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104. Contributors

Author

ACKLIN, YVES PASCAL, ADAMS, JULIE E., AMOROSA, LOUIS F., ANDERMAHR, JONAS, ANDERSEN, ROMNEY C., ANDERSON, CAESAR A., ANDERSON, PAUL A., AWAD, BASEM I., BAILEY, CHRISTOPHER S., BALACH, TESSA, BALDWIN, PAUL C., III, BARTLETT, CRAIG S., III, BAUMGAERTNER, MICHAEL R., BECHTOLD, JOAN ELIZABETH, BELIN, ERIC J., BELLABARBA, CARLO, BENNINGER, EMANUEL D.L., BHALLA, KAVI, BINDRA, RANDY R., BLEASE, ROBERT, BORN, CHRISTOPHER T., BOSSE, MICHAEL J., BRANSFORD, RICHARD JACKSON, BRINKER, MARK R., BROWNER, BRUCE D., CALFEE, RYAN, CASSIDY, CHARLES, CASTILLO, RENAN C., CELESTRE, PAUL C., CHANDAWARKAR, RAJIV, COHEN, MARK, COLE, PETER A., COLTON, CHRISTOPHER L., COONEY, LEO M., JR., COOPER, BRIAN W., COUGHLIN, R. RICHARD, DALZELL, KRISTIAN, DAS, NANDITA, DECKER, SEBASTIAN, DIGIOVANNI, CHRISTOPHER W., Dimar, John R., II, DIRSCHL, DOUGLAS R., DUFFY, RYAN, FEHLINGS, MICHAEL G., FELDMAN, DEBORAH, FELICIANO, DAVID V., FINN, MICHAEL, FRANCE, JOHN C., FREEDMAN, BRETT A., GANNON, RICHARD, GARY, JOSHUA L., GAULKE, RALPH, GEBHARD, FLORIAN, GERLINGER, TAD, GHOBRIAL, GEORGE M., GIANNOUDIS, PETER V., GIANOLI, DANIEL J., GINAITT, PETER, GOCKE, RYAN T., GOREHAM-VOSS, CURTIS, GÖSLING, THOMAS, GOSSELIN, RICHARD A., GOULET, JAMES A., GRAVES, MATT L., GREEN, STUART A., GREENE, JOHN, GUTIERREZ, DAVINA V., HAHN, JESSE C., HAIDUKEWYCH, GEORGE J., HALL, JONATHAN S., HAN, SHANNON, HANSEN, SIGVARD T., JR., HARRIS, MITCHEL B., HARROP, JAMES S., HARTLEY, BRANDI, HAWI, NAEL, HAYDA, ROMAN, HSU, JOSEPH R., JACOBSON, AARON R., JAGODZINSKI, MICHAEL, JAIN, SAMEER, JOAQUIM, ANDREI F., JONES, CLIFFORD B., JOSHIPURA, MANJUL, JOST, BERNHARD, JU, KEVIN L., JUPITER, JESSE B., KADRMAS, WARREN, KALANDIAK, STEVEN P., KATES, STEPHEN L., KLAUSMEYER, MELISSA A., KOVAL, KENNETH J., KRETTEK, CHRISTIAN, KUMAR, ASHESH, KUMAR, RAMESH, KWON, JOHN Y., KYLE, RICHARD F., LAFFERTY, PAUL M., LATTA, LOREN L., LERNER, ALEXANDER, LESLIE, MICHAEL P., LEVIN, PAUL E., LEVY, BRUCE A., LING, GEOFFREY S.F., LUDWIG, STEVEN C., LY, THUAN V., MACARTHUR, SUSAN G., MACKENZIE, ELLEN J., MAMCZAK, CHRISTIAAN N., MANOSO, MARK W., MARMOR, MEIR T., MARIANO, DEAN, MAS, PETER J., MATITYAHU, AMIR M., MATTA, JOEL M., MCKEE, MICHAEL D., MOCK, CHARLES N., MOORE, TIMOTHY, MORAFF, ADRIENNE, MORRIS, VICTOR A., MOUCHA, CALIN S., MÜLLER, CHRISTIAN W., MURDOCK, ALAN D., MURRAY, CLINTON K., NANOS, GEORGE P., III, NAUTH, AARON, NEAL, JOHN, VI, NORK, SEAN E., NOURI, ARIA, O'CONNOR, DANIEL P., OLSON, STEVEN A., OSLER, POLINA, OWENS, BRETT D., OWENS, PATRICK W., PAGENKOPF, ERIC, PALEY, DROR, PATEL, ALPESH A., PEITZMAN, ANDREW B., PERDRIZET, GEORGE A., PESANTI, EDWARD L., PETRI, MAXIMILIAN, PHAN, PHILIPPE, PINZUR, MICHAEL S., POLLAK, ANDREW, POTTER, BENJAMIN K., PRINCE, DANIEL E., PRIOR, DAVID M., PROBE, ROBERT A., RASMUSSEN, TODD E., REILLY, MARK C., RESHEF, NOAM, RICHTER, MARTINUS, RIEHL, JOHN T., RING, DAVID, ROBERTS, CRAIG S., ROSAS, HUMBERTO, ROSKOSKY, MELLISA, ROSS, JACK W., ROUTT, MILTON LEE (CHIP), JR., ROY, MICHAEL J., RUCHELSMAN, DAVID E., SANDERS, THOMAS H., SARMIENTO, AUGUSTO, SASSOON, ADAM A., SAVAGE, JASON W., SCALEA, THOMAS M., SCHATZKER, JOSEPH, SCHRODER, LISA K., SEDNEY, CARA L., SELIGSON, DAVID, SHEARER, DAVID W., SHEPPARD, RICHARD, SHULER, MICHAEL SIMMS, SILVERSTEIN, NICOLE, SOMMER, CHRISTOPH, SPIEGEL, DAVID A., SPIGUEL, ANDRE R., SPROSS, CHRISTIAN, STEFFNER, ROBERT J., STEINMANN, SCOTT P., STEINMETZ, MICHAEL P., STEVENSON, IAIN, STINNER, DANIEL J., STOCK, HARLAN, SWIONTKOWSKI, MARC F., TANNOUS, OLIVER, TILE, MARVIN, UPADHYAY, ASHISH, VACCARO, ALEXANDER R., WADDELL, JAMES P., WARDLAW, DOUGLAS, WARE, J. KRISTOPHER, WATSON, J. TRACY, WENKE, JOSEPH C., WIESEL, BRENT B., WIESEL, SAM W., WILLIAMS, SETH K., WINKELMANN, MARCEL, WOOD, KIRKHAM BERWICK, WOZNICZKA, JENNIFER, WYSOCKI, ROBERT, ZDRAVKOVIC, VILIJAM, ZIRKLE, LEWIS G., and ZYCH, GREGORY A.

Published
2015
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105. Association between the ESR1 - 351A> G single nucleotide polymorphism (rs9340799) and adolescent idiopathic scoliosis: a systematic review and meta-analysis.

Author

Chen, Suzan, Zhao, Linlu, Roffey, Darren, Phan, Philippe, and Wai, Eugene

Subjects
ADOLESCENT idiopathic scoliosis, SPINE abnormalities, SCOLIOSIS, SPINAL curvatures, SPINAL injuries, GENETICS
Abstract

Purpose: A single nucleotide polymorphism in the promoter region of the estrogen receptor alpha gene ( ESR1), rs9340799, has been linked with adolescent idiopathic scoliosis (AIS) in several association studies with limited sample size and inconsistent findings. A systematic review can provide a comprehensive appraisal of literature evidence and a meta-analysis can obtain a more precise estimate of any association. The purpose of the present study was to assess and synthesize the currently available evidence on the association between rs9340799 and AIS by conducting a systematic review and meta-analysis. Methods: This review followed the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. PubMed (MEDLINE), EMBASE, Scopus and HuGE Literature Finder databases were systematically searched to identify relevant studies following a sensitive strategy. Summary odds ratios and corresponding 95 % confidence intervals (95 % CI) were estimated using the fixed-effect inverse variance model for allelic (G vs. A) and genotypic comparisons. Results: Meta-analysis of four studies ( n = 1,827 AIS cases and n = 1,253 controls) found a non-significant association between rs9340799 and AIS (allelic odds ratio 1.09, 95 % CI 0.96-1.23, p = 0.17). Conclusions: When examined in isolation, the rs9340799 polymorphism does not appear to be a likely susceptibility variant for AIS predisposition. However, rs9340799 may be associated with AIS severity, progression and treatment; further investigation is necessary to confirm these potential associations. [ABSTRACT FROM AUTHOR]

Published
2014
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106. Preoperative expectations of patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research Network.

Author

Althagafi, Alwalaa, Dea, Nicolas, Evaniew, Nathan, Rampersaud, Raja Y., Jacobs, W. Bradley, Paquet, Jérome, Wilson, Jefferson R., Hall, Hamilton, Bailey, Christopher S., Weber, Michael H., Nataraj, Andrew, Attabib, Najmedden, Cadotte, David W., Phan, Philippe, Christie, Sean D., Fisher, Charles G., Manson, Neil, Thomas, Kenneth, McIntosh, Greg, and Charest-Morin, Raphaële

Subjects
*CLINICAL deterioration, *NECK pain, *INFORMED consent (Medical law), *LOGISTIC regression analysis, *FUNCTIONAL status
Abstract

• Most patients expected improvement in functional status and myelopathic symptoms. • The foremost desired outcome by patients was halting neurological deterioration. • Expectations predictors: comorbidities, pain, symptoms duration, no failure of other treatment. Despite an abundance of literature on degenerative cervical myelopathy (DCM), little is known about preoperative expectations of these patients. The primary objective was to describe patient preoperative expectations. Secondary objectives included identifying patient characteristics associated with high preoperative expectations and to determine if expectations varied depending on myelopathy severity. This was a retrospective study of a prospective multicenter, observational cohort of patients with DCM. Patients who consented to undergo surgical treatment between January 2019 and September 2022 were included. An 11-domain expectation questionnaire was completed preoperatively whereby patients quantified the expected change in each domain. The most important expected change was captured. A standardized expectation score was calculated as the sum of each expectation divided by the maximal possible score. The high expectation group was defined by patients who had an expectation score above the 75th percentile. Predictors of patients with high expectations were determined using multivariable logistic regression models. There were 262 patients included. The most important patient expectation was preventing neurological worsening (40.8%) followed by improving balance when standing or walking (14.5%), improving independence in everyday activities (10.3%), and relieving arm tingling, burning and numbness (10%). Patients with mild myelopathy were more likely to select no worsening as the most important expected change compared to patients with severe myelopathy (p<.01). Predictors of high patient expectations were: having fewer comorbidities (OR -0.30 for every added comorbidity, 95% CI -0.59 to -0.10, p=.01), a shorter duration of symptoms (OR 0.92, 95% CI 0.35–1.19, p=.02), no contribution from "failure of other treatments" on the decision to undergo surgery (OR 1.49, 95% CI 0.56–2.71, p=.02) and more severe neck pain (OR 0.19 for 1 point increase, 95% CI 0.05–0.37, p=.01). Most patients undergoing surgery for DCM expect prevention of neurological decline, better functional status, and improvement in their myelopathic symptoms. Stopping neurological deterioration is the most important expected outcomes by patients. [ABSTRACT FROM AUTHOR]

Published
2024
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107. Classification of Adolescent Idiopathic Scoliosis Using Kohonen Self-Organizing Maps.

Author

Aubin, Carl-Eric, Stokes, Ian A.F., Labelle, Hubert, Moreau, Alain, Phan, Philippe, Mezghani, Neila, and De Guise, Jacques A.

Abstract

Introduction: To determine curve type, Lenke classification for AIS uses strict cut-off values on radiological measurements such as Cobb angles which are known to have significant inter-observer variability. There is a documented variability in surgical treatment of AIS, yet the influence of curve types on that variability has not yet been studied. Objectives: To use an automated method to classify AIS patients using radiological measurements. Our working hypothesis is that Kohonen Self-Organizing Maps (SOM) can avoid limitations seen with classification using strict criteria. It can also highlight treatment variability depending on curve types. Methods: Pre-operative Cobb angles from 1801 surgically treated AIS cases were inputted into a neural network to generate a SOM onto which Lenke classes and fusion levels were transposed. Geometric validation of the map using threedimensional reconstruction was done and Kappa statistics were used to evaluate treatment variability. Results: SOM classify scoliotic spines with a distribution gradient for each of the parameters inputted. The levels of fusions were only homogeneous in single thoraco-lumbar curves with a kappa value of 1.0 . 71 three-dimensional reconstruction of scoliotic spines were mapped on the kohonen map showing conservation of geometrical neighbouring. Conclusion: SOM can efficiently classify AIS while respecting neighbouring of similar scoliotic spines. There is ubiquitous variability in surgical treatment of AIS with the exception of single thoraco-lumbar/lumbar curves. Significance: Such classifications will allow us to better query large database to lookup for similar cases while eliminating the limitations imposed by classifications using rigid criteria. [ABSTRACT FROM AUTHOR]

Published
2010

108. Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada.

Author

Dionne A, Al-Zakri M, Labelle H, Joncas J, Parent S, Mac-Thiong JM, Miyanji F, Lonner B, Eren A, Cahill P, Parent S, Newton P, Dermott JA, Jaakkimainen L, To T, Bouchard M, Howard A, Lebel DE, Hardy S, Malhotra AK, Dermott J, Thevarajah D, Mathias KDA, Yoon S, Sakhrekar R, Lebel DE, Kim DJ, Hadi A, Doria A, Mitani A, Dermott J, Howard A, Lebel D, Yoon S, Mathias K, Dermott J, Lebel D, Miyanji F, Newton P, Lonner B, Bastrom T, Samdani A, Roy-Beaudry M, Beauséjour M, Imbeault R, Dufresne J, Parent S, Romeo J, Livock H, Smit K, Jarvis J, Tice A, Chan VK, Cho R, Poon S, Skaggs DL, Shumilak GK, Rocos B, Sardi JP, Charalampidis A, Gum J, Lewis SJ, Tretiakov PS, Onafowokan O, Mir J, Das A, Williamson T, Dave P, Imbo B, Lebovic J, Jankowski P, Passias PG, Lewis S, Aljamaan Y, Lenke LG, Smith J, Varshney VP, Sahjpaul R, Paquette S, Osborn J, Pelletier-Roy R, Asmussen M, Birk M, Ludwig T, Nicholls F, Zohar A, Loomans J, Pellise F, Smith JS, Kato S, Sardar Z, Lenke L, Lewis SJ, Abbas A, Toor J, Sahi G, Kovacevic D, Lex J, Miyanji F, Rampersaud R, Perruccio AV, Mahomed N, Canizares M, Rizkallah M, Lebreton MA, Boubez G, Shen J, AlShakfa F, Kamel Y, Osman G, Wang Z, Koegl N, Herrington B, Fernandes RR, Urquhart JC, Rampersaud YR, Bailey CS, Hakimjavadi R, Zhang T, DeVries Z, Wai EK, Kingwell SP, Stratton A, Tsai E, Wang Z, Phan P, Rampersaud R, Fine N, Stone L, Kapoor M, Chênevert A, Bédard S, McIntosh G, Goulet J, Couture J, Investigators C, LaRue B, Rosenstein B, Rye M, Roussac A, Naghdi N, Macedo LG, Elliott J, DeMont R, Weber MH, Pepin V, Dover G, Fortin M, Wang Z, Rizkallah M, Shen J, Lebreton MA, Florial E, AlShakfa F, Boubez G, Raj A, Amin P, McIntosh G, Rampersaud YR, AlDuwaisan AASM, Hakimjavadi R, Zhang T, Phan K, Stratton A, Tsai E, Kingwell S, Wai E, Phan P, Hebert J, Nowell S, Wedderkopp N, Vandewint A, Manson N, Abraham E, Small C, Attabib N, Bigney E, Koegl N, Craig M, Al-Shawwa A, Ost K, Tripathy S, Evaniew N, Jacobs B, Cadotte D, Malhotra AK, Evaniew N, Dea N, Investigators C, McIntosh G, Wilson JR, Evaniew N, Bailey CS, Rampersaud YR, Jacobs WB, Phan PP, Nataraj A, Cadotte DW, Weber MH, Thomas KC, Manson N, Attabib N, Paquet J, Christie SD, Wilson JR, Hall H, Fisher CG, McIntosh G, Dea N, Liu EY, Persad ARL, Baron N, Fourney D, Shakil H, Investigators C, Evaniew N, Wilson JR, Dea N, Phan P, Huang J, Fallah N, Dandurand C, Alfawaz T, Zhang T, Stratton A, Tsai E, Wai E, Kingwell S, Wang Z, Phan P, Investigators C, Zaldivar-Jolissaint JF, Charest-Morin R, McIntosh G, Fehlings MG, Pedro KM, Alvi MA, Wang JCW, Charest-Morin R, Dea N, Fisher C, Dvorak M, Kwon B, Ailon T, Paquette S, Street J, Dandurand C, Mumtaz R, Skaik K, Wai EK, Kingwell S, Stratton A, Tsai E, Phan PTN, Wang Z, Investigators C, Manoharan R, McIntosh G, Rampersaud YR, Smith-Forrester J, Douglas JE, Nemeth E, Alant J, Barry S, Glennie A, Oxner W, Weise L, Christie S, Liu EY, Persad ARL, Saeed S, Toyota P, Su J, Newton B, Coote N, Fourney D, Rachevits MS, Razmjou H, Robarts S, Yee A, Finkelstein J, Almojuela A, Zeiler F, Logsetty S, Dhaliwal P, Abdelnour M, Zhang Y, Wai E, Kingwell SP, Stratton A, Tsai E, Phan PT, Investigators C, Smith TA, Small C, Bigney E, Richardson E, Kearney J, Manson N, Abraham E, Attabib N, Bond M, Dombrowski S, Price G, García-Moreno JM, Hebert J, Qiu S, Surendran V, Cheung VSE, Ngana S, Qureshi MA, Sharma SV, Pahuta M, Guha D, Essa A, Shakil H, Malhotra A, Byrne J, Badhiwala J, Yuan E, He Y, Jack A, Mathieu F, Wilson JR, Witiw CD, Shakil H, Malhotra AK, Yuan E, Smith CW, Harrington EM, Jaffe RH, Wang AP, Ladha K, Nathens AB, Wilson JR, Witiw CD, Sandarage RV, Galuta A, Tsai EC, Rotem-Kohavi N, Dvorak MF, Xu J, Fallah N, Waheed Z, Chen M, Dea N, Evaniew N, Noonan V, Kwon B, Kwon BK, Malomo T, Charest-Morin R, Paquette S, Ailon T, Dandurand C, Street J, Fisher CG, Dea N, Heran M, Dvorak M, Jaffe R, Coyte P, Chan B, Malhotra A, Hancock-Howard R, Wilson J, Witiw C, Cho N, Squair J, Aureli V, James N, Bole-Feysot L, Dewany I, Hankov N, Baud L, Leonhartsberger A, Sveistyte K, Skinnider M, Gautier M, Galan K, Goubran M, Ravier J, Merlos F, Batti L, Pagès S, Bérard N, Intering N, Varescon C, Carda S, Bartholdi K, Hutson T, Kathe C, Hodara M, Anderson M, Draganski B, Demesmaeker R, Asboth L, Barraud Q, Bloch J, Courtine G, Christie SD, Greene R, Nadi M, Alant J, Barry S, Glennie A, Oxner B, Weise L, Julien L, Lownie C, Dvorak MF, Öner CFC, Dandurand C, Joeris A, Schnake K, Phillips M, Vaccaro AR, Bransford R, Popescu EC, El-Sharkawi M, Rajasekaran S, Benneker LM, Schroeder GD, Tee JW, France J, Paquet J, Allen R, Lavelle WF, Vialle E, Dea N, Dionne A, Magnuson D, Richard-Denis A, Petit Y, Bernard F, Barthélémy D, Mac-Thiong JM, Grassner L, Garcia-Ovejero D, Beyerer E, Mach O, Leister I, Maier D, Aigner L, Arevalo-Martin A, MacLean MA, Charles A, Georgiopoulos M, Charest-Morin R, Goodwin R, Weber M, Brouillard E, Richard-Denis A, Dionne A, Laassassy I, Khoueir P, Bourassa-Moreau É, Maurais G, Mac-Thiong JM, Zaldivar-Jolissaint JF, Dea N, Brown AA, So K, Manouchehri N, Webster M, Ethridge J, Warner A, Billingsley A, Newsome R, Bale K, Yung A, Seneviratne M, Cheng J, Wang J, Basnayake S, Streijger F, Heran M, Kozlowski P, Kwon BK, Golan JD, Elkaim LM, Alrashidi Q, Georgiopoulos M, Lasry OJ, Bednar DA, Love A, Nedaie S, Gandhi P, Amin PC, Raj A, McIntosh G, Neilsen CJ, Swamy G, Rampersaud R (On behalf of CSORN investigators), Vandewint A, Rampersaud YR, Hebert J, Bigney E, Manson N, Attabib N, Small C, Richardson E, Kearney J, Abraham E, Rampersaud R, Raj A, Marathe N, McIntosh G, Dhiman M, Bader TJ, Hart D, Swamy G, Duncan N, Dhiman M, Bader TJ, Ponjevic D, Matyas JR, Hart D, Swamy G, Duncan N, O'Brien CP, Hebert J, Bigney E, Kearney J, Richardson E, Abraham E, Manson N, Attabib N, Small C, LaRochelle L, Rivas G, Lawrence J, Ravinsky R, Kim D, Dermott J, Mitani A, Doria A, Howard A, Lebel D, Dermott JA, Switzer LS, Kim DJ, Lebel DE, Montpetit C, Vaillancourt N, Rosenstein B, Fortin M, Nadler E, Dermott J, Kim D, Lebel DE, Wolfe D, Rosenstein B, Fortin M, Wolfe D, Dover G, Boily M, Fortin M, Shakil H, Malhotra AK, Badhiwala JH, Karthikeyan V, He Y, Fehlings MG, Sahgal A, Dea N, Kiss A, Witiw CD, Redelmeier DR, Wilson JR, Caceres MP, Freire V, Shen J, Al-Shakfa F, Ahmed O, Wang Z, Kwan WC, Zuckerman SL, Fisher CG, Laufer I, Chou D, O'Toole JE, Schultheiss M, Weber MH, Sciubba DM, Pahuta M, Shin JH, Fehlings MG, Versteeg A, Goodwin ML, Boriani S, Bettegowda C, Lazary A, Gasbarrini A, Reynolds JJ, Verlaan JJ, Sahgal A, Gokaslan ZL, Rhines LD, Dea N, Truong VT, Dang TK, Osman G, Al-Shakfa F, Boule D, Shen J, Wang Z, Rizkallah M, Boubez G, Shen J, Phan P, Alshakfa F, Boule D, Belguendouz C, Kafi R, Yuh SJ, Shedid D, Wang Z, Wang Z, Shen J, Boubez G, Alshakfa F, Boulé D, Belguendouz C, Kafi R, Phan P, Shedid D, Yuh SJ, Rizkallah M, Silva YGMD, Weber L, Leão F, Essa A, Malhotra AK, Shakil H, Byrne J, Badhiwala J, Nathens AB, Azad TD, Yuan E, He Y, Jack AS, Mathieu F, Wilson JR, Witiw CD, Craig M, Guenther N, Valosek J, Bouthillier M, Enamundram NK, Rotem-Kohavi N, Humphreys S, Christie S, Fehlings M, Kwon B, Mac-Thiong JM, Phan P, Paquet J, Guay-Paquet M, Cohen-Adad J, Cadotte D, Dionne A, Mac-Thiong JM, Hong H, Kurban D, Xu J, Barthélémy D, Christie S, Fourney D, Linassi G, Sanchez AL, Paquet J, Sreenivasan V, Townson A, Tsai EC, Richard-Denis A, Kwan WC, Laghaei P, Kahlon H, Ailon T, Charest-Morin R, Dandurand C, Paquette S, Dea N, Street J, Fisher CG, Dvorak MF, Kwon BK, Thibault J, Dionne A, Al-Sofyani M, Pelletier-Roy R, Richard-Denis A, Bourassa-Moreau É, Mac-Thiong JM, Bouthillier M, Valošek J, Enamundram NK, Guay-Paquet M, Guenther N, Rotem-Kohavi N, Humphreys S, Christie S, Fehlings M, Kwon BK, Mac-Thiong JM, Phan P, Cadotte D, Cohen-Adad J, Reda L, Kennedy C, Stefaniuk S, Eftekhar P, Robinson L, Craven C, Dengler J, Kennedy C, Reda L, Stefaniuk S, Eftekhar P, Robinson L, Craven C, Dengler J, Roukerd MR, Patel M, Tsai E, Galuta A, Jagadeesan S, Sandarage RV, Phan P, Michalowski W, Van Woensel W, Vig K, Kazley J, Arain A, Rivas G, Ravinsky R, Lawrence J, Gupta S, Patel J, Turkstra I, Pustovetov K, Yang V, Jacobs WB, Mariscal G, Witiw CD, Harrop JS, Essa A, Witiw CD, Mariscal G, Jacobs WB, Harrop JS, Essa A, Du JT, Cherry A, Kumar R, Jaber N, Fehlings M, Yee A, Dukkipati ST, Driscoll M, Byers E, Brown JL, Gallagher M, Sugar J, Rockall S, Hektner J, Donia S, Chernesky J, Noonan VK, Varga AA, Slomp F, Thiessen E, Lastivnyak N, Maclean LS, Ritchie V, Hockley A, Weise LM, Potvin C, Flynn P, Christie S, Turkstra I, Oppermann B, Oppermann M, Gupta S, Patel J, Pustovetov K, Lee K, Chen C, Rastgarjazi M, Yang V, Hardy S, Strantzas S, Anthony A, Dermott J, Vandenberk M, Hassan S, Lebel D, Silva YGMD, LaRue B, Couture J, Pimenta N, Blanchard J, Chenevert A, Goulet J, Greene R, Christie SD, Hall A, Etchegary H, Althagafi A, Han J, Greene R, Christie S, Pickett G, Witiw C, Harrop J, Jacobs WB, Mariscal G, Essa A, Jacobs WB, Mariscal G, Witiw C, Harrop JS, Essa A, Lasswell T, Rasoulinejad P, Hu R, Bailey C, Siddiqi F, Hamdoon A, Soliman MA, Maraj J, Jhawar D, Jhawar B, Schuler KA, Orosz LD, Yamout T, Allen BJ, Lerebo WT, Roy RT, Schuler TC, Good CR, Haines CM, Jazini E, Ost KJ, Al-Shawwa A, Anderson D, Evaniew N, Jacobs BW, Lewkonia P, Nicholls F, Salo PT, Thomas KC, Yang M, Cadotte D, Sarraj M, Rajapaksege N, Dea N, Evaniew N, McIntosh G, Pahuta M, Alharbi HN, Skaik K, Wai EK, Kingwell S, Stratton A, Tsai E, Phan PTN, Wang Z, Investigators C, Zaldivar-Jolissaint JF, Gustafson S, Polyzois I, Gascoyne T, Goytan M, Bednar DA, Sarra M, Rocos B, Sardi JP, Charalampidis A, Gum J, Lewis SJ, Ghag R, Kirk S, Shirley O, Bone J, Morrison A, Miyanji F, Parekh A, Sanders E, Birk M, Nicholls F, Smit K, Livock H, Romeo J, Jarvis J, Tice A, Frank S, Labelle H, Parent S, Barchi S, Joncas J, Mac-Thiong JM, Thibault J, Joncas J, Barchi S, Parent S, Beausejour M, Mac-Thiong JM, Dionne A, Mac-Thiong JM, Parent S, Shen J, Joncas J, Barchi S, Labelle H, Birk MS, Nicholls F, Pelletier-Roy R, Sanders E, Lewis S, Aljamaan Y, Lenke LG, Smith J, Sardar Z, Mullaj E, Lebel D, Dermott J, Bath N, Mathias K, Kattail D, Zohar A, Loomans J, Pellise F, Smith JS, Kato S, Sardar Z, Lenke L, Lewis SJ, Bader TJ, Dhiman M, Hart D, Duncan N, Salo P, Swamy G, Lewis SJ, Lawrence PL, Smith J, Pellise F, Sardar Z, Lawrence PL, Lewis SJ, Smith J, Pellise F, Sardar Z, Levett JJ, Alnasser A, Barak U, Elkaim LM, Hoang TS, Alotaibi NM, Guha D, Moss IL, Weil AG, Weber MH, de Muelenaere P, Parvez K, Sun J, Iorio OC, Rosenstein B, Naghdi N, Fortin M, Manocchio F, Ankory R, Stallwood L, Ahn H, Mahdi H, Naeem A, Jhawar D, Moradi M, Jhawar B, Qiu S, Surendran V, Shi V, Cheung E, Ngana S, Qureshi MA, Sharma SV, Pahuta M, and Guha D

Published
2024
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109. Patient, clinical, surgical, and institutional factors associated with length of stay in scheduled degenerative thoracolumbar spine surgery: National Multicenter Cohort Analysis from the Canadian Spine Outcomes and Research Network.

Author

Dandurand C, Mashayekhi MS, McIntosh G, Street JT, Fisher CG, Finkelstein J, Abraham E, Paquet J, Hall H, Wai E, Fourney DR, Bailey CS, Christie SD, Soroceanu A, Johnson M, Kelly A, Marion TE, Nataraj A, Santaguida C, Warren D, Hogan TG, Manson N, Phan P, Ahn H, Rampersaud YR, Blanchard J, Thomas K, Dea N, and Charest-Morin R

Subjects
Humans, Retrospective Studies, Length of Stay, Treatment Outcome, Canada epidemiology, Lumbar Vertebrae surgery, Spinal Fusion methods
Abstract

Objective: Length of stay (LOS) is a contributor to costs and resource utilization. The primary goal of this study was to identify patient, clinical, surgical, and institutional variables that influence LOS after elective surgery for thoracolumbar degenerative pathology. The secondary objective was to examine variability in LOS and institutional strategies used to decrease LOS., Methods: This is a retrospective study of prospectively collected data from a multicentric cohort enrolled in the Canadian Spine Outcomes and Research Network (CSORN) between January 2015 and October 2020 who underwent elective thoracolumbar surgery (discectomy [1 or 2 levels], laminectomy [1 or 2 levels], and posterior instrumented fusion [up to 5 levels]). Prolonged LOS was defined as LOS greater than the median. Logistic regression models were used to determine factors associated with prolonged LOS for each procedure. A survey was sent to the principal investigators of the participating healthcare institutions to understand institutional practices that are used to decrease LOS., Results: A total of 3700 patients were included (967 discectomies, 1094 laminectomies, and 1639 fusions). The median LOSs for discectomy, laminectomy, and fusion were 0.0 (IQR 1.0), 1.0 (IQR 2.0), and 4.0 (IQR 2.0) days, respectively. On multivariable analysis, predictors of prolonged LOS for discectomy were having more leg pain, higher Oswestry Disability Index (ODI) scores, symptom duration more than 2 years, having undergone an open procedure, occurrence of an adverse event (AE), and treatment at an institution without protocols to reduce LOS (p < 0.05). Predictors of prolonged LOS for laminectomy were increased age, living alone, higher ODI scores, higher BMI, open procedures, longer operative time, AEs, and treatment at an institution without protocols to reduce LOS (p < 0.05). For posterior instrumented fusion, predictors of prolonged LOS were older age, living alone, more comorbidities, higher ODI scores, longer operative time, AEs, and treatment at an institution without protocols to reduce LOS (p < 0.05). The laminectomy group had the largest variability in LOS (SD 4.4 days, range 0-133 days). Three hundred fifty-four patients (22%) had an LOS above the 75th percentile. Ten institutions (53%) had either Enhanced Recovery After Surgery or standardized protocols in place., Conclusions: Among the factors identified in this study, worse baseline ODI scores, experiencing AEs, and treatment at an institution without protocols aimed at reducing LOS were predictive of prolonged LOS in all surgical groups. The laminectomy group had the largest variability in LOS.

Published
2022
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110. Time to return to work after elective lumbar spine surgery.

Author

Singh S, Ailon T, McIntosh G, Dea N, Paquet J, Abraham E, Bailey CS, Weber MH, Johnson MG, Nataraj A, Glennie RA, Attabib N, Kelly A, Hall H, Rampersaud YR, Manson N, Phan P, Thomas K, Fisher CG, and Charest-Morin R

Abstract

Objective: Time to return to work (RTW) after elective lumbar spine surgery is variable and dependent on many factors including patient, work-related, and surgical factors. The primary objective of this study was to describe the time and rate of RTW after elective lumbar spine surgery. Secondary objectives were to determine predictors of early RTW (< 90 days) and no RTW in this population., Methods: A retrospective analysis of prospectively collected data from the multicenter Canadian Spine Outcomes and Research Network (CSORN) surgical registry was performed to identify patients who were employed and underwent elective 1- or 2-level discectomy, laminectomy, and/or fusion procedures between January 2015 and December 2019. The percentage of patients who returned to work and the time to RTW postoperatively were calculated. Predictors of early RTW and not returning to work were determined using a multivariable Cox regression model and a multivariable logistic regression model, respectively., Results: Of the 1805 employed patients included in this analysis, 71% returned to work at a median of 61 days. The median RTW after a discectomy, laminectomy, or fusion procedure was 51, 46, and 90 days, respectively. Predictors of early RTW included male gender, higher education level (high school or above), higher preoperative Physical Component Summary score, working preoperatively, a nonfusion procedure, and surgery in a western Canadian province (p < 0.05). Patients who were working preoperatively were twice as likely to RTW within 90 days (HR 1.984, 95% CI 1.680-2.344, p < 0.001) than those who were employed but not working. Predictors of not returning to work included symptoms lasting more than 2 years, an increased number of comorbidities, an education level below high school, and an active workers' compensation claim (p < 0.05). There were fourfold odds of not returning to work for patients who had not been working preoperatively (OR 4.076, 95% CI 3.087-5.383, p < 0.001)., Conclusions: In the Canadian population, 71% of a preoperatively employed segment returned to work after 1- or 2-level lumbar spine surgery. Most patients who undergo a nonfusion procedure RTW after 6 to 8 weeks, whereas patients undergoing a fusion procedure RTW at 12 weeks. Working preoperatively significantly increased the likelihood of early RTW.

Published
2021
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