50 results on '"Üreyen, Orhan"'
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2. Value of the prognostic nutritional index after liver transplantation of hepatocellular carcinoma patients.
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İnce, Volkan, Üreyen, Orhan, Şentürk, Mustafa, Eyvaz, Kemal, Usta, Sertaç, Carr, Brian, Işık, Burak, and Yılmaz, Sezai
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NUTRITION , *HEPATOCELLULAR carcinoma , *LIVER transplantation , *CANCER-related mortality , *HEALTH outcome assessment - Abstract
Introduction: Hepatocellular carcinoma (HCC) is an important cause of cancer-related deaths in the world. Liver transplantation (LT) is a major treatment option for HCC. Therefore, studies predicting the prognosis of patients after transplantation have special importance. Materials and Methods: Three hundred and ninety-six patients who underwent LT for HCC between March 2006 and November 2021 were enrolled in this study. The prognostic nutritional index (PNI) was analyzed to evaluate its use in the prognosis of patients after LT. Receiver operating curve (ROC) analysis was performed to detect the cutoff values and then logistic regression and survival analyses were performed to identify independent risk factors of prognosis. Results: Overall survival (OS) was 9 years (8.2-9.7), disease-free survival (DFS) was 8.7 years (7.9-9.4) and recurrence was 19%. The median PNI value was 35 (15.7-116). Child-Pugh score-A was significant for DFS (P = 0.042) with a cutoff value of 31.02 in ROC analysis. However, no correlation was found between PNI and either OS, DFS, or recurrence. Conclusion: Pre-operative PNI level may not be a good indicator for predicting the survival or recurrence of HCC patients with LT. Further prospective studies are needed to evaluate the importance of PNI levels in patients with LT for HCC. [ABSTRACT FROM AUTHOR]
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- 2023
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3. Gece ve Gündüz Başvuruya Göre Akut Apandisit
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ÜREYEN, Orhan, primary, ALAGÖZ, Abidin Gazi, additional, KALE, Murat Can, additional, DURSUN, İlhan, additional, İNCİ, Emrehan, additional, and İLHAN, Enver, additional
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- 2022
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4. THE ATTITUDES AND EXPERIENCES OF SURGICAL SCIENCE ACADEMICIANS REGARDING THE OPEN PEER REVIEW PROCESS OF ARTICLES
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Şimşek Keskin, Hatice, İlhan, Enver, Yıldırım, Mehmet, Şenlikçi, Abdullah, and Üreyen, Orhan
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- 2022
5. Sağ Atriumdan Sağ Juguler Vene Yolculuk: Nadir Bir Port Kateter Komplikasyonu
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ÜREYEN, Orhan, primary, FENERCİOĞLU, Hüseyin, additional, ALAY, Demet, additional, DURSUN, İlhan, additional, and İLHAN, Enver, additional
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- 2021
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6. COVİD-19 PANDEMİSİNİN GENEL CERRAHİ KLİNİĞİNDE ACİL VE ELEKTİF CERRAHİ GİRİŞİMLERE OLAN ETKİSİNİN DEĞERLENDİRLİMESİ: KESİTSEL ÇALIŞMA
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İLHAN, Enver, primary, OZTOP, Mehmet, additional, ÜREYEN, Orhan, additional, and YILDIRIM, Mehmet, additional
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- 2020
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7. Post Colectomy and Post Fixation Margin Measurement Correction Factor
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İlhan, Enver, primary, Üreyen, Orhan, additional, Tan, Sedat, additional, Şimşek, Cenk, additional, Erkul, Zehra, additional, Yakan, Savaş, additional, Kızanoglu, Hale, additional, Uslu, Adam, additional, and Yildirim, Mehmet, additional
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- 2020
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8. Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study
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Üreyen, Orhan, primary, Ulusoy, Cemal, additional, Acar, Athan, additional, Sağlam, Fazıl, additional, Kızıloğlu, İlker, additional, Alemdar, Ali, additional, Atahan, Kemal Murat, additional, Dadalı, Emrah, additional, Karaisli, Serkan, additional, Aydın, Mehmet Can, additional, İlhan, Enver, additional, and Güven, Hakan, additional
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- 2020
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9. Pankreasın nadir bir tümörü: Anaplastik karsinom
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Üreyen, Orhan, primary, Ünal, Olçun Ümit, additional, Alay, Demet, additional, Yağcı, Ayşe, additional, and İlhan, Enver, additional
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- 2019
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10. Which more safe in small intestine emergency surgery? İleostomy, anastomosis and primary repair
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Üreyen, Orhan, İlhan, Enver, Uz, Murat, Dadalı, Emrah, Gökçelli, Uğur, and Fenercioğlu, Hüseyin
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Cerrahi işlemler,ileostomi,ince barsak ,Medicine ,Operative procedures,ileostomy,small intestine ,Tıp - Abstract
Giriş: İnce barsak perforasyonları hem hastalar hemde cerrahlar için dünya genelinde önemli cerrahi sorunlardan birisidir. Tedavi seçiminde farklı cerrahi prosedürler uygulanabilmekte olup henüz kesinleşmiş bir seçenek yoktur. Gereç ve yöntemler: Acil ince barsak patolojisine bağlı ameliyat edilen olgular çalışmaya dahil edildi. Olgular yapılan cerrahi tipine göre ince barsak anastomozu yapılan (Grup I), ileostomi açılan (Grup II) ve primer tamir yapılanlar (Grup III) olarak gruplandırıldı. Bulgular: Toplam 107 olgu çalışmaya dahil edildi. Gruplar arası mortalite oranları Grup I’de %23, Grupta II’de %52 ve Grup III’te %39 idi ve aralarında anlamlı farklılık saptandı(p, Introduction: Small intestine perforations are one of the major surgical problems in the worldwide for both patients and surgeons. Different surgical procedures can be applied in the choice of treatment and there is no definite option yet. Materials and methods: The cases who operated due to emergency small intestine pathology were included in the study. The cases were grouped according to the type of surgery: small intestinal anastomosis (Group I), ileostomy opened (Group II) and primary repair (Group III). Results: A total of 107 cases were included in the study. The mortality rates between the groups were 23% in Group I, 52% in Group II and 39% in Group III and there was a significant difference between them (p
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- 2018
11. Comparison of Nutritional Status with Clinical Status, Laboratory Results and NRS-2002 Score in Patients Requiring Nutritional Support
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Üreyen, Orhan, primary, Ergül Kunduracı, Yasemin, additional, Bulut, Yeter, additional, İnal, Canan, additional, and Ortan, Pınar, additional
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- 2019
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12. Prevention of Peritoneal Adhesions by Non-Thermal Dielectric Barrier Discharge Plasma Treatment on Mouse Model: A Proof of Concept Study
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Gökçelli, Uğur, primary, Ercan, Utku Kürşat, additional, İlhan, Enver, additional, Argon, Asuman, additional, Çukur, Elif, additional, and Üreyen, Orhan, additional
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- 2019
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13. Predictive Factors in Incidental Thyroid Carcinoma: A Retrospective Study
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Üreyen, Orhan, primary, Alay, Demet, additional, Fenercioğlu, Hüseyin, additional, Öztürk, Rafet Güneş, additional, Adıbelli, Zehra Hilal, additional, and İlhan, Enver, additional
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- 2019
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14. Pneumoretroperitoneum, pneumomediastinum, pneumothorax and subcutaneous emphysema after diagnostic colonoscopy
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Kavurmacı, Önder, primary, Türker, Asuman Akın, additional, Alkan, Bülent, additional, Üreyen, Orhan, additional, and Tekeli, Mehmet Tahsin, additional
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- 2019
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15. Axillary metastasis in clinically node-negative breast cancer
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Üreyen, Orhan, primary, Çavdar, Demet Kocatepe, additional, Adıbelli, Zehra Hilal, additional, and İlhan, Enver, additional
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- 2018
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16. Prevention of Peritoneal Adhesions by Non-Thermal Dielectric Barrier Discharge Plasma Treatment on Mouse Model: A Proof of Concept Study.
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Gökçelli, Uğur, Ercan, Utku Kürşat, İlhan, Enver, Argon, Asuman, Çukur, Elif, and Üreyen, Orhan
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PLASMA flow ,PROOF of concept ,ADHESION ,NON-thermal plasmas ,PLASMA confinement ,TISSUE adhesions - Abstract
Purposes: Formation of peritoneal adhesions is a common consequence of abdominopelvic surgeries and remarkably increases the mortality and morbidity. Moreover, peritoneal adhesions linked to chronic abdominopelvic pain and infertility in women. Various attempts for prevention of peritoneal adhesions were reported. However, these methods either remain insufficient to prevent formation of peritoneal adhesions or carry some practical limitations and thus, there is a need for novel techniques that could effectively decrease the formation of peritoneal adhesions. The aim of the present prospective, randomized, controlled, and single blinded study was to evaluate the effect of non-thermal atmospheric plasma (NTAP) treatment on prevention of peritoneal adhesions. Materials and Methods: Sixteen male CD-1 mice were randomly divided into two groups: control and plasma. Excisional and abrasion adhesion models were generated on the peritoneal side wall and cecum, respectively. Ten days after creating adhesion models, mice were sacrificed and adhesion formations were evaluated macroscopically using Knightly's and Linsky's grading systems to assess the intensity and extent of adhesions, respectively. Zühlke's grading system was used for microscopic assessment of adhesions. Results: The mean scores for peritoneum and cecum in control group according to Knightly's grading system were determined as 3.3 and 2.6, respectively. In NTAP-treated group, Knightly's score was determined as 1.6 and 0.5 for peritoneum and cecum, respectively. NTAP treatment reduced Linsky's score from 3.8 to 1.3 and 2.1 to 1.1 on peritoneum and cecum. Finally, in microscopic evaluation, NTAP treatment reduced Zühlke's score from 3.4 to 1.5 and 2.6 to 1.3 for peritoneum and cecum, respectively. Conclusions: The results of the present proof of concept study suggest that NTAP could be a novel method to reduce and/or prevent the formation of peritoneal adhesions after abdominopelvic surgeries. [ABSTRACT FROM AUTHOR]
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- 2020
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17. Hem-o-lok clips versus intracorporeal knotting for the closure of the appendix stump in laparoscopic appendectomy: A prospective randomized study.
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Üreyen, Orhan, Tan, Sedat, Dadalı, Emrah, Yıldırım, Mehmet, and İlhan, Enver
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AGE distribution ,APPENDECTOMY ,APPENDICITIS ,COST effectiveness ,LENGTH of stay in hospitals ,LAPAROSCOPIC surgery ,LONGITUDINAL method ,MEDICAL care costs ,RELIABILITY (Personality trait) ,SEX distribution ,SURGICAL complications ,SUTURING ,PAIN measurement ,BODY mass index ,RANDOMIZED controlled trials ,PREOPERATIVE period ,TREATMENT duration - Abstract
Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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18. Evaluation of Factors Associated with Anastomotic Leakage in Colorectal Surgery
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Üreyen, Orhan, primary, İlhan, Enver, additional, Dadalı, Emrah, additional, Gökçelli, Uğur, additional, Alay, Demet, additional, Bağrıaçık Altıntaş, Semra, additional, and Tekeli, Mehmet Tahsin, additional
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- 2018
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19. Mihmanlı’nın MİDE KANSERİ VE CERRAHİ TEDAVİSİ’’ 3. Baskı
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ERKAN, NAZİF, DİKMEN, KÜRŞAT, DEMİRYILMAZ, İSMAİL, DEMİRCİ, SALİM, DEMİR, UYGAR, DAYANGAÇ, MURAT, DALDAL, EMİN, ÇOBANOĞLU, NESRİN, ÇETİN, RECEP, ÇETİN, MELTEM, ÇAKIR, MURAT, CARTI, ERDEM BARIŞ, BURAN, TAHİR, BÖREKÇİ, İSMAİL, BOSTANCI, ÖZGÜR, BOSTANCI, HASAN, BOSTANCI, ERDAL BİROL, BORA, SEYMEN, BAYAR, SANCAR, ATİLA, KORAY, ATICI, ALİ EMRE, ARSLAN, KEMAL, ALPDOĞAN, ÖZCAN, ALEMDAR, ALİ, ALBAYRAK, DOĞAN, AKBAYIR, NİHAT, ZENGEL, BAHA, MİHMANLI, İSMAİL, NACAR, TUNCER, OKAN, İSMAİL, OYMACI, ERKAN, ÖZBAYIR, TÜRKAN, YÜKSEL, OSMAN, YOLDAŞ, TAYFUN, YILDIRIM, MEHMET, ÖZER, MUSTAFA TAHİR, ÖZKEÇECİ, ZİYA TANER, ÖZKÖK, SERDAR, ÖZSOY, ZEKİ, POLAT, COŞKUN, SAĞLAM, FAZIL, YEŞİLYURT, SİNEM, SAKIZ, DAMLANUR, SASAKO, MİTSURU, SEZER, TAYLAN ÖZGÜR, SERT, FATMA, SÖKMEN, MEHMET, SÖKMEN, SELMAN, SÖZÜER, ERDOĞAN MÜTEVELLİ, SULAİMANOV, MARLEN, ŞAHİN, ABDURAHMAN, ŞAHİN, MUSTAFA, TAVLI, SÜLEYMAN ŞAKİR, TOPALOĞLU, ÜMİT, UÇAR, AHMET DENİZ, UĞUZ, ALPER, ULAŞ, HALİS, USLU, ADAM, USLU, RÜÇHAN, ÜNAL, ALİ EKREM, ÜREYEN, ORHAN, VARDAR, ENVER, VARDAR, RUKİYE, YAKAN, SAVAŞ, YALAZ, SEYHAN, YAVUZ, GİRAY, MİHMANLI, MEHMET, KÜÇÜK, CAN, KOZAK, ORHAN, KORMAN, UĞUR, KATAİ, HİTOSHİ, KASAP, ELMAS, KARAVELİ ÇAKIR, SELDA, KARASU, ŞEBNEM, KAPLAN, HASAN, KANTARCI, FATİH, KALAYCI, ORHAN, İŞGÖR, ADNAN, İSMAYİLOV, İLKİN, İPEK, TURGUT, İLHAN, ENVER, IŞIK, ARDA, HYUNG, WOO JIN, HOT, SEMİH, HOŞCOŞKUN, ZEKİ, GÜVEN, HAKAN, GÜNER, ALİ, GÜLER, ADEM, GÜL, MUSTAFA, FERAHKÖŞE, ZAFER, ERYAVUZ, YAVUZ, ERSİN, MUHTAR SİNAN, ERDOĞAN, ATİKE PINAR, EMİROĞLU, MUSTAFA, and DURAN, EYÜP
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- 2016
20. Neuroendocrine tumor of the rectum detected incidentally: A case report
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Üreyen, Orhan, primary, İlhan, Enver, additional, Gökçelli, Uğur, additional, and Vardar, Enver, additional
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- 2017
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21. İnkarsere karın duvarı fıtıklı hastalarda morbidite ve mortaliteyi etkileyen faktörler
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Dadalı, Emrah, Şenlikçi, Abdullah, İlhan, Enver, Mehmet Akif, Üstüner, ŞİMŞEK KESKİN, HATİCE, Güngör, Hilmi, Tekeli, Mehmet Tahsin, Üreyen, Orhan, Cengiz, Fevzi, Yakan, Savaş, and Gökçelli, Uğur
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- 2015
22. Evaluation of patients with breast cancer 40 years of age and under and 70 years of age and older
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Üreyen, Orhan, primary, İlhan, Enver, additional, Dadalı, Emrah, additional, and Gökçelli, Uğur, additional
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- 2016
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23. A rare cause of acute abdomen: ruptured acquired jejunoileal diverticulitis in a patient with Crohn's disease
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GÖKAKIN, Ali, ATABEY, Mustafa, ÜREYEN, Orhan, ALTINEL, Özcan, and TEZCAN, Eyüp
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Crohn hastalığı,divertikülozis,divertikülitis,rüptür ,Crohn’s disease,diverticulosis,diverticulitis,rupture - Abstract
The objective of case report is to present a case of ruptured acquired jejunoileal diverticulitis in a patient with acquired small intestinal diverticulosis and Crohn's disease. Acquired small intestinal diverticulosis are extremely rare clinical entities. They only become surgically relevant when the complications such as diverticulitis, perforation and bleeding occurs. Crohn's disease has been reported to be in close association with several small intestine pathologies including Meckel's diverticulum. However, the association between Crohn's disease and acquired small intestinal diverticulosis has not been reported previously. The patient was 35-year-old man. Three days ago before admission, by means of colonoscopy and biopsy, he was diagnosed as having Crohn's disease and begun to use a treatment for this disease. On admission, he complained about abdominal pain. Ultrasonography revealed that there was free fluid in all quadrant of abdominal cavity. The patient was referred for surgery. At laparotomy, there was multiple diverticulosis in small intestine from ileocecal valve to Treitz .One of them was ruptured. We performed segmental small bowel resection and end-to-end anastomosis. He was discharged uneventfully. As a conclusion this case suggests that small intestinal diverticulosis and its complications may be associated with Crohn's disease and should be considered in the differential diagnostic workup and surveillance of patients with gastrointestinal disorders. Imaging studies including entroclysis, technetium scan (for exclusion of Meckel's diverticulum) and computerized tomography may be useful to make a definitive diagnosis of both the Crohn's disease and diverticulosis. However, some patients may require laparotomy not only for a final diagnosis but also for the complications.Keywords: Crohn's disease, diverticulosis, diverticulitis, ruptureÖzetBu olgu sunumunun amacı Crohn hastalığı ve edinsel ince bağırsak divertikülozu olan bir hastada gelişen jejenoileal divertikülit perforosyonunu sunmaktır. Edinsel ince bağırsak divertikülozu oldukça nadir görülen bir klinik durumdur. Cerrahinin gündemine yalnızca divertikülit, perforasyon ve kanama gibi komplikasyonlar ortaya çıktığında gelir. Crohn hastalığını Meckel divertikülü gibi bası ince bağırsak hastalıkları ile olan yakın ilişkisi daha önceden bildirilmiştir. Ancak, Crohn hastalığı ile edinsel ince bağırsak divertikülozu ilişkisi daha önce gösterilmemiştir. Karın ağrısı şikayeti ile başvuran 35 yaşında erkek hastanın hikayesinden üç gün önce kolonoskopi ve biyopsi neticesinde Crohn hastalığı teşhisi konulduğu ve bu hastalığa yönelik tedaviye başlandığı öğrenildi. Yapılan abdominal ultrasonografide batın içi tüm kadranlarda serbest sıvı görülmesi üzerine hasta cerrahi kararı alındı. Laparatomide ileoçekal valfden Treitz ligamanına kadar ince bağırsakda multiple divertiküller görüldü. Bu divertiküllerden birinde rüptür mevcuttu. Hastaya segmenter ince bağırsak rezeksiyonu ve uç uca anastomoz yapıldı. Operasyon sonrası dönem olaysız geçti ve hasta taburcu edildi. Sonuç olarak bu olgu ince bağırsak divertikülozu ve komplikasyonlarının Crohn hastalığı ile ilişkisi olabileceğini gastrointestinal sistem yakınmaları olan hastalara yaklaşımda ve teşhis çalışmaları esnasında bu durumun göz önüne alınması gerektiğini düşündürdü. Entroklisiz, teknesyum taraması ( Mekel divertikülünü dışlamak için) ve abdominal tomografi Crohn hastalığı ve ince bağırsak divertikülozu kesin tanısında yararlı olabilir. Ancak bazı hastalarda gerek tanı gerekse de komplikasyonları tedavi etmek amacı ile laparatomi gerekebilir.Anahtar sözcükler: Crohn hastalığı, divertikülozis, divertikülitis, rüptür, Bu olgu sunumunun amacı Crohn hastalığı ve edinsel ince bağırsak divertikülozu olan bir hastada gelişen jejenoileal divertikülit perforosyonunu sunmaktır. Edinsel ince bağırsak divertikülozu oldukça nadir görülen bir klinik durumdur. Cerrahinin gündemine yalnızca divertikülit, perforasyon ve kanama gibi komplikasyonlar ortaya çıktığında gelir. Crohn hastalığını Meckel divertikülü gibi bası ince bağırsak hastalıkları ile olan yakın ilişkisi daha önceden bildirilmiştir. Ancak, Crohn hastalığı ile edinsel ince bağırsak divertikülozu ilişkisi daha önce gösterilmemiştir. Karın ağrısı şikayeti ile başvuran 35 yaşında erkek hastanın hikayesinden üç gün önce kolonoskopi ve biyopsi neticesinde Crohn hastalığı teşhisi konulduğu ve bu hastalığa yönelik tedaviye başlandığı öğrenildi. Yapılan abdominal ultrasonografide batın içi tüm kadranlarda serbest sıvı görülmesi üzerine hasta cerrahi kararı alındı. Laparatomide ileoçekal valfden Treitz ligamanına kadar ince bağırsakda multiple divertiküller görüldü. Bu divertiküllerden birinde rüptür mevcuttu. Hastaya segmenter ince bağırsak rezeksiyonu ve uç uca anastomoz yapıldı. Operasyon sonrası dönem olaysız geçti ve hasta taburcu edildi. Sonuç olarak bu olgu ince bağırsak divertikülozu ve komplikasyonlarının Crohn hastalığı ile ilişkisi olabileceğini gastrointestinal sistem yakınmaları olan hastalara yaklaşımda ve teşhis çalışmaları esnasında bu durumun göz önüne alınması gerektiğini düşündürdü. Entroklisiz, teknesyum taraması ( Mekel divertikülünü dışlamak için) ve abdominal tomografi Crohn hastalığı ve ince bağırsak divertikülozu kesin tanısında yararlı olabilir. Ancak bazı hastalarda gerek tanı gerekse de komplikasyonları tedavi etmek amacı ile laparatomi gerekebilir.
- Published
- 2013
24. The effect of Resveratrol and Octreotide on peritoneal adhesions in a rat model.
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ÜREYEN, Orhan, ÜSTÜNER, Mehmet Akif, ARGON, Asuman, ÖZBILGIN, Mücahit, EGELI, Tufan, İLHAN, Enver, VARDAR, Enver, ÜNEK, Tarkan, YILDIRIM, Mehmet, and ERKAN, Nazif
- Abstract
Introduction: The aim of this study was to investigate the efficacy of resveratrol and octreotide, agents that are used to prevent intra-abdominal adhesions in experimental models, in preventing intraperitoneal adhesions when used alone or in combination. Materials and Methods: The study employed 28 young female Wistar albino rats weighing 250-300 grams. An experimental adhesion model was created in each rat using serosal abrasion and peritoneal excision. They were divided into four groups, each comprising seven rats: Group 1, adhesion induction only; Group 2, resveratrol administration only; Group 3, octreotide administration only; and Group 4, administration of resveratrol and octreotide combination. The rats were monitored under appropriate conditions for 14 days and then underwent laparotomy. Macroscopic intensity and extensiveness of adhesions and microscopic changes in the granulation tissue (cellular intensity, reticular and collagen fibers, capillaries, elastic and smooth muscle fibers, fibrosis) were evaluated and graded. Kruskal-Wallis and Mann-Whitney U-test were used in statistical analysis and the level of statistical significance was established as p <0.05. Results: There was no significant difference between the groups in terms of the intensity and extensiveness of macroscopic adhesions (p=0.377 and p=0.319). There was a statistically significant difference between the microscopic scores of the groups according to Zühlke's classification (p=0.026). The Bonferroni correction used to test for the differences revealed that the rats in Group 1 achieved significantly higher scores than the rats in Group 3 (p=0.016). Conclusion: Octreotide showed higher efficiency compared to the control group in microscopic classification; however, the two agents were not superior to each other or their combination was not superior in preventing intra-abdominal adhesions. [ABSTRACT FROM AUTHOR]
- Published
- 2018
25. Survival outcomes after D1 and D2 lymphadenectomy with R0 resection in stage II-III gastric cancer: Longitudinal follow-up in a single center.
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Uslu, Adam, Zengel, Baha, İlhan, Enver, Aykas, Ahmet, Şimşek, Cenk, Üreyen, Orhan, Duran, Ali, and Okut, Gökalp
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LYMPHADENECTOMY ,STOMACH cancer treatment ,ONCOLOGIC surgery ,FOLLOW-up studies (Medicine) ,GASTRECTOMY - Abstract
Objective: D2 lymphadenectomy (D2-LND) with curative resection (R0) is the cornerstone of gastric cancer treatment. In this study, we compared survival outcomes of D2-LDN with D1-LDN in patients who had undergone curative resection for Stages II and III primary gastric adenocarcinoma. Material and Methods: Between April 1996 and March 2014, 153 consecutive patients with adenocarcinoma of the stomach underwent total gastrectomy with D1-LND or D2-LND. Among those, 118 patients (38 D1 vs. 80 D2) with a complete history and having been followed for at least 1 year after surgery were enrolled. Both groups were compared in terms of demographic and clinico-pathologic characteristics. Results: The mean follow-up was 42.6±52.5 months (mo.). The demographic characteristics of the groups were similar. The Tumor, Node and Metastases (TNM) stage distribution was 25% for Stage II and 75% for Stage III for both groups. Eighteen patients (47.4%) in the D1 and 47 patients (58.8%) in the D2 group were free from locoregional recurrence. The median disease-free survival was 22.0±4.1 mo. for the D1 and 28.0±4.3 mo. for the D2 group (p=0.36). Eight patients (21%) in the D1 and 39 patients (49%) in the D2 group were alive at the last follow-up. The median overall survival (OS) was 22.0±3.7 mo. for the D1 and 31.0±5.4 mo. for the D2 group (p=0.13). The 5-yeardisease- free survival and OS by the Kaplan-Meier estimates were 41% vs. 51% and 30% vs.42% in the D1 and D2 groups, respectively. The median 5-year OS for patients with Stages IIIB and IIIC tumors was 14.0±2.2 mo.for the D1 and 20.0±5.0 mo. for the D2 group, respectively (p: 0.048). Conclusion: When compared to D1-LND, D2-LND with R0 resection have yielded a trend toward a better outcome in patients with primary gastric adenocarcinoma. [ABSTRACT FROM AUTHOR]
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- 2018
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26. Non-operative management of abdominal gunshot injuries: Is it safe in all cases?
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İflazoğlu, Nidal, Üreyen, Orhan, Öner, Osman Zekai, Meral, Ulvi Mehmet, and Yülüklü, Murat
- Subjects
- *
GUNSHOT wounds , *ABDOMINAL surgery , *COMPUTED tomography , *BLOOD transfusion , *ABDOMINAL pain , *THERAPEUTICS - Abstract
Objective: In line with advances in diagnostic methods and expectation of a decrease in the number of negative laparotomies, selective non-operative management of abdominal gunshot wounds has been increasingly used over the last three decades. We aim to detect the possibility of treatment without surgery and present our experience in selected cases referred from Syria to a hospital at the Turkish-Syrian border. Material and Methods: Between February 2012 and June 2014, patients admitted with abdominal gunshot wounds were analyzed. Computed tomography was performed for all patients on admission. Patients who were hemodynamically stable and did not have symptoms of peritonitis at the time of presentation were included in the study. The primary outcome parameters were mortality and morbidity. Successful selective non-operative management (Group 1) and unsuccessful selective non-operative management (Group 2) groups were compared in terms of complications, blood transfusion, injury site, injury severity score (ISS), and hospital stay. Results: Of 158 truncal injury patients, 18 were considered feasible for selective non-operative management. Of these, 14 (78%) patients were treated without surgery. Other Four patients were operated upon progressively increasing abdominal pain and tenderness during follow-up. On diagnostic exploration, all of these cases had intestinal perforations. No mortality was observed in selective non-operative management. There was no statistically significant difference between Group 1 and Group 2, in terms of length of hospital stay (96 and 127 h, respectively). Also, there was no difference between groups in terms of blood transfusion necessity, injury site, complication rate, and injury severity score (p>0.05). Conclusion: Decision making on patient selection for selective non-operative management is critical to ensure favorable outcomes. It is not possible to predict the success of selective non-operative management in advance. Cautious clinical examination and close monitoring of these patients is vital; however, emergency laparotomy should be performed in case of change in vital signs and positive symptoms concerning peritonitis. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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27. Original research-Orijinal araştırma
- Author
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MUSLU, Ümran, GÖKAKIN, Ali, DEMİR, Ayşegül, ÜREYEN, Orhan, ALTINEL, Özcan, TEZCAN, Eyüp, ATABEY, Mustafa, AKGÖL, Gündüz, GENÇ, Hüdai, and Sivas Cumhuriyet Üniversitesi
- Subjects
Acil cerrahi,peptik ülser perforasyonu,akut karın ağrısı ,General Medicine ,Cerrahi - Abstract
Aim. The efficacy of modern medical treatment has played an important role in decreased incidence and differentation of the epidemiology of ulcer perforation. But a similar rate of differentiation in mortality and morbidity was not observed. The effect of more simple surgical procedures and the factors associated with mortality and morbidity in ulcer perforation, were the subject of this study. Methods. The files of 126 patients who were operated due to peptic ulcer perforation between 1998 and 2005 were analyzed in retrospective manner. Patients were divided into two groups as primary repair group and definitive surgery group. Factors affecting the choice of surgical treatment, perforation etiology, predisposing factors associated with mortality and morbidity rate were evaluated. Results. A hundred and fourteen 114 (90.5%) patients were male and 12 (9.5%) of them were female. The mean age was 50.7 (± 13.5). Primary repair group included 103 (81.7%) patients whereas definitive surgery group included 23 (18.3%) patients. The overall mortality and morbidity rates in primary repair group and definitive surgery were, 3.9% and 15% respectively. Conclusion. Primary repair has re-gained popularity in time. The factors associated with mortality and morbidity were age, concomitant disease, and delayed admission. Keywords: Urgent surgery, peptic ulcer perforation, acute abdominal pain Özet Amaç. Modern tedavi ile medikal peptik ülser perforasyonu insidansının azalmasına ve ülser perforasyonu epidemiyolojisinin değişmesine karşın, perforasyonlara bağlı ölüm oranlarında benzer azalma sağlanamamıştır. Bu çalışmada peptik ülser perforasyonunda gözlenen morbidite ve mortalite ile ilişkili faktörler ve daha basit cerrahi işlemlerin rolü irdelenmiştir. Yöntem. Ocak 1998-Aralık 2005 yılları arasında peptik ülser perforasyonu nedeniyle opere edilen 126 hasta, arşiv kayıtlarından retrospektif olarak incelendi. Hastalar, primer tamir ve kesin cerrahi uygulananlar olarak ikiye ayrıldı. Uygulanacak cerrahi tipini etkileyen faktörler, perforasyon etyolojisi, mortalite ve morbiditeyi etkileyen faktörler değerlendirildi. Bulgular. Hastaların 114 (%90,5)’ ü erkek, 12 (%9,5)’ si kadın olup yaş ortalaması 50,7 (±13,5) idi. Hastaların 103 (%81,7)’üne primer sütür, 23 (%18,3)’üne kesin ülser cerrahisi uygulandı. Genel mortalite oranı %3,9, genel morbidite oranı ise %15 idi. Hastaların mortalite ve morbidite ile ilişkili risk faktörlerinin yaş (>60), yandaş hastalığın varlığı ve hastaneye geç başvuru olduğu saptandı Sonuç. Peptik ülser perforasyonu cerrahisinde primer tamir zamanla yeniden popular olmuştur. Hastaneye geç başvuru, yaş, eşlik eden hastalık ve operasyon tipi morbidite ve mortalite ile ilişkili faktörler olarak bulundu. Anahtar sözcükler: Acil cerrahi, peptik ülser perforasyonu, akut karın ağrısı, Amaç. Modern tedavi ile medikal peptik ülser perforasyonu insidansının azalmasına ve ülser perforasyonu epidemiyolojisinin değişmesine karşın, perforasyonlara bağlı ölüm oranlarında benzer azalma sağlanamamıştır. Bu çalışmada peptik ülser perforasyonunda gözlenen morbidite ve mortalite ile ilişkili faktörler ve daha basit cerrahi işlemlerin rolü irdelenmiştir. Yöntem. Ocak 1998-Aralık 2005 yılları arasında peptik ülser perforasyonu nedeniyle opere edilen 126 hasta, arşiv kayıtlarından retrospektif olarak incelendi. Hastalar, primer tamir ve kesin cerrahi uygulananlar olarak ikiye ayrıldı. Uygulanacak cerrahi tipini etkileyen faktörler, perforasyon etyolojisi, mortalite ve morbiditeyi etkileyen faktörler değerlendirildi. Bulgular. Hastaların 114 (%90,5)’ ü erkek, 12 (%9,5)’ si kadın olup yaş ortalaması 50,7 (±13,5) idi. Hastaların 103 (%81,7)’üne primer sütür, 23 (%18,3)’üne kesin ülser cerrahisi uygulandı. Genel mortalite oranı %3,9, genel morbidite oranı ise %15 idi. Hastaların mortalite ve morbidite ile ilişkili risk faktörlerinin yaş (>60), yandaş hastalığın varlığı ve hastaneye geç başvuru olduğu saptandı Sonuç. Peptik ülser perforasyonu cerrahisinde primer tamir zamanla yeniden popular olmuştur. Hastaneye geç başvuru, yaş, eşlik eden hastalık ve operasyon tipi morbidite ve mortalite ile ilişkili faktörler olarak bulundu
- Published
- 2012
28. Usefulness of FGSI and UFGSI scoring systems for predicting mortality in patients with Fournier's gangrene: A multicenter study.
- Author
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Üreyen, Orhan, Acar, Atahan, Gökçelli, Uğur, Atahan, Murat Kemal, and İlhan, Enver
- Subjects
MORTALITY risk factors ,MEDICAL cooperation ,PROGNOSIS ,RESEARCH ,COMORBIDITY ,FOURNIER gangrene - Abstract
Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
- Full Text
- View/download PDF
29. A rare cause of acute abdomen: ruptured acquired jejunoileal diverticulitis in a patient with Crohn's disease
- Author
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Gökakın, Ali Kağan, primary, Atabey, Mustafa, additional, Üreyen, Orhan, additional, Altınel, Özcan, additional, and Tezcan, Eyüp Sabri, additional
- Published
- 2013
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30. Mortality and morbidity risk factors in the surgery of peptic ulcer perforation
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Muslu, Umran, primary, Gökakın, Ali Kaan, additional, Demir, Ayşegül, additional, Üreyen, Orhan, additional, Altınel, Özcan, additional, Tezcan, Eyüp Sabri, additional, Atabey, Mustafa, additional, Akgöl, Gündüz, additional, and Genç, Hüdia, additional
- Published
- 2012
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31. A Retrospective Comparative Study of Image-Guided Excisional Biopsy in High-Risk Non-Palpable Breast Lesions: Predictive Factors for Malignancy.
- Author
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İflazoğlu, Nidal, Üreyen, Orhan, Atahan, Murat Kemal, Meral, Ulvi Mehmet, Sezgin, Gülten, and Tarcan, Ercüment
- Subjects
- *
BREAST , *BREAST cancer risk factors , *BREAST cancer diagnosis , *BREAST cancer treatment , *BIOPSY , *MEDICAL screening , *RETROSPECTIVE studies , *COMPARATIVE studies , *WOUNDS & injuries - Abstract
Objective: The use of mammography (MM) in breast cancer screening programs has been increasing in recent years. Thus, increasing the number of detected nonpalpable breast cancer patients, through early diagnosis and treatment also increased survival rates. In our study, we wanted to share the factors about imagingguided exicional biopsies for non-palpable breast lesions in postoperative proven breast carcinoma patients. Materials and Methods: The surgical data were reviewed for 83 patients with non-palpabl high-risk breast lesions undergoing imaging-guided surgery in our department between January, 2006 and May, 2011. Histopathologic results and age, ultrasound(US) results, MM image results, BI-RADS categorization, localization of lesion(quadrant) were assessed and factors for predicting malignity were detected. Results: Median age was 52 (age range 32-80 years). 29 (34,9%) of patients were malign in histopathologic results. In four patient, re-excision performed because of positive surgical margins. Axillary examination results were normal in 24 (82,7%) of malignant patients. In MM examination; microcalcifications and nodular opasity were diagnosed in 74,6% of patients before surgery. There were no differance about malignity in these groups after surgery (p:0,428). 59% and 32,7% of patients were BI-RADS 4 and 3, respectively. Postoperative diagnosed malignancies in BI-RADS 4 group were significantly higher than BI-RADS 3 group (p:<0,001). Conclusion: In our study; we concluded that, preoperative BI-RADS categorization (US and MM) is correlated with histopathologic findings after surgery and imaging-guided breast surgery is effective for diagnosis of early-stage breast carcinoma. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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32. İnkarsere Karın Duvarı Fıtıklı Hastalarda Morbidite ve Mortaliteyi Etkileyen Faktörler.
- Author
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İlhan, Enver, Üstüner, Mehmet Akif, Şenlikci, Abdullah, Dadalı, Emrah, Gökçelli, Uğur, Şimşek, Hatice, Yakan, Savaş, Cengiz, Fevzi, Üreyen, Orhan, Tekeli, Mehmet Tahsin, and Güngör, Hilmi
- Abstract
Copyright of Konuralp Medical Journal / Konuralp Tip Dergisi is the property of Duzce University Medical School and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
33. LÖKOSİT SAYISI VE C-REAKTİF PROTEİNİN AKUT APANDİSİT TANISINA KATKISI: BİR İLÇE HASTANESİ DENEYİMİ.
- Author
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IŞIK, Özgen, ÜREYEN, Orhan, and ORUÇ, Cem
- Abstract
To determine if white blood cell count and C-reactive protein contribute the diagnosis of acute appendicitis in a town hospital that is far away high-volume centers.Patients who underwent appendectomy between January 2011 and June 2012 reviewed retrospectively. Patients who were performed appendectomy as a secondary of another operation excluded from the study. Patients distributed into two groups: appendicitis and negative appendectomy.65 patients were performed open appendectomy while other 5 patients underwent laparoscopic appendectomy. Negative appendectomy rate was 14.3%. Both mean white blood cell counts (p<0.01) and C-reactive protein levels (p=0.02) were significantly different for two groups. However, the highest specificity (90%) was obtained when both of them raised. 6 patients had morbidities in the postoperative course, and the mean length of hospital stay was 2.3 days.White blood cell count and C-reactive protein level are simple tests that can be worked in many centers; however, they can only facilitate acute appendicitis diagnosis when they interpreted with clinical findings. Possibility of acute appendicitis is very low, in a patient who admits emergency department with low right abdominal pain, when both tests are in normal ranges. We believe that observation with re-evaluation in certain intervals would contribute on reducing negative appendectomy rate even in centers with limited facilities. [ABSTRACT FROM AUTHOR]
- Published
- 2015
34. Extra-adrenal myelolipoma with hemolytic anemia.
- Author
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İflazoğlu, Nidal, Üreyen, Orhan, and Keleş, Mahir
- Subjects
- *
BENIGN tumors , *HEMOLYTIC anemia , *RETROPERITONEUM , *ADRENAL cortex , *ADIPOSE tissues , *TUMORS - Abstract
Myelolipomas are rare benign tumors often detected as adrenal masses. Extra-adrenal myelolipomas are encountered even more rarely. The rate of detection of these lesions is increasing with improved radiological techniques. Because of their localization and morphological similarities to well differentiated liposarcomas, extra-adrenal myelolipomas need to be differentiated from other aggressive neoplasms. Preoperative imaging and percutaneous biopsy are important tools in the diagnosis of these lesions. We report a very rare case of an extra-adrenal perirenal myelolipoma associated with hemolytic anemia. The etiology, differential diagnosis, and treatment options for the lesion have been discussed. Fat-containing tumors of the retroperitoneum should be considered in the differential diagnosis. Accurate diagnosis is important to avoid over-treatment of these benign lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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35. RADYOLOJİK OLARAK BI-RADS SINIFLAMASINA GÖRE MEMEDEKİ KİTLELERE YAKLAŞIM NE OLMALI? HİSTOPATOLOJİK SONUÇLARLA KARŞILAŞTIRMA.
- Author
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Üreyen, Orhan, İlhan, Enver, Adıbelli, Zehra Hilal, Üstüner, Mehmet Akif, Şenlikçi, Abdullah, Dadalı, Emrah, Gökçelli, Uğur, Yağcı, Ayşe, and Güngör, Hilmi
- Subjects
- *
BIOPSY , *MAMMOGRAMS , *BREAST tumors , *MAGNETIC resonance imaging , *MEDICAL records , *ULTRASONIC imaging , *RETROSPECTIVE studies , *DESCRIPTIVE statistics - Abstract
Purpose: BI-RADS 3 and 4 constitute the most debated group of the BI-RADS classification used in the evaluation of breast masses. The aim of the present study was to compare radiological and histopathological results of the patients who were radiological determined as BI-RADS 3, 4 or 5, and who underwent biopsy, and to review proper approach to such lesions. Methods: The medical charts of the patients who were found to have a breast mass on physical examination and/or using radiological investigation between January 2011 and August 2013, and who were classified as BI-RADS 3, 4 or 5 using ultrasonography, mammography, and/or magnetic resonance imaging, and who subsequently underwent biopsy examination were retrospectively reviewed. Results: A total of 97 patients were included in the study. Of the cases in BI-RADS 3 group, 11% had malignant lesion, 58.8% of the patients in the BI-RADS 4 group had malignant lesion, and all patients in the BI-RADS 5 group had malignant lesion. When the patients in BI-RADS 4 were divided into subgroups, the rate of malignant was 23% in the 4A group and 88% in the 4C group. Conclusion: The lesions in BI-RADS 3 group often have benign character, but it must be remembered that they may be rarely malignant lesions. In BI-RADS 4 group, the lesions in 4A have low malignancy potential and the lesions in 4C group have extremely high malignancy potential. [ABSTRACT FROM AUTHOR]
- Published
- 2014
36. Co-existent breast and renal cancer.
- Author
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Üreyen, Orhan, Dadalı, Emrah, Akdeniz, Fırat, Şahin, Tamer, Tekeli, Mehmet Tahsin, Eliyatkın, Nuket, Postacı, Hakan, and İlhan, Enver
- Abstract
The concomitant presence of breast cancer with one or more other types of cancer such as colon, vulva, lung, larynx, liver, uterus and kidneys has been presented in the literature. However, synchronous breast and renal cancer is very uncommon. Herein we present a woman with synchronous breast and renal cancer, and review the literature. A 77-year-old post-menopausal woman was admitted to our clinic complaining of left sided breast mass. On physical examination, there was a 3 cm palpable mass in the upper outer quadrant of the left breast along with a conglomerate of lymph nodes in the left axilla. Ultrasonography and mammography showed a 3 cm solid, hypoechoic mass in the upper outer quadrant and left axillary lymphadenopathy. The tru-cut biopsy of the lesion revealed invasive ductal carcinoma. The bone scintigraphy, thoracic and cranial computerized tomographies were normal. The abdominal computerized tomography identified a 3x3 cm solid renal mass with heterogeneous contrast enhancement in the posterior segment of the lower pole, which was suspicious for renal cell carcinoma. Breast conserving surgery and axillary lymph node dissection was performed, and the pathology specimen demonstrated invasive ductal carcinoma. The patient was discharged on postoperative day 5. Three weeks later partial nephrectomy was performed by urology department for the solid renal mass, and the pathology result showed clear cell-renal carcinoma with Fuhrman grade 3. The patient is being followed-up for renal carcinoma, and underwent radiotherapy for breast cancer. Hormonotherapy for breast cancer is still continuing. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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37. Memenin Nadir Görülen İntrakistik Karsinomu: İki Olgu Sunumu.
- Author
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İlhan, Enver, Üreyen, Orhan, Şenlikci, Abdullah, Yağcı, Ayşe, Yeldan, Eyüp, Salman, Tarık, and Tekeli, Mehmet Tahsin
- Subjects
- *
BREAST cancer , *BREAST cancer prognosis , *POSTMENOPAUSE , *ADJUVANT treatment of cancer - Abstract
Intracystic papillary carcinoma of the breast (IPC) is usually seen in postmenopausal elderly women. Its prognosis is much better than other type of breast tumors, and usually do not contain invasive components. Surgical excision with negative margins and axillary sentinel lymph node sampling is the recommended treatment. Two cases of intracystic papillary carcinoma of the breast that was treated at our clinic are herein presented. Both cases were postmenopausal, were both positive for estrogen and progesterone receptors and negative for HER 2. They underwent breast-conserving surgery. One patient had an invasive focus, therefore axillary lymph node sampling was performed, and the sentinel lymph node was not metastatic. This patient received hormonal therapy as well as radiotherapy. In the other case, there was no invasive focus and the surgical margins were negative, therefore, additional surgery was not performed. The patient is receiving hormonal therapy. Intracystic carcinoma of the breast should be kept in mind especially in elderly patients with breast cysts, with clinically or radiologically suspicious features, and biopsy and local excision should be considered. Although there is not any standard approach for patients with IPC, each patient must be evaluated for surgery and should be individually assessed in terms of adjuvant therapy [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
38. Factors Related to Multifocality in Papillary Thyroid Cancer: Analysis of 186 Cases
- Author
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ARSLAN, Enis, ÜREYEN, Orhan, EMİROĞLU, Mustafa, ÜNALP, Haluk Recai, TARCAN, Ercüment, and GÜNGÖR, Hilmi
- Subjects
Papillary thyroid cancer,multifocality,thyroid surgery ,Papiller tiroid kanseri,multifokalite,tiroid cerrahisi - Abstract
Objective: Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, and itaccounts for 70-80% of all malignancies of the thyroid gland. The aim of the present study wasto investigate the factors associated with multifocality in PTC.Materials and Methods: The medical records of the patients (patient charts, computerizedpatient registry), who underwent thyroidectomy in our clinics between May 2005 and July 2009and who were found to have PTC, were retrospectively reviewed for the factors affectingmultifocality.Results: A total of 186 cases (26 females [14%] and 160 males [86%]) were included in thestudy. The histopathological examination revealed a single nodule in 67 cases (36%) andmultiple nodules in 119 cases (64%). PTC was unifocal in 137 cases (73.6%) and multifocal in49 cases (26.4%). The tumor diameter was smaller than 1 cm in 103 patients (55.4%) and at orabove 1 cm in 83 patients (44.6%). The tumor diameter range was 0,5-4 cm (M:1,78, SD:1,1).Of 119 patients who were found to have multiple nodules, 49 (41.1%) were found to havemultifocality, and the remaining 67 patients with single nodule did not have any multifocality.There were no significant statistical analysis between age and gender about multifocality. Conclusion: The present study showed that tumor size, gender, nodule size, selected operationtype, capsule, and vascular invasion did not affect multifocality, and the presence of multiplenodules was the most single important factor affecting multifocality. Therefore, the authorssuggest that total thyroidectomy should be performed in patients with multinodular PTCdiagnosed preoperatively due to the possibility of multifocality, Amaç: Papiller tiroid kanseri (PTK) tiroid malignitelerinin en sık görülen tipidir ve tüm tiroidkanserlerinin %70-80’ini oluşturmaktadır. Çalışmamızın amacı PTK’nde multifokalite ile ilişkilifaktörleri araştırmaktır.Yöntem: Kliniğimizde Mayıs 2005 - Temmuz 2009 tarihleri arasında tiroidektomi yapılan vePTK saptanan olgular multifokaliteyi etkileyen faktörler yönünden olgu dosyası ve bilgisayarhasta kayıt sisteminde geriye dönük incelendi. Bulgular: Çalışma kriterlerimize uyan 26 kadın 160 erkek toplam 186 olgu dahil edildi.Patolojik incelemede 67 (%36) olguda tek nodül, 119 (%64) olguda multinodülarite bulundu.PTK 137 (%73.6) olguda unifokal, 49 (%26.4) olguda multifokal idi. Tümör çapı 103 (%55.4)olguda 1 cm’in altında, 83 (%44.6) olguda 1 cm ve üstü olarak bulundu. Tümör çaplarının 0,54 cm (ort:1.78, SD:1.1) arasında değiştiği görüldü. Multinodülarite saptanan 119 olgunun49’unda (%41.1) multifokalite bulunurken tek nodül olan 67 olgunun hiçbirisinde multifokalitebulunmadı (P:0.001) . Yaş grupları ve cinsiyet ile fokalite arasında istatistiksel olarak anlamlıfarklılık mevcut degildi (sırasıyla P:0.9, ve 0.44) .Sonuç: Çalışmamızda tümör boyutunun, cinsiyetin, nodül boyutunun, seçilen operasyon tipinin,kapsül ve vasküler invazyonun multifokaliteyi etkilemediğini; etkileyen en önemli ve tekfaktörün multinodülarite olduğu saptanmıştır. Bu yüzden preoperatif dönemde tanı koyulabilenmultinodüler PTK olgularında multifokalite olasılığı için total tiroidektomi yapılması gerektiğinidüşünmekteyiz
39. TİROİD NODÜLLERİNDE MALİGNİTE RİSKLERİ VE BU RİSKLERİN OPERASYON KARARINDAKİ ROLÜ NE OLMALIDIR?
- Author
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TEKELİ, Mehmet Tahsin, ÜSTÜNER, Mehmet Akif, DADALI, Emrah, GÖKÇELLİ, Uğur, GÜNGÖR, Hilmi, İLHAN, Enver, and ÜREYEN, Orhan
- Subjects
Thyroid nodule,thyroid cancer,thyroid neoplasia,risk factor ,Tiroid nodül,tiroid cancer,tiroid neoplazi,risk faktör - Abstract
Son yıllarda tiroid nodül saptanma oranı ve prevelansı yıldan yıla artmaktadır. Artan bu tiroid nodülü oranına sekonder olarak da nodül nedeniyle tiroid cerrahisi sayısı hızla artmaktadır. Bu çalışmada nodüler guatr nedeniyle tiroidektomi yapılan olguları analiz ederek hangi durumlarda cerrahi yapmamız gerektiğinin yanısıra gereksiz tiroidektomilerden nasıl kaçınabiliriz sorusunun yanıtını araştırdık. Kliniğimizde Haziran 2012 – Mayıs 2014 tarihleri arasında benign yada malign nedenlerle erişkin yaş grubunda nodüler guatr nedeniyle tiroidektomi operasyonu uygulanan olgular malignite ile ilişkili faktörler araştırılmak üzere retrospektif olarak kaydedildi Çalışmaya yaşları 23-84 arasında değişen 102 kadın 19 erkek olmak üzere toplam 121 olgu dahil edildi. Yaş, ultrasonografide US nodül sayısı ve major nodül çapları açısından gruplar arasında istatistiksel olarak anlamlı fark bulunmadı p>0,05 . Hormonal durum ve nodül yapıları açısından gruplar arasında istatistiksel olarak anlamlı fark bulundu p, In the recent years, the incidence and prevalence of thyroid nodules has gradually increased. Due to the increasing occurrence of thyroid nodules, the number of thyroid surgeries has rapidly increased as well. In this study, we analyzed cases that underwent thyroidectomy due to nodular goiter in order to identify the conditions/cases in which surgery became necessary. We thus aimed to determine how unnecessary thyroidectomies can be avoided
40. PEPTİK ÜLSER PERFORASYONLARINDA MORBİDİTE VE MORTALİTEYE ETKİ EDEN FAKTÖRLER
- Author
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FAKTÖRLER, Etki Eden, ÜSTÜNER, Mehmet Akif, İLHAN, Enver, ŞENLİKÇİ, Abdullah, DADALI, Emrah, GÖKÇELLİ, Uğur, and ÜREYEN, Orhan
- Subjects
Peptik ülser perforasyonu,morbidite,peptik ülser hastalığı ,Peptic ulcus perforation,morbidity,peptic ulcus disease - Abstract
Günümüzde H2-reseptör blokerleri ve proton pompa inhibitörlerinin kullanımı sonucu peptik ülser hastalığında elektif cerrahi gereksinimi azalmıştır. Ancak komplikasyonlara bağlı acil cerrahi sıklığında herhangi bir değişiklik olmamıştır. Perforasyon meydana gelen hastalarda morbidite ve mortalite halen büyük bir problemdir. İzmir Bozyaka Eğitim ve Araştırma Hastanesi Genel Cerrahi Kliniği’nde 2008-2013 yılları arasında peptik ülser perforasyonu nedeniyle ameliyat edilen hastaların dosya ve elektronik kayıtları retrospektif olarak incelendi. Toplam 50 hastanın 41 %82 'i erkek 9 %18 'u kadındı. Yaş ortalaması 48.9 idi. Ortalama hastanede kalış süresi 7.8 gündü. Peptik ülser perforasyonu en sık yaz mevsimi %32 ve Ağustos ayında %12 görüldü. Kasım ayında 5yıl boyunca perforasyon görülmedi.Perforasyon en sık, 31 %62 hastada olmak üzere duodenumda görüldü. Bunu 17 %34 hasta ile jukstapilorik ve 2 %4 hasta ile anastomoz hattı perforasyonları izledi. İki hasta tekrarlayan perforasyon nedeniyle ameliyat edildi. Tüm hastalara antibiyotik tedavisi yapıldı. Perforasyon deliği çapı 39 %78 hastada 1cm altı,7 %14 hastada 1-2 cm arası, 4 %8 hastada 2 cm ve üstü olarak bulundu. Ameliyat öncesi, 38 %72 hastada lökositoz, dokuz %18 hastada kreatin yüksekliği ve 11 %22 hastada amilaz yüksekliği tespit edildi. Ameliyat sonrası üç hastada yara yeri infeksiyonu, iki hastada pnömoni, bir hastada deliriyum tablosu, dört hastada akut böbrek yetmezliği, bir hastada sepsis ve bir hastada evisserasyon gelişti. Toplam 4 %8 hasta eks oldu. Morbidite ve mortalite gelişen hastaların çoğu ileri yaş grubunda olup yandaş hastalıklara sahiptiler. Yandaş hastalığa sahip, ileri yaş ve gecikmiş perforasyonu olan hastalarda morbidite ve mortalite oranı artmaktadır. Ameliyat öncesi lökositoz, yüksek amilaz değeri ve kreatin yüksekliği preoperatif dönemde morbidite ve mortalitenin tahmininde kullanılabilinir, Today, as a result of the use of H2-receptor blockers and proton pump inhibitors in peptic ulcer disease has decreased the need for elective surgery. However, there is no change in the frequency emergency surgery due to complications. Morbidity and mortality in patients with perforation occurring is still a major problem. We reviewed retrospectively the patients who underwent surgery for peptic ulcer perforation with files and computer records between 2008- 2013 in İzmir Bozyaka Training and Research Hospital General Surgery Department. Total of 50 patients, 41 82% were male and 9 18% were women. The mean age was 48.9 years. Average hospital stay was 7.8 days. Peptic ulcer perforations were seen most common in summer season and August. There was no perforation for 5 years in November. Perforations were seen most common in duodenum in 31 62% patients. That followed by the perforations of juxtapyloric in 17 34% patients and anastomosis in 2 4% patients. Two patients were operated due to recurrent perforation. All patients were treated with antibiotics. Perforation hole diameter were found in 39 78% patients below 1 cm, in 7 14% patients between 1-2 cm and 4 8% patients 2 cm and above. There was leukocytosis in 38 72% patients, increased creatinine in 9 18% patients and increased amylase in 11 22% patients. There was wound infection in three patients, pneumonia in two patients, delirium in one patient, acute renal failure in four patients, sepsis in one patient, evisceration in one patient after surgery. Total 4 8% patients had died. Most of the patients with morbidity and mortality in the elderly group had concomitant diseases. Morbidity and mortality is increasing in patients with co-morbid disease, advanced age and delayed perforation. Preoperative leukocytosis, increased amylase and increased creatinine can be used to predict morbidity and mortality
41. How Should Be the Approach to the Breast Mass According to the Radiological BI-RADS Classification? A Comparison with Histopathological Results
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İLHAN, Enver, ADIBELLİ, Zehra Hilal, ÜSTÜNER, Mehmet Akif, ŞENLİKÇİ, Abdullah, DADALI, Emrah, GÖKÇELLİ, Uğur, YAĞCI, Ayşe, GÜNGÖR, Hilmi, and ÜREYEN, Orhan
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BI-RADS,meme kanseri,histopatoloji ,BI-RADS,breast cancer,histopathology - Abstract
Purpose: BI-RADS 3 and 4 constitute the most debated group of the BI-RADS classificationused in the evaluation of breast masses. The aim of the present study was to compare radiologicaland histopathological results of the patients who were radiological determined as BI-RADS 3,4 or 5, and who underwent biopsy, and to review proper approach to such lesions.Methods: The medical charts of the patients who were found to have a breast mass on physicalexamination and/or using radiological investigation between January 2011 and August 2013,and who were classified as BI-RADS 3, 4 or 5 using ultrasonography, mammography, and/ormagnetic resonance imaging, and who subsequently underwent biopsy examination wereretrospectively reviewed.Results: A total of 97 patients were included in the study. Of the cases in BI-RADS 3 group,11% had malignant lesion, 58.8% of the patients in the BI-RADS 4 group had malignant lesion,and all patients in the BI-RADS 5 group had malignant lesion. When the patients in BI-RADS4 were divided into subgroups, the rate of malignant was 23% in the 4A group and 88% in the4C group. Conclusion: The lesions in BI-RADS 3 group often have benign character, but it must beremembered that they may be rarely malignant lesions. In BI-RADS 4 group, the lesions in 4Ahave low malignancy potential and the lesions in 4C group have extremely high malignancypotential, Amaç: Memedeki kitlelerin değerlendirilmesinde kullanılan BI-RADS sınıflamasının en çoktartışılan grubunu BI-RADS 3 ve 4 oluşturmaktadır. Bu çalışmada, radyolojik olarak BI-RADS3, 4 ve 5 grubunda değerlendirilen ve biyopsi yapılan hastaların radyolojik ve histopatolojiksonuçlarını karşılaştırmanın yanı sıra bu kitlelere uygun yaklaşımı tekrar gözden geçirmeyiamaçladık.Yöntem: Ocak 2011 ile Ağustos 2013 tarihleri arasında memede fizik muayene ve/veyaradyolojik olarak kitle saptanan; ultrasonografi, mamografi yada manyetik rezonansgörüntülemeden biri yada birkaçı yapılan hastalardan radyolojik olarak BI-RADS 3, 4 yada 5olan ve biyopsi yapılan hastaların dosyaları retrospektif olarak incelendi.Bulgular: Toplam 97 olgu çalışmaya dahil edildi. BI-RADS 3 kategorideki olguların %11’imalign, BI-RADS 4’ün %58.8’i malign iken BI-RADS 5 lezyonların hepsi maligndi. BI-RADS4 alt gruplarına ayrıldığında 4A’ da malignite oranı %23 iken 4C de %88 idi. Sonuç: BI-RADS 3 lezyonlar genellikle benign karekterdedir, nadiren de olsa bunların malignolabileceği akılda tutulmalıdır. BI-RADS 4 kategorideki lezyonlarda 4A’da malignite potansiyelidüşük, 4C’de ise oldukça yüksektir
42. 60 YAŞ ÜSTÜ APENDEKTOMİ YAPILAN OLGULARIN RETROSPEKTİF ANALİZİ
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ŞENLİKCİ, Abdullah, ÜSTÜNER, Mehmet Akif, DADALI, Emrah, GÖKÇELLİ, Uğur, ÜREYEN, Orhan, and İLHAN, Enver
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Akut Apandisit,ileri yaş,akut karın,morbidite,mortalite ,Acute appendicitis,elderly,acute abdominal pain,morbidity,mortality - Abstract
Akut apandisit en sık gözlenen acil cerrahi hastalıktır. Daha çok gençlerde görülür. Çalışmamızda apendektomi yapılan 60 yaş üstü hastaları sunduk. Akut apandisit öntanısı ile Kasım 2011-Mart 2013 tarihleri arasında apendektomi yapılan 60 yaş üstü hastaların dosya ve bilgisayar kayıtları retrospektif olarak değerlendirildi.Ameliyat öncesi Alvarado skorları, US ve BT bulguları, morbidite, mortalite ve histopatoloji sonuçları incelendi. Toplam 172 hastaya akut apandisit öntanısı ile apendektomi yapıldı. Bu hastaların 60 yaş ve üzeri olan 13 %7.5 'ü çalışmaya dahil edildi. Hastaların 9 %59.3 'u erkek, 4 %30.7 'ü kadın idi. Yaş ortalaması 67.1 idi. Alvarado skoru 8 %61.5 hastada 7 ve üzerinde, 5 %38.5 hastada 4-7 arasında idi.Ameliyat öncesi 11 hastaya US, 7 hastaya BT yapıldı.Ameliyat sonrasında 1 %7.7 hastada akut böbrek yetmezliği, 1 %7.7 hastada yüzeyel yara yeri enfeksiyonu gözlendi. Mortalite görülmedi. Histopatolojik incelemede 6 %46.1 hasta akut apandisit, 2 %15.3 hasta perfore apandisit, 2 %15.3 hasta flegmonöz apandisit, 1 %7.7 hasta divertikülit perforasyonu, 2 %15.3 hasta ise normal appendiks bulguları olarak değerlendirildi. Negatif laparotomi oranı %15.3 idi. US, pozitif laparotomi yapılan tüm hastalara yapılmıştı. Bunlardan 4 %36.3 ’ünde ultrasonografi bulguları akut apandisit ile uyumlu, kalan7 %63.7 ’sinde uyumlu değildi. BT ise, pozitif laparotomi yapılan hastalardan yedisine yapılmıştı. Bunlardan 5 %71.4 'inde BT bulguları akut apandisit ile uyumlu, 2’sinde %28.6 uyumlu değildi. Negatif laparotomi yapılan 2 hastadan birinin hem USG hemde BT bulguları normal, diğerinde ise akut apandisit ile uyumlu idi. Akut apandisit daha çok genç yaş grubunda görülür. 60 yaş üzerinde daha nadir görülmesi, tanı koymadaki güçlük ve ameliyat sonrasındaki komplikasyonların daha fazla görülmesi nedeniyle tanı koyma sürecinde daha dikkatli olunmalıdır, Acute appendicitis is the most common emergency surgical disease. It is commonly seen in young patients. In this study we present cases who were performed appendectomy over 60 years old. We reviewed retrospectively the patients who were performed appendectomy with the diagnosis of acute appendicitis over 60 years old with files and computer records between November 2011-March 2013 in Izmir Bozyaka Education and Research Hospital, Surgery Clinic. Alvarado score, USG and CT findings, morbidity, mortality, and histopathology reports were analyzed Appendectomy was performed with the diagnosis of acute appendicitis in total of 172 patients. 13 7.5% of these patients who was 60 years of age and above were included in the study. 9 59.3% patients were male and 4 30.7% of them were female. The mean age was 67.1 years. Alvarado score was in 8 61,5% patients 7 and above and in 5 38,5% was between 4-7. In preoperative period US was performed to 11 patients and CT was performed to 7 patients. There was acute renal failure in 1 7,7% patient and there was superficial wound infection in 1 7,7% patient postoperatively. There was no mortality. In histopathological examination there were acute appendicitis in 6 46,1% patients, perforated appendicitis in 2 15,3% patients, phlegmoneus appendicitis in 2 15,3% patients, diverticulitis perforation in 1 7,7% patient, normal appendix findings in 2 15,3% patients. The negative laparotomy rate was 15.3%. US was made to all patients who were performed pozitive laparotomy. In 4 patients 36,3% US findings was compatible with acute appendicitis and in 7 patients 63,7% US findings wasn't compatible with acute appendicitis. CT was performed to 7 patients who were performed positive laparotomy. In 5 71,4% patients CT findings was compatible with acute appendicitis and in 2 28,6% patients CT findings wasn't compatible with acute appendicitis. In 1 of 2 patient who were performed negative laparotomy USG and CT findings were normal and in the other patient USG and CT findings was compatible with acute appendicitis. Conclusion: Acute appendicitis is commanly seen in young patients. Because of they seen rarely over 60 years old, difficulty in diagnosis and postoperative complications are more frequent we should be more careful in the process of diagnosis
43. ŞARAPNEL´E BAĞLI ANA SAFRA YOLU YARALANMASI; OLGU SUNUMU
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İFLAZOĞLU, Nidal, GÖKÇE, Numan Oruç, and ÜREYEN, Orhan
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Bile duct injury,gunshot wound,hepatic pedicle injury ,Safra yolu yaralanması,ateşli silah yaralanması,hepatik pedikül yaralanması - Abstract
Travmatik ekstrahepatik safra yolu yaralanmaları nadir görülüp, tedavileri zor ve tartışmalıdır. Safra yolu yaralanmalarının yönetiminin zorlukları ve eşlik eden yaralanmalar nedeniyle morbidite ve mortalite yüksek olabilmektedir. Şarapnel parçası nedeniyle hepatik kanal bifurkasyon yaralanması olan sağ ve sol kanal komplet ayrışması , vena porta yaralanmasının eşlik ettiği, 55 yaşında erkek olgunun tedavi yönetimini sunuyoruz, Extrahepatic bile duct traumatic injuries are extremely rare and their treatment is difficult and with several controversies. Owing to complexity of bile duct injury management and concomitant injuries, mortality and morbidity could be in highrates. We report a 55 years old man with hepatic duct bifurcation injury complete transection of right and left duct and vena porta injury caused from shrapnel injury and it's management
44. MORTALİTESİ HALEN YÜKSEK OLAN AKUT BATIN NEDENİ; AKUT MEZENTER İSKEMİ
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ŞENLİKCİ, Abdullah, İLHAN, Enver, ÜSTÜNER, Mehmet Akif, and ÜREYEN, Orhan
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Akut mezenterik iskemi,mortalite,Acil karın ,Acute mesenteric ischemia,mortality,acute abdomen - Abstract
Akut mezenter iskemi AMİ , erken tanı ve tedavi gerektiren hayatı tehdit edici bir akut karın hastalığıdır. Biz burada AMİ tanısıyla opere edilen olgulardaki morbidite ve mortaliteye etkili faktörleri incelemeyi amaçladık AMİ özellikle kardiyo vasküler hastalığa sahip karın ağrılı hastalarda ayırıcı tanıda mutlaka düşünülmeli ve erken girişim yapılmalıdır, Acute mesenteric ischemia is a life-threatening acute abdominal disease which needs early diagnosis and treatment. Remains associated with high morbidity and mortality rates. Consider the possibility of its clinical and on time reaction can be life saving
45. NODÜLER GUATR TANISI İLE AMELİYAT EDİLEN VAKALARDA MALİGNİTE SIKLIĞI
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ŞARLAR, Hakan, İLHAN, Enver, ÜSTÜNER, Mehmet Akif, ŞENLİKCİ, Abdullah, and ÜREYEN, Orhan
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Thyroid nodule,thyroid carcinoma,fine needle aspiration biopsy ,Tiroid nodülü,tiroid kanseri,ince iğne aspirasyon biopsisi - Abstract
Bu çalışmada tiroid nodülü nedeniyle ameliyat edilen hastalarda demografik, laboratuar, görüntüleme ve sitoloji bulgularının histopatoloji sonuçlarıyla ilişkisi araştırıldı. Nodüler guatr tanısıyla ameliyat edilen olgular yaş, cinsiyet, nodül sayısı, nodül boyutu, fonksiyon durumu, hormon profili, ameliyat tipi, sitoloji ve histopatoloji sonuçlarına göre retrospektif olarak değerlendirildi. Toplam 179 olgunun 147 %82.1 ’si kadın, 32 %17.9 ’si erkek idi. Ortalama yaş 51.3 aralık 22- 81 idi. Olguların çoğunluğu %69.3 30-60 yaş grubundaydı. Multinodüler guatr 142 %79.3 , soliter nodül 37 %20.7 olguda mevcuttu. Toplam 41 hastaya İİAB yapıldı. Bunlardan 19 %46.3 ’u yetersiz materyal olarak değerlendirildi. Geri kalan 22 %53.7 olgunun 15’i benign, beşi şüpheli malign ve ikisi malign tanısı aldı. Histopatolojik olarak malignite saptanan 27 %15.09 olgunun; 15 %55.6 ‘inde papiller karsinom, 3 %11.1 ’ünde papiller mikrokarsinom, 6 22.2 ’sında folliküler karsinom, 3 %11.1 ’ünde Hurthle hücreli karsinom tesbit edildi. Bunların 21 %77.8 ’i multinodüler, 6 %22.2 ’sı soliter nodülü olan hastalardı. Histopatoloji sonuçları ile yaş p =0.601 , cinsiyet p =0.790 ,nodül sayısı p=0.829 , nodül boyutu p=0.845 , tiroid fonksiyon durumu 0.744 , hormon profili p=0.206 , sitoloji p=0.227 ve ameliyat tipi p=0.350 arasında istatistiksel olarak anlamlı ilişki tesbit edilmedi. Tiroid nodülü tesbit edilen hastalarda ameliyat gereksinimini azaltmak ve tiroidektominin istenmeyen etkilerinden kaçınmak için cerrah, radyolog ve patolog işbirliği ile sitolojik tetkik uygulama ve değerlendirmede başarı ve beceriyi geliştirmek için gerekli çaba sarfedilmelidir., In this study, we examined the relationship between demographic, laboratory, imaging and cytology results with histopathology results in patients who underwent surgery for thyroid nodules. Patients who underwent surgery for nodular goiter were evaluated retrospectively according to age, gender, number of nodules, nodule size, functional status, hormones, surgery type, cytology and the results of histopathology. A total of 179 patients, 147 82.1% were female and 32 17.9% were male. Mean age was 51.3 range 22-81 years. The majority of patients 69.3% were between 30-60 years of age. There was multinodular goiter in 142 79.3% cases and solitary nodules in 37 20.7% cases. FNAB was performed in 41 patients. 19 46.3% of these patients were evaluated as non diagnostic material. The remaining 22 53.7% were diagnosed 15 cases were benign, five cases were suspected malignant and two caes were malignant. Histopathological examination of 27 patients with diagnosed malignancy, papillary carcinoma, papillary microcarcinoma, follicular carcinoma and Hurthle cell carcinoma were detected in 15 55.6% , 3 11.1% , 6 22.2 and 3 11.1% cases respectively. 21 77.8% of the patients had multinodular goitre and 6 22.2% patients had solitary nodules. There was not found to be statistically significant relationship between the results of histopathology with age p = 0.601 , gender p = 0.790 , number of nodules p = 0829 , nodule size p = 0845 , thyroid function status 0744 , hormonal profile p = 0.206 , cytology p = 0227 and type of surgery p = 0.350 . Surgeons, radiologists, and pathologists should be made to develop the skill in collaboration with cytological examination and evaluation of implementation success and efforts for reducing the need for surgery in patients with thyroid nodules identified and avoiding undesirable effects of thyroidectomy.
46. TİROİD PAPİLLER KANSERİNDE MULTİFOKAÜTE İLE İLİŞKİLİ FAKTÖRLER: 186 OLGUNUN ANALİZİ.
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Güngör, Hilmi, Arslan, Enis, Üreyen, Orhan, Emiroğlu, Mustafa, Ünalp, Haluk Recai, and Tarcan, Ercüment
- Abstract
Objective: Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, and it accounts for 70-80% of all malignancies of the thyroid gland. The aim of the present study was to investigate the factors associated with multifocality in PTC. Materials and Methods: The medical records of the patients (patient charts, computerized patient registry), who underwent thyroidectomy in our clinics between May 2005 and July 2009 and who were found to have PTC, were retrospectively reviewed for the factors affecting multifocality. Results: A total of 186 cases (26 females [14%] and 160 males [86%]) were included in the study. The histopathological examination revealed a single nodule in 67 cases (36%) and multiple nodules in 119 cases (64%). PTC was unifocal in 137 cases (73.6%) and multifocal in 49 cases (26.4%). The tumor diameter was smaller than 1 cm in 103 patients (55.4%) and at or above 1 cm in 83 patients (44.6%). The tumor diameter range was 0,5-4 cm (M:1,78, SD:1,1). Of 119 patients who were found to have multiple nodules, 49 (41.1%) were found to have multifocality, and the remaining 67 patients with single nodule did not have any multifocality. There were no significant statistical analysis between age and gender about multifocality. Conclusion: The present study showed that tumor size, gender, nodule size, selected operation type, capsule, and vascular invasion did not affect multifocality, and the presence of multiple nodules was the most single important factor affecting multifocality. Therefore, the authors suggest that total thyroidectomy should be performed in patients with multinodular PTC diagnosed preoperatively due to the possibility of multifocality. [ABSTRACT FROM AUTHOR]
- Published
- 2014
47. Usefulness of FGSI and UFGSI scoring systems for predicting mortality in patients with Fournier's gangrene: A multicenter study.
- Author
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Üreyen O, Acar A, Gökçelli U, Atahan MK, and İlhan E
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- Adult, Cohort Studies, Humans, Middle Aged, Prognosis, Sensitivity and Specificity, Severity of Illness Index, Fournier Gangrene diagnosis, Fournier Gangrene epidemiology, Fournier Gangrene mortality
- Abstract
Background: This study aimed to evaluate the usefulness of Fournier's gangrene scoring index (FGSI) and Uludag FGSI (UFGSI) for predicting mortality in patients with FG., Methods: Patients who underwent treatment and follow-up in the A division department of general surgery at two education and research hospitals between January 2012 and December 2015 were evaluated for mortality-related factors. The sensitivities of FGSI and UFGSI scoring systems for predicting mortality-related factors and disease prognosis were evaluated. Patients were grouped as survivors (Group I) or non-survivors (Group II)., Results: In total, 29 patients were included in the study. The mean age (±SD) was 51.52±13.36 years. The mortality rate was 20.6% (six patients). Bacterial growth was observed in wound cultures of 17 patients (58.6%). Of the patients with bacterial growth, 11 (47.8%) were in Group I and six (100%) were in Group II. The presence of bacterial growth was significantly associated with mortality (p=0.028). Fourteen patients (48.3%) had comorbid conditions. The number of comorbid conditions was related (p=0.049). FGSI and UFGSI scores were significantly higher in Group II than in Group I (p=0.002 and p=0.001, respectively). Among UFGSI parameters, extent of disease, body temperature, pulse rate, and HCO3 values were significantly higher in Group II than in Group I (p<0.05). The FGSI and UFGSI scoring systems had 100% sensitivity and 78.2% and 73.9% specificity, respectively, for predicting mortality., Conclusion: The FGSI and UFGSI scoring systems are valuable for predicting mortality in patients with FG. The extent of the disease was an important prognostic parameter in this study. Whichever scoring system is used, we suggest the use of the extent of disease score in UFGSI.
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- 2017
- Full Text
- View/download PDF
48. Extra-adrenal myelolipoma with hemolytic anemia.
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İflazoğlu N, Üreyen O, and Keleş M
- Abstract
Myelolipomas are rare benign tumors often detected as adrenal masses. Extra-adrenal myelolipomas are encountered even more rarely. The rate of detection of these lesions is increasing with improved radiological techniques. Because of their localization and morphological similarities to well differentiated liposarcomas, extra-adrenal myelolipomas need to be differentiated from other aggressive neoplasms. Preoperative imaging and percutaneous biopsy are important tools in the diagnosis of these lesions. We report a very rare case of an extra-adrenal perirenal myelolipoma associated with hemolytic anemia. The etiology, differential diagnosis, and treatment options for the lesion have been discussed. Fat-containing tumors of the retroperitoneum should be considered in the differential diagnosis. Accurate diagnosis is important to avoid over-treatment of these benign lesions., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors.
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- 2015
- Full Text
- View/download PDF
49. Intracystic Carcinoma of the Breast: Report of Two Cases.
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İlhan E, Üreyen O, Şenlikci A, Yağcı A, Yeldan E, Salman T, and Tekeli MT
- Abstract
Intracystic papillary carcinoma of the breast (IPC) is usually seen in postmenopausal elderly women. Its prognosis is much better than other type of breast tumors, and usually do not contain invasive components. Surgical excision with negative margins and axillary sentinel lymph node sampling is the recommended treatment. Two cases of intracystic papillary carcinoma of the breast that was treated at our clinic are herein presented. Both cases were postmenopausal, were both positive for estrogen and progesterone receptors and negative for HER 2. They underwent breast-conserving surgery. One patient had an invasive focus, therefore axillary lymph node sampling was performed, and the sentinel lymph node was not metastatic. This patient received hormonal therapy as well as radiotherapy. In the other case, there was no invasive focus and the surgical margins were negative, therefore, additional surgery was not performed. The patient is receiving hormonal therapy. Intracystic carcinoma of the breast should be kept in mind especially in elderly patients with breast cysts, with clinically or radiologically suspicious features, and biopsy and local excision should be considered. Although there is not any standard approach for patients with IPC, each patient must be evaluated for surgery and should be individually assessed in terms of adjuvant therapy., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors.
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- 2015
- Full Text
- View/download PDF
50. Diagnostic difficulty in subepithelial gastric tumors, and the efficacy of laparoscopy-assisted distal gastrectomy in gastric cancer.
- Author
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İlhan E, Alemdar A, and Üreyen O
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- Female, Humans, Carcinoma, Signet Ring Cell, Stomach Neoplasms
- Published
- 2015
- Full Text
- View/download PDF
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