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Your search keyword '"Álvarez-Dobaño, José M."' showing total 25 results
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4. Response to inhaled ceftazidime in patients with non‐cystic fibrosis bronchiectasis and chronic bronchial infection unrelated to Pseudomonas aeruginosa

Author

Riveiro, Vanessa, primary, Casal, Ana, additional, Álvarez‐Dobaño, José M., additional, Lourido, Tamara, additional, Suárez‐Artime, Pedro, additional, Rodríguez‐García, Carlota, additional, Ferreiro, Lucía, additional, Toubes, María E., additional, and Valdés, Luis, additional

Published
2022
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5. Characteristics of pleural effusion due to amyloidosis.

Author

Pou, Cristina, Ferreiro, Lucía, Suárez-Antelo, Juan, Golpe, Antonio, Álvarez-Dobaño, José M., Toubes, María Elena, Lama, Adriana, Rodríguez-Núñez, Nuria, Ricoy, Jorge, Rábade, Carlos, Lourido, Tamara, and Valdés, Luis

Subjects
AMYLOIDOSIS diagnosis, ONLINE information services, AMYLOIDOSIS, PLEURAL effusions, ADRENOCORTICAL hormones, SYSTEMATIC reviews, PLEURODESIS, DYSPNEA, SYMPTOMS, DESCRIPTIVE statistics, MEDLINE, DATA analysis software, DISEASE complications
Abstract

The characteristics of patients with pleural amyloidosis (PA) are poorly known. A systematic review was performed of studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of PA. Case descriptions and retrospective studies were included. The review included 95 studies with a total sample of 196 patients. The mean age was 63 years, male/female ratio was 1.6:1, and 91.9% of patients were >50 years. The most common symptom was dyspnea (88 patients). PF was generally serious (63%), predominantly lymphocytic, and with the biochemical characteristics of transudates (43.4%) or exudates (42.6%). Pleural effusion was generally bilateral (55%) and <1/3 of the hemithorax (50%), although in 21% pleural effusion (PE) exceeded 2/3. Pleural biopsy was performed in 67 patients (yield: 83.6%; 56/67) and was positive in 54% of exudates and 62.5% of unilateral effusions. Of the 251 treatments prescribed, only 31 were effective (12.4%). The combination of chemotherapy and corticosteroids was effective in 29.6% of cases, whereas talc pleurodesis was effective in 21.4% and indwelling pleural catheter in 75% of patients (only four patients). PA is more frequent in adults from 50 years of age. PF is usually bilateral, serous, and indistinctly a transudate or exudate. A pleural biopsy can aid in diagnosis if effusion is unilateral or an exudate. Treatments are rarely effective and there may be definitive therapeutic options for PE in these patients. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Evaluation of the impact of an integrated care pathway for pulmonary embolism: a quasi-experimental pre-post study

Author

Rodríguez-Núñez, Nuria, primary, Ruano-Raviña, Alberto, additional, Lama, Adriana, additional, Ferreiro, Lucía, additional, Ricoy, Jorge, additional, Álvarez-Dobaño, José M., additional, Suárez-Antelo, Juan, additional, Toubes, M. Elena, additional, Rábade, Carlos, additional, Golpe, Antonio, additional, Riveiro, Vanessa, additional, Casal, Ana, additional, Abelleira, Romina, additional, González-Barcala, Francisco Javier, additional, González-Juanatey, José R., additional, and Valdés, Luis, additional

Published
2021
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16. Impact of cardiovascular risk factors on the clinical presentation and survival of pulmonary embolism without identifiable risk factor

Author

Rodríguez-Núñez, Nuria, primary, Ruano-Raviña, Alberto, additional, Lama, Adriana, additional, Ferreiro, Lucía, additional, Ricoy, Jorge, additional, Álvarez-Dobaño, José M., additional, Suárez-Antelo, Juan, additional, Toubes, M. Elena, additional, Rábade, Carlos, additional, Golpe, Antonio, additional, Lourido, Tamara, additional, González-Barcala, Francisco Javier, additional, and Valdés, Luis, additional

Published
2020
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17. Urinothorax: a systematic review

Author

Toubes, María E., primary, Lama, Adriana, additional, Ferreiro, Lucía, additional, Golpe, Antonio, additional, Álvarez-Dobaño, José M., additional, González-Barcala, Francisco J., additional, San José, Esther, additional, Rodríguez-Núñez, Nuria, additional, Rábade, Carlos, additional, Lourido, Tamara, additional, and Valdés, Luis, additional

Published
2017
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18. Predictive models of malignant transudative pleural effusions

Author

Ferreiro, Lucía, primary, Gude, Francisco, additional, Toubes, María E., additional, Lama, Adriana, additional, Suárez-Antelo, Juan, additional, San-José, Esther, additional, González-Barcala, Francisco Javier, additional, Golpe, Antonio, additional, Álvarez-Dobaño, José M., additional, Rábade, Carlos, additional, Rodríguez-Núñez, Nuria, additional, Díaz-Louzao, Carla, additional, and Valdés, Luis, additional

Published
2017
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19. Characteristics of patients with pseudochylothorax—a systematic review

Author

Lama, Adriana, primary, Ferreiro, Lucía, additional, Toubes, María E., additional, Golpe, Antonio, additional, Gude, Francisco, additional, Álvarez-Dobaño, José M., additional, González-Barcala, Francisco J., additional, José, Esther San, additional, Rodríguez-Núñez, Nuria, additional, Rábade, Carlos, additional, Rodríguez-García, Carlota, additional, and Valdés, Luis, additional

Published
2016
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20. Predicting malignant and tuberculous pleural effusions through demographics and pleural fluid analysis of patients

Author

Valdés, Luis, primary, San-José, Esther, additional, Ferreiro, Lucía, additional, Golpe, Antonio, additional, González-Barcala, Francisco-Javier, additional, Toubes, María E., additional, Rodríguez-Álvarez, María X., additional, Álvarez-Dobaño, José M., additional, Rodríguez-Núñez, Nuria, additional, Rábade, Carlos, additional, and Gude, Francisco, additional

Published
2014
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21. Role of Blind Closed Pleural Biopsy in the Management of Pleural Exudates

Author

Pereyra, Marco F, primary, San-José, Esther, additional, Ferreiro, Lucía, additional, Golpe, Antonio, additional, Antúnez, José, additional, González-Barcala, Francisco-Javier, additional, Abdulkader, Ihab, additional, Álvarez-Dobaño, José M, additional, Rodríguez-Núñez, Nuria, additional, and Valdés, Luis, additional

Published
2013
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22. Recent epidemiological trends in tuberculous pleural effusion in Galicia, Spain

Author

Valdés, Luis, primary, Ferreiro, Lucía, additional, Cruz-Ferro, Elena, additional, González-Barcala, Francisco J., additional, Gude, Francisco, additional, Ursúa, María I., additional, Álvarez-Dobaño, José M., additional, Golpe, A., additional, Toubes, María E., additional, Paniagua, José, additional, Taboada-Rodríguez, José A., additional, and Soriano, Joan B., additional

Published
2012
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24. Diagnosing tuberculous pleural effusion using clinical data and pleural fluid analysis A study of patients less than 40 years-old in an area with a high incidence of tuberculosis

Author

Valdés, Luis, San José, Ma Esther, Pose, Antonio, Gude, Francisco, González-Barcala, Francisco J., Álvarez-Dobaño, José M., and Sahn, Steven A.

Subjects
Diagnosis, nutritional and metabolic diseases, Tuberculosis, Pleural effusion
Abstract

SummaryBackgroundTuberculous pleural effusions (TPE) are common. The diagnosis is often problematic. As the determination of ADA is often unavailable in some countries, the aim of this study was to evaluate the diagnostic usefulness of other data from pleural fluid analysis, in young patients from populations with high prevalence of tuberculosis (TB).MethodsWe analysed 218 patients with pleural effusion (165 tuberculous, 21 infectious, 11 neoplastic, 16 miscellaneous, 3 idiopathic). We performed two regression models; one included pleural fluid ADA values (model 1), and the other without ADA (model 2).ResultsModel 1 selected two variables (ADA >35U/L) and lymphocytes (>31.5%) and correctly classified 216/218 effusions (1 false negative, 1 false positive). Model 2 (without ADA) selected three variables: lymphocytes (>31.5%), fever and cough, and correctly classified 207/218 effusions (8 false negatives, 3 false positives). The sensitivity of models 1 and 2 was 99.4% and 95.2%, specificity 98.1% and 94.3% and accuracy 99% and 95%.ConclusionsIn geographic areas with high prevalence of TB and a low prevalence of HIV, in young patients (≤40 years), it is possible to confidently diagnose TPE with either of the two regression tree models, with the utility of ADA providing superior sensitivity, specificity, and accuracy.

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25. Interleukin 27 could be useful in the diagnosis of tuberculous pleural effusions.

Author

Valdés L, San José E, Ferreiro L, Golpe A, Gude F, Álvarez-Dobaño JM, Pereyra MF, Toubes ME, and González-Barcala FJ

Subjects
Adenosine Deaminase analysis, Adolescent, Adult, Aged, Aged, 80 and over, Extravascular Lung Water chemistry, Female, Humans, Interferon-gamma analysis, Male, Middle Aged, Pleural Effusion etiology, Prospective Studies, ROC Curve, Sensitivity and Specificity, Tuberculosis, Pleural complications, Young Adult, Interleukin-27 analysis, Pleural Effusion diagnosis, Tuberculosis, Pleural diagnosis
Abstract

Background: The diagnosis of tuberculous pleural effusion (TBPE) has some limitations. We studied the efficacy of interleukin-27 (IL-27) in the diagnosis of TBPE., Methods: We measured IL-27, adenosine deaminase (ADA), ADA-2, interferon-gamma (IFNγ), and the ADA·IL-27 and ADA-2·IL-27 products in all the pleural effusion fluids. The diagnostic yield of IL-27 was evaluated with receiver operating characteristic curves., Results: Of 431 pleural effusions, 70 were tuberculous, 146 were neoplastic, 58 were parapneumonic, 28 were empyemas, 88 were transudates, and 41 were other types. With a cutoff point of 0.55 ng/mL, IL-27 had a sensitivity of 91.4% and a specificity of 85.1%, which were significantly less than ADA, ADA-2, IFNγ, ADA·IL-27, or ADA-2·IL-27. The area under the receiver operating characteristic curve for IL-27 (0.963) was also significantly lower than that for the other markers, except for IFNγ. However, IL-27 improved the sensitivity of ADA and ADA-2 through ADA·IL-27 and ADA-2·IL-27 products (100% for both)., Conclusions: IL-27 is less efficient than ADA and ADA-2 in the diagnosis of TBPE. However, ADA·IL-27 and ADA-2·IL-27 improve the diagnostic sensitivity of ADA and ADA-2, and thus could be useful in situations of high clinical suspicion and low ADA level. A value above the cutoff point of the latter is practically diagnostic of TBPE.

Published
2014
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