114 results on '"Barbeau, Emmanuel J."'
Search Results
102. Patterns of Semantic Memory Impairment in Mild Cognitive Impairment
- Author
-
Joubert, Sven, primary, Felician, Olivier, additional, Barbeau, Emmanuel J., additional, Didic, Mira, additional, Poncet, Michel, additional, and Ceccaldi, Mathieu, additional
- Published
- 2008
- Full Text
- View/download PDF
103. A systematic study of topographical memory and posterior cerebral artery infarctions.
- Author
-
Busigny, Thomas, Pagès, Bérengère, Barbeau, Emmanuel J, Bled, Clara, Montaut, Emilie, Raposo, Nicolas, Albucher, Jean-François, Chollet, François, and Pariente, Jérémie
- Published
- 2014
- Full Text
- View/download PDF
104. Pure progressive amnesia: An atypical amnestic syndrome?
- Author
-
Barbeau, Emmanuel J., primary, Didic, Mira, additional, Felician, Olivier, additional, Tramoni, Eve, additional, Guedj, Eric, additional, Ceccaldi, Mathieu, additional, and Poncet, Michel, additional
- Published
- 2006
- Full Text
- View/download PDF
105. Preserved visual recognition memory in an amnesic patient with hippocampal lesions
- Author
-
Barbeau, Emmanuel J., primary, Felician, Olivier, additional, Joubert, Sven, additional, Sontheimer, Anna, additional, Ceccaldi, Mathieu, additional, and Poncet, Michel, additional
- Published
- 2005
- Full Text
- View/download PDF
106. MR, 18F-FDG, and 18F-AV45 PET Correlate With AD PSEN1 Original Phenotype.
- Author
-
Saint-Aubert, Laure, Payoux, Pierre, Hannequin, Didier, Barbeau, Emmanuel J., Campion, Dominique, Delisle, Marie-Bernadette, Tafani, Mathieu, Viallard, Gérard, Péran, Patrice, Puel, Michèle, Chollet, François, Demonet, Jean-François, and Pariente, Jérémie
- Abstract
The article presents a case study of a 37-year-old man who was admitted to the hospital with complaints of progressive gait disorder followed by cognitive difficulties. His structural magnetic resonance imaging (MRI) scan revealed posterior cortical atrophy on T1 sequence. His thorough analysis revealed a higher bilateral hippocampal AV45 uptake in patient than in patients with Alzheimer's disease.
- Published
- 2013
- Full Text
- View/download PDF
107. Amyloid Imaging with AV45 (18F-florbetapir) in a Cognitively Normal AβPP Duplication Carrier.
- Author
-
Saint-Aubert, Laure, Planton, Mélanie, Hannequin, Didier, Albucher, Jean-François, Delisle, Marie-Bernadette, Payoux, Pierre, Hitzel, Anne, Viallard, Gérard, Péran, Patrice, Campion, Dominique, Laquerrière, Annie, Barbeau, Emmanuel J., Puel, Michéle, Raposo, Nicolas, Chollet, François, and Pariente, Jérémie
- Subjects
GENETICS of Alzheimer's disease ,CHROMOSOME duplication ,AMYLOID ,MAGNETIC resonance imaging ,NEUROLOGICAL disorders - Abstract
We report the case of a 62-year-old asymptomatic carrier of AβPP gene duplication. He was investigated by MRI and the amyloid ligand
18 F-AV45, and compared to Alzheimer's disease patients (n = 11) and healthy controls (n = 11). The neuropsychological examination was normal. Cortical thickness and AV45 retention were comparable to Alzheimer's disease patients. AβPP duplication was diagnosed because cerebral amyloid angiopathy and Alzheimer's disease pathology were found on the neuropathological examination of his youngest brother, who died at 42 from intracerebral hemorrhage. This is the first description of a pre-symptomatic AβPP duplication carrier over 60, despite widespread cerebral amyloid angiopathy, 'Alzheimer's like' atrophy, and amyloid deposition. [ABSTRACT FROM AUTHOR]- Published
- 2012
- Full Text
- View/download PDF
108. Visual recognition memory: A double anatomo-functional dissociation.
- Author
-
Barbeau, Emmanuel J., Pariente, Jérémie, Felician, Olivier, and Puel, Michèle
- Abstract
There is an ongoing debate regarding the respective role of anterior subhippocampal structures and the hippocampus in recognition memory. Here, we report a double anatomo-functional dissociation observed in two brain-damaged patients, FRG and JMG. They both suffered from complete destruction of left MTL structures. In the right hemisphere however, FRG sustained extensive lesions to the hippocampus sparing anterior subhippocampal structures, while JMG suffered from the reversed pattern of lesion, i.e., extensive damage to anterior subhippocampal structures but preserved hippocampus. FRG was severely amnesic and failed all recall tasks involving visual material, but exhibited normal performance at a large battery of visual recognition memory tasks. JMG was not amnesic and showed the opposite pattern of performance. These results strongly support the view that right anterior subhippocampal structures are a critical relay for visual recognition memory in the human. © 2010 Wiley-Liss, Inc. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
109. Ultra-Rapid Sensory Responses in the Human Frontal Eye Field Region.
- Author
-
Kirchner, Holle, Barbeau, Emmanuel J., Thorpe, Simon J., Régis, Jean, and Liégeois-Chauvel, Catherine
- Subjects
- *
SENSORY receptors , *EYE movements , *BRAIN , *AUDITORY cortex , *VISUAL learning , *EPILEPSY - Abstract
Most of what we know about the human frontal eye field (FEF) is extrapolated from studies in animals. There is ample evidence that this region is crucial for eye movements. However, evidence is accumulating that this region also plays a role in sensory processing and that it belongs to a "fast brain" system. We set out to investigate these issues in humans, using intracerebral recordings in patients with drug-refractory epilepsy. Event-related potential recordings were obtained from 11 epileptic patients from within the FEF region while they passed a series of visual and auditory perceptual tests. No eye movement was required. Ultra-rapid responses were observed, with mean onset latencies at 24 ms after stimulus to auditory stimuli and 45 ms to visual stimuli. Such early responses were compatible with cortical routes as assessed with simultaneous recordings in primary auditory and visual cortices. Components were modulated very early by the sensory characteristics of the stimuli, in the 30-60 ms period for auditory stimuli and in the 45- 60 ms period for visual stimuli. Although the frontal lobes in humans are generally viewed as being involved in high-level cognitive processes, these results indicate that the human FEF is a remarkably quickly activated multimodal region that belongs to a network of low-level neocortical sensory areas. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
110. Subhippocampal dysfunction as a clinical marker of incipient Alzheimer's disease
- Author
-
Didic Hamel Cooke, Mira, Barbeau, Emmanuel J., Felician, Olivier, Guedj, Eric, Ranjeva, Jean-Philiphe, Cozzone, Patrick, and Ceccaldi, Mathieu
- Published
- 2009
- Full Text
- View/download PDF
111. Cognitive Maps Exploration trough Kernel Density Estimation
- Author
-
Antoine Lhuillier, Christophe Hurter, Hélène Amieva, Barbeau, Emmanuel J., Christophe Jouffrais, ENAC - Equipe Informatique Interactive (LII), Ecole Nationale de l'Aviation Civile (ENAC), Etude de L’Interaction Personne SystèmE (IRIT-ELIPSE), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche cerveau et cognition (CERCO), Institut des sciences du cerveau de Toulouse. (ISCT), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), University of Maryland, Vienna University of Technology, LHUILLIER, Antoine, Université Toulouse Capitole (UT Capitole), Université Fédérale Toulouse Midi-Pyrénées-Toulouse Mind & Brain Institut (TMBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse Capitole (UT Capitole), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Cognitive maps ,Large data visualization ,Bundling ,[INFO.INFO-HC]Computer Science [cs]/Human-Computer Interaction [cs.HC] ,[INFO.INFO-HC] Computer Science [cs]/Human-Computer Interaction [cs.HC] ,PAQUID ,Alzheimer ' s disease - Abstract
Electronic Health Record (EHR); International audience; Currently approximately 860,000 people are affected by Alzheimer’s disease in France. This is why the study of Alzheimer’s disease has been identified as a major societal challenge. In the PAQUID cohort study, subjects performed a lexical evocation task by saying the maximum number of city names within 3 minutes. This task is directly related to the concept of cognitive map. The analysis of the list created by this task provides a unique opportunity to study the spatial mental representation of geographical space for elderly people before and after developing the dementia. We visualized graphs of this list by connecting cited city with a line. Since these graphs become cluttered with numerous lines, we applied the KDEEB bundling technique. We then compared graphs representing different periods before and after dementia. Our first results show that graph complexity is related to aging, as well as the clinical status of the subject. The ultimate goal of the project is to develop techniques and tools to study the cognitive maps of elderly subjects in the years preceding Alzheimer’s disease. The tools that will be developed shall rely on image based technique (e.g. bundling) and help to better detect and understand the evolution of Alzheimer’s disease.
112. Robust thalamic nuclei segmentation from T1-weighted MRI using polynomial intensity transformation.
- Author
-
Vidal JP, Danet L, Péran P, Pariente J, Cuadra MB, Zahr NM, Barbeau EJ, and Saranathan M
- Abstract
Accurate segmentation of thalamic nuclei, crucial for understanding their role in healthy cognition and in pathologies, is challenging to achieve on standard T1-weighted (T1w) magnetic resonance imaging (MRI) due to poor image contrast. White-matter-nulled (WMn) MRI sequences improve intrathalamic contrast but are not part of clinical protocols or extant databases. In this study, we introduce histogram-based polynomial synthesis (HIPS), a fast preprocessing transform step that synthesizes WMn-like image contrast from standard T1w MRI using a polynomial approximation for intensity transformation. HIPS was incorporated into THalamus Optimized Multi-Atlas Segmentation (THOMAS) pipeline, a method developed and optimized for WMn MRI. HIPS-THOMAS was compared to a convolutional neural network (CNN)-based segmentation method and THOMAS modified for T1w images (T1w-THOMAS). The robustness and accuracy of the three methods were tested across different image contrasts (MPRAGE, SPGR, and MP2RAGE), scanner manufacturers (PHILIPS, GE, and Siemens), and field strengths (3T and 7T). HIPS-transformed images improved intra-thalamic contrast and thalamic boundaries, and HIPS-THOMAS yielded significantly higher mean Dice coefficients and reduced volume errors compared to both the CNN method and T1w-THOMAS. Finally, all three methods were compared using the frequently travelling human phantom MRI dataset for inter- and intra-scanner variability, with HIPS displaying the least inter-scanner variability and performing comparably with T1w-THOMAS for intra-scanner variability. In conclusion, our findings highlight the efficacy and robustness of HIPS in enhancing thalamic nuclei segmentation from standard T1w MRI.
- Published
- 2024
- Full Text
- View/download PDF
113. Improving the integrative memory model by integrating the temporal dynamics of memory.
- Author
-
Curot J and Barbeau EJ
- Subjects
- Humans, Memory Disorders, Memory, Mental Recall
- Abstract
Despite highlighting the role of the attribution system and proposing a coherent large-scale architecture of declarative memory, the integrative memory model would be more "integrative" if the temporal dynamics of the interactions between its components was clarified. This is necessary to make predictions in patients with brain injury and hypothesize dissociations.
- Published
- 2020
- Full Text
- View/download PDF
114. How Fast is Famous Face Recognition?
- Author
-
Barragan-Jason G, Lachat F, and Barbeau EJ
- Abstract
The rapid recognition of familiar faces is crucial for social interactions. However the actual speed with which recognition can be achieved remains largely unknown as most studies have been carried out without any speed constraints. Different paradigms have been used, leading to conflicting results, and although many authors suggest that face recognition is fast, the speed of face recognition has not been directly compared to "fast" visual tasks. In this study, we sought to overcome these limitations. Subjects performed three tasks, a familiarity categorization task (famous faces among unknown faces), a superordinate categorization task (human faces among animal ones), and a gender categorization task. All tasks were performed under speed constraints. The results show that, despite the use of speed constraints, subjects were slow when they had to categorize famous faces: minimum reaction time was 467 ms, which is 180 ms more than during superordinate categorization and 160 ms more than in the gender condition. Our results are compatible with a hierarchy of face processing from the superordinate level to the familiarity level. The processes taking place between detection and recognition need to be investigated in detail.
- Published
- 2012
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.