351. Further Evidence for the Lymphocytic Nature of Leukaemic Reticuloendotheliosis (Hairy-Cell Leukaemia)
- Author
-
B. Speck, W. Knappp, H. L. Haak, J. C. H. De Man, and W. Hijmans
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Acid Phosphatase ,Cell ,Fluorescent Antibody Technique ,Immunoglobulins ,Biology ,Immunofluorescence ,Hypergammaglobulinemia ,Lectins ,Leukocytes ,medicine ,Humans ,Lymphocytes ,Lymphatic Diseases ,Leukemia ,medicine.diagnostic_test ,Histocytochemistry ,Hairy cell leukaemia ,Technetium ,Immunoglobulin D ,Hematology ,Immunoglobulin E ,Middle Aged ,Leukaemic reticuloendotheliosis ,Peripheral blood ,Blood Cell Count ,Uric Acid ,Microscopy, Electron ,medicine.anatomical_structure ,Immunoglobulin M ,Splenomegaly ,Reticular connective tissue ,Prothrombin Time ,Chlorambucil - Abstract
Summary. A case of hairy-cell leukaemia was studied by conventional cyto-chemical, electronmicroscopic and immunofluorescence techniques. This condition is often known as leukaemic reticuloendotheliosis (LRE) but the nature of the proliferating cells has been in doubt. The accumulation of immunoglobulin-synthesizing cells in the peripheral blood suggests that the involved cells are lymphocytes and no evidence for a reticular or endothelial origin of the LRE cell could be found.
- Published
- 1974