151 results on '"Østergaard, Henrik"'
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2. A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa
3. Computational design of N‐linked glycans for high throughput epitope profiling
4. Engineering of a membrane-triggered activity switch in coagulation factor VIIa
5. Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors
6. Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling
7. Construction of a versatile expression library for all human single-pass transmembrane proteins for receptor pairings by high throughput screening
8. Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex
9. Computational design of N-linked glycans for high throughput epitope profiling
10. Clearance of rFVIIa and NN1731 after intravenous administration to Beagle dogs
11. A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice
12. Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer
13. Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4′-dithiodipyridine
14. Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer
15. Beating tissue factor at its own game: Design and properties of a soluble tissue factor–independent coagulation factor VIIa
16. Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo
17. Wahr de Garr di Bur de kumt - Fra mudder til staten Ditmarsken: Wahr de Garr di Bur de kumt - From mut to the state Dithmarschen
18. A Phase 1/2, First-in-Human, Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Participants with Glanzmann Thrombasthenia
19. Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity
20. Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity
21. Investigation of the mechanism of Tissue Factor-mediated autoactivation of coagulation factor VII
22. Effects on the conformation of FVIIa by sTF and Ca(2+) binding : Studies of fluorescence resonance energy transfer and quenching
23. Protein Engineering and in Vitro Characterization of a Factor VIIa Analog with Selective Abrogation of Tissue Factor Binding
24. Modulating the Antithrombin-Mediated in Vivo Clearance of Coagulation Factor VIIa
25. Proangiogenic TF-FVIIa-PAR2 Signaling Requires Matriptase-Independent Integrin Interaction
26. Risk-based prioritisation of point sources through assessment of the impact on a water supply
27. High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein
28. Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4'-dithiodipyridine.
29. Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa.
30. Crystallization of mutant forms of glutaredoxin Grx1p from yeast
31. Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein
32. Increasing the reactivity of an artificial dithiol-bisulfide pair through modification of the electrostatic milieu
33. Increasing the reactivity of an artificial dithiol-disulfide pair through modification of the electrostatic milieu
34. Antibody-induced Enhancement of Factor VIIa Activity through Distinct Allosteric Pathways
35. Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide
36. Engineering of Substrate Selectivity for Tissue Factor·Factor VIIa Complex Signaling through Protease-activated Receptor 2
37. Erindringer fra Thorstrup Præstegård 1907-1914
38. High-Resolution Imaging of Redox Signaling in Live Cells Through an Oxidation-Sensitive Yellow Fluorescent Protein
39. The Origins of Enhanced Activity in Factor VIIa Analogs and the Interplay between Key Allosteric Sites Revealed by Hydrogen Exchange Mass Spectrometry
40. Generation and biochemical characterization of glycoPEGylated factor VIIa derivatives
41. Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa
42. Crystallization of mutant forms of glutaredoxin Grx1p from yeast
43. Measuring Intracellular Redox Conditions Using GFP-Based Sensors
44. Mechanistic Insight Provided by Glutaredoxin within a Fusion to Redox-Sensitive Yellow Fluorescent Protein
45. Aerobic biodegradation of vinyl chloride and cis-1,2-dichloroethylene in aquifer sediments
46. Increasing the Reactivity of an Artificial Dithiol−Disulfide Pair through Modification of the Electrostatic Milieu
47. Monitoring disulfide bond formation in the eukaryotic cytosol
48. Inhibitory Serpins from Wheat Grain with Reactive Centers Resembling Glutamine-rich Repeats of Prolamin Storage Proteins
49. Identification Of The Coagulation Factor VIIa Integrin Binding Site Essential For Pro-Angiogenic Tissue Factor Signaling
50. A combined structural dynamics approach identifies a putative switch in factor VIIa employed by tissue factor to initiate blood coagulation.
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