1. CONTEMPORARY APPROACH TO THE TREATMENT OF GLIOMA IN NEUROSURGICAL CLINIC OF CLINICAL HOSPITAL CENTER OF RIJEKA
- Author
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Ćefo, Aldo, Ledić, Darko, Girotto, Dean, Houra, Karlo, and Perković, Olivio
- Subjects
Gliom ,Treatment ,KBC Rijeka ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Kirurgija ,Clinical Hospital Center of Rijeka ,Glioma ,Glioblastom ,Liječenje ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Surgery ,GBM - Abstract
Cilj: Cilj je bio analizirati terapijski pristup pacijentima oboljelima od glioma na Klinici za neurokirurgiju KBC-a Rijeka te usporediti dobivene podatke sa današnjim standardima na tom području. Materijali i metode: Retrospektivno je pretražena i analizirana medicinska dokumentacija pohranjena na BIS-u. U analizu su uvrštena 124 pacijenta dobi od 10 mjeseci do 84 godine koji su liječeni na Klinici za neurokirurgiju KBC-a Rijeka u periodu od 01. siječnja 2014. do 15. ožujka 2020. godine. Iz dobivenih podataka izvedene su distribucija po dobi, spolu, dijagnozi, vrsti primijenjene terapije te postotak reoperacija. Rezultati: Utvrđeno je da je među dijagnosticiranim gliomima najučestalija dijagnoza bio GBM sa udjelom od 68%, dok su preostalih 32% činili gliomi nižeg stupnja malignosti, i to 14% astrocitomi, 10% oligodendrogliomi te 8% ependimomi. Pacijenti oboljeli od GBM najčešće su bili liječeni kombinacijom maksimalne kirurške resekcije i adjuvantne kemoradioterapije. Postotak reoperacija kod tih pacijenata je bio 11%. Zaključak: Pacijentima oboljelima od neke vrste glioma koji se liječe u KBC-u Rijeka osiguran je terapijski pristup koji je u skladu sa današnjim svjetskim standardima. Ovo je prva analiza na ovu temu provedena na Klinici za neurokirurgiju KBC-a Rijeka. Kao takva, mogla bi biti korisna za usporedbu sa budućim istraživanjima novijih terapijskih pristupa ovim pacijentima., Aim: The aim of this study was to analyze the approach to the patients suffering from some subtype of glioma in Neurosurgical clinic of Clinical Hospital Center of Rijeka and to compare the findings with the literature. Patients and methods: This study was a retrospective analysis of medical documentation stored on BIS (Hospital Informational System). The analysis covered one hundred twenty-four patients aged between ten months and eighty-four years, who were treated at the Neurosurgical clinic of the Clinical Hospital Center of Rijeka in the period between January 1st,2014. and March 15th,2020. Gender, age, diagnosis and therapy approach distribution along with the percentage of reoperations were conducted from the obtained data. Results: It was found that the most common diagnosis among all of the glioma diagnoses, was GBM with the share of 68% and the remaining 32% were lower malignancy gliomas, including astrocytoma (14%), oligodendroglioma (10%) and ependymoma (8%). Patients suffering from GBM were most commonly treated with the combination of surgical resection and adjuvant chemotherapy. The reoperation percentage in those patients was 11%. Conclusion: Patients treated at the Clinical Hospital Center of Rijeka suffering from some type of glioma are offered the therapeutic approach which is consistent with today's world standards. As the first analysis of this topic at the Neurosurgical clinic of the Clinical Hospital Center of Rijeka, it could be useful for comparison with the future studies of newer therapeutic approaches to these patients.
- Published
- 2020