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Objective: Hypersensitivity reactions to beta-lactams are often reported in children. Although many of these children are considered to be allergic, a careful evaluation only confirms a low percentage. The aim of this study was to evaluate the clinical data and diagnostic methods used in children with a clinical history of hypersensitivity reactions to betalactams. Material and Methods: The medical records of patients presenting with suspected beta-lactam allergy were evaluated retrospectively between June 2013 to December 2015 at the Dokuz Eylul University's Department of Pediatric Allergy and Immunology. results: In total, data of 33 patients were obtained from medical records. Only 5 (13.8%) of the patients had an allergy. Skin prick test, intradermal test and oral provocation test (OPT) were administered to 15 (45.4%) patients and 3 of the patients were diagnosed as having hypersensitivity to culprit drugs (1 amoxicillin, 1 cefuroxime and 1 both cefuroxime and ampicillin). A total of 18 patients with non-immediate cutaneous reactions without systemic symptoms were administered penicilloyl G- and V-specific immunoglobulin E (IgE) and OPT and 2 patients were diagnosed as having isolated clavulanic acid allergy. conclusion: Beta-lactam allergies could be overdiagnosed and a careful evaluation should be performed for accurate diagnosis. For children with non-immediate cutaneous reactions, OPTs are safe and effective. [ABSTRACT FROM AUTHOR]

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Foreign body aspiration is an important cause of emergency admission in children younger than 3 years old. Patients may manifest with cough, acute respiratory distress, wheezing and stridor or may be asymptomatic. History, physical examination, radiological imaging and bronchoscopy are used for diagnosis. Subcutaneous emphysema and pneumomediastinum can be seen as complications of bronchoscopy but it is very rare for the foreign body itself to cause these complications. Herein we present a case who was admitted to emergency service because of swelling of the neck due to subcutaneous emphysema, as a rare complication of foreign body aspiration. [ABSTRACT FROM AUTHOR]

Cross-reactivity has important consequences in some immune disorders, including allergic and autoimmune diseases, which can affect both diagnostic and therapeutic approaches. One of the most common cross-reactivity syndromes is pollen-food syndrome (PFS). The patient is sensitized with pollen by the airways and exhibits an allergic reaction to food antigen with a structural similarity to the pollen. PFS usually presents with pruritus and swelling of the mouth and throat during or just after ingestion of fresh, uncooked fruits and vegetables. Latex fruit syndrome is another cross-reactivity syndrome. It is the association of latex allergy and allergy to plant foods, which affects up to 50% of latex-allergic patients. Here, we present two cases with crossreactivity syndrome. [ABSTRACT FROM AUTHOR]

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of the Turkish Dermatology & Venerology / Turkderm is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Urticaria can be induced with a wide variety of environmental stimuli, such as cold, pressure, vibration, sunlight, exercise, temperature changes, heat, and water. Urticaria caused by physical factors has been reported as the cause of 6-17% of the chronic urticaria in children. We present three cases here - cholinergic, cold and aquagenic urticaria - in which the diagnosis was proven with exercise, ice-cube and water provocation tests, respectively. [ABSTRACT FROM AUTHOR]

A 33 weeks' gestation, a baby with rhesus hemolytic disease (RHD), who had received intrauterine transfusions twice, developed cholestatic hepatic disease and late hyporegenerative anemia. Her serum ferritin and bilirubin levels increased to 8842 ng/ml and 17.9 mg/dl, respectively. Liver biopsy showed cholestasis and severe iron overload. Treatment with recombinant erythropoietin (rHuEPO) decreased the transfusion need, and intravenous deferoxamine resulted in a marked decreased in serum ferritin levels and normalization of liver function. In patients who have undergone intrauterine transfusions due to RHD, hyperferritinemia and late hyporegenerative anemia should be kept in mind. Chelation therapy in cases with symptomatic hyperferritinemia and rHuEPO treatment in cases with severe hyporegenerative anemia should be considered.