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Copyright of China Sciencepaper is the property of China Sciencepaper and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Dalian University of Technology / Dalian Ligong Daxue Xuebao is the property of Journal of Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Jiaotong University (Medical Science) is the property of Journal of Shanghai Jiaotong University (Medical Science) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Ｏｂｊｅｃｔｉｖｅ　Ｔｏ ａｎａｌｙｚｅ ｔｈｅ ｃｌｉｎｉｃｏｐａｔｈｏｌｏｇｉｃａｌ ｆｅａｔｕｒｅｓ ａｎｄ ｐｒｏｇｎｏｓｉｓ ｏｆ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ． Ｍｅｔｈｏｄｓ　Ｔｈｅ ｃｌｉｎｉｃｏｐａｔｈｏｌｏｇｉｃａｌ ａｎｄ ｆｏｌｌｏｗ⁃ｕｐ ｄａｔａ ｏｆ ９８ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ ｗｈｏ ｕｎｄｅｒｗｅｎｔ Ｒ０ ｒｅｓｅｃｔｉｏｎ ｆｒｏｍ Ｊａｎｕａｒｙ ２００９ ｔｏ Ｄｅｃｅｍｂｅｒ ２０１３ ｗｅｒｅ ａｎａｌｙｚｅｄ ｒｅｔｒｏｓｐｅｃｔｉｖｅｌｙ． Ｒｅｓｕｌｔｓ　Ａｌｌ ｏｆ ｔｈｅ ｐａｔｉｅｎｔｓ ｗｅｒｅ ｆｏｌｌｏｗｅｄ ｕｐ． Ｔｈｅｉｒ ｐｏｓｔｏｐｅｒａｔｉｖｅ １⁃ｙｅａｒ， ３⁃ｙｅａｒ ａｎｄ ５⁃ｙｅａｒ ｏｖｅｒａｌｌ ｓｕｒｖｉｖａｌ ｒａｔｅｓ ｗｅｒｅ ９９．０％， ９１．７％， ａｎｄ ７６．３％， ｒｅｓｐｅｃｔｉｖｅｌｙ． Ｔｈｅｉｒ ｐｏｓｔｏｐｅｒａｔｉｖｅ ｍｅｄｉａｎ ｏｖｅｒａｌｌ ｓｕｒｖｉｖａｌ （ＯＳ） ｐｅｒｉｏｄ ｗａｓ ５２ ｍｏｎｔｈｓ． Ｔｈｅ ｐｏｓｔｏｐｅｒａｔｉｖｅ ｐｒｏｇｒｅｓｓｉｏｎ⁃ｆｒｅｅ ｓｕｒｖｉｖａｌ ｒａｔｅｓ ｗｅｒｅ ８６．７％， ６６．２％ ａｎｄ ５５．０％， ｒｅｓｐｅｃｔｉｖｅｌｙ， ａｎｄ ｔｈｅ ｍｅｄｉａｎ ｐｒｏｇｒｅｓｓｉｏｎ⁃ｆｒｅｅ ｓｕｒｖｉｖａｌ （ＰＦＳ） ｐｅｒｉｏｄ ｗａｓ ４３．５ ｍｏｎｔｈｓ． Ｔｈｅ ｕｎｉｖａｒｉａｔｅ ａｎａｌｙｓｉｓ ｓｈｏｗｅｄ ｔｈａｔ ｓａｔｅｌｌｉｔｅ ｎｏｄｕｌｅｓ， ｌｉｖｅｒ ｃａｐｓｕｌｅ ｉｎｖａｓｉｏｎ ａｎｄ ｐｏｓｔｏｐｅｒａｔｉｖｅ ｒｅｃｕｒｒｅｎｃｅ ｔｉｍｅ ｗｅｒｅ ａｓｓｏｃｉａｔｅｄ ｗｉｔｈ ＯＳ （Ｐ＜０．０５）， ａｎｄ ｌｏｎｇ⁃ｔｅｒｍ ｈｅａｖｙ ｄｒｉｎｋｉｎｇ， ｓａｔｅｌｌｉｔｅ ｎｏｄｕｌｅｓ ａｎｄ ｌｉｖｅｒ ｃａｐｓｕｌｅ ｉｎｖａｓｉｏｎ ｗｉｔｈ ＰＦＳ （Ｐ ＜０．０５）． Ｔｈｅ ｍｕｌｔｉｖａｒｉａｔｅ ａｎａｌｙｓｉｓ ｉｎｄｉｃａｔｅｄ ｔｈａｔ ｌｏｎｇ⁃ｔｅｒｍ ｈｅａｖｙ ｄｒｉｎｋｉｎｇ ｗａｓ ａｎ ｉｎｄｅｐｅｎｄｅｎｔ ｆａｃｔｏｒ ｉｎｆｌｕｅｎｃｉｎｇ ｔｈｅ ｐｒｏｇｒｅｓｓｉｏｎ⁃ｆｒｅｅ ｓｕｒｖｉｖａｌ ｐｅｒｉｏｄ ｏｆ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ （Ｐ ＝０．００３） ａｎｄ ｐｏｓｔｏｐｅｒａｔｉｖｅ ｒｅｃｕｒｒｅｎｃｅ ｔｉｍｅ ａｎｄ ｌｉｖｅｒ ｃａｐｓｕｌｅ ｉｎｖａｓｉｏｎ ｗｅｒｅ ｉｎｄｅｐｅｎｄｅｎｔ ｆａｃｔｏｒｓ ａｆｆｅｃｔｉｎｇ ｔｈｅｉｒ ｏｖｅｒａｌｌ ｓｕｒｖｉｖａｌ ｐｅｒｉｏｄ （Ｐ ＜ ０． ０５）． Ｃｏｎｃｌｕｓｉｏｎｓ 　Ｔｈｅ ｔｒｅａｔｍｅｎｔ ｏｆ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ ｓｔｉｌｌ ｃｏｎｃｅｎｔｒａｔｅｓ ｏｎ ｔｈｅ ａｃｔｉｖｅ ｔｒｅａｔｍｅｎｔ ｏｆ ｓｕｒｇｅｒｙ． Ｉｔ ｉｓ ｂｅｎｅｆｉｃｉａｌ ｔｏ ｐａｔｉｅｎｔｓ ｔｏ ｍｉｎｉｍｉｚｅ ｔｈｅ ｒｅｓｅｃｔｉｏｎ ｓｃｏｐｅ ｏｆ ｎｏｒｍａｌ ｌｉｖｅｒ ｕｎｄｅｒ ｔｈｅ ｐｒｅｍｉｓｅ ｏｆ Ｒ０ ｒｅｍｏｖａｌ ｏｆ ｔｕｍｏｒ． Ｐｏｓｔｏｐｅｒａｔｉｖｅ ｒｅｃｕｒｒｅｎｃｅ ｔｉｍｅ ｏｆ ≤２ ｙｅａｒｓ ｓｕｇｇｅｓｔｓ ｐｏｏｒ ｐｒｏｇｎｏｓｉｓ ｏｆ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ． Ｌｏｎｇ⁃ｔｅｒｍ ｈｅａｖｙ ｄｒｉｎｋｉｎｇ ｃａｎ ａｃｃｅｌｅｒａｔｅ ｔｈｅ ｒｅｃｕｒｒｅｎｃｅ ｏｆ ｓｍａｌｌ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ． [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的观察围绝经期子宫内膜息肉(endometrial polyps,EP)组织中细胞跨膜Notch配体4(DLL4)、基质金属蛋白酶9(MMP9)的表达变化,并探讨其意义。方法围绝经期EP患者50例(EP组),其中绝经前后EP患者各25例,均未接受激素治疗,术中留取患者EP组织。同期选取围绝经期因子宫肌瘤或子宫脱垂接受子宫切除术的患者50例(对照组),其中绝经前后各25例,留取患者正常子宫内膜组织。采用免疫组化染色方法检测EP组患者EP组织及对照组患者正常子宫内膜组织中的DLL4和MMP9。结果 EP组25例绝经前患者EP组织中DLL4、MMP9蛋白阳性表达率分别为88%、84%,对照组25例绝经前患者正常子宫内膜组织中DLL4、MMP9蛋白阳性表达率分别为28%、32%,两者相比,P均<0. 01。EP组25例绝经后患者EP组织中DLL4、MMP9蛋白阳性表达率分别为80%、76%,对照组25例绝经后患者正常子宫内膜组织中DLL4、MMP9蛋白阳性表达率分别为36%、40%,两者相比,P均<0. 05。结论围绝经期EP组织中DLL4和MMP9呈高表达状态,DLL4、MMP9可能与EP的发生发展有关。 [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives To enhance the diagnosis of cervical epithelial neoplasia and cervical cancer at the early stage and to prevent cervical invasive carcinoma by analyzing the cervical/vaginal cytology or histopathologic results of Atypical squamous cells of undetermined significance (ASCUS). Methods From January 2014 to June 2015， a total of 4579 cases were selected in the census of gynecological diseases in Qiannan Hospital. TBS classification (the bethesda system) showed that 164 cases of ASCUS or above were found using cervical/vaginal cytology with live tissue under colposcopy．Results Among 164 cases， 75 was cervical intraepithelial neoplasia level 3 (CINIII) accounting for 54.7%. Sixty-three cases of ASCUS and 16 of CINII or above were found among patients at the age of 39 or younger (25.4%). A hundred and one cases of ASCUS and 59 of CINII or above were found among women older than 40 (58.41%). Among patients with liquid-based cervical cytology positive， those older than 40 had higher risk. Liquid-based cervical cytology examination was divided into 5 levels. Spearman rank correlation analysis was applied with correlation coefficient (r = 1) and positive correlation was shown (P = 0.000， P<0.01). The difference was statistically significant. The higher level of liquid-based cervical cytology examination level was required， the higher risk of cervical cancer was seen among women. Conclusion The use of liquid-based cervical cytology examination can help grassroots doctors improve CIN diagnosis rate and prevent cervical invasive carcinoma among women in the countryside. [ABSTRACT FROM AUTHOR]

Objective To investigate the prognostic factors for patients with intrahepatic cholangiocarcinoma after surgical resection. Methods The clinicopathological and follow-up data of 123 patients with intrahepatic cholangiocarcinoma who underwent surgical resection in Cancer Hospital, Chinese Academy of Medical Sciences between January 1999 and June 2015 were collected and reviewed, and their survival and prognosis were analyzed with the Kaplan-Meier method and Cox regression model. Results The median follow-up time was 22 months and median recurrence-free survival time was 8.97 months. The 1-, 2- and 3-year recurrence rates were 58.6%, 68.9% and 76.5%, respectively. Cox multivariate regression analysis showed that preoperative rise in CEA, lymph node metastasis, multiple lesions, extrahepatic invasion, and combination of tumor necrosis were significant adverse prognostic factors affecting the postoperative recurrence-free survival in patients with intrahepatic cholangiocarcinoma after surgical resection (P<0.05 for all). The median overall survival time was 21.17 months, and the 1-, 3- and 5-year overall survival rates were 76.6%, 33.2% and 26.1%, respectively. The Cox multivariate regression analysis showed that preoperative rise in CEA, lymph node metastasis, multiple lesions, and extrahepatic invasion were significant adverse prognostic factors affecting the postoperative overall survival in patients with intrahepatic cholangiocarcinoma after surgical resection(P<0.05 for all). Conclusion Preoperative rise in CEA, lymph node metastasis, multiple lesions and extrahepatic invasion are significant adverse prognostic factors for patients with intrahepatic cholangiocarcinoma after surgical resection. [ABSTRACT FROM AUTHOR]

Objective: To analyze the risk factors of recurrence for patients with traumatic vertebral fractures who had taken the vertebroplasty surgery. Methods: 113cases (131 vertebrae) with recurrent vertebral fracture were selected from our hospital treated by Percutaneous vertebroplasty（PVP）or Percutaneous kyphoplasty (PKP). According to the different treatment methods (PVP or PKP) and recurrence site of the fractures (surgery vertebrae or non-surgery vertebrae), they were divided into group A1, A2, B1, B2, C1, C2. Another 56 cases without refracture after operation was selected as control (D group). The possible risk factors of recurrent fractures were recorded and analyzed in each refractured group after compared with group D. Results: There was no statistical significance between the patients' height, weight and age (P>0.05), and the volume of bone cement injected was statistically significant (P<0.05). There were statistically significant differences in the cement penetration of intervertebral discs and the use of anti-osteoporosis drug (P<0. 05). There were statistically significant differences in the concentrations of 25- (OH) D between the refracture patients and group D. The pelvic cement penetration, lower 25 - (OH) D concentration and without the use of anti-osteoporosis drugs were the risk factors of recurrence of vertebral fractures (P<0.05). Conclusions: The pelvic cement penetration, lower 25 - (OH) D concentration and without the use of anti-osteoporosis drugs are the risk factors of postoperative recurrence of vertebral fractures. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To compare the clinical effect of efficacy of minimally invasive stabilization through intermuscular approach and percutaneous pedicle screw fixation in the treatment of thoracolumbar fractures. Methods: 120 cases with thoracolumbar fractures who were treated in our hospital from January 2010 to December 2014 were selected and randomly divided into the minimally invasive group and the open surgery group. Then the operation time, blood loss, hospitalization and postoperative recovery of the two groups were observed and compared. Results: There was no statistically significant differences in the operation time between the two groups (P>0.05). Compared with the open surgery group, the operation time and hospitalization of the minimally invasive group were shorter (P<0.05). Compared with before treatment, the Cobb angle and the vertebral height of patients in both groups were better after the operation (P<0.05); There was no statistically significant differences in the Cobb angle and the vertebral height between the two groups (P>0.05). Compared with before treatment, the JOA scores in both groups after the operation were reduced (P<0.05), but there was no statistically significant differences in the JOA score between the two groups (P>0.05). Conclusion: Minimally invasive stabilization through intermuscular approach and percutaneous pedicle screw fixation could both better fix the thoracolumbar fractures, and the minimally invasive stabilization through intermuscular approach was better with less trauma and blood loss, faster recovery and short hospitalization, which was worth of clinical application. [ABSTRACT FROM AUTHOR]

Copyright of Electric Machines & Control / Dianji Yu Kongzhi Xuebao is the property of Electric Machines & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的观察淋巴瘤组织中的生存素(survivin)蛋白、细胞周期蛋白(Cyclin)D1蛋白的表达变化。方法采用MaxvisionTM/HRP免疫组织化学染色法对61例淋巴瘤患者的病变淋巴瘤组织和28例淋巴结反应性增生患者的病变淋巴结组织中的survivin蛋白、Cyclin D1蛋白进行检测。结果 61例淋巴瘤患者的病变淋巴瘤组织中survivin蛋白阳性表达率为57.38%(35/61)、28例淋巴结反应性增生患者的病变淋巴结组织阳性表达率为21.43%(6/28),两者相比,P<0.01。61例淋巴瘤患者的病变淋巴瘤组织Cyclin D1蛋白阳性表达率为39.34%(24/61)、28例淋巴结反应性增生患者的病变淋巴结组织阳性表达率为0(0/28),两者相比,P<0.01。survivin蛋白的阳性表达与淋巴瘤患者血清乳酸脱氢酶水平升高、临床分期高及恶性程度高有关(P均<0.05)。Cyclin D1蛋白的阳性表达与淋巴瘤患者B组症状、临床分期高及恶性程度高有关(P均<0.05)。在61例淋巴瘤患者中,survivin蛋白与Cyclin D1蛋白的表达呈正相关(r=0.287,P<0.05)。结论 survivin蛋白与Cyclin D1蛋白在淋巴瘤组织中均呈高表达,两者有可能成为淋巴瘤诊断的标志物,并可协助判断淋巴瘤的恶性程度,二者在淋巴瘤的发生、发展过程中可能发挥协同作用。 [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的检测恶性淋巴瘤组织中nm23、Survivin蛋白表达情况,并分析其临床意义。方法选择58例恶性淋巴瘤患者和27例反应增生性淋巴结炎患者,应用免疫组化染色法检测恶性淋巴瘤组织(观察组)和反应增生性淋巴结组织(对照组)中nm23、Survivin蛋白表达情况。结果观察组nm23、Survivin呈过表达,对照组nm23、Survivin呈低表达(P均<0.01)。nm23过表达与B组症状、临床分期高、恶性程度高、结外累计部位数多有关(P均<0.05),Survivin过表达与临床分期高、恶性程度高及乳酸脱氢酶增高有关(P均<0.05)。nm23与Survivin表达呈正相关(r=0.323,P<0.05)。结论恶性淋巴瘤组织中nm23蛋白与Survivin蛋白均过表达,且nm23蛋白、Survivin蛋白过表达与恶性淋巴瘤的发生、发展过程密切相关。 [ABSTRACT FROM AUTHOR]

目的探讨乙肝肝硬化门静脉高压患者经颈静脉肝内门体分流术（TIPS)前后门静脉、肝静脉血清CX-C15水平变化及其与患者预后的关系。方法选择行TIPS的乙肝肝硬化门静脉高压患者80例，术后中位生存时 间为293天，其中备293天者37例，<293天者43例。分析80例患者术前及术后14天相关实验室检查资料，如 0父05、胆红素、胆碱酯酶、内蛋白、ALT, AST-γ 将氨酰转肽酶、国际标准化比率、血肌酐、尿素鉍、血清钠、PLT门静 脉压力、中心静脉压力、门静脉血流速度，比较生存时间為293天者与<293天者上述指标变化，并筛选影响患者预 后的危险因素。结果80例患者术后门静脉和肝静脉血清CXCL9水平均低于术前(P均<0. 05)。单因素分析发 现，生存时间為293天者与<293天者术前门静脉和肝静脉血清CXCL9、Na+、血肌酐、尿素M、胆红素水平以及术后 门静脉压比较P均<0.05,其他相关实验室检查资料比较P均>0. 05。多因素Cox回归分析发现，术前门静脉血 清0乂05水平是患者预后的独立影响因素（OR=0.261，95%(：/为0.132~ 0.524，户<0.0丨），术前门静脉血清 CXCL9彡400 pg/mL者与<400 Pg/mL者平均生存时间分别为113、941天，二者比较P <0.0U结论乙肝肝硬化 门静脉高压患者TIPS术后门静脉、肝静脉血清CXCLS水平明显降低,术前门静脉血清CXCLS水平>400 pg/mL者 预后较差。 [ABSTRACT FROM AUTHOR]

目的观察临床早期宫颈癌患者接受保留盆腔自主神经广泛性子宫切除术治疗后膀胱功能及术后性生 活质量恢复情况。方法选择FIGO分期为I a2期、I b1期、II a1期并手术治疗宫颈癌患者50例，根据手术方式 不同分为两组。其中保留盆腔自主神经广泛性子宫切除术（NSRH)组20例，广泛性子宫切除术（RH)组30例。观 察两种不同术式患者的手术时间、术中出血、淋巴结清扫数目、尿管留置时间、残余尿量及术后1年性生活质量的 变化。结果术后病理证实,两组手术切缘（阴道切缘、宫旁切缘）未见癌灶残留。两组手术时间、术中出血量、淋 巴结清扫数目比较差异无统计学意义（P均>0.05 )。与RH组比较，NSRH组术后留置尿管时间短、术后7 d膀胱 残余尿量少（P均<0.05)。术前两组性功能障碍构成比无统计学差异（P >0. 05);术后1年NSRH组性功能障碍 构成比42%，RH组性功能障碍构成比79.6% ,两组比较差异有统计学意义（P<0. 05)。结论 早期宫颈癌患者 行NSRH治疗术后膀胱功能恢复快，且对患者术后性生活质量影响小。 [ABSTRACT FROM AUTHOR]

Objective To investigate the changes of blood pressure, plasma renin activity (PRA) and angiotensin II (Aug II ) after operative treatment in the patients with upper urinary stones caused hypertension. Methods A total of 5 1 cases of upper urinary stones treated by different operative treatment methods (percutaneous nephroseope lithotripsy, extracorporeal shock wave lithotripsy, ureteroscopy holmium laser lithotripsy, ureteral incision nephrolithotomy) in the urologieal surgical department of our hospital from July 2014 to October2015 were selected, Hie blood pressure, venous blood PKA and Aug II levels were compared before and after treatment (before operation and on postoperative 1,2,3 d, at postoperative I week and 1 month. The blood pressure change before treatment and after postoperative I week was compared among the patients with different obstruction time and uronephrosis degrees. The factors affecting the postoperative blood pressure recovery were analyzed. Results The blood pressure value, PHA and Aug II levels after different treatment methods in 51 cases were decreased to different degrees compared with before operation, the differences were statistically significant(P<0.05). The systolic pressure and diastolic pressure at postoperative 1 week had statistical differences among 51 patients with different obstructive time and different uronephrosis degrees, the differences were statistically significant (P<0.05);moreover the systolic blood pressure and diastolic pressure at postoperative I week in the patients with the obstructive time of 3-6 months and >6 months were higher than those in the patients with the obstructive time less than 3 months, the differences were statistically significant (P<0.05); The systolic blood pressure and diastolic pressure at postoperative 1 week in the patients moderate and severe uronephrosis were higher than those in the patients with mild uronephrosis, the differences were statistically significant P

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

为了对红花籽油产品开发提供参考,通过对相关既往研究的归纳总结，综述了红花籽油的主要营养成分、健康功效研究情况，介绍了红花籽油在其他领域的应用，并对未来的研究方向进行展望。红花籽油的营养功效成分主要有亚油酸、维生素E、植物甾醇、黄酮类化合物（主要为金合欢素）。红花籽油具有抗氧化、改善心脑血管健康、保护神经系统、改善肥胖等多种健康功效。红花籽油除食用外，在畜牧业中也具有一定的应用前景。今后应加大对红花籽油健康功效和作用机制的研究,创新红花籽油加工工艺,提高功效成分的保留率,促进红花籽油在多领域的应用。In order to provide reference for the development of safflower seed oil products, through the summary of relevant previous research, the main nutrients and health effects of safflower seed oil were reviewed, the application of safflower seed oil in other fields was introduced, and the future research direction was prospected. The main nutritional components of safflower seed oil are linoleic acid, vitamin E, phytosterols, and flavonoids (acacetin). Safflower seed oil has many health effects such as anti-oxidation, improving cardiovascular and cerebrovascular health, protecting the nervous system, and improving obesity. Safflower seed oil also has a certain application prospect in animal husbandry. In the future, the research on the health effect and mechanism of action of safflower seed oil should be increased, the processing process of safflower seed oil could be innovated, and the retention rate of effective ingredients should be improved so as to promote the application of safflower seed oil in many fields.

目的 探讨该院健康足月新生儿黄疸的高峰期及抚触对母婴同室新生儿黄疸的影响。 方法 选取2014年7月至2015年3月出生的母婴同室中200例胎龄（GA）≥37周、出生体质量（BW）2 500~4 000 g的健康足月新生儿作为研究对象。按出生时间顺序将其分为抚触组和对照组，各100例。观察两组经皮胆红素值（TcB）及排便情况。 结果 健康足月新生儿于生后第4.58天TcB达高峰；抚触组新生儿高胆红素血症发生率明显低于对照组，胎便初排时间短于对照组，差异均有统计学意义（P＜0.05）。 结论 对母婴同室的新生儿需持续监测胆红素水平，直至黄疸高峰期后及出院；抚触能有效降低新生儿胆红素水平。 [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the implementation effects of Small Private Online Course(SPOC)-based online-offline mixed teaching mode in Traditional Chinese Medicine nursing teaching. Methods Totally 593 students from Grade 2019 and Grade 2020 of the School of Nursing of Beijing University of Chinese Medicine were taught with online-offline mixed teaching mode, the scores of whom were then compared with the scores of 371 students from Grade 2017 and Grade 2018 of the school of Nursing. In addition, interview was conducted to several students who were taught with online-offline mixed teaching mode, which means the effects of online-offline mixed teaching mode were evaluated from both subjective and objective perspectives. Results Before and after the implementation of the online-offline mixed teaching mode, there were significant differences in students' total scores (P0. 05). Students believed that the online-offline mixed teaching model effectively promoted their independent learning capability, but lacked effective interaction between teachers and students. Conclusion SPOC-based online-offline mixed teaching model can effectively improve students' subjective initiative in learning and more objectively reflect the effects of students' process learning. However, there are still some problems in the implementation of this teaching model, such as teachers and students being unable to communicate in time and relying too much on students' autonomy, which need to be further improved. (目的 评价基于SPOC的线上-线下混合式教学模式的实施效果。方法 对北京中医药大学护理学院2019级和2020级二本层次593名学生实施线上-线下混合式教学, 将学生成绩与教学改革实施前的2017级和2018级二本层次371名学生的成绩进行比较分析, 并对教学改革实施后的部分学生进行访谈, 从主客观两个角度评价线上-线下混合式教学模式的效果。结果 线上-线下混合式教学模式实施前后, 学生总成绩(P＜0. 01)、形成性考核成绩(P＜0. 05)及操作考核成绩(P＜0. 01)差异有统计学意义, 终末考核成绩、平时作业成绩及实验报告成绩均无显著差异(P＞0. 05)。学生认为, 线上-线下混合式教学模式有效推动了他们自主学习, 但缺乏师生有效互动。结论 基于SPOC的线上-线下混合式教学模式, 能够有效提升学生学习的主观能动性, 并能够更加客观地反映学生的过程性学习效果, 但教学模式实施过程中仍存在师生无法及时沟通、过于依赖学生自主性等问题, 有待进一步改善。)

BACKGROUND: Personalized positioning guide plate based on three-dimensional CT data can improve the accuracy of posterior-stabilized prosthesis joint replacement, but bone structure reconstruction based on three-dimensional CT scan data ignores the thickness of distal femoral articular cartilage, which will affect the use of personalized osteotomy guide plate and the clinical effect of total knee arthroplasty. OBJECTIVE: To investigate the safety, accuracy and early clinical efficacy of three-dimensional printed screw positioning guide based on MRI and three-dimensional CT assisted medial pivot-total knee arthroplasty in the treatment of osteoarthritis. METHODS: A total of 110 patients with knee osteoarthritis admitted to Department of Orthopedics, Nanjing Hospital Affiliated to Nanjing Medical University from February 2018 to April 2019 were selected. All patients received medial pivot-total knee arthroplasty, and were randomly assigned to two groups. The 58 patients in the experimental group completed knee osteotomy with the assistance of personalized osteotomy guide plate based on MRI and three-dimensional CT. The 52 patients in the control group completed knee osteotomy with the traditional intramedullary and extramedullary positioning methods. The operation time and intraoperative blood loss of the two groups were recorded. Postoperative follow-up was conducted to review the X-ray films. KSS score of knee function and the visual analogue scale score were evaluated. RESULTS AND CONCLUSION: (1) 110 patients were followed up for 6-10 months without serious postoperative complications. (2) The operation time and intraoperative blood loss in the experimental group were less than those in the control group (P < 0.01). (3) According to the reexamination of X-ray at 1 month after surgery, the deviation between the postoperative values and the theoretical design values of hip-genus-ankle angle, coronal femoral component angle, coronal tibial component angle and sagittal tibial component angle were all smaller in the experimental group than those of the control group (P < 0.01). (4) KSS score of knee joint function in the experimental group 1, 3 and 6 months after the surgery was higher than that in the control group (P < 0.05). There was no significant difference in visual analogue scale score between the two groups (P > 0.05). (5) The results showed that the personalized osteotomy guide plate assisted internal axial knee prosthesis replacement based on MRI and three-dimensional CT could effectively improve the accuracy of prosthesis placement and shorten the operation time. The method was safe and feasible, and the early clinical effect was satisfactory. [ABSTRACT FROM AUTHOR]

China put forward the major strategy of targeted poverty alleviation in 2013, and implemented the "most stringent assessment and evaluation" system to ensure that the work of poverty alleviation is pragmatic, the process of poverty alleviation is solid and the result of poverty alleviation is real. Targeted poverty alleviation assessment is an important means to improve the effectiveness of national targeted poverty alleviation, which is of great significance to fight against poverty alleviation and promote the modernization of national governance system and governance capacity. Based on the practice of the third-party evaluation of the effectiveness of national targeted poverty alleviation, this paper discusses the differentiation law of rural poverty and its scientific cognition, summarizes the theory and technology system of national targeted poverty alleviation evaluation, and deeply analyzes the application and contribution of evaluation theory and technology in the evaluation survey over the years. Results show that the "island effect" and "marginal diminishing effect" of rural poverty, and the supply-demand structure between the government's "support" and the farmers' "poverty" are the scientific significance of implementing the effectiveness assessment of targeted poverty alleviation. They require in-depth assessment to promote rectification and effectively improve the performance of targeted poverty alleviation. The theoretical cognition and practical needs of rural poverty are the important basis for establishing assessment objectives and developing assessment plan, and plays a direct guiding role in refining the assessment indicators of antipoverty effectiveness, exploring the connotation of indicators and formulating evaluation work plans. Theoretical system of national third-party assessment on the effectiveness of targeted poverty alleviation is a comprehensive system including key technologies, supporting technologies, package support system, and big data platform. It has successfully supported the national effectiveness assessment of targeted poverty alleviation from 2016 to 2020, and has played the role of "baton", "quality inspection instrument", and "propeller", providing references for the assessment and scientific decision-making for poverty alleviation. [ABSTRACT FROM AUTHOR]