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Fabry disease (FD) is an X-linked, lysosomal glycosphingolipid storage disorder that occurs very rarely. Cardiac involvement may comprise of left ventricular hypertrophy (LVH), arrhythmias, conduction abnormalities, heart failure and valvular abnormalities. The goal of this study was to conduct gene analysis for FD in patients suffering from unexplained LVH. 120 patients over the age of 30 who were diagnosed by echocardiography with idiopathic LVH were included in the study. Patients with severe hypertension, intermediate valve disease such as moderate aortic stenosis, known FD, and a family history of autosomal dominant hypertrophic cardiomyopathy were excluded from the study. GLA gene mutations were studied by Sanger sequence analysis in all patients. Of the 120 total patients included in this study, 69 were female (58%) and 51 were male (42%). The mean age was 60.3 ± 15.7. GLA gene mutations were detected in three male patients. The detected mutations are as follows: NM_000169.2:IVS6-10G>A (c.1000–10G>A), NM_000169.2:c.937G>T (p.D313Y) (p.Asp313Tyr) and NM_000169.2:c.941A>T (p.K314M) (p.Lys314Met). Early diagnosis is of vital importance in FD, which can be treated with enzyme replacement. Genetic screening in patients diagnosed with idiopathic LVH by echocardiography is important in the early diagnosis and treatment of FD. Patients over 30 years of age with idiopathic LVH should be screened for FD. Various new polymorphisms can be detected in genetic screening. Identifying new polymorphisms is important for knowing the true mutations in FD.

Energy is an indispensable and ever- growing need in our daily lives. Due to the finite nature of our planet’s resources, the importance of renewable energy sources is increasing in tandem. For example, wind power plants (WPPs) are growingrapidly in use. In this studywehave calculated the relative efficiencies of 22 Turkish WPPs. As these WPPs are of different sizes, an initial cluster analysis was performed using data collected in the 2014-2016 period. For each cluster, data envelopment analysis (DEA) was conducted to calculate the relative efficiencies of the WPPs. DEA-derived weightings were then used to rank WPPs by TOPSIS (Technique for Order Preference by Similarity to Ideal Solution). Finally, DEA and TOPSIS rankings were compared.

In this paper, we obtain some new inequalities for functions whose second derivatives’ absolute value is s−convex and log −convex. Also, we give some applications for numerical integration.

In this paper, we establish Hermite-Hadamard type inequalities for (α, m)-convex functions via fractional integrals.

In every society, the issue of whether an individual can do math has become a central issue. Middle school years, when students' perceptions towards math start to form, have a critical importance for them to develop a positive attitude towards math. The aim of this study is to determine the meaning that the students attributed to the math and to reveal the students' perceptions towards math. Metaphors were also benefited from in order to carry out this aim. The sample of this study was composed of randomly selected 273 students from Yalçin Eskiyapan Middle School located in the district of Keçiören, Ankara in 2015-2016 academic year. When the data obtained from the students were examined, it was seen that the most frequent repeating metaphors were life (38), game (14), book (10), and space (6). The way in which the students explain their metaphors was examined by inductive content analysis. As a result of the analysis, the obtained codes were gathered under four themes as opinions about the content of the math, opinions about the applicability of the math, opinions about the math, and opinions about the teaching of the math. Each theme has two categories, including positive and negative ones.

Recently, people prefer learning information operationally rather than conceptually. In this context, this study was carried out to uncover how preservice math teachers construct in their minds the conceptual definition of limit within the scope of the Calculus Course. The participants of this study consisted of 62 (30 female, 32 male) sophomore students studying in the Elementary Mathematics Teacher Education Department at Uludag University Faculty of Education in the 2016-2017 academic year. Midterm and final exam questions requiring the use of prior knowledge were used to help collect data. Interviews were conducted with three participants who were chosen for their success. In these interviews, five questions were asked by the researchers to uncover the mathematical thinking levels and abstraction processes of the participants. The methods of semi-structured interviews and observations were used to collect data. The data were video-recorded and transcribed. The transcripts were analyzed and interpreted according to the cognitive actions of the RBC-model and the steps in Sfard's theory of mathematics learning. Based on the analysis, the participants were found to be more successful in operational information than in conceptual information. Although the preservice teachers were able to accomplish operational learning, it can be said that they could not fully accomplish conceptual learning because they could not identify algebraic representations and could not use reasoning on these representations. Interviews with the participants revealed that they memorized the characteristics of the concept of limit to be successful in the exams. However, conceptual learning did not take place. Understanding how participants learn is believed to benefit the educators who teach the concept of limit.

The present study aims to examine the extent to which adolescents of immigrant background experience acculturative stress (i.e., cultural clashes with parents and ethnic victimization in school) in multiple contexts, and the reasons why such stress takes a toll on their psychological functioning and views of themselves. The analytic sample includes adolescents of immigrant background residing in Sweden (N = 423, M[subscript age] = 13.19, SD = 0.51). Cluster analysis revealed five distinct groups of adolescents, based on their reports of cultural clashes with parents and ethnic victimization in school: (1) low on both acculturative stressors, (2) average on both acculturative stressors, (3) high on cultural clashes only, (4) high on ethnic victimization only, and (5) high on both acculturative stressors. Mediation analysis showed that adolescents who experienced cultural clashes at home and who were also victimized by their peers in school reported higher levels of feeling in between cultures than adolescents in all the other clusters (except those high on cultural clashes only), and in turn reported higher levels of depressive symptoms and lower levels of self-esteem. The present study highlights the importance of understanding immigrant youth's experiences across multiple contexts simultaneously in order to develop a holistic perspective on their adjustment and integration processes.

Developmental hip dysplasia (DDH) is a disease in which the hip joint fails to develop normally due to various causes before, during or after birth. The most important method used for the detection of DDH is hip ultrasonography. The stage of obtaining the hip US image varies because it depends on the operator and external influences. In this study, an artificial intelligence-based system has been developed to eliminate this variability. The developed system includes a 2-stage deep learning model. The main purpose of the system is to automatically determine whether the US images obtained by physicians are suitable for the calculation of alpha and beta angles required for diagnosis. The system uses the U-NET architecture in the first stage and the masked region-based convolutional neural network (MBT-ESA) architecture in the second stage. For the training, 540 images were taken from Selçuk University Faculty of Medicine hospital with the approval of the ethics committee. A total of 840 images were obtained for training with data augmentation. U-NET architecture training resulted in an accuracy of 0.93 and region-based convolutional neural network training with mask resulted in an accuracy of 0.96. The overall system accuracy was calculated as 0.96. The results obtained in this study suggest that by increasing the number of real-time tests and images, the inter-operator variability in the diagnosis of DDH can be eliminated. [ABSTRACT FROM AUTHOR]

BACKGROUND: Delayed cord clamping is the standard of care for both term and preterm infants worldwide. The aim of this study was to evaluate the effect of 60-second or 180-second delayed cord clamping during labor on cerebral oxygenation and cardiac function. METHODS: Healthy newborns were divided into two groups: a 60-second delay in cord clamping (60-s DCC) and a 180-second delay in cord clamping (180-s DCC) at birth. Pulse oximetry and cerebral near-infrared spectroscopy (cNIRS) probes were placed during postnatal care. A total of 84 healthy newborns were included in this study. Preductal oxygen saturation (SpO2), heart rate, and cNIRS values were recorded at 5 and 10 minutes after delivery. The cardiac function of the infants was assessed by echocardiography at 3–7 days postnatally. RESULTS: There was no significant difference between the groups in SpO2 and cNIRS values at 5 and 10 min. While there was no significant difference in the number of neonates with targeted SpO2 at the 5th and 10th min and targeted cNIRS values at the 10th min, there was a significant difference in the number of neonates with target cNIRS values at the 5th min between groups (p < 0.001). Echocardiographic findings showed that pulmonary flow velocity was increased in the 180-s DCC group; the difference was statistically significant (p = 0.04). CONCLUSION: Our results showed that the number of infants with normal cNIRS values regarding cerebral oxygenation was higher in the 180-s DCC group. The pulmonary flow velocity was significantly increased in the 180-s DCC group in terms of echocardiographic findings. [ABSTRACT FROM AUTHOR]

Copyright of Selçuk University Journal of Faculty of Letters is the property of Selcuk Universitesi Edebiyat Fakultesi Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Forensic Medicine & Forensic Sciences / Türkiye Klinikleri Adli Tıp ve Adli Bilimler Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)