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• Probiotics ameliorate cognitive impairment in SAMP8 mice. • Probiotics modulate gut microbiota and SCFAs concentration in SAMP8 mice. • Probiotics reduced neural injury in SAMP8 mice. • Probiotics reduce Aβ, Tau pathology and neuroinflammation in SAMP8 mice. • Probiotics regulate the phosphorylation of AKT/GSK-3β pathway in SAMP8 mice. Alzheimer's disease (AD), the most prevalent type of dementia, still lacks disease-modifying treatment strategies. Recent evidence indicates that maintaining gut microbiota homeostasis plays a crucial role in AD. Targeted regulation of gut microbiota, including probiotics, is anticipated to emerge as a potential approach for AD treatment. However, the efficacy and mechanism of multi-strain probiotics treatment in AD remain unclear. In this study, 6-month-old senescence-accelerated-mouse-prone 8 (SAMP8) and senescence-accelerated-mouse-resistant 1 (SAMR1) were utilized. The SAMP8 mice were treated with probiotic-2 (P2, a probiotic mixture of Bifidobacterium lactis and Lactobacillus rhamnosus) and probiotic-3 (P3, a probiotic mixture of Bifidobacterium lactis , Lactobacillus acidophilus , and Lactobacillus rhamnosus) (1 × 109 colony-forming units) once daily for 8 weeks. Morris water maze (MWM) and novel object recognition (NOR) tests were employed to assess the memory ability. 16S sequencing was applied to determine the composition of gut microbiota, along with detecting serum short-chain fatty acids (SCFAs) concentrations. Neural injury, Aβ and Tau pathology, and neuroinflammation level were assessed through western blot and immunofluorescence. Finally, potential molecular mechanisms was explored through transcriptomic analysis and western blotting. The MWM and NOR test results indicated a significant improvement in the cognitive level of SAMP8 mice treated with P2 and P3 probiotics compared to the SAMP8 control group. Fecal 16S sequencing revealed an evident difference in the α diversity index between SAMP8 and SAMR1 mice, while the α diversity of SAMP8 mice remained unchanged after P2 and P3 treatment. At the genus level, the relative abundance of ten bacteria differed significantly among the four groups. Multi-strain probiotics treatment could modulate serum SCFAs (valeric acid, isovaleric acid, and hexanoic acid) concentration. Neuropathological results demonstrated a substantial decrease in neural injury, Aβ and Tau pathology and neuroinflammation in the brain of SAMP8 mice treated with P3 and P2. Transcriptomic analysis identified the chemokine signaling pathway as the most significantly enriched signaling pathway between SAMP8 and SAMR1 mice. Western blot test indicated a significant change in the phosphorylation level of downstream AKT/GSK-3β between the SAMP8 and SAMR1 groups, which could be reversed through P2 and P3 treatment. Multi-strain probiotics treatment can ameliorate cognitive impairment and pathological change in SAMP8 mice, including neural damage, Aβ and Tau pathology, and neuroinflammation. This effect is associated with the regulation of the phosphorylation of the AKT/GSK-3β pathway. [ABSTRACT FROM AUTHOR]

In human cooperation, people prefer to choose partners with high willingness and ability—while both are valued by partners, individuals often prioritize willingness. Two event‐related potential (ERP) experiments were conducted to discern the neural processes underpinning this preference. In the first experiment, participants made a choice between two potential partners and received feedback on the selected partner's willingness to cooperate. This was followed by feedback on the partner's task performance (ability) or a gambling outcome. In contrast, the second experiment first provided feedback on ability, then presented feedback on willingness or a gambling outcome. This study revealed that a potential partner's willingness trait significantly influences individuals' emotional evaluations and monetary allocations than the ability trait. Electrophysiological data indicated that low‐willingness feedback elicited a diminished feedback‐related negative (FRN) and an amplified P3 compared to high‐willingness feedback. In contrast, no such difference was discernible between high‐ and low‐ability feedback. Moreover, the P3 difference from high versus low willingness was considerably more pronounced than that from gambling outcomes, whereas the difference wave between high and low ability paralleled gambling outcomes. These findings bolster the novel finding that partner willingness may provide more substantial social rewards than ability. Furthermore, this study provides the first ERP evidence of willingness and ability trait perceptions in partner choice decisions. This study firstly combines behavioral analysis with event‐related potential (ERP) data to explore the psychological mechanisms underlying the preference for willingness over ability in partner choice. Our findings indicate that willingness feedback more significantly influences emotions, allocation behaviors, and feedback‐related brain electrophysiological components compared to ability feedback, suggesting that willingness may offer more substantial social rewards. The study offers a novel theoretical perspective in understanding the preference for willingness. [ABSTRACT FROM AUTHOR]

Background: Gambling is a popular leisure activity in many countries, often expected to boost regional economies. Nevertheless, its negative impacts remain a significant concern. Gambling disorder is recognized as the most severe consequence; however, even non- or low-risk gamblers may also face negative impacts. This study aimed to estimate the number of Japanese gamblers experiencing gambling-related harm (GRH) and its distribution across six life domains, financial, relational, emotional, health, social and other aspects, based on the severity of their problem gambling risk. Methods: This cross-sectional study relied on an online survey conducted between August 5 and 11, 2020. Participants aged 20 years and above, who engaged in gambling during 2019 were recruited via a market research company. The survey assessed the prevalence of GRH 72 items among four gambler risk groups (non-problem, low-, moderate-, and high-risk), as categorized by the Problem Gambling Severity Index. The data was adjusted for population weighting using representative national survey data: the 2017 Comprehensive Survey of Living Conditions and the 2017 Epidemiological Survey on Gambling Addictions. Results: Out of the 28,016 individuals invited to the survey, 6,124 participated in the screening, 3,113 in the main survey, and 3,063 provided valid responses. After adjusting the survey data, it was estimated that 39.0 million (30.8%) of Japan's 126.8 million citizens gambled in 2019. Among them, 4.44 million (11.4%) experienced financial harm, 2.70 million (6.9%) health harm, 2.54 million (6.5%) emotional harm, 1.31 million (3.4%) work/study harm, 1.28 million (3.3%) relationship harm, and 0.46 million (1.2%) other harm. Although high-risk gamblers experienced severe harm at the individual level, over 60% of gamblers who experienced GRHs were non- and low-risk gamblers, with the exception of other harm, at the population level. Conclusions: The study highlighted the prevention paradox of gambling in Japan. While national gambling policies primarily focus on the prevention and intervention for high-risk gamblers, a more effective approach would involve minimizing GRH across the entire population. [ABSTRACT FROM AUTHOR]

AbstractBackgroundMethodResultsConclusionsThe stigmatization of addiction has been identified as a barrier to treatment-seeking among individuals with substance use concerns. Although some evidence exists that beliefs in different models of addiction (MOAs) are associated with stigma, the research is limited in several ways. The aim of the current study is to understand the relationship between different MOAs and public stigma toward substance use disorders and behavioral addictions.Participants were 755 adults who completed an online survey on MTurk (Mage = 36.2, SD = 10.1, 40.3% women, 59.4% men) and were randomized to one of four vignette conditions describing an individual with alcohol use disorder, opioid use disorder, problem gambling disorder, or diabetes. Participants completed measures assessing perceived stigma toward the vignette character and beliefs related to five MOAs (disease, moral, psychological, sociological, nature).Stigma ratings were significantly higher in the alcohol and opioid use disorder conditions compared to the problem gambling and diabetes conditions. Greater beliefs in the disease MOA were associated with greater stigma in the problem gambling condition, whereas greater beliefs in the moral MOA were associated with greater stigma in all addiction conditions. Greater beliefs in the psychological MOA were associated with lower stigma in the opioid use disorder and problem gambling conditions.The current study provides further support that addictive disorders are more stigmatized than other health disorders and suggests that beliefs in specific MOAs are differentially associated with stigma. Interventions addressing addiction stigma may consider incorporating information emphasizing MOAs that are less stigmatizing. [ABSTRACT FROM AUTHOR]

AbstractA broad quantitative literature has explored the extent and distribution of gambling-related harm. However, any quantitative measure involves a number of statistical decisions around item selection and weighting that may affect its ability to provide an accurate summary of a gambler’s lived experience. This may especially be an issue with a condition as varied and multifaceted as gambling-related harm. The present research therefore used qualitative methods to validate the categorization of gamblers into four levels of harm via the Gambling Harms Scale (10-items) (GHS-10) through an analysis of 30 semi-structured interviews with gamblers. Results showed that unharmed gamblers saw gambling as just another leisure activity, which relieved stress and brought them closer to other people. Low harm gamblers were similar but could experience emotional stresses over their level of gambling expenditure. Just under half of all moderate harm gamblers experienced occasional severe financial impacts and emotional stresses from their gambling. Finally, all high harm gamblers experienced chronic financial impacts and emotional stresses, which spilled over into relationship problems for three quarters of this group, and negative impacts on health or work/study for around half of this group. These results showed that the severity of participants’ lived experience of gambling increased with their GHS-10 score, providing a qualitative validation for this quantitative self-report measure. This qualitative validation for a quantitative scale is argued to be a promising avenue for future gambling research. [ABSTRACT FROM AUTHOR]

Background: Gambling and gambling-related harm attract significant researcher and policy attention. The liberalisation of gambling in most western countries is strongly associated with a marked rise in gambling activity and increases in gambling-related harm experienced at the population level. Programs to address gambling-related harm have traditionally focused on individuals who demonstrate problematic gambling behaviour, despite clear evidence of the effectiveness of a public health approach to high-risk activities like gambling. Little is known about the availability or efficacy of programs to address gambling-related harm at a population level. Methods: The Victorian Responsible Gambling Foundation commissioned a rapid evidence review of the available evidence on programs designed to reduce gambling-related harm at a population level. The review was conducted using a public health and harm reduction lens. MEDLINE, ProQuest Central and PsychInfo databases were searched systematically. Included studies were published in English between 2017 – 2023 from all countries with gambling policy contexts and public health systems comparable to Australia's; included primary data; and focused on primary and/or secondary prevention of gambling-related harm or problems. Results: One hundred and sixty-seven articles were eligible for inclusion. Themes identified in the literature included: risk and protective factors; primary prevention; secondary prevention; tertiary prevention; target population group; and public health approach. The evidence review revealed a gap in empirical evidence around effective interventions to reduce gambling-related harm at the population level, particularly from a public health perspective. Conclusions: Addressing gambling-related harm requires a nuanced, multi-layered approach that acknowledges the complex social, environmental, and commercial nature of gambling and associated harms. Moreover, evidence demonstrates community programs to reduce gambling-related harm are more successful in reducing harm when based on sound theory of co-design and address the social aspects that contribute to harm. [ABSTRACT FROM AUTHOR]

While the concept of recovery is receiving increasing attention in the context of gambling disorder (GD), no consensus has yet been reached regarding its definition. This scoping review aims to map the literature on GD recovery, identify gaps, and provide insights for a more holistic and patient-centred perspective. A systematic search of three databases was conducted (PubMed, PsycINFO, and ScienceDirect). Based on the method by which the results of these studies were produced, the studies included were sorted into four categories (quantitative, instrument validation, qualitative, and mixed studies) and subsequently examined using conceptual analysis. One hundred thirteen articles were included in this research after the screening process. In the quantitative and instrument validation studies, recovery was defined or operationalized in terms of abstinence, the absence of a GD diagnosis, or mild GD severity, or by reference to treatment outcomes or controlled gambling. A meta-synthesis of the results of the qualitative studies revealed four core features of recovery (insight, empowerment and commitment, wellbeing enhancement, and reconsideration of the issue of relapse). Discrepancies in definitions, outcomes, and variables used were evident across studies. Additionally, the quantitative and standardized approaches employed in most studies exhibited severe limitations with regard to defining recovery from the subjective and multidimensional perspectives of people recovering from GD. This lack of definitional clarity emphasizes the necessity for further qualitative research. This research should encompass multiple stakeholder perspectives to develop a working definition promoting recovery from a holistic, patient-centred, and tailored approach. [ABSTRACT FROM AUTHOR]

Gambling addiction is increasing and is becoming a public health concern due to the rise of gambling-related harms affecting the youth. Previous studies suggest a strong link between problem gambling (PG) and substance use and psychosocial and familial factors. Our main objective was to analyze the association between PG and factors like sport, leisure-time activities, and risk-taking behaviors in adolescents. A survey on substance use and addictive behaviors was performed in 2019 on a representative sample of 2240 subjects (14–18 years) from the Southern Spain Region. Data variables like socio-demographic characteristics, sport, leisure and free time activities, family environment, PG (Lie-Bet Scale), compulsive internet use (CIUS Scale), and consumption of alcohol and cannabis were collected using a standardized questionnaire. Weighted PG prevalence was estimated in either sex, as well as the differences between various levels of PG using chi-square tests. Crude and adjusted weighted logistic regression models were used to identify predictors associated with PG. The prevalence of PG was associated with shopping frequency, compulsive internet use, cannabis use in the previous month, higher family economic status, and having a homemaker father which increased the likelihood of PG. On the contrary, cultural hobbies such as playing an instrument, painting, singing, and writing, and having a working mother were inversely associated with PG. Our results suggest that encouraging participation in creative activities along with supervised shopping and monitoring compulsive internet use and cannabis consumption may contribute some protection against adolescent PG. [ABSTRACT FROM AUTHOR]

Excessive leisure-time television viewing in childhood has been associated with a range of poorer outcomes in adulthood and may represent an early form of addictive disorder. As addictive disorders are often correlated, we tested the hypothesis that television viewing in childhood and adolescence would be longitudinally associated with adulthood substance-related and behavioural addictive disorders in a population-based cohort born in 1972/1973. Weekday television viewing time was reported at multiple ages from 5 to 15 years, and criteria for alcohol, cannabis, and tobacco use disorders and disordered gambling were assessed at multiple adult ages up to 45 years. Higher television viewing times were associated with a greater likelihood of meeting diagnostic criteria for all substance-related disorders and disordered gambling in models that were adjusted for sex (p values < 0.05). After adjustment for childhood socioeconomic status and childhood self-control, mean television viewing time (hours/day) remained associated with tobacco use disorder (OR = 1.22, 95% CI = 1.04–1.42, p = 0.017) and disordered gambling (OR = 1.33, 95% CI = 1.07–1.66, p = 0.010). Excessive, leisure-time television viewing in childhood and adolescence may be a modifiable risk factor for tobacco use disorder and/or disordered gambling in later life. [ABSTRACT FROM AUTHOR]

Interoception is one of the pivotal cognitive functions for mechanisms of our body awareness, and malfunction of the interoceptive network is thought to be associated with mental illness, including addiction. Within addictive disorders, substance‐based and non‐substance‐based addictions are known to hold dissociable reward systems. However, little is known about how interoceptive awareness between these addiction sub‐types would differ. Subjective interoceptive awareness was assessed among patients with alcohol use disorder (n = 50) who were subsequently hospitalized or remained out‐patient and gambling addiction (n = 41) by the Body Awareness component of the Japanese version of the Body Perception Questionnaire (BPQ‐VSFBA‐J) and compared them against healthy control (n = 809). Both addiction groups showed significantly lower BPQ than the control, with no substantial differences between inpatients and outpatients for alcohol samples. Notably, BPQ scores for gambling patients were significantly lower than those for the alcohol group. This evidence may suggest a putative role of interoceptive ability on the severity of behavioral addiction over substance‐based addiction. [ABSTRACT FROM AUTHOR]

Objective: The paper conducts a network analysis of the fragmented literature on brand and addiction. Method: A thematic map, thematic evolution, word cloud, co-citation analysis, and cooperation networks were utilized to identify brand addiction study trends and topics. Results: The data show that marketing and psychiatry have interdisciplinary groupings and multidisciplinary publications. These groups reflect societal changes, particularly the shift from traditional to digital challenges. Fast food addiction is different from alcohol and cigarette addictions due to its ease and extensive marketing. The decline in internet and gambling addiction suggests a shift in priorities. Conclusions: This research helps researchers, policymakers, and practitioners in addiction prevention and intervention. The study also understands brand addiction and its effects on psychology, psychiatry, and management by providing insights into emerging topics, thematic maps and evolution of studies, collaboration opportunities, geographical distribution of studies, and more. [ABSTRACT FROM AUTHOR]

Introduction: Problem gambling (PBG) is more common in people with mental health disorders, including substance use, bipolar, and personality disorders, than in the general population. Although individuals with psychotic disorders might be expected to be more vulnerable to PBG, fewer studies have focused on this comorbidity. The aim of this review was to estimate the prevalence of PBG in people with psychotic disorders. Methods: Medline (Ovid), EMBASE, PsycINFO (Ovid), CINAHL, CENTRAL, Web of science, and ProQuest were searched on November 1, 2023, without language restrictions. Observational and experimental studies including individuals with psychotic disorders and reporting the prevalence of PBG were included. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal for systematic reviews of prevalence data. The pooled prevalence of PBG was calculated using a fixed effects generalized linear mixed model and presented through forest plots. Results: Of 1271 records screened, 12 studies (n = 3443) were included. The overall prevalence of PBG was 8.7% (95% CI = 7.8%–9.7%, I2 = 69%). A lower prevalence was found in studies with a low risk of bias (5.6%; 95% CI = 4.4%–7.0%) compared with studies with a moderate risk of bias (10.4%; 95% CI = 9.2%–11.7%). Different methods used to assess PBG also contributed to the heterogeneity found. Conclusion: This meta‐analysis found substantial heterogeneity, partly due to the risk of bias of the included studies and a lack of uniformity in PBG assessment. Although more research is needed to identify those at increased risk for PBG, its relatively high prevalence warrants routine screening for gambling in clinical practice. [ABSTRACT FROM AUTHOR]

Background: Gambling Disorder (GD) is a bio-psycho-social disorder resulting from the interaction of clinical, cognitive, and affective factors. Impulsivity is a crucial factor in addiction studies, as it is closely linked to cognitive distortions in GD by encompassing impulsive choices, motor responses, decision-making, and cognitive biases. Also, emotions, mood, temperament, and affective state are crucial in developing and maintaining GD. Gambling can be used as a maladaptive coping strategy to avoid or escape problems and distress. Methods: The aim of the present study is to explore differences in personality traits and emotion regulation of people suffering from GD, substance-dependent gamblers (SDGs), and healthy controls (HCs). Additionally, the study proposes a new experimental task: the "Gambling Affective Task" (GAT) to investigate the influence of affective priming on risk-taking behaviors. Results: Our findings indicate that participants placed lower bets following positive priming. Additionally, SDGs wagered significantly higher amounts than HCs, regardless of priming type. In general, participants exhibited longer response times after positive priming trials, compared to negative and neutral priming trials. These findings suggest that experiencing positive emotions can act as a protective factor by delaying and lengthening gambling behaviors. By comparing gamblers with and without substance comorbidity, we can gain insight into the exclusive factors of GD and improve our understanding of this disorder. Conclusions: By elucidating the impact of emotional states on risk-taking, the research also provides new insights into the prevention and treatment of GD. [ABSTRACT FROM AUTHOR]

Background: Gambling abstinence when underage lowers the risk of harmful gambling in later life. However, little research has examined why many young people refrain from gambling, even though this knowledge can inform protective strategies and lower risk factors to reduce underage gambling and subsequent harm. This study draws on the lived experience of adolescent non-gamblers to explore how social determinants while growing up have shaped their reasons and choices to not gamble. Methods: Fourteen Australian non-gamblers, aged 12–17 years, participated in an in-depth individual interview (4 girls, 3 boys) or online community (4 girls, 3 boys). Questions in each condition differed, but both explored participants' gambling-related experiences while growing up, including exposure, attitudes and behaviours of parents and peers, advertising, simulated gambling and motivations for not gambling. The analysis used adaptive grounded theory methods. Results: The grounded theory model identifies several reasons for not gambling, including not being interested, being below the legal gambling age, discouragement from parent and peers, concern about gambling addiction and harm, not wanting to risk money on a low chance of winning, and moral objections. These reasons were underpinned by several social determinants, including individual, parental, peer and environmental factors that can interact to deter young people from underage gambling. Key protective factors were parental role modelling and guidance, friendship groups who avoided gambling, critical thinking, rational gambling beliefs, financial literacy and having other hobbies and interests. Conclusions: Choices to not gamble emanated from multiple layers of influence, implying that multi-layered interventions, aligned with a public health response, are needed to deter underage gambling. At the environmental level, better age-gating for monetary and simulated gambling, countering cultural pressures, and less exposure to promotional gambling messages, may assist young people to resist these influences. Interventions that support parents to provide appropriate role modelling and guidance for their children are also important. Youth education could include cautionary tales from people with lived experience of gambling harm, and education to increase young people's financial literacy, ability to recognise marketing tactics, awareness of the risks and harms of gambling, and how to resist peer and other normalising gambling influences. [ABSTRACT FROM AUTHOR]

Behavioral and biological addictions can impair decision-making processes, mainly by means of a dysfunction in brain regions associated with reward and frontal areas that may lead to disadvantageous choices. Understanding these differences helps establish appropriate terminology and enhances our ability to recognize, prevent, and treat these disorders effectively. Thus, while behavioral and biological addictions share some common elements, their underlying mechanisms and impact on decision-making vary significantly. Moreover, decision-making can be measured through questionnaires (stable or "cold" measures) or dynamic tasks (hot decisions) such as the Iowa Gambling Task (IGT), which can reflect different dimensions of this process. The aim of this study was to compare decision-making from different perspectives—stable and dynamic measures—in patients with gambling addiction (GA) (n = 42) and patients with biological addictions (BA) (n = 43). Decision-making was assessed using GDMS (Decisional Styles) and the LCT (Loss Aversion), as cold decision-making measures, as well as a hot or situational task called the IGT (Iowa Gambling Task). The results revealed that GA patients exhibited lower rational style scores compared to BA patients. Additionally, GA patients showed greater loss aversion according to the LCT questionnaire. On the other hand, when analyzing the IGT results, no differences were observed between groups in the overall IG index, learning curves, or the loss aversion parameter. However, GA patients showed higher sensitivity to feedback and less consistency in their decisions. These findings highlight the differences between different types of addictions and highlight the importance of considering the type of measure used to evaluate decision-making. [ABSTRACT FROM AUTHOR]

Impulsive traits (i.e., the tendency to act without forethought regardless of negative outcomes) are frequently found in healthy populations. When exposed to risk factors, individuals may develop debilitating disorders of impulse control (addiction, substance abuse, gambling) characterized by behavioral and cognitive deficits, eventually leading to huge socioeconomic costs. With the far-reaching aim of preventing the onset of impulsive disorders, it is relevant to investigate the topological organization of functional brain networks associated with impulsivity in sub-clinical populations. Taking advantage of the open-source LEMON dataset, we investigated the topological features of resting-state functional brain networks associated with impulsivity in younger (n = 146, age: 20–35) and older (n = 61, age: 59–77) individuals, using a graph-theoretical approach. Specifically, we computed indices of segregation and integration at the level of specific circuits and nodes known to be involved in impulsivity (frontal, limbic, and striatal networks). In younger individuals, results revealed that impulsivity was associated with a more widespread, less clustered and less efficient functional organization, at all levels of analyses and in all selected networks. Conversely, impulsivity in older individuals was associated with reduced integration and increased segregation of striatal regions. Speculatively, such alterations of functional brain networks might underlie behavioral and cognitive abnormalities associated with impulsivity, a working hypothesis worth being tested in future research. Lastly, differences between younger and older individuals might reflect the implementation of age-specific adaptive strategies, possibly accounting for observed differences in behavioral manifestations. Potential interpretations, limitations and implications are discussed. [ABSTRACT FROM AUTHOR]

Impaired decision‐making is often displayed by individuals suffering from gambling disorder (GD). Since there are a variety of different phenomena influencing decision‐making, we focused in this study on the effects of GD on neural and behavioural processes related to loss aversion and choice difficulty. Behavioural responses as well as brain images of 23 patients with GD and 20 controls were recorded while they completed a mixed gambles task, where they had to decide to either accept or reject gambles with different amounts of potential gain and loss. We found no behavioural loss aversion in either group and no group differences regarding loss and gain‐related choice behaviour, but there was a weaker relation between choice difficulty and decision time in patients with GD. Similarly, we observed no group differences in processing of losses or gains, but choice difficulty was weaker associated with brain activity in the right anterior insula and anterior cingulate cortex in patients with GD. Our results showed for the first time the effects of GD on neural processes related to choice difficulty. In addition, our findings on choice difficulty give new insights on the psychopathology of GD and on neural processes related to impaired decision‐making in GD. [ABSTRACT FROM AUTHOR]

Background: The primary objective of the current paper was to assess the psychometric attributes of the Persian version of the Online Gambling Symptom Assessment Scale (P-OGSAS) within the Iranian population. Methods: The current study was conducted through a convenient sampling method between September and November 2021, involving 187 participants who had experienced online gambling at least once a month for the last 3 months. OGSAS was translated from English into Persian using the forward-backward translation method. Cronbach's alpha coefficient and principal component analysis (PCA) were employed to evaluate the reliability and validity of the scale, respectively. Participants were administered a battery of assessments, including P-OGSAS, Persian Gambling Disorder Screening Questionnaire (GDSQ-P), Patient Health Questionnaire-9 Items (PHQ-9), and Generalized Anxiety Disorder Questionnaire (GADQ-7), to assess validity and reliability. Findings: The results showed that the 3-factor model of this scale provides the highest level of predictability. The 3-factor model accounts for 54.8% of the square load. With a Cronbach's alpha coefficient of 0.807, P-OGSAS demonstrated satisfactory reliability. Finally, OGSAS has a significant correlation with other scales, and as a result, this scale has suitable convergent validity. Conclusion: P-OGSAS can adequately assess the symptoms and severity of online gambling. Therefore, clinicians could use this scale to evaluate the problems related to online gambling in the Iranian population. [ABSTRACT FROM AUTHOR]

Introduction Excessive gambling can cause substantial biopsychosocial problems (e.g. difficulties with finances, relationships, mental, and physical health). For military Service Members, it can also result in security clearance denial or revocation, failure to achieve promotions, and premature career termination. Recent congressional mandates have obligated the U.S. Department of Defense to screen for problematic gambling, the predictive values of which are a function of (i) problem prevalence and (ii) tool sensitivity and specificity. This meta-review (i.e. systematic review of systematic reviews) on the screening properties of gambling assessment tools and the effectiveness of treatments for gambling disorder is to inform military services on responding to Service Members' gambling problems. Materials and Methods EBSCO Discovery Service, PubMed, PsycINFO, Ovid Medline, Social Care Online, Epistemonikos, International Health Technology Assessment, and the Cochrane Central Register of Controlled Trials electronic databases were searched up to December 2022 for systematic reviews and meta-analyses on measurements of adult subclinical or gambling, and interventions targeting individuals with GD. Three and four studies were included in each section of the current meta-review (i.e. assessment tools and treatment). For review 1, the estimated risk of bias was assessed using the Risk of Bias in Systematic Reviews. Results Thirty-one tools were identified through the three systematic reviews. All had modest sensitivities and specificities; combined with low prevalences in the general SM population, positive results would be incorrect 64-99% of the time. However, if screening were conducted with SMs referred for alcohol problems, a positive result on the best screening tools would be correct 76% of the time. Several commonly used treatment approaches had demonstrated efficacy for GD. Conclusions The combination of low prevalence of GD and subclinical gambling problems in the general population, coupled with modest sensitivity and specificity, makes screening unfeasible in the general SM population. However, dual-phase screening in higher-prevalence subpopulations (i.e. SMs already identified with substance-abuse or mental-health problems) would be viable. Regarding treatment, several interventions—already used in military healthcare—with extensive empirical track records have been successfully used to treat adults with GD. [ABSTRACT FROM AUTHOR]

This study explored the association between rewarding elements in videogames and adolescents' problematic gaming behavior, evaluating the extent to which individual vulnerabilities amplify this relationship. In a two-cohort-design the impact of rewarding elements on adolescents' problematic gaming was investigated: the first cohort consisted of 2708 secondary school students (53.9% male, M = 13.9 SD = 1.20), and the second cohort of 1616 (54.2% male, M = 14.7 SD = 1.28). As the type of games that participants were playing differed over time, the second cohort was treated as a replication of the first one. Results revealed that random, social, and contingencies rewards were associated with adolescents' problematic gaming in both cohorts. Games including these rewards were associated with an increased risk for problematic game-play. Moreover, results indicated that the association between contingencies rewards and problematic gaming behavior was stronger for adolescents with attention-deficit/hyperactivity disorder symptoms, while the association between social rewards and problematic gaming was stronger for adolescents with social problems. This study contributed to our understanding of the mechanisms that can explain why certain adolescents, particularly those with ADHD and/or socially vulnerable, are riskier to develop problematic gaming. These insights can contribute to a more tailored prevention and treatment approach aiming at problematic gaming among adolescents. [ABSTRACT FROM AUTHOR]

Gambling disorder affects 0.5–2% of the population, and of those who receive treatment, dropout tends to be relatively high. Very little is known about participant-specific variables linked to treatment discontinuation/dropout in gambling disorder, especially in pharmacological clinical trial settings. Data were pooled from eight previous randomized, controlled pharmacological clinical trials conducted in people with gambling disorder. Demographic and clinical variables were compared between those who did versus did not subsequently dropout from those treatment trials. The sample comprised data from 635 individuals, and the overall rate of treatment dropout was 40%. Subsequent treatment dropout was significantly associated with the following: positive family history of gambling disorder in one or more first degree relatives (relative risk [RR] of dropout in those with positive history vs not = 1.30), preference for mainly strategic vs non-strategic gambling activities (RR = 1.43), lower levels of education (Cohen's D = 0.22), and higher levels of functional disability (Cohen's D = 0.18). These variables did not differ significantly as a function of treatment condition (medication versus placebo). Dropouts and completers did not differ significantly in terms of the other demographic or clinical variables that were considered. This study identified several candidate participant-specific predictors of pharmacological treatment dropout in gambling disorder. The findings highlight the need for future studies to address a wider range of contextual variables at large scale (including also study-specific variables e.g. trial/intervention duration), including in naturalistic treatment and clinical trial settings, with a view to developing algorithms that might usefully predict dropout risk. [ABSTRACT FROM AUTHOR]

Background. The convergence process between gambling and gaming is raising concerns in legislative and policy arenas and blurring definitions in what is and is not considered gambling. Since social definitions influence perception of legitimacy which subsequently shapes behaviours, the present study aims to investigate perceptions and opinions of young Italian gamers on the similarities and differences between gaming and gambling. Methods. Six online focus groups with gamers aged 14–17 were conducted. The whole sample includes 22 male and 7 female gamers attending high school and living in North-West Italy. Results. Young gamers' definitions of gambling differed from official ones, where mechanisms like loot boxes and social casinos were perceived as gambling, though they do not entail cash wins. Participants also recognized that videogaming entails some risks – such as addiction – similar to those of gambling, and showed a certain degree of agency in adopting self-regulation practices aimed at reducing them. Conclusions. Research should focus more on what specific gaming mechanics are more likely to cause negative outcome, regardless of whether they are comparable to gambling or not, so that appropriate measures to limit risks can be introduced. To identify these mechanics, young gamers can provide crucial insights and knowledge. [ABSTRACT FROM AUTHOR]

Background: In 1990, the United States' Institute of Medicine promoted the principles of outcomes monitoring in the alcohol and other drugs treatment field to improve the evidence synthesis and quality of research. While various national outcome measures have been developed and employed, no global consensus on standard measurement has been agreed for addiction. It is thus timely to build an international consensus. Convened by the International Consortium for Health Outcomes Measurement (ICHOM), an international, multi-disciplinary working group reviewed the existing literature and reached consensus for a globally applicable minimum set of outcome measures for people who seek treatment for addiction. Methods: To this end, 26 addiction experts from 11 countries and 5 continents, including people with lived experience (n = 5; 19%), convened over 16 months (December 2018–March 2020) to develop recommendations for a minimum set of outcome measures. A structured, consensus-building, modified Delphi process was employed. Evidence-based proposals for the minimum set of measures were generated and discussed across eight videoconferences and in a subsequent structured online consultation. The resulting set was reviewed by 123 professionals and 34 people with lived experience internationally. Results: The final consensus-based recommendation includes alcohol, substance, and tobacco use disorders, as well as gambling and gaming disorders in people aged 12 years and older. Recommended outcome domains are frequency and quantity of addictive disorders, symptom burden, health-related quality of life, global functioning, psychosocial functioning, and overall physical and mental health and wellbeing. Standard case-mix (moderator) variables and measurement time points are also recommended. Conclusions: Use of consistent and meaningful outcome measurement facilitates carer–patient relations, shared decision-making, service improvement, benchmarking, and evidence synthesis for the evaluation of addiction treatment services and the dissemination of best practices. The consensus set of recommended outcomes is freely available for adoption in healthcare settings globally. [ABSTRACT FROM AUTHOR]

The purpose of this study was to explore the relationship between academic entitlement, gaming, addiction, and life balance. College students (n = 230) on academic probation (cumulative GPA < 2.0) enrolled at a large, public southern university participated in the study. We were able to successfully predict entitlement using life balance subscales; specifically, global health and quality of relationship subscale scores predicted academic entitlement. We did not find a significant relationship between gaming addiction and life balance. Additionally, we found that the probation students in this sample lead fairly balanced lives in most domains, but struggle with stress and academic entitlement to some degree. Implications and recommendations are also discussed. [ABSTRACT FROM AUTHOR]

Gaming is no longer just a recreational activity, but also a potential therapeutic tool for improving physical and mental well-being. Recent studies have shown that gaming can have positive effects on physical fitness, cognitive function, and brain development. Exergaming, which combines exercise and gaming, has been particularly effective in enhancing cardiovascular health, muscle strength, and coordination. Games like Pokémon Go can also improve psychological health and social outcomes. Additionally, gaming can foster social interaction and combat feelings of loneliness. However, it is important to moderate gaming and consider potential risks, such as musculoskeletal issues and exacerbation of mental health conditions. Overall, gaming has the potential to promote health and well-being when approached mindfully. [Extracted from the article]

This study aims to assess whether the presence of Internet Gaming Disorder (IGD) is associated with disease severity, Attention Deficit Hyperactivity Disorder(ADHD) presentation, emotional problems, behavioral problems, and CPT profile in patients with ADHD. Forty children with IGD and sixty-four patients without IGD were included in the study, all of whom had a diagnosis of ADHD. Comorbid psychiatric disorders were determined using The Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS). Conners's Parent Rating Scale-Revised Short form (CPRS-RS), The Strengths and Difficulties Questionnaire (SDQ), Internet Gaming Disorder Questionnaire (IGD-20), and MOXO Continuous Performance Test (MOXO d-CPT) were performed on the children, and Clinical Global Impression (CGI), Children's Global Assessment Scale (CGAS), comorbidities and ADHD presentations were evaluated. The IGD group was found to have the combined presentation of ADHD more commonly, and their CGI, CGAS, SDQ behavior problems subscale, cognitive problems, attention problems, and ADHD index in the CPRS-RS questionnaire were found to be higher (p < 0.05). No differences were found in attention, timing, impulsiveness, and hyperactivity scores in CPT between groups (p > 0.05). Our study has shown that children with both ADHD and IGD had more severe symptoms, more behavioral problems, and differences regarding the prevalence of the ADHD presentations when compared to children having ADHD without IGD. Longitudinal studies with higher sample sizes are required to investigate this possible connection in the context of a cause-effect relationship and draw a conclusion. [ABSTRACT FROM AUTHOR]

Deficits in cost/benefit decision making is a critical risk factor for gambling disorder. Reward‐paired cues may play an important role, as these stimuli can enhance risk preference in rats. Despite extensive research implicating the dorsal striatum in the compulsive aspects of addiction, the role of nigrostriatal dopaminergic activity in cue‐induced risk preference remains unclear, particularly in females. Accordingly, we examined the effects of manipulating the dopaminergic nigrostriatal pathway on cue‐induced risky choice in female rats. TH:Cre rats were trained on the cued version of the rat Gambling Task. This task was designed such that maximal reward is attained by avoiding the high‐risk, high‐reward options and instead favouring the options associated with lower per‐trial gains, as they feature less frequent and shorter time‐out penalties. Adding reward‐paired audiovisual cues to the task leads to greater risky choice on average. To assess the role of the nigrostriatal pathway, a viral vector carrying either Cre‐dependent inhibitory or excitatory DREADD was infused into the substantia nigra. Rats then received clozapine‐N‐oxide either during task acquisition or after a stable performance baseline was reached. Inhibition of this pathway accelerated the development of risk preference in early sessions and increased risky choice during performance, but long‐term inhibition actually improved decision making. Activation of this pathway had minimal effects. These results provide evidence for the involvement of the dopaminergic nigrostriatal pathway in cue‐induced risk preference in females, therefore shedding light on its role in cost/benefit decision‐making deficits and expanding our knowledge of the female dopaminergic system. [ABSTRACT FROM AUTHOR]

This article examines Thomas Jefferson's perspective on poverty in early America. Jefferson believed that poverty was a problem that needed to be addressed and that capable individuals had a responsibility to assist the needy. However, his definition of poverty was limited to white male laborers, excluding women, children, slaves, and Native Americans. Jefferson supported localized poor relief systems and viewed beggars as immoral and outside the organized charity system. He recognized the challenges faced by farmers and planters who struggled to make ends meet. Despite his optimism about the American poor-relief system, poverty remained a persistent issue in the country. [Extracted from the article]

Background: Internet Gaming Disorder (IGD) has been associated with symptoms of Digital Eye Strain (DES) and poor academic performance among adolescent students. The purpose of this study is to assess whether a student's achievement of a specific academic goal within a short period of time can be directly predicted by symptoms of IGD and DES. Methods: This is a cross-sectional survey of 140 high school graduates who received an examination of visual acuity as a pre-requisite for entering the written admission examinations of law enforcement and military academies. The students completed the Digital Eye Strain Questionnaire (DESQ) and the Ten-Item Internet Gaming Disorder Test (IGDT-10) and stated their own evaluation of their chances for success. They were contacted following their admission examinations, and their success or failure to be admitted was recorded. Results: The students with IGD symptomatology were more likely to present with symptoms of DES. They were also more pessimistic about their chances of success in the subsequent written admission examinations; none succeeded, while the rest of the students recorded an expected rate of success. A combination of IGD and complaints related to the prolonged fixation of the upper body in a specific viewing position was the best predictor variable set for future success in admission examinations. Conclusions: IGD is associated with a failure to achieve academic success. Combining a factor for physical discomfort during prolonged sessions of gaming with the typical criteria for IGD may expand the predictive validity of the construct of gaming disorder. [ABSTRACT FROM AUTHOR]

The use of the internet is a normative phenomenon associated with problems for younger people. The dysfunctional risks are those in which there is a problematic use of technologies that generates negative consequences. General Problematic Internet Use (GPIU) is the most prevalent, while Internet Gaming Disorder (IGD) and Online Gambling Disorder (OGD) are less prevalent, perhaps because they are Clinical problems and notably more severe. They have been widely studied separately but have hardly been examined conjointly and overlappingly. This study employs a sample with a broad age range including participants across the three stages of adolescence (early, middle, and late) and emerging adulthood. The objectives are to analyze: 1) the overall prevalence of GPIU, IGD and OGD; 2) the prevalence of GPIU, IGD and OGD according to the degree of the reported problem; 3) overlap of GPIU, IGD and OGD. These objectives will be carried out according to the variable sex and stages of adolescence. Cross-sectional and analytical study with 7,295 participants aged between 11 and 22 years. Considering risk, 13.8% of the participants had one or more risks; 11.5% presented at least one risk, 9.6% presented GPIU; 2% presented GPIU and IGD together; in only 0.1% did all three risks overlap. Girls present higher prevalence of GPIU, and boys of IGD, OGD and in all the overlaps. There is a general upward trend in middle and late adolescence versus early adolescence in these risks, which decline in emerging adulthood. These data are discussed concerning their importance in psychoeducational prevention and intervention actions. [ABSTRACT FROM AUTHOR]

The high level of technological growth in contemporary society, beside benefits, provokes different kinds of damages, especially among the worldwide youth population. World statistics have recognized that video and internet game addiction is a growing problem. In this context, it is supposed that 0.3 to 1.0 percent of the general population might be qualified as a potential sufferer of internet gaming disorder. However, youth between 18-34 years are the highest risk population. New research has shown the need of early identification of at-risk young people for internet addiction. Adverse experience in children of different forms of stress, negative life circumstances and especially negative, hostile parenting can lead to depression, social and cultural problems, together with significant boredom and loneliness levels. These are all confirmed to be related with addictive behaviour. Some neural correlates are discussed as the possible background of game addiction. Finally, therapeutic possibilities are presented. [ABSTRACT FROM AUTHOR]

Background and aims: COVID-19 lockdowns limited access to gambling but simultaneously elevated psychosocial stressors. This study assessed the relative effects of these changes on gambling risk status during and after the Australian COVID-19 lockdown from late-March to late-May 2020. Methods: The study administered three surveys to people who had gambled within the past year at T1. Wave 1 asked about before (T1, N 5 2,125) and during lockdown (T2, N 5 2,125). Subsequent surveys focused on one year (T3; N 5 649) and two years after lockdown (T4, N 5 458). The dependent variable was changes in reporting any problem gambling symptoms (PGSI 0 vs 1+). Bivariate analyses and multinomial logistic regression tested for significant associations with: demographics, psychosocial stressors (perceived stress, psychological distress, loneliness, health anxiety about COVID, financial hardship, stressful life events), gambling participation and gambling frequency. Results: Gambling participation and at-risk gambling decreased between T1 and T2, increased at T3, with little further change at T4. When gambling availability was curtailed, decreased gambling frequency on EGMs, casino games, sports betting or race betting, and lower psychosocial stress, were associated with transitions from at-risk to non-problem gambling. When gambling availability resumed, increased EGM gambling frequency, decreased online gambling frequency, and higher psychosocial stress were associated with transitions from non-problem to at-risk gambling. Discussion and conclusions: Gambling availability appears a stronger influence on gambling problems, at the population level, than psychosocial risk factors. Reducing the supply of high-risk gambling products, particularly EGMs, is likely to reduce gambling harm. [ABSTRACT FROM AUTHOR]

Background and aims: Smartphone, computer and land-based betting platforms each have distinctive features. This study examined 1) preferred features of sports betting platforms amongst young adults and 2) whether feature preferences vary with gambling severity. Methods: The study surveyed 616 Australians aged 18-29 years who bet at-least monthly on sports, esports and/or daily fantasy sports. Participants provided a simple rating of the importance of 24 features of betting platforms and then completed a discrete choice experiment to indicate their preferences amongst different groups of features. Results: Smartphones were the only platform providing all preferred features. The most important feature was ability to bet instantly 24/7 from any location, followed by electronic financial transactions. Less important features were ability to access betting information online and to bet with multiple operators. Social and privacy features, and access to promotions, did not significantly predict platform choice. The experiment found no significant differences in preferred features by gambling severity group or by gender. The non-experimental descriptive data, however, indicated that participants in the moderate risk/problem gambling categories placed significantly more importance on privacy, ability to place in-play bets, bet with cash, bet with a credit card, see frequent promotions, and bet with multiple operators. Discussion and conclusions: Most features that bettors prefer can intensify betting. Curtailment of betting promotions, in-play betting, and credit card betting are measures that can assist higher-risk gamblers without unduly affecting other gamblers. Consumer protection tools, including mandatory pre-commitment, need strengthening to help counter the unique risks of smartphone betting. [ABSTRACT FROM AUTHOR]

Introduction: The overall prevalence of gambling problems across prison populations is currently unknown. The objective of the present study was therefore to quantitatively synthetize prevalence estimates of gambling problems in prison populations using a random effects meta-analytic model and to investigate if the estimates were moderated by time frame, cut-off levels, and sample size. Methods: To be included the studies had to report original data on the prevalence of gambling problems in a prison sample and to be written in a European language, whereas data based on abstracts or qualitative reports were excluded. The search ended on December 1, 2023 and were conducted in Web of Science, PubMed, Cinahl, PsycINFO, Embase, Google Scholar, Grey Literature Report, and GreyNet. Risk of bias was assessed with a standardized 10-item measure for epidemiological studies. Results: A total of 26 studies comprising 9,491 participants were included. The vast majority of the participants were males. The most commonly used instrument for assessment of gambling problems was the South Oaks Gambling Screen. The pooled random-effects gambling problems prevalence estimate was 30.8% (95% CI 5 25.1-37.3). The meta-regression analysis showed that none of the three moderator variables (criteria, timeframe, sample size) were related to the gambling problems prevalence. Common limitations of the included studies entailed not being representative nationally or for the target population, lack of randomization, and low response rate. The meta-analysis was restricted to studies published in a European language. Conclusions: Overall, the studies show that 1 in 3 prisoners has gambling problems and suggests that more emphasis on relevant prevention and treatment is warranted for this population. The study was funded by the Norwegian Competence Center for Gambling and Gaming Research and pre-registered at PROSPERO (CRD42023390552). [ABSTRACT FROM AUTHOR]

Gambling Disorder (GD) is an impactful behavioural addiction for which there appear to be under-pinning genetic contributors. Twin studies show significant GD heritability results and intergenerational transmission show high rates of transmission. Recent developments in polygenic and multifactorial risk prediction modelling provide promising opportunities to enable early identification and intervention for at risk individuals. People with GD often have significant delays in diagnosis and subsequent help-seeking that can compromise their recovery. In this paper we advocate for more research into the utility of polygenic and multifactorial risk modelling in GD research and treatment programs and rigorous evaluation of its costs and benefits. [ABSTRACT FROM AUTHOR]

Gambling disorder is a severe mental health and behavioural problem with harmful consequences, including financial, relationship and mental health problems. The present paper initiates discussion on the use of psychedelics combined with psychotherapeutic support as a potential treatment option for people living with a gambling disorder. Recent studies have shown promising results using psychedelic-assisted therapy (PAT) to treat anxiety, depression, post-traumatic stress disorder, and various substance use disorders. Considering the similarities in the underlying psychosocial and neurobiological mechanisms of gambling disorder and other addictive disorders, the authors suggest that psychedelic-assisted therapy could be effective in treating gambling disorder. The paper also underscores the need for further research into the viability and effectiveness of psychedelic-assisted therapy for gambling disorder. [ABSTRACT FROM AUTHOR]

With the advent of digital technologies, online sports betting is spurring a fast‐growing expansion. In this study, we examined how sports betting availability modulates the brain connectivity of frequent sports bettors with [problem bettors (PB)] or without [non‐problem bettors (NPB)] problematic sports betting. We conducted functional connectivity analyses centred on the ventral anterior insular cortex (vAI), a brain region playing a key role in the dynamic interplay between reward‐based processes. We re‐analysed a dataset on sports betting availability undertaken in PB (n = 30) and NPB (n = 35). Across all participants, we observed that sports betting availability elicited positive vAI coupling with extended clusters of brain activation (encompassing the putamen, cerebellum, occipital, temporal, precentral and central operculum regions) and negative vAI coupling with the orbitofrontal cortex. Between‐group analyses showed increased positive vAI coupling in the PB group, as compared with the NPB group, in the left lateral occipital cortex, extending to the left inferior frontal gyrus, the anterior cingulate gyrus and the right frontal pole. Taken together, these results are in line with the central assumptions of triadic models of addictions, which posit that the insular cortex plays a pivotal role in promoting the drive and motivation to get a reward by 'hijacking' goal‐oriented processes toward addiction‐related cues. Taken together, these findings showed that vAI functional connectivity is sensitive not only to gambling availability but also to the status of problematic sport betting. [ABSTRACT FROM AUTHOR]

Gambling is commonly associated with social and economic disadvantage. In this paper we examine the impact of gambling on homeownership, using Australian panel data. We find that gambling is associated with a lower probability of homeownership. Specifically, our endogeneity corrected estimates show that an increase in problem gambling is associated with between 1.6 and 1.8 percentage point decrease in the probability of owning a home depending on the model. Our result show that financial stress and social capital are channels through which gambling influences the probability of homeownership. [ABSTRACT FROM AUTHOR]

Consistent evidence points to the detrimental effects of income inequality on population health. Income inequality may be associated with online gambling, which is of concern since gambling is a risk factor for adverse mental health conditions, such as depression and suicide ideation. Thus, the overall objective of this study is to study the role of income inequality on the odds of participating in online gambling. Data from 74,501 students attending 136 schools participating in the 2018/2019 Cannabis, Obesity, Mental health, Physical activity, Alcohol, Smoking, and Sedentary behaviour (COMPASS) survey were used. The Gini coefficient was calculated based on school census divisions (CD) using the Canada 2016 Census linked with student data. We used multilevel modeling to explore the association between income inequality and self-reported participation in online gambling in the last 30 days, while controlling for individual- and area-level characteristics. We examined whether mental health (depressive and anxiety symptoms, psychosocial wellbeing), school connectedness, and access to mental health programs mediate this relationship. Adjusted analysis indicated that a standardized deviation (SD) unit increase in Gini coefficient (OR = 1.17, 95% CI 1.05, 1.30) was associated with increased odds of participating in online gambling. When stratified by gender, the association was significant only among males (OR = 1.12, 95% CI 1.03, 1.22). The relationship between higher income inequality and greater odds for online gambling may be mediated by depressive and anxiety symptoms, psychosocial well-being, and school connectedness. Evidence points to further health consequences, such as online gambling participation, stemming from exposure to income inequality. [ABSTRACT FROM AUTHOR]

This study examined the roles of drug use disorder, neurotic health symptoms, and pathological smartphone use in COVID-19 lockdown–related stress. A sample of 288 young adults were purposively recruited. Data were collected using four standardized measures with robust psychometric properties: Cannabis Abuse Screening Test (CAST), the Smartphone Addiction Scale, COVID Stress Scale, and a Neuroticism subscale of the Big Five Inventory. The participants' ages ranged from 17 to 34 years, with a mean age of 24.09 (SD = 3.81) years. The hierarchical regression confirmed the hypotheses and results were consistent with expectations, F(3, 284) = 4.79, p <.05, such that 4.8% of the variance in COVID-19 lockdown stress was a result of the joint function of drug use disorder, neurotic health symptoms, and pathological smartphone use. Drug use disorder contributed to COVID-19 lockdown stress independently, whereas when merged with neuroticism, it did not predict outcome variable independently; the same was true for pathological smartphone use when entered into the third model. The preventive and control advocacy is a harm-reduction approach. Further empirical investigations of other predictors of COVID-19 lockdown stress, with a goal of initiating telebehavioral health interventions targeted at identifying and treating people with mental health needs—especially in times of global pandemic or movement restrictions—are recommended. [ABSTRACT FROM AUTHOR]

This article argues that video games can function as a critical platform from which to intervene into the conjunction between embodied experiences of racialisation and the production of race as a category within the cybernetic forms of identification of platform capitalism. Through analysis of the role played by race in video game cultures in Brazil, I explore both the affordances of video games and the limitations of their use in the fight against the specific forms that racism takes in the digital age. I carry out an in-depth analysis of two recent games, Dandara (2018) and Mandinga (2021), which both construct powerful critiques of "algorithmic racism" in Brazil, by focusing on the relationship between their representation of race at the levels of narrative, plot, and imagery and the ways in which the player interacts with the games' algorithms. While Dandara exploits tensions between the two to draw attention to the mix of authoritarian and "instrumentarian" (Zuboff) power in contemporary Brazil, Mandinga highlights parallels between its gameplay and the processes of racialisation to present algorithmic racism, which often goes unnoticed, as an act of violence that inherits some of the procedures of slavery and the social systems that perpetuated it. [ABSTRACT FROM AUTHOR]

Objectives: The Gambling Disorder Identification Test (GDIT) is a recently developed self‐report measure. The GDIT includes items with multiple response options that are either based on frequency or time, and item response theory evaluations of these could yield vital knowledge on its measurement performance. Methods: The GDIT was evaluated using Rasch analysis in a study involving 597 Swedish gamblers. Results: In a three‐dimensional Rasch model, the item response difficulty range extended from −1.88 to 4.06 and increased with higher time‐ and frequency‐based responses. Differential item functioning showed that some GDIT items displayed age and gender‐related differences. Additionally, person‐separation reliability indicated the GDIT could reliably be divided into three to four diagnostic levels. Conclusions: The frequency‐ and time‐based item response options of the GDIT offer excellent measurement, allowing for elaborate assessment across both lower and higher gambling severity. The GDIT can be used to detect DSM‐5 Gambling Disorder, thereby holding significance from both epidemiological and clinical standpoints. Notably, the 3‐item GDIT Gambling Behavior subscale also shows potential as a brief screening tool for identifying at‐risk gambling behavior. [ABSTRACT FROM AUTHOR]

Objective: This study protocol describes the RIGAB study, a prospective case‐control‐study assessing online sports betting behaviour and underlying risk factors for the development of gambling disorder (GD). It has two aims: (1) to characterise sports bettors concerning putative risk factors and their gambling behaviour, and (2) to predict the development of GD from these factors. Methods: At baseline, online sports bettors took part in an online survey comprising a GD screening (DSM‐5), questions on gambling behaviour and on the putative risk factors emotion regulation, impulsivity, comorbidities, stress, and substance use. Participants were reinvited for a 1‐year follow‐up online survey. In a nested design, a subsample was invited in‐person to take part in a cognitive‐behavioural task battery and a clinical interview. Results: Of the initial 6568 online sports bettors invited, 607 participated at baseline (rate: 9.2%), 325 took part in the 1‐year follow‐up and 54 participated in the nested in‐person assessment. Conclusion: The RIGAB study combines different fields of GD studies: player tracking data and putative risk factors from self‐report and behavioural tasks. The results of this study will support the development of preventive measures for participants of online gambling based on the combined findings from previously rather distinct research fields. [ABSTRACT FROM AUTHOR]

Excessive choice of smaller-immediate rewards has been positively correlated with a host of negative health outcomes such as addiction, gambling, and overeating. Meta-analytic research suggests that stress is a contextual variable that can contribute to impulsive choice. The strength of the relationship between stress and impulsive decision making may be largely moderated by how these variables are measured. Despite clinical relevance, the relationship between daily stress and decision making is not well understood. The current investigation sought to further characterize the relationship between acute stress and impulsive decision making using the Daily Stress Inventory and the 27-item Monetary Choice Questionnaire. Results from 69 adults revealed a positive correlation between daily stressors and impulsive decision making. Future directions are discussed aimed at experimental evaluations of the effects of stress on impulsive decision making. [ABSTRACT FROM AUTHOR]

This paper offers a systematic review of quantitative and qualitative studies on the main twelve-step mutual-help (TSMH) groups (excluding Alcoholics Anonymous) and four meta-analyses exploring the correlation between (i) duration or involvement in TSMH groups and; (ii) severity of symptoms or quality of life. Systematic review was conducted following PRISMA guidelines. Searches of databases (MEDLINE, PsychInfo), a register (ClinicalTrials) and citations were conducted, from inception through November 01 2022. Fifty five articles were included (24 quantitative, 27 qualitative, 4 mixed-methods), corresponding to 47 distinctive studies. 68% of these studies were conducted in North America, 17% in Middle East, 11% in the European Union and 4% in Australia. The most studied TSMH group were Gamblers Anonymous (28% of the 47 studies), Narcotics Anonymous (26%), Double Trouble in Recovery (15%), Overeaters Anonymous (19%) and TSMH groups for compulsive sexual behaviors (11%). The four meta-analyses pooled data from 9 studies. Pooled mean age ranged from 36.5 to 40.5. 80–81% of participants were male. TSMH attendance and involvement were negatively correlated with severity of symptoms (high and medium levels of evidence) and positively correlated with quality of life (low levels of evidence). Twenty-one qualitative papers reported factors influencing recovery: Social (n = 15), emotional (n = 9), spiritual (n = 8), self-identification or psychological (n = 6) factors. Review provides characteristics of TSMH groups others than Alcoholics Anonymous, with implications for both research and healthcare practice. The perspective to implement TSMH groups targeting ontological addiction, at the root of all addiction, is discussed. Protocol registration: Prospero registration number: CRD42022342605. [ABSTRACT FROM AUTHOR]

This study focused on mothers and childless women in recovery from a gambling disorder (GD) in the context of risk society. Mothers with GD suffer from dual social stigma as gamblers and as women who put their children at risk. Mothers in "risk society" tend to recognize that their choices can affect their children's future. The recovery capital (RC) toolkit comprises internal and external resources and barriers enacted in recovery. This longitudinal study: (a) compared the RC toolkits of mothers versus childless women and their effects on these women's dropout and relapse rates; (b) explored the resources and barriers that predict dropout and relapse in each group. Analysis of the clinical data of 211 women with GD (N = 146 mothers) who received cognitive behavioral therapy for 16 weeks in Spain indicated that mothers reported lower levels of education and were from more disadvantaged socioeconomic groups, were older, and developed gambling-related problems in older age. Mothers had significantly lower relapse rates but not lower dropout rates. There were more personal predictors of dropout among childless women, whereas low levels of family support and the absence of gambling debts predicted dropout in the mothers' group. These findings were interpreted by combining the concepts of risk society and recovery capital in action, highlight the differences between resources and barriers in the RC toolkits used by mothers versus childless women and their interplay with the sociocultural contexts of risk society and childfree lifestyles. Therapists and policymakers should consider these differences during recovery. Public Policy Relevance Statement: Women with gambling disorders cope with multiple challenges during their recovery, especially if they are also mothers. This study compared and examined mothers' versus childless women's recovery capital toolkits and their effect on dropout and relapse rates. The differences between the two are interpreted by the interplay between these toolkits and the sociocultural contexts that mothers and childless women encounter in their daily lives. Policymakers and therapists should consider these contexts and the ways they may enhance or hinder women's recovery from gambling disorder. [ABSTRACT FROM AUTHOR]

This study was conducted as a descriptive and cross‐sectional study to examine the effects of game addiction and social media addiction on the lifestyle of Turkish adolescents. The study was conducted between May to June 2022, involved 1116 adolescents in the 13−18 age group receiving education in three high schools situated in the Western region of Turkey. Data were collected online with the Descriptive Information Form, Game Addiction Scale Short Form for Adolescents (GAS), Social Media Addiction Scale for Adolescents (SMAS), and Adolescent Lifestyle Profile Scale (ALP). Mean, percentage, t test, analysis of variance and linear regression analysis were used for analyzing data. There was a statistically significant difference between the presence of social media accounts and smartphones, duration of having social media account, average time spent daily on social media accounts and virtual games, social media use characteristics for the last 6 months, interests of influencers followed on social media, affection by influencers, and effect of social media on daily life and the mean scores on GAS, SMAS, and ALP. It was determined that game addiction and social media addiction explained 61.8% of the lifestyles of adolescents and significantly affected them. In addition, social media use characteristics, game addiction, and social media addiction explain and significantly predict the lifestyle of adolescents at a rate of 62.8%. The results of the study reveal that game addiction and social media addiction is a significant predictor of Turkish adolescents' lifestyle. It can be recommended to provide trainings that shed light on the importance of efficient use of technology to adolescents and their parents and to evaluate the effectiveness of these trainings. Practitioner points: The game and social media addiction and social media use characteristics affect the mean adolescent lifestyle scores.Health professionals and school workers should collaborate with professionals from various disciplines and plan training to promote healthy use of the internet and smartphones.It is necessary to determine the causes and addiction levels of social media use and online gaming in future comprehensive studies. [ABSTRACT FROM AUTHOR]

Gambling Disorder (GD) is characterised by a harmful, enduring, and recurrent involvement in betting-related behaviours. Therefore, GD shares similar biological mechanisms and symptoms to substance use disorders (SUD). Therefore, in this study, we chose the behavioural addictions group. During the examination and recruitment to the study, it turned out that all the people undergoing treatment for gambling addiction were also addicted to amphetamines, which is consistent with the biological mechanism related to cerebral neurotransmission. The aim of the study was to investigate the association of the COMT gene polymorphism with behavioral addiction. The study group consisted of 307 participants: 107 men with gambling disorder and amphetamine dependency (mean age = 27.51, SD = 5.25) and 200 non-addicted, nor dependent, free from neuro-psychiatric disorders control group men (mean age = 20.20, SD = 4.51). Both groups were subjected to psychometric evaluation using the State-Trait Anxiety Inventory and the NEO Five-Factor Personality Inventory. Genomic DNA was extracted from venous blood following standard protocols. Determination of the rs4680 polymorphism in the COMT gene was performed using the real-time PCR technique. Statistically significant differences in the frequency of rs4680 genotypes were found in the tested sample of subjects compared with the control group (p = 0.03543). Subjects with gambling disorder and amphetamine use disorder compared to the control group obtained higher scores in the assessment of the STAI trait scale (p = 0.0019), state scale (p < 0.0000), and NEO-FFI Neuroticism scale (p < 0.0000). Significantly lower results were obtained for the NEO-FFI Agreeability scale (p < 0.0000). Additionally, a significant statistical impact of gambling disorder and amphetamine use disorder, and the COMT rs4680 genotype was demonstrated for the score of the STAI trait (p = 0.0351) and state (p = 0.0343) and the NEO-FFI Conscientiousness scale (p = 0.0018). We conclude that COMT and its polymorphic variant influence the development of addiction. Still, considering its multifactorial and polygenic nature, it should be combined with other factors such as personality. [ABSTRACT FROM AUTHOR]

In this paper, we explore a model of an N-player, non-cooperative stochastic game, drawing inspiration from the discrete formulation of the red-and-black gambling problem, as initially introduced by Dubins and Savage in 1965. We extend upon the work of Pontiggia from 2007, presenting a main theorem that broadens the conditions under which bold strategies by all players can achieve a Nash equilibrium. This is obtained through the introduction of a novel functional inequality, which serves as a key analytical tool in our study. This inequality enables us to circumvent the restrictive conditions of super-multiplicativity and super-additivity prevalent in the works of Pontiggia and others. We conclude this paper with a series of illustrative examples that demonstrate the efficacy of our approach, notably highlighting its ability to accommodate a broader spectrum of probability functions than previously recognized in the existing literature. [ABSTRACT FROM AUTHOR]