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Purpose: Evaluate visual outcomes following implantation of a non-diffractive extended deapth of focus (EDOF) intraocular lens (IOL) in patients with early dry age-related macular degeneration (AMD)., Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India., Design: Prospective, interventional series., Methods: Patients undergoing cataract surgery with the EDOF Acrysof Vivity IOL and having early dry AMD were included. Primary outcome measures were monocular unaided and corrected distance visual acuity (UDVA, CDVA) 3 months postoperatively. Secondary outcome measures were: monocular unaided and distance corrected intermediate (UIVA, DCIVA) (66cm) and near (UNVA, DCNVA) (40cm) visual acuity as well as mesopic contrast sensitivity (CS)., Results: 40 eyes (40 patients) with a mean age of 68.5 + 8.38 (standard deviation, SD) years were included. UDVA and CDVA at 3 months follow up were 0.12 + 0.07 and 0.10 + 0.10 (SD) LogMAR. UIVA, DCIVA were 0.25 + 0.09, 0.12 + 0.09 LogMAR. UNVA, DCNVA were 0.23 + 0.10, 0.19 + 0.15 LogMAR. Mesopic CS values without glare were 1.50 + 0.10, 1.69 + 0.26, 1.40 + 0.30 and 0.84 + 0.5 units at 3, 6, 12 and 18 cycles per degree (CPD). Mesopic CS with glare was 1.53 + 0.16, 1.63 + 0.21, 1.21 + 0.45 and 0.75 + 0.42 units., Conclusion: The Acrysof Vivity IOL gives very good distance visual acuity with improved intermediate and near visual acuity without significant compromise in contrast sensitivity in eyes with early dry AMD., (Copyright © 2025 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.)

Posterior capsules of pediatric eyes with lens disorders have complex morphological variations with differing etiologies and visual prognoses. We describe a unique case of intraoperative posterior capsule flutter in an eye of a child undergoing cataract surgery, which we interpret as a possible expression of posterior lentiglobus., (Copyright (c) 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.)

Post-operative capsular opacification is a multifactorial physiological consequence of cataract surgery. Opacification involving the central posterior capsule has a significant impact on high and low contrast acuity and low contrast sensitivity. The assessment of Posterior Capsule Opacification (PCO) on cadaver eyes, experimental studies, culture models and in clinical studies has provided an understanding of its pathogenesis. The proliferation, migration and abnormal differentiation of residual lens epithelial cells and fibers in the capsular bag have been implicated in the pathogenesis of PCO. The incidence and severity of PCO correlates to the meticulous use of surgical techniques, IOL optic edge designs and IOL materials. This article summarizes the clinical studies with recommendations for retarding the development of central PCO. It discusses experiments with pharmacological agents broadly categorized as anti-inflammatory, immuno-modulating, antiproliferative, antiadhering, antitransdifferentiating agents for the prevention of PCO. These studies will remain critical for future endeavors undertaken for eradication of PCO.