21 results on '"Çok G"'
Search Results
2. The contribution of fluorine 18F-FDG PET/CT to lung cancer diagnosis, staging and treatment planning [Flor18F-FDG PET/BT’nin akciğer kanseri tanı, evreleme ve tedavi planlamasına katkısı]
- Author
-
Budak E., Çok G., Akgün A., and Ege Üniversitesi
- Subjects
Positron emission tomography ,Lung cancer ,Survival analysis - Abstract
Objective: Lung cancer is the most common cause of cancer-related death throughout the world, and the correct choice of treatment based on early diagnosis and staging increases the chance of survival. The present study aims to investigate the contribution of fluorine 18-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG PET/CT) to the management of lung cancer. Methods: In this study, 50 patients who underwent 18F-FDG PET/CT for lung cancer diagnosis and staging between February 2012 and February 2014 were included. The maximum standardized uptake value (SUVmax) of the primary lung lesion along with other findings of 18F-FDG PET/CT and the results of histopathologic and conventional examinations were evaluated retrospectively. The mean survival time of patients was determined, and the findings were compared by using statistical methods. Results: Histopathologic examinations revealed 51 lung cancers in 50 patients. The sensitivity, accuracy and positive predictive value of 18F-FDG PET/CT in detecting primary malignancy were 94%, 94%, 100%, respectively. Adenocarcinoma (n=23, 16.8±13.5) and squamous cell carcinoma (n=15, 17.9±5.6) did not differ significantly regarding their mean SUVmax values (p=0.2). A statistically significant positive correlation (r=0.4) was identified between tumor size and SUVmax value for 51 tumors (p=0.002). The 18F-FDG PET/CT result was true negative in nine, false positive in six, true positive in two, and false negative in four patients who underwent histopathologic evaluation of their lymph nodes. The 18F-FDG PET/CT changed treatment planning in 34% of the patients. No significant relationship was identified between SUVmax value of the tumor and patient survival in patients (p=0.118). Conclusion: The present study concluded that PET/CT was an efficient method in the diagnosis and staging of lung cancer since it provided useful information in addition to conventional methods. It was also observed that PET/CT scanning resulted in a change in therapeutic plans in the majority of patients. However, there was no statistically significant relationship between survival and the SUVmax of the primary mass. © 2018 by Turkish Society of Nuclear Medicine Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.
- Published
- 2018
3. Diagnostic yield of bronchoscopy with C-arm scopy in cases without endobronchial lesion [Endobronşiyal lezyon saptanmayan olgularda C kollu skopi eşliğinde yapılan bronkoskopinin tanı değeri]
- Author
-
Emre J.Ç., Baysak A., Öz A.T., Çok G., Göksel T., and Ege Üniversitesi
- Subjects
C-arm scopy ,Tumor ,Peripheral pulmonary lesion ,Bronchoscopy ,Diagnosis - Abstract
Aim: Fiberoptic bronchoscopy (FOB) is widely used in the diagnosis and treatment of pulmonary diseases. FOB sensitivity is generally low in tumors localized in the outer third of the lung. Diagnosis of peripheral pulmonary lesions can be difficult; however, the use of computed tomography (CT)-, fluoroscopy- or ultrasonography (USG)-guided surgery increases the diagnostic rates. In this study we aimed to compare the diagnostic values of C-arm fluoroscopy-guided bronchoscopic lavage, brushing, and biopsy samples obtained in cases where radiological masses or parenchymal lesions were detected, but endobronchial pathology was not found. Material and Method: In this prospective observational study, bronchoscopy was performed to the patients who had a mass lesion or parenchymal infiltration on chest radiogram and who had no endobronchial lesion, the diagnostic results of the bronchoscopic lavage, brush and biopsy specimens have been compared where C-arm scopy guided the procedures. Results: 60 patients (45 male) with a mean age 61.5±9.6 were enrolled into the study. The lesions were mostly located in the right upper lobe. 45 patients had peripheral mass lesion, 17 patients had noduler lesion where consolidation or infiltration were present in 18 patients. The diagnostic yield of the bronchoscopic biopsy was 36%, brushing 20% and 21% for the bronchoscopic lavage. Overall diagnostic yield with all bronchoscopic methods was 45%. In lesions with a diameter of
- Published
- 2016
4. Expression of p63, TTF–1 and Maspin in non-small cell lung carcinoma and their effect on the prognosis and differential diagnosis [Küçük hücreli dişi akciğer karsinomunda p63, TTF-1 ve maspin ekspresyonu - Prognoz ve ayırıcı tanı üzerine etkileri]
- Author
-
Yaman B., Nart D., Korkmaz Ekren P., Çok G., Veral A., and Ege Üniversitesi
- Subjects
P63 ,ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS ,ComputingMethodologies_PATTERNRECOGNITION ,TTF-1 ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Maspin ,Non-small-cell lung carcinoma ,InformationSystems_MISCELLANEOUS ,Prognosis - Abstract
PubMed ID: 26456962, Objective: Lung cancer is still the leading cause of cancer mortality. Antiapoptotic genes and protease inhibitors play an important role in the development of lung cancer. Material and Method: p63, TTF-1 and maspin expression and their role in the differential diagnosis, overall survival, progression-free survival and other clinicopathological characteristics of the patients were investigated in 80 surgically-resected non-small cell lung carcinomas. Results: The maximal tumor diameter range was 1.5–11 cm (mean: 4.06±1.8 cm). Forty-five (56.3%) tumors were adenocarcinoma, 23 (28.8%) squamous cell carcinoma, four (5%) large cell carcinoma, six (7.5%) large cell neuroendocrine carcinoma, one (1.2%) sarcomatoid carcinoma while one was (1.2%) both adenocarcinoma and squamous cell carcinoma. The patients with advanced TNM stage and a tumor diameter more than 3 cm had markedly poor survival. Immunohistochemically, p63 staining was present in 87.5% of squamous cell carcinomas, 4.3% of adenocarcinomas, 25% of large cell carcinomas, and 16.7% of large cell neuroendocrine carcinomas. Similarly, maspin was positive in 66.7% of squamous cell carcinomas and 17.4% of adenocarcinomas. The TTF–1 staining rate was higher in adenocarcinomas (84.8%). There was no immunoreactivity in squamous cell carcinomas (p0.05) while maspin has a negative prognostic effect in adenocarcinoma (p=0.048). Conclusion: This study suggests that p63 and TTF–1 are reliable markers in non-small cell lung carcinoma and can be used in differential diagnosis. Maspin has been identified as a prognostic marker in adenocarcinoma. However, more studies are required to elucidate the significance of maspin. © 2015, Federation of Turkish Pathology Societies. All rights reserved.
- Published
- 2015
5. Prevalence and seasonal distribution of respiratory viruses in patients with acute respiratory tract infections, 2002-2014 [Akut Solunum Yolu Enfeksiyonu Olan Hastalarda Solunum Viruslarinin Prevalansi ve Mevsimsel Da?ilimi, 2002-2014]
- Author
-
Çiçek C., Arslan A., Karakuş H.S., Yalaz M., Saz E.U., Pullukçu H., Çok G., and Ege Üniversitesi
- Subjects
ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS ,Respiratory viruses ,ComputingMethodologies_PATTERNRECOGNITION ,Epidemiology ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Prevalence ,InformationSystems_MISCELLANEOUS ,Respiratory tract infections - Abstract
PubMed ID: 26167819, The aim of this study was to investigate the prevalence and seasonal distribution of respiratory viruses in pediatric and adult outpatients and inpatients who were admitted to hospital with the symptoms of upper and lower respiratory tract infections, during a 12-year period. A total of 5102 clinical samples (4372 nasopharyngeal swabs, 316 bronchoalveolar lavages, 219 transtracheal aspirates, 163 nasopharyngeal aspirates, 20 sputum, 10 nasal swabs) examined in our laboratory between January 1st 2002 and July 17th 2014, were evaluated retrospectively. Of the specimens, 1107 (21.7%) were obtained from outpatients and 3995 (78.3%) from hospitalized patients. Of the patients, 2851 (55.9%) were male and 2251 (44.1%) were female, while 1233 (24.2%) were adults and 3869 (75.8%) were children (age range: 1 day - 93 years; median: 3 years). Respiratory samples were investigated for the presence of respiratory syncytial virus (RSV), influenza virus type A and B (INF-A, INF-B), adenovirus (AdV), parainfluenza viruses (PIV types 1-4), human rhinoviruses (HRV), human coronaviruses (HCoV), human metapneumovirus (HMPV) and human bocavirus (HBoV). All specimens were tested by both direct immunofluorescence antibody (DFA) and shell vial cell culture (SVCC) methods. In DFA assay the samples were initially screened by fluorescent-labeled polyclonal antibodies, and the positive ones were typed by using monoclonal antibodies (Light Diagnostics, Merck Millipore, USA). In SVCC, HEp-2, MDCK, A-549 and Vero cell lines were used for the isolation of viruses. In addition to these methods, real-time multiplex PCR methods (RealAccurate®, Respiratory RT PCR, PathoFinder, Netherlands and Seeplex® RV15 ACE Detection, Seegene, South Korea) were used for the detection of respiratory viruses in samples (n= 2104) obtained from 2007 to 2014. Respiratory viruses were detected in a total of 1705 (33.4%) patients, of them 967 (19%) were male and 738 (14.4%) were female. Three hundred and eighteen (18.6%) of the 1705 patients were infected with multiple respiratory viruses. The most frequently observed co-infections were RSV+INF-A (40/318; 12.6%), and RSV+PIV (33/318; 10.4%). The rate of positivity for the respiratory viruses in pediatric and adult groups were 35.4% (1369/3869) and 27.3% (336/1233), respectively (p< 0.000). The most frequently detected virus in pediatric group was RSV (336/1369;24.5%), followed by influenza viruses (314/1369;22.9%), PIV (197/1369;14.4%), HRV (118/1369;8.6%), AdV (75/1369;5.5%) and the others (49/1369;3.6%). On the other hand the most frequently detected virus in adult group was influenza viruses (181/336; 53.8%) followed by AdV (37/336; 11%), RSV (24/336; 7.1%), PIV (24/336; 7.1%), HRV (23/336; 6.8%) and the others (9/336; 2.7%). The rate of multiple virus infections in pediatric and adult groups were 7.2% (280/3869) and 3% (38/1233), respectively. Most of the coinfections (280/318; 88%) were detected in children. Respiratory viruses were detected positive in 40.2% (445/1107) of outpatients, and in 31.5% (1260/3995) of inpatients (p< 0.000). The most frequent viruses detected in pediatric outpatients and inpatients were HRV and RSV, respectively, while influenza viruses were the first in line among both adult outpatients and inpatients. During the study period, a PIV-3 outbreak (n= 96) have emerged between December 2004-April 2005, and an influenza A (H1N1)pdm09 outbreak (n= 207) between November 2009-January 2010. When the seasonal distribution was considered, the isolation rates of 1705 respiratory viruses in winter, spring, summer and autumn were 44.4%, 27%, 8.3% and 20.3%, respectively. RSV was most frequently detected from December to March, influenza viruses from November to March, HRV from December to June, and mixed infections from January to February. In conclusion, the data of our study obtained in about 12-year period indicated that the prevalence of respiratory viruses in acute respiratory infections is 33.4%, and they typically active during the months of winter and early spring in our region.
- Published
- 2015
6. Simultaneous detection of respiratory viruses and influenza a virus subtypes using multiplex PCR [Solunum Viruslari ve ¯nfluenza A Virus Alt Tiplerinin Multipleks PCR Yöntemi ile Ayni Anda Saptanmasi]
- Author
-
Çiçek C., Bayram N., Anil M., Gülen F., Pullukçu H., Saz E.U., Telli C., Çok G., and Ege Üniversitesi
- Subjects
ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS ,ComputingMethodologies_PATTERNRECOGNITION ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Respiratory vimses ,Subtype ,InformationSystems_MISCELLANEOUS ,Multiplex PCR ,Influenza virus type A - Abstract
PubMed ID: 25492660, This study was conducted to investigate the respiratory viruses and subtyping of influenza A virus when positive by multiplex PCR in patients with flu-like symptoms, after the pandemic caused by influenza A (H1N1)pdm09. Nasopharyngeal swab samples collected from 700 patients (313 female, 387 male; age range: 24 days-94 yrs, median age: 1 yr) between December 2010 - January 2013 with flu-like symptoms including fever, headache, sore throat, rhinitis, cough, myalgia as defined by the World Health Organization were included in the study. Nucleic acid extractions (Viral DNA/RNA Extraction Kit, iNtRON, South Korea) and cDNA synthesis (RevertAid First Strand cDNA Synthesis Kits, Fermentas, USA) were performed according to the manufacturer's protocol. Multiplex amplification of nucleic acids was performed using DPO (dual priming oligonucleotide) primers and RV5 ACE Screening Kit (Seegene, South Korea) in terms of the presence of influenza A (INF-A) virus, influenza B (INF-B) virus, respiratory syncytial virus (RSV), and the other respiratory viruses. PCR products were detected by automated polyacrylamide gel electrophoresis using Screen Tape multiple detection system. Specimens which were positive for viral nucleic acids have been further studied by using specific DPO primers, FluA ACE Subtyping and RV15 Screening (Seegene, South Korea) kits. Four INF-A virus subtypes [human HI (hH1), human H3 (hH3), swine HI (sHI), avian H5 (aH5)] and 11 other respiratory viruses [Adenovirus, parainfluenza virus (PIV) types 1-4, human bocavirus (HBoV), human metapneumovirus (HMPV), rhinovirus types A and B, human coronaviruses (HCoV) OC43, 229E/NL63] were investigated with those tests. In the study, 53.6% (375/700) of the patients were found to be infected with at least one virus and multiple respiratory virus infections were detected in 15.7% (59/375) of the positive cases, which were mostly (49/59, 83%) in pediatric patients. RSV and rhinovirus coinfections were the most prevalent (18/29, 62.7%) dual infections. The distribution of 436 respiratory viruses identified from 375 patients were as follows; 189 (43.3%) RSV, 93 (21.4%) rhinovirus, 86 (19.8%) INF-A, seven (1.6%) INF-B, 22 (5%) PIV types 1-3, 14 (3.2%) HMPV, 11 (2.5%) HCoV, nine (2%) HBoV, and five (1.2%) adenovirus. Fifty-five (64%) out of 86 INF-A viruses were subtyped as hH3, 24 (27.9%) were sHI and seven (8.1%) were hHI. Avian H5 was not detected in any samples. The overall prevalence rates of INF-A, INF-B, RSV and other respiratory viruses were 12%, 1 %, 27%, and 14.6%, respectively. RSV was the most prevalent respiratory agent in pediatric (161/313, 51 %) cases, while INF-A virus in adult (24/62, 38.7%) patients. Influenza viruses were detected as responsible pathogens in 13.3% (93/700) of the patients with flu-like symptoms. Among the cases, a 1-month-old baby was infected with three virus strains (INF-A hHI+INF-A sHI +HCoV OC43) and a 82-year-old patient was infected with two INF-A virus subtypes (hH3 + sH1). INF-A viruses were mostly detected (79/86) in winter period, from December to March. INF-A virus sH1, was the most prevalent subtype in flu cases till February 2011 (22/86), after replaced by INF-A virus hH3. Beginning from February 2012, a significant increase observed in the cases infected with INF-A virus subtype hH3 (39/86). In conclusion, the identification and surveillance of influenza virus types and subtypes circulating in populations have importance both for epidemiological data and selection of vaccine strains.
- Published
- 2014
7. PENGARUH KOMPENSASI, GAYA KEPEMIMPINAN TRANSFORMASIONAL DAN LINGKUNGAN KERJA FISIK TERHADAP KEPUASAN KERJA PEGAWAI
- Author
-
Cok Gede Nata Wasistha and Agoes Ganesha Rahyuda
- Subjects
Business ,HF5001-6182 ,Finance ,HG1-9999 - Abstract
Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh kompensasi, gaya kepemimpinan transformasional, dan lingkungan kerja fisik terhadap kepuasan kerja pegawai, dimana penelitian ini dilakukan pada Dinas Pariwisata Kabupaten Gianyar. Penelitian ini menggunakan teori dasar two factor theory dan teknik analisis data yang digunakan dalam penelitian ini adalah regresi linier berganda. Jumlah sampel yang di ambil dalam penelitian ini sebanyak 45 responden yang berstatus sebagai pegawai negeri sipil (PNS), dengan menggunakan metode sampel jenuh. Pengumpulan data dilakukan dengan cara wawancara dan penyebaran kuesioner. Berdasarkan hasil analisis penelitian, ditemukan bahwa kompensasi, gaya kepemimpinan transformasional, dan lingkungan kerja fisik berpengaruh positif terhadap kepuasan kerja pegawai. Jika seorang pemimpin memberikan perhatian terhadap bawahan, organisasi memberikan kompensasi yang sesuai dan adil, dan lingkungan kerja fisik yang nyaman dan kondusif, maka itu semua akan mampu meningkatkan kepuasan kerja pegawai. Kata kunci: kompensasi, kepemimpinan, lingkungan, kepuasan kerja
- Published
- 2018
- Full Text
- View/download PDF
8. Ashta Bhumi, Panduan Pembuatan Lay Out Ruang Bangunan Hunian Rumah Tinggal Tradisional Bali Madya
- Author
-
Anak Agung Gede Rai Remawa and Cok Gde Rai Padmanaba
- Subjects
Ashta Bhumi, Pah Pinara Sanga, Depa,Hasta dan Tapak ,Arts in general ,NX1-820 - Abstract
Ashta Bhumi adalah pengetahuan yang membahas tentang konsep ruang yang bersumber dari lontar, khususnya yang berhubungan dengan perancangan lay out ruang pekarangan di dalam bangunan hunian rumah tinggal tradisional Bali Madya. Sistem pengukuran jaraknya menggunakan satuan depa dan tapak yang diambil dari ukuran tubuh, tangan dan telapak kaki kepala keluarga laki-laki. Dasar pengukuran pekarangan huniannya menggunakan satuan depa-hasta-musti atau kelipatannya yang terdiri dari; ukuran Gajah (15x14), Dwaja (14x13), Singa (13x12) dan Wreksa (12x11). Beragamnya jenis ukuran yang terdapat pada hunian Bali Madya, adalah masalah yang sangat kompleks, maka dari itu penelitian ini akan mengamati dan meneliti jenis ukuran Gajah (sukat Gajah), Dwaja (sukat Dwaja), Singa (sukat Singa) dan Wreksa (sukat Wreksa). Ukuran ini banyak diterapkan oleh masyarakat tradisional Bali, karena digunakan oleh kalangan masyarakat luas. Setelah pengukuran tahap pertama ini, kemudian dilanjutkan dengan pengukuran berikutnya yaitu Sukat Pah Pinara Sanga, Sukat Tampak, Sukat Tampak Ngandang, dan Sukat Tampak Guli, untuk menentukan keluasan dan pembagian areal pekarangannya serta jarak antara bangunannya. Penelitian ini menggunakan metode deskriptif analitik dan bersifat kualitatif dengan pendekatan etnosains (etnografi), untuk mengetahui bagaimana masyarakat mengorganisir budayanya, sebagai sebuah konsep ruang masa lalu. Hasil dan manfaat dari penelitian ini adalah untuk mengetahui dasar pembentukan lay out ruang pekarangan dalam bangunan hunian rumah tinggal tradisional Bali Madya.
- Published
- 2021
- Full Text
- View/download PDF
9. Pulmonary function parameters in patients with diabetes mellitus
- Author
-
Özmen, Bilgin, primary, Çelik, P, additional, Yorgancioğlu, A, additional, Özmen, B, additional, Özmen, D, additional, and Çok, G, additional
- Published
- 2002
- Full Text
- View/download PDF
10. Organochlorine Pesticide Residue Levels in Human Adipose Tissue of Residents of Manisa (Turkey), 19951996
- Author
-
Çok, G ., primary, Bilgili, A., additional, Yarsan, E., additional, ci, C. Bag , additional, and Burgaz, S., additional
- Published
- 1998
- Full Text
- View/download PDF
11. Analysis Grounding System as Building Equipment Security Udayana University Denpasar
- Author
-
I G. N. Janardana, W. Arta Wijaya, Cok Gede Indra Partha, and N. Budiastra
- Subjects
Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Grounding system is one of the components in building equipment security. To fulfill the operational continuity of electronic equipment in Faculty of Engineering, Udayana University, Denpasar, a grounding system with a ground resistance of ? 3 ohms is required to be installed. The aim of this study is to find out the characteristics of grounding system to secure the equipment in the building around the research location, with ground resistance of ? 3 ohms and it is expected to be beneficial to use as a reference in grounding system installation as well as. According to the measurement results at the research location, it is found that the soil resistance value is equal to 0.23 ohms, where the soil resistivity (?) is 28.89 Ohm-meters. There are some results analysis obtained in ground resistance value of ? 3 Ohm. Those are 1) grounding system type 1 rod where minimal depth installation of the electrode is 14 meters with ground resistance value of 2.6751 ohms; 2) grounding system type two rod with s < L, it is obtained that each depth is 8 meters with distance of 2 meters between electrodes, where the ground resistance value is 2.4940 ohms. In the installation of two electrodes with s > L, it is gained that the depth of each electrode is 6 meters where the distance between the electrodes is 8 meters and the ground resistance value is 2.8718 ohms. By applying the plates type grounding system with 3 meters in length, 1 meter in width, and 2 meters in installation depth is gained 2.8431 ohms ground resistance value. Furthermore, by applying grid type grounding system with 2 meters in length h = 2,5 meters in depth, A = 4 meters in width and the total length of the electrode diameter 1 cm is 504 meters, it is obtained 2.0978 ohms ground resistance value.
- Published
- 2017
- Full Text
- View/download PDF
12. Rancang Bangun Sistem Monitoring Arus Beban pada Gardu Distribusi Menggunakan Short Message Service
- Author
-
Ignatius I Wayan Rexci Indra Parmana, Cok Gede Indra partha, and Ngakan Putu Satriya Utama
- Subjects
SMS, Gardu Distribusi, Monitoring, PLN ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Gardu distribusi merupakan komponen utama dari sistem distribusi tenaga listrik. PLN sebagai penyedia kebutuhan listrik di Indonesia masih menggunakan cara konvensional dalam memonitor arus beban pada gardu distribusi dengan datang ke lokasi dan mengambil data. Rancang bangun sistem monitoring arus beban pada gardu distribusi menggunakan SMS merupakan perangkat yang diintegerasikan pada gardu distribusi. Nilai arus beban yang dibaca dan dikonversi oleh sensor, informasi waktu dan tanggal secara real time ditampilkan pada LCD. Pengimplementasian sistem monitoring arus beban dilakukan pada gardu distribusi KA-0298 yang menyuplai Laboratorium Teknik Elektro Universitas Udayana. Perangkat ini dapat melakukan monitoring arus beban berdasarkan perintah yang dikirimkan melalui SMS. Perintah SMS yang dikirim dengan kode “CEKARUS” dapat diterima dan direspon oleh sistem monitoring arus beban dengan hasil balasan SMS informasi nilai arus beban fasa R, fasa S, fasa T dan fasa N pada gardu distribusi. Sistem data logger pada perangkat dapat digunakan untuk merekam perubahan arus beban pada gardu distribusi. Sistem notifikasi arus beban memberikan SMS peringatan jika terjadi gangguan arus beban pada gardu distribusi. [Turnitin Chek 7% 24032017]
- Published
- 2017
- Full Text
- View/download PDF
13. Improving Performance Stability of Power System Java-Bali Interconnection with PIDPSS3B and PIDSVC Controllers
- Author
-
Ida Bagus Gede Manuaba, Putu Arya Mertasana, Made Mataram, and Cok Gede Indra Partha
- Subjects
Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Modern electric power system that many its dynamic equipment continuously vulnerable to internal and external disturbances. On the condition of the disorder, it often happen oscillation in each part or between parts of the electrical system is interconnected. These oscillations become a major problem for the stability of the power system. Modern electrical control systems require a sustainable balance between power generation and demand varying loads. Power System Stabilizer and Static Var Compensator is a control device that is used to dampen low frequency oscillations and to provide additional feedback signal to stabilize the system. To increase the damping, system equipped with PSS generator that provides additional feedback to stabilize the signal in the excitation system. It is generally that the machine parameters changed by the load, so the dynamic behavior of the different machines at different operating conditions. Design PIDPSS3B power system stabilizer and PIDSVC controller used aim to get performance and optimum damping. Design and optimization of the proposed has the ability to optimally dampen and suppress errors are minimal.
- Published
- 2017
- Full Text
- View/download PDF
14. STUDI PENGARUH SETTING RELE PENGAMAN UNTUK MEMINIMALKAN GANGGUAN SYMPATHETIC TRIP PADA PENYULANG BUNISARI-SUWUNG
- Author
-
I Komang Anom Astana Ady, I Gede Dyana Arjana, and Cok Gede Indra Parta
- Subjects
Sistem proteksi, setting ground fault relay, Simpatitik Trip. ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Sympathetic Trip that happened in the electricity distribution system cause the healthy feeder distrupted because feel a disorder in feeder which affected by a disorder.A residual current that flows as a result of disruption of the one phase to ground on the Bunisari feeder as much as 183,9 A will be perceived by the same phase in the Suwung feeder which has a residual current of 196,9 A, that resulting in the accumulation of capacitive current as much as 380,8 A.The efforts obtained to prevent the Sympathetic trip back with ground fault relay setting as Iset = 25,72 A, tms = 0,11 SI with relay working time for 0,27 seconds and for Suwung feeder is obtained Iset = 24,59 A, tms = 0,115 SI with relay working time for 0,286 seconds.
- Published
- 2016
15. 10 Docetaxel concomitant with radiotherapy in patients with nonsmall cell lung cancer unresponsive to platinum-based induction chemotherapy
- Author
-
Ozkok, S., Yalman, D., Goker, E., Parvizi, M., Cok, G., Goksel, T., and Haydaroglu, A.
- Published
- 2005
- Full Text
- View/download PDF
16. Starting Points for Planning Business Zones in Slovenia in the Post-independence Period
- Author
-
Čok Gregor
- Subjects
Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
In Slovenia, during the period of transition practically all mechanisms for steering economic and spatial development changed. The planning of business zones is part of this framework; business zones are competitive business environments for the placement of economic activities in the physical space. Over the past 25 years, their design was influenced by various factors: introduction of free market principles, privatisation of social property, and interests of the young state to establish, using proper strategies and financial initiatives, an efficient network of zones as drivers of economic development. Despite the ambitious plans and adopted strategic spatial planning acts at the national level we nowadays find that the zones, in their current spatial and administrative form, are not an efficient enough development mechanism. The focus of the study was to define the starting points as the basis for planning business zones and shaping policies to improve the existing situation. To improve the business competitiveness of the existing zones and their role in the planning and design system, we will have to set up a more efficient data updating system and form a broader approach to their management, promotion, and marketing.
- Published
- 2016
- Full Text
- View/download PDF
17. Calcific pulmonary nodule, is it wandering?
- Author
-
Akçam Tİ, Yavuz H, Çok G, and Savaş R
- Abstract
Wandering pulmonary nodule is defined as a nodule with morphologically identical features found in different regions of the lung on different imaging studies. In this article, we report a 61-year-old patient who was examined for cough and found to have an 8 mm calcific nodule in the lower lobe of the left lung on computed tomography (CT) scan (Fig. 1A, B). On follow-up CT scan two years later, a nodule with the same morphology and size was detected in the same lobe but at a different location (Fig. 1C, D)., Competing Interests: Conflict of interestThe authors declare no conflict of interest., (© Indian Association of Cardiovascular-Thoracic Surgeons 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
- Published
- 2024
- Full Text
- View/download PDF
18. The Contribution of Fluorine 18 F-FDG PET/CT to Lung Cancer Diagnosis, Staging and Treatment Planning.
- Author
-
Budak E, Çok G, and Akgün A
- Abstract
Objective: Lung cancer is the most common cause of cancer-related death throughout the world, and the correct choice of treatment based on early diagnosis and staging increases the chance of survival. The present study aims to investigate the contribution of fluorine 18-fluorodeoxyglucose-positron emission tomography/computed tomography (
18 F-FDG PET/CT) to the management of lung cancer., Methods: In this study, 50 patients who underwent18 F-FDG PET/CT for lung cancer diagnosis and staging between February 2012 and February 2014 were included. The maximum standardized uptake value (SUVmax ) of the primary lung lesion along with other findings of18 F-FDG PET/CT and the results of histopathologic and conventional examinations were evaluated retrospectively. The mean survival time of patients was determined, and the findings were compared by using statistical methods., Results: Histopathologic examinations revealed 51 lung cancers in 50 patients. The sensitivity, accuracy and positive predictive value of18 F-FDG PET/CT in detecting primary malignancy were 94%, 94%, 100%, respectively. Adenocarcinoma (n=23, 16.8±13.5) and squamous cell carcinoma (n=15, 17.9±5.6) did not differ significantly regarding their mean SUVmax values (p=0.2). A statistically significant positive correlation (r=0.4) was identified between tumor size and SUVmax value for 51 tumors (p=0.002). The18 F-FDG PET/CT result was true negative in nine, false positive in six, true positive in two, and false negative in four patients who underwent histopathologic evaluation of their lymph nodes. The18 F-FDG PET/CT changed treatment planning in 34% of the patients. No significant relationship was identified between SUVmax value of the tumor and patient survival in patients (p=0.118)., Conclusion: The present study concluded that PET/CT was an efficient method in the diagnosis and staging of lung cancer since it provided useful information in addition to conventional methods. It was also observed that PET/CT scanning resulted in a change in therapeutic plans in the majority of patients. However, there was no statistically significant relationship between survival and the SUVmax of the primary mass.- Published
- 2018
- Full Text
- View/download PDF
19. The role of apelin in the assessment of response to chemotherapyand prognosis in stage 4 nonsmall cell lung cancer.
- Author
-
Ermin S, Çok G, Veral A, and Köse T
- Subjects
- Aged, Apelin, Disease-Free Survival, Female, Humans, Male, Middle Aged, Neoplasm Staging, Prognosis, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms
- Abstract
Background/aim: Prediction of response to chemotherapy and prognosis bears clinical significance in patients with lung cancer. The aim of the study was to examine the association between apelin expression in tumor tissues and overall survival, progression-free survival, chemoresistance, and treatment response in stage 4 nonsmall cell lung cancer (NSCLC) patients undergoing chemotherapy., Materials and Methods: A total of 81 patients who received chemotherapy due to a biopsy-documented diagnosis of NSCLC between 2004 and 2011 were retrospectively studied. Bronchoscopic biopsy samples were examined immunohistochemically., Results: Of the overall study population (n = 81), the mean age was 59.0 ± 9.2 years; 83% (n = 67) were male and 17% (n = 14) were female. All patients received chemotherapy. A total of 30 patients (37%) had no apelin positivity, while 21 (30%) had 1 +, 20 (25%) had 2 +, and 10 (12%) had 3 + apelin positivity. We detected no association between apelin positivity and overall survival, 6-month survival, or 1-year survival rates (P = 0.05, 0.74, and 0.63). Patients with apelin expression as compared to those without it had shorter overall survival (P = 0.05)., Conclusion: Our results suggest that apelin, an angiogenic factor, does not seem to provide significant prognostic information in this patient group.
- Published
- 2016
- Full Text
- View/download PDF
20. [Prevalence and seasonal distribution of respiratory viruses in patients with acute respiratory tract infections, 2002-2014].
- Author
-
Çiçek C, Arslan A, Karakuş HS, Yalaz M, Saz EU, Pullukçu H, and Çok G
- Subjects
- Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Cell Line, Child, Child, Preschool, Female, Fluorescent Antibody Technique, Direct, Humans, Infant, Infant, Newborn, Inpatients, Male, Middle Aged, Outpatients, Polymerase Chain Reaction methods, Prevalence, Respiratory Tract Infections virology, Seasons, Sex Distribution, Turkey epidemiology, Virus Diseases virology, Young Adult, Respiratory Tract Infections epidemiology, Virus Diseases epidemiology
- Abstract
The aim of this study was to investigate the prevalence and seasonal distribution of respiratory viruses in pediatric and adult outpatients and inpatients who were admitted to hospital with the symptoms of upper and lower respiratory tract infections, during a 12-year period. A total of 5102 clinical samples (4372 nasopharyngeal swabs, 316 bronchoalveolar lavages, 219 transtracheal aspirates, 163 nasopharyngeal aspirates, 20 sputum, 10 nasal swabs) examined in our laboratory between January 1st 2002 and July 17th 2014, were evaluated retrospectively. Of the specimens, 1107 (21.7%) were obtained from outpatients and 3995 (78.3%) from hospitalized patients. Of the patients, 2851 (55.9%) were male and 2251 (44.1%) were female, while 1233 (24.2%) were adults and 3869 (75.8%) were children (age range: 1 day - 93 years; median: 3 years). Respiratory samples were investigated for the presence of respiratory syncytial virus (RSV), influenza virus type A and B (INF-A, INF-B), adenovirus (AdV), parainfluenza viruses (PIV types 1-4), human rhinoviruses (HRV), human coronaviruses (HCoV), human metapneumovirus (HMPV) and human bocavirus (HBoV). All specimens were tested by both direct immunofluorescence antibody (DFA) and shell vial cell culture (SVCC) methods. In DFA assay the samples were initially screened by fluorescent-labeled polyclonal antibodies, and the positive ones were typed by using monoclonal antibodies (Light Diagnostics, Merck Millipore, USA). In SVCC, HEp-2, MDCK, A-549 and Vero cell lines were used for the isolation of viruses. In addition to these methods, real-time multiplex PCR methods (RealAccurate®, Respiratory RT PCR, PathoFinder, Netherlands and Seeplex® RV15 ACE Detection, Seegene, South Korea) were used for the detection of respiratory viruses in samples (n= 2104) obtained from 2007 to 2014. Respiratory viruses were detected in a total of 1705 (33.4%) patients, of them 967 (19%) were male and 738 (14.4%) were female. Three hundred and eighteen (18.6%) of the 1705 patients were infected with multiple respiratory viruses. The most frequently observed co-infections were RSV+INF-A (40/318; 12.6%), and RSV+PIV (33/318; 10.4%). The rate of positivity for the respiratory viruses in pediatric and adult groups were 35.4% (1369/3869) and 27.3% (336/1233), respectively (p< 0.000). The most frequently detected virus in pediatric group was RSV (336/1369; 24.5%), followed by influenza viruses (314/1369; 22.9%), PIV (197/1369; 14.4%), HRV (118/1369; 8.6%), AdV (75/1369; 5.5%) and the others (49/1369; 3.6%). On the other hand the most frequently detected virus in adult group was influenza viruses (181/336; 53.8%) followed by AdV (37/336; 11%), RSV (24/336; 7.1%), PIV (24/336; 7.1%), HRV (23/336; 6.8%) and the others (9/336; 2.7%). The rate of multiple virus infections in pediatric and adult groups were 7.2% (280/3869) and 3% (38/1233), respectively. Most of the coinfections (280/318; 88%) were detected in children. Respiratory viruses were detected positive in 40.2% (445/1107) of outpatients, and in 31.5% (1260/3995) of inpatients (p< 0.000). The most frequent viruses detected in pediatric outpatients and inpatients were HRV and RSV, respectively, while influenza viruses were the first in line among both adult outpatients and inpatients. During the study period, a PIV-3 outbreak (n= 96) have emerged between December 2004-April 2005, and an influenza A (H1N1)pdm09 outbreak (n= 207) between November 2009-January 2010. When the seasonal distribution was considered, the isolation rates of 1705 respiratory viruses in winter, spring, summer and autumn were 44.4%, 27%, 8.3% and 20.3%, respectively. RSV was most frequently detected from December to March, influenza viruses from November to March, HRV from December to June, and mixed infections from January to February. In conclusion, the data of our study obtained in about 12-year period indicated that the prevalence of respiratory viruses in acute respiratory infections is 33.4%, and they typically active during the months of winter and early spring in our region.
- Published
- 2015
- Full Text
- View/download PDF
21. Expression of p63, TTF-1 and Maspin in Non-Small Cell Lung Carcinoma and Their Effect on the Prognosis and Differential Diagnosis.
- Author
-
Yaman B, Nart D, Ekren PK, Çok G, and Veral A
- Subjects
- Adult, Aged, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung mortality, Carcinoma, Non-Small-Cell Lung pathology, Carcinoma, Non-Small-Cell Lung surgery, Diagnosis, Differential, Disease-Free Survival, Female, Humans, Immunohistochemistry, Kaplan-Meier Estimate, Lung Neoplasms mortality, Lung Neoplasms pathology, Male, Middle Aged, Neoplasm Staging, Pneumonectomy, Predictive Value of Tests, Proportional Hazards Models, Retrospective Studies, Risk Factors, Thyroid Nuclear Factor 1, Treatment Outcome, Tumor Burden, Biomarkers, Tumor analysis, Carcinoma, Non-Small-Cell Lung chemistry, Lung Neoplasms chemistry, Lung Neoplasms surgery, Nuclear Proteins analysis, Serpins analysis, Transcription Factors analysis, Tumor Suppressor Proteins analysis
- Abstract
Objective: Lung cancer is still the leading cause of cancer mortality. Antiapoptotic genes and protease inhibitors play an important role in the development of lung cancer., Material and Method: p63, TTF-1 and maspin expression and their role in the differential diagnosis, overall survival, progression-free survival and other clinicopathological characteristics of the patients were investigated in 80 surgically-resected non-small cell lung carcinomas., Results: The maximal tumor diameter range was 1.5-11 cm (mean: 4.06±1.8 cm). Forty-five (56.3%) tumors were adenocarcinoma, 23 (28.8%) squamous cell carcinoma, four (5%) large cell carcinoma, six (7.5%) large cell neuroendocrine carcinoma, one (1.2%) sarcomatoid carcinoma while one was (1.2%) both adenocarcinoma and squamous cell carcinoma. The patients with advanced TNM stage and a tumor diameter more than 3 cm had markedly poor survival. Immunohistochemically, p63 staining was present in 87.5% of squamous cell carcinomas, 4.3% of adenocarcinomas, 25% of large cell carcinomas, and 16.7% of large cell neuroendocrine carcinomas. Similarly, maspin was positive in 66.7% of squamous cell carcinomas and 17.4% of adenocarcinomas. The TTF-1 staining rate was higher in adenocarcinomas (84.8%). There was no immunoreactivity in squamous cell carcinomas (p < 0.001). We found that p63 and TTF-1 had no significant effect on survival in either tumor group (p > 0.05) while maspin has a negative prognostic effect in adenocarcinoma (p=0.048)., Conclusion: This study suggests that p63 and TTF-1 are reliable markers in non-small cell lung carcinoma and can be used in differential diagnosis. Maspin has been identified as a prognostic marker in adenocarcinoma. However, more studies are required to elucidate the significance of maspin.
- Published
- 2015
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.