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2. Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?

Author

Celegen, Kubra, Gulhan, Bora, Fidan, Kibriya, Yuksel, Selcuk, Yilmaz, Neslihan, Yılmaz, Aysun Caltik, Demircioğlu Kılıç, Beltinge, Gokce, Ibrahim, Kavaz Tufan, Aslı, Kalyoncu, Mukaddes, Nalcacıoglu, Hulya, Ozlu, Sare Gulfem, Kurt Sukur, Eda Didem, Canpolat, Nur, K. Bayazit, Aysun, Çomak, Elif, Tabel, Yılmaz, Tulpar, Sebahat, Celakil, Mehtap, Bek, Kenan, Zeybek, Cengiz, Duzova, Ali, Özçakar, Zeynep Birsin, Topaloglu, Rezan, Soylemezoglu, Oguz, and Ozaltin, Fatih

Published
2024
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4. Complement gene mutations in children with C3 glomerulopathy: do they affect the response to mycophenolate mofetil?

Author

Günay, Neslihan, Dursun, İsmail, Gökçe, İbrahim, Akbalık Kara, Mehtap, Tekcan, Demet, Çiçek, Neslihan, Torun Bayram, Meral, Koyun, Mustafa, Dinçel, Nida, Dursun, Hasan, Saygılı, Seha, Yürük Yıldırım, Zeynep Nagehan, Yüksel, Selçuk, Dönmez, Osman, Yel, Sibel, Demircioğlu Kılıç, Beltinge, Aydoğ, Özlem, Atmış, Bahriye, Çaltık Yılmaz, Aysun, Bakkaloğlu, Sevcan A., Aytaç, Mehmet Baha, Taşdemir, Mehmet, Kasap Demir, Belde, Soylu, Alper, Çomak, Elif, Kantar Özşahin, Aslı, Kaçar, Alper, Canpolat, Nur, Yılmaz, Alev, Girişgen, İlknur, Akkoyunlu, Kadirye Betül, Alpay, Harika, and Poyrazoğlu, Hakan M.

Published
2024
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5. Characteristics and predictors of chronic kidney disease in children with myelomeningocele: a nationwide cohort study

Author

Doğan, Çağla Serpil, Taner, Sevgin, Tiryaki, Betül Durucu, Alaygut, Demet, Özkayın, Neşe, Kara, Aslıhan, Gençler, Aylin, Pınarbaşı, Ayşe Seda, Nalçacıoğlu, Hülya, Yüksel, Selçuk, Akacı, Okan, Yılmaz, Esra Karabağ, Yavuz, Sevgi, Doğan, Kenan, Gülşan, Rumeysa Yasemin Çiçek, Aksoy, Gülşah Kaya, Çiçek, Neslihan, Aksu, Bağdagül, Küçük, Nuran, Altugan, Fatma Şemsa, Selçuk, Şenay Zırhlı, Baştuğ, Funda, Erfidan, Gökçen, Atmış, Bahriye, Gökçeoğlu, Arife Uslu, Önder, Esra Nagehan Akyol, Elmacı, Ahmet Mithat, Cengiz, Nurcan, Gülleroğlu, Kaan, Yılmaz, Ebru Bekiroğlu, Tayfur, Aslı Çelebi, Yılmaz, Gülsün Gülay, Yel, Sİbel, Pehlivanoğlu, Cemile, Akgün, Cihangir, Kara, Mehtap Akbalık, Kılıç, Beltinge Demircioğlu, Şimşek, Özgür Özdemir, Yucal, Melike, Ağar, Buket Esen, Gürgöze, Metin Kaya, Yağmur, İsmail, Madsar, Ömer, Karalı, Demet Tekcan, Girişgen, İlknur, Bodur, Ece Demirci, Çomak, Elif, Gökçe, İbrahim, Kaya, Mehtap, Tabel, Yılmaz, Günay, Neslihan, Gülmez, Rüveyda, and Çalışkan, Salim

Published
2024
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6. Correction to: Adolescence‑onset atypical hemolytic uremic syndrome: is it different from infant‑onset?

Author

Celegen, Kubra, Gulhan, Bora, Fidan, Kibriya, Yuksel, Selcuk, Yilmaz, Neslihan, Yılmaz, Aysun Caltik, Demircioğlu Kılıç, Beltinge, Gokce, Ibrahim, Kavaz Tufan, Aslı, Kalyoncu, Mukaddes, Nalcacıoglu, Hulya, Ozlu, Sare Gulfem, Kurt Sukur, Eda Didem, Canpolat, Nur, K. Bayazit, Aysun, Çomak, Elif, Tabel, Yılmaz, Tulpar, Sebahat, Celakil, Mehtap, Bek, Kenan, Zeybek, Cengiz, Duzova, Ali, Özçakar, Zeynep Birsin, Topaloglu, Rezan, Soylemezoglu, Oguz, and Ozaltin, Fatih

Published
2024
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11. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study

Author

Kısaarslan, Ayşenur Paç, Çiçek, Sümeyra Özdemir, Batu, Ezgi D., Şahin, Sezgin, Gürgöze, Metin K., Çetinkaya, Sibel Balcı, Ekinci, Miray Kışla, Atmış, Bahriye, Barut, Kenan, Adrovic, Amra, Ağar, Buket Esen, Şahin, Nihal, Demir, Ferhat, Bağlan, Esra, Kara, Mehtap Akbalık, Selçuk, Şenay Zırhlı, Özdel, Semanur, Çomak, Elif, Akkoyunlu, Betül, Yener, Gülçin Otar, Yıldırım, Deniz Gezgin, Öztürk, Kübra, Yıldız, Mehmet, Haşlak, Fatih, Şener, Seher, Kısaoğlu, Hakan, Baba, Özge, Kızıldağ, Zehra, İşgüder, Rana, Çağlayan, Şengül, Bilgin, Raziye B. Güven, Aytaç, Gülçin, Yücel, Burcu Bozkaya, Tanatar, Ayşe, Sönmez, Hafize E., Çakan, Mustafa, Kara, Aslıhan, Elmas, Ahmet T., Kılıç, Beltinge Demircioğlu, Ayaz, Nuray Aktay, Kasap, Belde, Acar, Banu Çelikel, Ozkaya, Ozan, Yüksel, Selçuk, Bakkaloğlu, Sevcan, Aydoğ, Özlem, Aksu, Güzide, Akman, Sema, Dönmez, Osman, Bülbül, Mehmet, Büyükçelik, Mithat, Tabel, Yılmaz, Sözeri, Betül, Kalyoncu, Mukaddes, Bilginer, Yelda, Poyrazoğlu, Muammer H., Ünsal, Erbil, Kasapçopur, Özgür, Özen, Seza, and Düşünsel, Ruhan

Published
2023
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13. Comparison of infants and children with urolithiasis: a large case series

Author

Baştuğ, Funda, Ağbaş, Ayşe, Tülpar, Sebahat, Yıldırım, Zeynep Nagehan Yürük, Çiçek, Neslihan, Günay, Neslihan, Gemici, Atilla, Çelik, Binnaz, Delebe, Emine Özlem Çam, Nalçacıoğlu, Hülya, Yılmaz, Alev, Gökçe, İbrahim, Demircin, Gülay, Hacıhamdioğlu, Duygu Övünç, Yılmaz, Kenan, Atmış, Bahriye, Yılmaz, Esra Karabağ, Ertan, Pelin, Dursun, İsmail, Aksu, Bağdagül, Akbulut, Burcu Bulum, Döven, Serra Sürmeli, Öner, Nimet, Yel, Sibel, Elmacı, Ahmet Midhat, Atikel, Yeşim Özdemir, Erfidan, Gökçen, Uysal, Berfin, Bıyıklı, Neşe, Yazıcıoğlu, Burcu, Küçük, Nuran, Çomak, Elif, Sever, Fatma Lale, Akil, İpek, Aksoy, Özlem, and Alpay, Harika

Published
2022
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18. Thrombotic Microangiopathy Associated with Macrophage Activation Syndrome: A Multinational Study of 23 Patients

Author

Minoia, Francesca, Tibaldi, Jessica, Muratore, Valentina, Gallizzi, Romina, Bracaglia, Claudia, Arduini, Alessia, Comak, Elif, Vougiouka, Olga, Trauzeddel, Ralf, Filocamo, Giovanni, Mastrangelo, Antonio, Micalizzi, Concetta, Kasapcopur, Ozgur, Unsal, Erbil, Kitoh, Toshiyuki, Tsitsami, Elena, Kostik, Mikhail, Schmid, Jana Pachlopnik, Prader, Seraina, Laube, Guido, Maritsi, Despoina, Jelusic, Marija, Shenoi, Susan, Vastert, Sebastiaan, Ardissino, Gianluigi, Cron, Randy Q., and Ravelli, Angelo

Published
2021
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19. Predictors of poor kidney outcome in children with C3 glomerulopathy

Author

Pinarbasi, Ayse Seda, Dursun, Ismail, Gokce, Ibrahim, Çomak, Elif, Saygili, Seha, Bayram, Meral Torun, Donmez, Osman, Melek, Engin, Tekcan, Demet, Cicek, Neslihan, Yilmaz, Dilek, Tabel, Yilmaz, Yildirim, Zeynep Y., Bahat, Elif, Koyun, Mustafa, Soylu, Alper, and Canpolat, Nur

Subjects
Chronic kidney failure -- Risk factors, Glomerulonephritis -- Prognosis -- Complications and side effects, Pediatric research, Health
Abstract

Background C3 glomerulopathy (C3G) is characterized by heterogeneous clinical presentation, outcome, and predominant C3 accumulation in glomeruli without significant IgG. There is scarce outcome data regarding childhood C3G. We describe clinical and pathological features, treatment and outcomes, and risk factors for progression to chronic kidney disease stage 5 (CKD5) in the largest pediatric series with biopsy-proven C3G. Methods Sixty pediatric patients with C3G from 21 referral centers in Turkey were included in this retrospective study. Patients were categorized according to CKD stage at last visit as CKD5 or non-CKD5. Demographic data, clinicopathologic findings, treatment, and outcome data were compared and possible risk factors for CKD5 progression determined using Cox proportional hazards model. Results Mean age at diagnosis was 10.6 ± 3.0 years and follow-up time 48.3 ± 36.3 months. Almost half the patients had gross hematuria and hypertension at diagnosis. Nephritic-nephrotic syndrome was the commonest presenting feature (41.6%) and 1/5 of patients presented with nephrotic syndrome. Membranoproliferative glomerulonephritis was the leading injury pattern, while 40 patients had only C3 staining. Patients with DDD had significantly lower baseline serum albumin compared with C3GN. Eighteen patients received eculizumab. Clinical remission was achieved in 68.3%. At last follow-up, 10 patients (16.6%) developed CKD5: they had lower baseline eGFR and albumin and higher frequency of nephrotic syndrome and dialysis requirement than non-CKD5 patients. Lower serum albumin and eGFR at diagnosis were independent predictors for CKD5 development. Conclusions Children with C3G who have impaired kidney function and hypoalbuminemia at diagnosis should be carefully monitored for risk of progression to CKD5. Graphical abstract, Author(s): Ayse Seda Pinarbasi [sup.1] , Ismail Dursun [sup.1] , Ibrahim Gokce [sup.2] , Elif Çomak [sup.3] , Seha Saygili [sup.4] , Meral Torun Bayram [sup.5] , Osman Donmez [sup.6] [...]

Published
2021
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20. Predictors of poor kidney outcome in children with C3 glomerulopathy

Author

Pınarbaşı, Ayşe Seda, Dursun, Ismail, Gokce, Ibrahim, Çomak, Elif, Saygılı, Seha, Bayram, Meral Torun, Donmez, Osman, Melek, Engin, Tekcan, Demet, Çiçek, Neslihan, Yılmaz, Dilek, Tabel, Yılmaz, Yıldırım, Zeynep Y., Bahat, Elif, Koyun, Mustafa, Soylu, Alper, Canpolat, Nur, Aksu, Bağdagül, Çelakıl, Mehtap Ezel, Taşdemir, Mehmet, Benzer, Meryem, Özçelik, Gül, Bakkaloğlu, Sevcan A., and Düşünsel, Ruhan

Published
2021
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21. Comparison of EULAR/PRINTO/PReS Ankara 2008 and 2022 ACR/EULAR classification criteria for granulomatosis with polyangiitis in children.

Author

Akca, Ummusen Kaya, Batu, Ezgi Deniz, Jelusic, Marija, Calatroni, Marta, Bakry, Reima, Frkovic, Marijan, Vinšová, Nikol, Campos, Reinan T, Horne, AnnaCarin, Caglayan, Sengul, Vaglio, Augusto, Moroni, Gabriella, Emmi, Giacomo, Ghiggeri, Gian Marco, Koker, Oya, Sinico, Renato Alberto, Kim, Susan, Gagro, Alenka, Matucci-Cerinic, Caterina, and Çomak, Elif

Subjects
PREDICTIVE tests, SCHOENLEIN-Henoch purpura, MICROSCOPIC polyangiitis, RETROSPECTIVE studies, BEHCET'S disease, COGAN syndrome, GRANULOMATOSIS with polyangiitis, PEDIATRICS, MEDICAL records, ACQUISITION of data, TAKAYASU arteritis, SENSITIVITY & specificity (Statistics), POLYARTERITIS nodosa, CHILDREN
Abstract

Objective Granulomatosis with polyangiitis (GPA) is an ANCA-associated vasculitis. The 2022 ACR/EULAR-endorsed classification criteria for GPA was derived using data only from adult patients. We aimed to assess the performance of the ACR/EULAR classification criteria for GPA in paediatric patients and compare it with the EULAR/Pediatric Rheumatology International Trials Organization (PRINTO)/Pediatric Rheumatology European Society (PReS)-endorsed Ankara 2008 criteria for GPA. Methods Retrospective data of paediatric patients with GPA in 20 centres from 9 countries were evaluated. The diagnosis of GPA was made according to the expert opinion. The sensitivity, specificity, positive predictive value, and negative predictive value of the criteria sets were evaluated. Results The study included 77 patients with GPA and 108 controls [IgA vasculitis (n  = 44), Takayasu's arteritis (n  = 20), microscopic polyangiitis (n  = 16), polyarteritis nodosa (n  = 14), Behçet's disease (n  = 12), eosinophilic granulomatosis with polyangiitis (n  = 1) and Cogan's syndrome (n  = 1)] with a median age of 17.8 and 15.2 years, respectively. Among patients with GPA, constitutional symptoms (85.7%) and ENT involvement (79.2%) were the most common presentations. In the GPA group, 73 patients fulfilled the Ankara 2008 criteria and 69 the ACR/EULAR classification criteria. Sensitivities of the Ankara 2008 criteria and the ACR/EULAR classification criteria were 94.8% and 89.6%, while specificities were 95.3% and 96.3%, respectively. No significant difference was found between sensitivities and specificities of both classification criteria (P  = 0.229 and P  = 0.733, respectively). Conclusion In children, both the ACR/EULAR and EULAR/PRINTO/PReS Ankara 2008 classification criteria for GPA perform well and similarly. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Orthostatic proteinuria: an overestimated phenomenon?

Author

Arslan, Zümrüt, Koyun, Mustafa, Erengin, Hakan, Akbas, Halide, Aksoy, Gülsah Kaya, Çomak, Elif, and Akman, Sema

Subjects
Proteinuria -- Diagnosis -- Demographic aspects, Students -- Health aspects -- Medical examination, Health
Abstract

Background Although orthostatic proteinuria (OP) is the most common cause of childhood proteinuria, excluding transient proteinuria, data regarding prevalence and long-term prognosis are limited. We aimed to determine prevalence of OP in healthy schoolchildren evaluating relationships with age, gender and body mass index, and determine follow-up. Methods A total of 1701 healthy children aged 6-15 years were selected using a population-based, stratified, cluster-sampling method; and random urine samples were taken. For proteinuria [greater than or equal to] 1+ in first urine samples, second and third random samples were taken at least 2 weeks apart to exclude transient proteinuria. For continuing proteinuria after third samples, first morning urine samples were collected. Cases where proteinuria was not detected in first morning urine samples were diagnosed as OP. Results Sixty-four of 1701 children (3.7%) had proteinuria on first random urine samples. After second and third urine samples, proteinuria persisted in only 16 (0.94%). OP was detected in 11 (0.65%). Prevalence of OP tended to decrease with increasing BMI, though not statistically significant. All 7 cases with OP who were re-evaluated later, had no proteinuria 3 years after diagnosis. Conclusions Prevalence of OP in our study was lower than the literature. At least three random urine samples should be taken to exclude transient proteinuria in an asymptomatic child/adolescent before making a diagnosis of OP using first morning urine samples. OP is a benign condition and resolves spontaneously in most cases. Underweight children had a tendency for OP compared with overweight and obese children; however, further studies with larger number of patients are needed., Author(s): Zümrüt Arslan [sup.1] , Mustafa Koyun [sup.2] , Hakan Erengin [sup.3] , Halide Akbas [sup.4] , Gülsah Kaya Aksoy [sup.2] , Elif Çomak [sup.2] , Sema Akman [sup.2] Author [...]

Published
2020
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27. Comprehensive evaluation of patients with primary hyperoxaluria type 1: A nationwide study

Author

Bakkaloğlu, Sevcan A., primary, Büyükkaragöz, Bahar, additional, Pınarbaşı, Ayşe Seda, additional, Leventoğlu, Emre, additional, Saygılı, Seha, additional, Çomak, Elif, additional, Yıldırım, Zeynep Y., additional, Akıncı, Nurver, additional, Dursun, İsmail, additional, Karabay Bayazıt, Aysun, additional, Kavaz Tufan, Aslı, additional, Akman, Sema, additional, Yılmaz, Alev, additional, Noyan, Aytül, additional, Ağbaş, Ayşe, additional, Serdaroğlu, Erkin, additional, Delibaş, Ali, additional, Elmacı, Ahmet Midhat, additional, Taşdemir, Mehmet, additional, Ezgü, Fatih S., additional, and Sever, Lale, additional

Published
2024
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28. COVID-19 Effect in Pediatric Rheumatology Patients.

Author

Limon, Tuğba, Aksoy, Gülşah Kaya, Akman, Sema, Koyun, Mustafa, Öngüt, Gözde, Mutlu, Derya, Çomak, Elif, Kara, Tuğçe Tural, and Özyurt, Özlem Koyuncu

Abstract

Copyright of Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi is the property of Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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29. Comparison of EULAR/PRINTO/PReS Ankara 2008 and 2022 ACR/EULAR Classification Criteria for Granulomatosis with Polyangiitis in Children

Author

Kaya Akca, Ummusen, primary, Batu, Ezgi Deniz, additional, Jelusic, Marija, additional, Calatroni, Marta, additional, Bakry, Reima, additional, Frkovic, Marijan, additional, Vinšová, Nikol, additional, Campos, Reinan T, additional, Horne, AnnaCarin, additional, Caglayan, Sengul, additional, Vaglio, Augusto, additional, Moroni, Gabriella, additional, Emmi, Giacomo, additional, Ghiggeri, Gian Marco, additional, Koker, Oya, additional, Sinico, Renato Alberto, additional, Kim, Susan, additional, Gagro, Alenka, additional, Matucci-Cerinic, Caterina, additional, Çomak, Elif, additional, Ekici Tekin, Zahide, additional, Arslanoglu Aydin, Elif, additional, Heshin-Bekenstein, Merav, additional, Acar, Banu Celikel, additional, Gattorno, Marco, additional, Akman, Sema, additional, Sozeri, Betul, additional, Palmblad, Karin, additional, Al-Mayouf, Sulaiman M, additional, Silva, Clovis Artur, additional, Doležalová, Pavla, additional, Merkel, Peter A, additional, and Ozen, Seza, additional

Published
2023
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32. Clinical and histopathological prognostic factors affecting the renal outcomes in childhood ANCA-associated vasculitis

Author

Özçelik, Gül, Sönmez, Hafize Emine, Şahin, Sezgin, Özağarı, Ayşim, Bayram, Meral Torun, Çiçek, Rümeysa Yasemin, Çakıcı, Evrim Kargın, Çomak, Elif, Barut, Kenan, Şahin, Nihal, Bakkaloğlu, Sevcan, Gökçe, İbrahim, Düzova, Ali, Bilginer, Yelda, Açarı, Ceyhun, Melek, Engin, Kılıç, Beltinge Demircioğlu, Özdel, Semanur, Adroviç, Amra, Kasapçopur, Özgür, Ünsal, Erbil, Alpay, Harika, Orhan, Diclehan, Topaloğlu, Rezan, Düşünsel, Ruhan, and Özen, Seza

Published
2019
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49. The Role of Biofeedback Treatment in Children with Lower Urinary Tract Dysfunction

Author

ISIYEL, Emel, ÇOMAK, Elif, and ER, İlkay

Subjects
General and Internal Medicine, Biyofeedback tedavisi,Standart tedavi,Alt üriner sistem disfonksiyonu, biofeedback treatment,Lower urinary tract dysfunction,standard urotherapy, Genel ve Dahili Tıp
Abstract

Amaç: Alt üriner sistem disfonksiyonu geniş spektrumlu bir tanıdır ve Uluslarararası Çocuk İşeme Topluluğuna göre aşırı aktif mesane, işemeyi erteleme, az aktif mesane, seyrek işeme, vajinal reflü, mesane boynu disfonksiyonu ve kıkırdama inkontinansını içerir.Biyofeedback kolay uygulanabilen, girişimsel olmayan ve normal mesane ve barsak fonksiyonlarının sağlanmasında pelvik duvar kaslarını aktive etmek için kullanılan bir tedavi yöntemidir. Bu çalışmada alt üriner sistem disfonksiyonu olan çocuklarda biyofeedback tedavisinin etkinliğinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya alt üriner sistem disfonksiyonu tanısı alan ve standart tedaviye yanıt vermeyen 29 hasta dahil edildi. Bu hastalara 8 hafta süre ile biyofeedback tedavisi uygulandı. Bulgular: Animasyon biofeedback tedavisinden sonra 13 hastada (%44.8) gündüz, iki (%6.8) hastada gece kaçırma şikayetleri düzeldi. Kabızlığı olan 5 hastada tamamen düzelme olmasına rağmen enkoprezisi olan hastalarda düzelme olmadı. Altı hastanın (% 20.7) şikayetlerinde azalma oldu ancak tam düzelme olmadı. Biofeedback tedavisi öncesi 16.19±7.69 olan ortalama işeme bozuklukları semptom skoru, tedavi sonrası 9.52±6.4’e geriledi ve istatistiksel olarak anlamlı bir fark (p, Objective: Lower urinary tract dysfunction is a wide clinical spectrum and according to the International Children’s Continence Society, lower urinary tract dysfunction contains overactive bladder, voiding postponement, underactive bladder, infrequent voiding, extraordinary daytime only urinary frequency, vaginal reflux, bladder neck dysfunction, and giggle incontinence. Biofeedback is a non-invasive therapy that can be applied easily and aims to activate relevant pelvic wall muscles for normal bowel and bladder functions. This study aimed to evaluate the efficacy of biofeedback treatment in children with lower urinary tract dysfunction.Material and Methods: Twenty-nine patients who were diagnosed with lower urinary tract dysfunction and did not respond to standard therapy were included in the study. Biofeedback therapy was applied to these patients for 8 weeks. Results: After animation biofeedback treatment, daytime symptoms improved in 13 patients (44.8%), and nighttime enuresis improved in two (6.8%) patients. Although 5 patients with constipation completely improved, there was no improvement in patients with encopresis. There was a decrease but not a complete improvement in complaints of six patients (20.7%). Mean urinary incontinence symptom score which was 16.19±7.69 before biofeedback treatment decreased to 9.52±6.4 after the treatment, with a statistically significant difference (p

Published
2021

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