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A panel of three has reviewed a series of 100 videotape records of nasopharyngoscopy, basal fluorography and lateral fluorography made of patients being investigated for velopharyngeal incompetence. The quality of each record was assessed and estimates of movement made as a basis for comparison of the three methods. Nasopharyngoscopy and lateral fluorography provide a high proportion of material with good definition of the velopharyngeal isthmus (80%). Basal fluorography is less reliable (60%). Lateral fluorography was found to be unreliable as a measure of velopharyngeal incompetence, while estimates of movement from the other two were compatible. Basal fluorography is the procedure of choice in young children. Nasendoscopy provides good quality information more often than basal fluorography in patients over the age of eight and is markedly superior in the presence of a pharyngeal flap.

The purpose of this work was to develop an articulation test which would be discriminating in the determination of velopharyngeal incompetency in young children. From 50 words containing the /p/ and /b/ sounds, normative data for children approximately 3 1/2 years of age were collected. From the responses of these children, 25 words were selected for a base test. Validity of the test is currently being determined.

This study investigated the correlation between a physical measure of oral-nasal coupling and perceived hypernasality in speech. A modified accelerometric method was utilized to extract distributional characteristics of a ratio of the nasal accelerometric amplitude to the voice amplitude during simulated hypernasal reading by 11 female talkers. Perceived hypernasality scores for the readings were derived from a panel of 30 listeners in a paired-comparison paradigm. A correlation coefficient of .92 was obtained between the mean nasal-to-voice ratio and the perceived hypernasality scores. The results indicated that the nasal-to-voice amplitude ratio is a promising index of perceived hypernasality in speech.

Retrospectively, the medical records of patients with known velopharyngeal insufficiency (VPI) were reviewed for comments based on an unaided visual examination regarding their velopharyngeal function. These comments were compared to objective findings obtained from the cinefluorographic evaluations performed on each of the patients. A total of 68 recorded comments (47 patients) were identified and fell into four broad categories: (1) velar length, (2) depth of the nasopharynx, (3) velopharyngeal closure, and (4) velar mobility. The results revealed an agreement level of 60% between judgements made from visual examinations and cinefluorographic evaluations. This relatively poor agreement suggests that management decisions concerning VPI must include some method of objectively assessing velopharyngeal form and function during connected speech.

Respirometric quotients, indices of velopharyngeal closure, were determined from oral and nasal air volumes measured separately but simultaneously. Ten children aged 6-10 years were the subjects. The quotients were significantly lower for speech stimuli involving nasal sounds than for those involving nonnasal sounds. In contrast to the quotients obtained in previous research with children, the quotients obtained in this study were close to, but not in excess of, unity.

This study was designed as a partial test of a previously hypothesized model for a subgroup of cleft speakers who show marginal velopharyngeal competence during speech. Specifically, speakers in the model were hypothesized to show minimal but consistent nasalization of speech by several criteria. Fifty-two subjects were selected because they met one of the criteria for the model, lateral x-ray films on /s/ that showed touch closure or a small velopharyngeal opening. The subjects were then examined by the other five criteria used for defining the hypothesized model, and were found to meet, in the majority, fewer than three. These findings indicate that lateral x-ray films are not sufficient for identifying this diagnostic subgroup, if it exists. Another possible conclusion is that the model proposed is too simplistic and that cleft palate speakers with marginal velopharyngeal competency typically show more variability in speech performance than was originally implied in the model.

With the help of nasopharyngoscopy, it was possible to delineate specific morphologic changes in the palates of patients with velopharyngeal insufficiency, without an overt cleft and without the triad of symptoms of submucous cleft palate, visible through the oral cavity. Such malformations are part of the broad spectrum of the faulty midline mesodermal fusion of the palate. This anomaly is aptly called occult submucous cleft palate, because it can only be detected by viewing the functioning palate from the nasal surface. The musculus uvulae is either absent or deficient and is frequently associated with some degree of muscular diastasis that does not involve the oral surface. Like the cleft of the secondary palate, the submucous cleft palate often occurs as part of a generalized syndrome of multiple malformations.

A questionnaire designed to survey methods of assessing velopharyngeal closure and the extent of training and experience in velopharyngeal assessment was distributed to 256 randomly selected American Cleft Palate Association members. There was a 50% response rate and 94% of those responding were associated with cleft palate teams. Findings included the following: (1) the respondents rely primarily upon the use of listener judgments of spontaneous speech samples, phonological analysis, and lateral view cine/videofluoroscopy; (2) the majority spend thirty minutes or less on an average diagnostic evaluation of velopharyngeal competency; and (3) 45% feel that they are inadequately trained in assessment of velopharyngeal closure.

The purpose of this study was to describe perceptually the speech articulation, voice quality, and velopharyngeal competency of subjects with complete unilateral cleft lip and palate treated by the Zürich approach. The mean age of the 37 subjects was 10.5 years. Although only one subject had had secondary palatal management, no subject was rated as exhibiting a severe articulation or nasality problem. Subjects were rated as exhibiting adequate to marginal velopharyngeal competency 94.5 percent of the time, and the incidence of compensatory articulation errors was low. In comparison with other studies that evaluated the two-stage palatal repair, the Zürich approach appears to give the better results. The type of initial soft palate repair is probably the significant factor which contributes to the better speech of these subjects.

This study compared longitudinally perceptual ratings of articulation defectiveness, nasality, and velopharyngeal competency in 13 subjects who required secondary palatal management after age 10 with a second group. Perceptual data when examined longitudinally did not adequately discriminate between subjects who at one time achieved velopharyngeal closure but who ultimately required secondary management and those patients who needed no further treatment. A decrease in articulation scores and an increase in severity of nasality and articulation defectiveness over time indicate that patients are at risk for secondary management. Evaluation of lateral x-rays indicated that those in the group that required secondary operations demonstrated more variability in velopharyngeal closure than those in the comparison group, who required no secondary operations and that adenoidal involution did not appear to be a significant factor.

A 3-year-old child with cricopharyngeal dysfunction is reported. Swallowing difficulties, nasal regurgitation, and gagging developed at 2 months of age. Repeated aspirations and over 40 episodes of pneumonia necessitating multiple hospitalizations occurred up to 2 years of age, along with pharyngeal pooling of saliva and inability to swallow solid food. Barium was held up at the cricopharyngeal level, and a prominent esophageal impression was seen at the same level. Symptoms were completely alleviated after two esophageal dilatations by mercury dilators, and the relief persisted for the 6 months of follow-up. The diagnosis of cricopharyngeal dysfunction is discussed, and the necessity for manometric studies, in the face of often misleading radiologic appearance, is emphasized. It is suggested that early use of esophageal dilatations might prevent prolonged morbidity and afford long-term symptomatic relief.

The purpose of this study was to evaluate a levator muscle reconstruction procedure on the basis of resulting velopharyngeal competence. Ages of the patients at time of surgery ranged from 5 months to 7 years. The patients were reevaluated postoperatively. If the patients were judged to have normal nasality and no nasal emission, the procedure was considered to have yielded a satisfactory result. If hypernasality and nasal emission resulted, the patients were examined utilizing nasoendoscopy and/or videofluoroscopy. If velopharyngeal incompetence was confirmed, the operative procedure was judged to be successful. Results showed that 60 percent success was achieved. The age range which yielded the best results (73 percent satisfactory) was 37 to 60 months. The data also revealed that the more severe the cleft, the less likely this operative procedure is to produce satisfactory results. The authors recommend continued evaluation of this procedure, preferably utilizing prospective studies.

There is a paucity of respirometric quotient (RQ) data on individuals with velopharyngeal inadequacy. Paesani (1964) reported data using a technique that involved separate productions of the same task to obtain the RQ. The RQ values obtained were greater than unity, which is theoretically impossible. In the present study, respirometric quotients, the ratio of oral air volume expended to total volume expended, were obtained using separate but simultaneous productions of oral and nasal airflow. RQ values were calculated for 10 speakers with cleft palate, with and without their prosthetic appliances, and 10 normal speakers. As a group, those with cleft palate and without their appliances exhibited RQ values that were significantly lower than values obtained from the normal speakers and from speakers with the appliances in place. These findings indicated that there were no statistically significant differences in RQ values when comparing sentence repetition and counting tasks. These values were lower than those obtained for the nonnasal syllable repetition tasks, with the /mv/ syllable repetition task generally being associated with the lowest RQ value of any of the speech tasks. The correlation between RQ values and perceptual judgments was -.60, indicating that there was modest agreement between the two measures. As RQ values decreased, perceptual judgments of nasality increased.

Based upon the known association of cleft palate and middle ear disease, a study was undertaken to determine the incidence and type of middle ear pathology associated with velar anomalies exclusive of cleft palate which may produce congenital palatal pharyngeal incompetence. The range of velar anomalies encountered was subdivided into congenital palatal incompetence Type 1 (clinically manifested by one or more of a triad of visible palatal anomalies including submucous deficiency of the hard palate, bifid uvula, and a diastasis of velar musculature) and congenital palatal incompetence Type 2 (no visible velar anomalies but radiographic anomalies of the velopharyngeal region such as short or thin velum and/or enlarged nasopharyngeal dimensions consequent to vertebral and skull base anomalies). Middle ear disease was assessed separately in CPI Types 1 and 2 in order to differentiate the effects upon middle ear function between overt and occult velar anomalies. Middle ear disease was more frequent in CPI Type 1 than in CPI Type 2. The predominant otopathologic finding was serous otitis media, paralleling the type associated with cleft palate. Tympanic membrane atrophy, tympanosclerosis and tympanic membrane perforation, often considered sequelae of chronic serous otitis media, were noted infrequently. This investigation supports the concept that middle ear disease frequently occurs with congenital palatal incompetence as it does with cleft palate.

Nasal air flow was measured during the speech of 112 normal subjects (59 females and 53 males) ranging in age from three years to 37 years, six months. Flow was zero during nearly all oral consonant and vowel utterances, suggesting that velopharyngeal closure was air-tight. Flow occurred during all nasal consonants and during vowels adjacent to nasal consonants. These effects were interpreted as showing that progressively older subjects and female subjects demonstrate earlier anticipatory coarticulation in preparation for forthcoming nasal consonants.

Of one hundred patients with velopharyngeal incompetence subjected to a pharyngoplasty selected on the results of endoscopic and radiological examination 97% were cured of unacceptable nasal escape and 93% of unacceptable nasal resonance on the criteria described. It was considered that this provided a vindication of the system of treatment. Critical examination of the morbidity revealed an unacceptably high proportion of hyponasality. This appeared to be due to ignoring the criteria for selection for pharyngoplasty and opting for the more radical operation resulting in over-treatment in some cases. With the numbers available in the smaller treatment groups it was not possible to state that there was no significant difference in the results between the different pharyngoplasties in the groups for which they were selected. It is expected that there will be a larger proportion of patients receiving less radical treatment without detriment to the success rate, but with a lower morbidity. Assuming that it is accepted that as much accurate information as possible prior to operation is needed for the correct selection of operation, simultaneous endoscopic and radiological examination provide a time- and cost-efficient system the benefit of which becomes overwhelming for revision of the failed pharyngoplasty.

At present, there are a number of instrumental devices that can be used to supplement information obtained by the experienced clinician. Although each has its proponents, there continue to be distinct disadvantages associated with all of them. From a clinician's standpoint, the most frustrating limitation is that instruments with demonstrated reliability and validity typically cannot be used comfortably with pre-school children (Table 1). This is extremely unfortunate because those teams wishing to normalize a youngster's velopharyngeal mechanism prior to school enrollment still must rely almost exclusively upon the ear of the clinician for assessment. It is hoped that future research will address this important issue.

The characteristics of rigid and flexible endoscopes have been studied with reference to their suitability for nasal pharyngoscopy in the assessment of velopharyngeal incompetence taking into account a number of fallacies which are known to exist. It is concluded that the ability to achieve correct positioning of the rigid endoscope and the wide angle field of view of the 70 degrees Storz-Hopkins nasopharyngoscope, in particular, made it the best single instrument at present available for this work despite the greater ease of introduction of the flexible endoscopes. The characteristics of the information obtained by radiological examination were studied and in comparison with endoscopic information it was concluded that endoscopic information was more reliable for qualitative and radiological for quantitative analysis. The systems were considered to be mutually complementary and simultaneous examination with, preferably, synchronous recording provided the advantages of optimal placement of the endoscope and the possibility of measurement of the velopharyngeal isthmus.

Forty-five randomly selected patients with unilateral cleft lip, alveolus, and palate, all operated upon by Dr. Wolfram Schweckendiek were evaluated by three American specialists to assess the validity of primary veloplasty. Examination revealed an unusually high incidence of short palate and poor mobility of the soft palate. Facial growth was found to be highly acceptable in the majority of the patients. Unusually high incidence of velopharyngeal incompetence was found in these patients.

The aerodynamic oral-nasal factors related to the speech of two groups of cleft-palate children were evaluated. One group presented hypernasality and the other group presented normal nasal resonance. The aerodynamic parameters evaluated were oral pressure, nasal flow, and flow-pressure ratio (nasal flow/oral pressure). Oral temperature readings were also obtained. These parameters were evaluated under three conditions (1) blowing, (2) vocalizing the vowel /i/, and (3) reading eight sentences representing two different rhythm patterns, two types of consonant loadings, and two conditions of syllable stress. The findings revealed significant differences between the hypernasal and normal resonance groups in flow-pressure ratio, oral pressure, and nasal flow while subjects were reading sentences. However, only a small proportion of the variability in these aerodynamic measurements could be accounted for based on the classification of hypernasality or normal nasal resonance. Oral-nasal aerodynamic studies done during speaking activity are more useful clinically than blowing activity or saying vowel sounds. No aerodynamic differences were noted between the two groups for the different rhythm and stress patterns and phonemic loadings within the sentences used.

Twenty-two patients with the Facio-Auriculo-Vertebral Malformation Complex (hemifacial microsomia) were examined with multi-view videofluoroscopy and nasopharyngoscopy at rest and during speech. Fifty-five per cent of the subjects had velopharyngeal insufficiency (VPI) and hypernasal speech. Only two of these 12 subjects had cleft palate. VPI was related to structural and physiological asymmetry of the pharynx. No relationship was found between the severity of facial malformation and the presence of VPI.

Changes in velar position during production of nonnasal speech in two adults were measured using field-by-field videoendoscopic tracking procedures. The data suggested that the changes in velar position were coordinated with syllable production. Peak velar displacement occurred during maximum oral closure for oral consonant production and was followed by lowering of velar position during vowel production. This pattern of velar movement was not altered by changes in speaking rate or by jaw fixation. The timing of peak velar elevation relative to peak intraoral air pressure and peak jaw elevation was also examined. Timing of peak velar displacement was statistically associated with timing of peak intraoral air pressure in one subject. The data are discussed with regard to the potential value of studying variations in velar position during nonnasal speech in patients with marginal velopharyngeal incompetence.

In a 66-year-old woman signs and symptoms of bilateral opercular syndrome (Foix-Chavany-Marie-syndrome) developed progressively over a period of more than 10 years. Facio-linguo-velopharyngeo-masticatory diplegia with automatic-voluntary dissociation was accompanied by motor aphasia and oral apraxia leading to a state of almost complete anarthria. Although it initially resembled the anterior biopercular syndrome there are also features indicating involvement of the posterior opercula. Although the aetiology remains obscure without pathological data, a bilateral focal brain atrophy is assumed. This is probably the first case documented by MRI and SPECT.

It is reported frequently that individuals with palatal clefts have a high occurrence of laryngeal/voice symptoms. It has been speculated that vocal pathology in this population is the result of laryngeal compensation for abnormal velopharyngeal valving. This paper describes the prevalence of laryngeal/voice findings in a group of 85 patients referred for multimethod evaluation of velopharyngeal dysfunction. Forty-one percent of the patients had auditorily perceived voice symptoms and/or observable laryngeal abnormalities. Twenty-one percent of the patients had vocal fold nodules or thickened vocal folds. There was no clear relationship between laryngeal/voice findings and nasoendoscopic or aerodynamic assessments of velopharyngeal dysfunction. However, there was a significant relationship between laryngeal/voice findings and estimated subglottal pressure. Patients with laryngeal/voice findings (with or without nodules) had average estimated subglottal pressure values which were outside the normal range more often than patients without laryngeal/voice findings. These results suggest patients referred for assessment of velopharyngeal dysfunction should receive a comprehensive evaluation which includes screening laryngeal structure and function.

To summarize briefly, in our opinion, the combined use of end-viewing flexible fiber optic nasopharyngoscopy and multiview videofluoroscopy (which must include lateral and frontal views) and a behavioral assessment of the patient's speech provides the examiner with all of the information necessary to select the appropriate treatment for VPI. Indirect assessment procedures, such as airflow studies, do not enhance the decision making process even though they may provide what would appear to be objective data. Treatment decisions depend on the ability to confirm the type of speech abnormality present (by behavioral assessment) followed by a direct view of the defect (by endoscopy and fluoroscopy).

Forty-eight subjects with repaired palatal clefts were divided into three major groups on the basis of speech symptoms and were examined for velopharyngeal valving integrity by means of the R-D nasal manometer, pressure-flow techniques, the Hunter oral manometer, and videofluoroscopy. Videofluoroscopy appeared to provide data that most nearly agreed with predictions of valving made from speech. The Hunter oral manometer was the least useful of the four techniques.

This paper established a quantitative methodology for evaluating the velopharyngeal function (VPF) using NPF. The reliability of this method was testified. On the basis of this result, the observation of normal velopharyngeal function was carried out in 170 normal individuals. The authors presented the percentage of VPI during phonating five Chinese vowels, the highest one was "a" (52.3%), the lowest ones were "i" and "u" (7.1% and 5.3%). The extent of VPI was measured, the mean of "a"'s RVPI was 13.9%, and the means of "i"'s and "u"'s RVPI were 9.3% and 9.7% respectively. The authors suggested the RVPI "i" and RVPI "u" as two parameters for assessing VPF.

A study of velopharyngeal status after partial excision of musculus uvulae, as in total uvulectomy, has been carried out in 15 adults with normally formed soft palates. Fifteen volunteers matched for age and sex with normal palates, who had not had total uvulectomy, were used as controls. Four assessment techniques were used: Air escape, with modified tongue anchor technique; Production of speech sounds; Transnasal nasopharyngoscopy; and Radiological screening. Even though Azzam and Kuehn (1977) have stressed the importance of the musculus uvulae in velopharyngeal closure, all assessments showed that partial excision of the musculus uvulae, as in total uvulectomy, has no statistically significant effect on the velopharyngeal status in subjects with a normally formed soft palate.

Although sophisticated techniques for estimating velopharyngeal port area during speech are available, clinicians continue to seek approaches for screening patients with suspected velar inadequacy. The aim of the present study is to determine the sensitivity and specificity of predicting velopharyngeal dysfunction based on nasal airflow measurements. The pressure-flow technique was used to measure velopharyngeal orifice area and nasal airflow rate in 211 subjects with cleft palate or velar dysfunction, or both. The data demonstrate that nasal airflow rates above 125 cc/sec are almost always associated with velar dysfunction. Sensitivity and specificity of this index were high (0.85 and 0.96, respectively). A correct diagnosis was made in 93% of the cases. As expected, errors in judgment occurred most frequently in subjects with borderline velopharyngeal inadequacy.