments, which was developed from SIMSAFADIM, a previous 3D carbonate sedimentation model. The new extended model, SIMSAFADIM-CLASTIC, simulates processes of autochthonous marine carbonate production and accumulation, together with clastic transport and sedimentation in three dimensions of both carbonate and terrigenous sediments. Other models and modelling strategies may also provide realistic and efficient tools for prediction of stratigraphic architecture and facies distribution of sedimentary deposits. However, SIMSAFADIM-CLASTIC becomes an innovative model that attempts to simulate different sediment types using a process-based approach, therefore being a useful tool for 3D prediction of stratigraphic architecture and facies distribution in sedimentary basins. This model is applied to the neogene Vallès-Penedès half-graben (western Mediterranean, NE Spain) to show the capacity of the program when applied to a realistic geologic situation involving interactions between terrigenous clastics and carbonate sediments.

Published
2009

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