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Is it the heavy industry or light industry that performs better in energy efficiency incorporating undesirable outputs? Energy efficiency is the gap between actual and target energy inputs, thus the more energy intensive heavy industry is not necessarily the less energy efficient one. The purpose of this paper is to evaluate and compare the ecological total-factor energy efficiency (ETFEE) of the heavy and light industries as well as to assess their technology gaps. Considering the slack-bias of conventional DEA models and technological heterogeneity between heavy and light industries, the slack-based DEA model (SBM) and meta-frontier technology have been combined. The empirical results show that: (1) China's industries did not perform efficiently. Among them, heavy industry, albeit has more advanced technology, demonstrates lower energy efficiency than light industry. Thus, China needs to stimulate heavy industry to achieve its potential in efficiency improvement. (2) Compared with light industry, governmental stimulus induced expansion has promoted technological advancement in heavy industry, but it still has had no effect on the utilization of existing technologies by, for example, improving the managerial efficiency. Greater pressure on environmental standards is needed to motivate factories in heavy industry to utilize existing technologies more sufficiently. (3) Technological gap among industries has enlarged, thus more attention should be paid on encouraging technology spillover from heavy industry to light industry. [ABSTRACT FROM AUTHOR]

AbstractThis study explores the underexplored application of benchmarking in Corporate Social Responsibility (CSR) among Chinese A-listed companies from 2010 to 2020. The results reveal a positive relationship between CSR performance and local best practices, indicating benchmarking’s influence on CSR activities. Notably, benefits like increased market value, robust revenue, and heightened analyst attention signify positive market signals, motivating companies to enhance their CSR performance. The impacts on CSR performance varies significantly based on leader companies’ CSR scores, ages, and follower companies’ ownership properties, sizes, and locations. Our findings offer valuable insights into CSR motivations and the performance effects of best practices. [ABSTRACT FROM AUTHOR]

Frequency-modulated continuous-wave (FMCW) narrow linewidth lasers have served as the cornerstone behind applications such as autonomous driving, wearable technology, virtual reality, and remote sensing mapping. Strongly coherent lasers are typically used for these studies, with a clear demand for linear fast response and wide frequency tuning range. In this paper, profiting from the ultrahigh-quality factor of the crystalline whispering-gallery-mode resonator, by using a self-injection locking mechanism to suppress spontaneous emission noise and improve coherence, sub-kHz linewidth at 450 nm is obtained. Furthermore, based on the dispersive response principle, fast electrical tuning is realized by using the strain-influenced resonator, and the experimental test result reaches 81 pm/V. More importantly, we demonstrate the comprehensive performance of this type of FMCW laser in underwater detection, with a sensitivity of 319 MHz/m at a chirp frequency of 1 kHz.

Background: Intervertebral disc degeneration (IVDD) is a major cause of low back pain (LBP), worsened by chronic inflammatory processes associated with aging. Tumor necrosis factor alpha (Tnf-α) and its receptors, Tnf receptor type 1 (Tnfr1) and Tnf receptor type 2 (Tnfr2), are upregulated in IVDD. However, its pathologic mechanisms remain poorly defined., Methods: To investigate the role of Tnfr in IVDD, we generated global Tnfr1/2 double knockout (KO) mice and age-matched control C57BL/6 male mice, and analyzed intervertebral disc (IVD)-related phenotypes of both genotypes under physiological conditions, aging, and lumbar spine instability (LSI) model through histological and immunofluorescence analyses and μCT imaging. Expression levels of key extracellular matrix (ECM) proteins in aged and LSI mice, especially markers of cell proliferation and apoptosis, were evaluated in aged (21-month-old) mice., Results: At 4 months, KO and control mice showed no marked differences of IVDD-related parameters. However, at 21 months of age, the loss of Tnfr expression significantly alleviated IVDD-like phenotypes, including a significant increase in height of the nucleus pulposus (NPs) and reductions of endplates (EPs) porosity and histopathological scores, when compared to controls. Tnfr deficiency promoted anabolic metabolism of the ECM proteins and suppressed ECM catabolism. Tnfr loss largely inhibited hypertrophic differentiation, and, in the meantime, suppressed cell apoptosis and cellular senescence in the annulus fibrosis, NP, and EP tissues without affecting cell proliferation. Similar results were observed in the LSI model, where Tnfr deficiency significantly alleviated IVDD and enhanced ECM anabolic metabolism while suppressing catabolism., Conclusion: The deletion of Tnfr mitigates age-related and LSI-induced IVDD, as evidenced by preserved IVD structure, and improved ECM integrity. These findings suggest a crucial role of Tnf-α/Tnfr signaling in IVDD pathogenesis in mice. Targeting this pathway may be a novel strategy for IVDD prevention and treatment., Competing Interests: The authors declare that they have no competing financial interests., (© 2024 The Author(s). JOR Spine published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.)

Ethnopharmacological Relevance: Bei Qi Wu Jia (BQWJ), a modern preparation of a traditional Chinese medicinal formula, is a combination of Radix Astragali and Acanthopanacis Senticosi. Although BQWJ has been used to treat insomnia, fatigue, and loss of appetite, toxicological safety studies are rare in the literature., Aim of the Study: To evaluate the acute and subacute toxicity of BQWJ extract after oral administration in mice and rats, respectively., Materials and Methods: In the acute toxicity study, mice underwent oral administration of 67.5 g extract/kg/day. In the subacute toxicity study, rats underwent a single oral administration of 1.25, 2.5, 5.0, or 10.0 g/kg/day of BQWJ extract for 28 days. The animals' general behavior, body weight, food intake, biochemical and hematologic parameters, organ coefficients, and pathological morphology were analyzed., Results: No evidence of toxicity was observed in the mice after acute exposure to BQWJ extract. The subacute results included no deaths and no changes in general behavior. Although BQWJ extract resulted in some significant changes in other parameters, these alterations cannot be considered treatment-related because they remained within normal ranges throughout the 28 days., Conclusions: In conclusion, the oral administration of BQWJ extract at doses of less than 67.5 g/kg/day for 1 day or 10.0 g/kg/day for 28 consecutive days can be considered safe and showed no distinct toxicity or side effects in this study., (Copyright © 2019 Elsevier B.V. All rights reserved.)