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In patients with schizophrenia, a chronic psychiatric disorder, cognitive impairments have a significant impact on functioning as well as symptoms. Cognitive remediation (cognitive remediation) interventions are a treatment approach that aims to improve cognitive functioning in patients with schizophrenia. These interventions can be categorized as "bottom-up" approaches that directly target cognitive functions and "top-down" approaches that indirectly affect cognitive functions. In this study, the contribution of bottom-up cognitive remediation interventions to functioning in schizophrenia was examined. The study provides evidence that bottom-up cognitive remediation interventions can improve cognitive functioning, social functioning and quality of life in patients with schizophrenia. When the literature is reviewed, it is observed that there is no research or programs about bottom-up cognitive remediation interventions in Türkiye. It is recommended that programs for bottomup cognitive remediation interventions should be developed and utilized in Türkiye and they should be incorporated with the current therapy and rehabilitation approaches. It is important to benefit from technological opportunities, to increase the duration and intensity of interventions, to consider the issue of motivation and to ensure the integration of interventions into daily life, in creation of future bottom-up cognitive remediation intervention programs, in order to increase effectiveness, sustainability and cost-efficiency. [ABSTRACT FROM AUTHOR]

Objective: The collection of methods that enable combining the findings of several independent studies on the topic of interest with appropriate statistical methods is called meta-analysis. Schizophrenia is a complex psychiatric disease linked to many environmental and genetic factors and affects up to 1% of the world's population. A candidate gene for schizophrenia susceptibility is the catechol-O-methyltransferase (COMT) gene. This study aimed to combine the odds ratios obtained from different studies according to the rs737865 SNP (single nucleotide polymorphism) of the COMT gene for schizophrenia by meta-analysis. Material and Method: Publications written in English were scanned with the keywords "COMT and schizophrenia" in Web of Science, Pubmed, and Google Scholar databases until October 2024. Common odds ratio estimates were obtained with the help of appropriate meta-analytic methods under different genetic models for 17 studies that met the inclusion criteria, as well as 8 and 4 studies for Asians and Caucasians, respectively, by race. STATA 14 program was used for all analyses. Results: Under different genetic models applied to seventeen studies, only carriers of the CC genotype were found to have a higher risk for schizophrenia than carriers of the T (TT+CT) allele [OR=1.133 (95% CI=1.008 - 1.273)]. In subgroup analyses according to race, no risk was found for Asians. In contrast, for Caucasians, it was found that carriers of the C (CC+CT) allele had an increased risk of schizophrenia compared to those with TT genotype [OR=1.586 (95% CI=1.349 - 1.865)]. Conclusion: With the help of applied meta-analytic methods, overall estimates were obtained for odds ratios (OR) obtained from independent studies under different genetic models. However, it is thought that the association between COMT gene rs737865 SNP and schizophrenia should be examined with studies conducted in larger groups homogeneous in terms of ethnicity. [ABSTRACT FROM AUTHOR]

Background/Aims: There remains a need to investigate alternative pathophysiological processes in schizophrenia such as neuroinflammatory processes. We aimed to compare blood count levels, with a particular focus on peripheral blood inflammatory cell levels, among three distinct groups of participants: schizophrenia patients taking clozapine, schizophrenia patients taking antipsychotics other than clozapine, and healthy controls. We also evaluated the relationship between these findings and clinical characteristics. Methods: The SC group included 47, the SA group included 61 patients and the HC group included 65 healthy controls. The neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and monocyte-lymphocyte ratio (MLR) were calculated by dividing the respective cell counts from white blood cell count (WBC). The relationship between these measures and clinical characteristics are done with the Positive and Negative Syndrome Scale (PANSS). Results: WBC counts were significantly higher in the SC group than in the SA and HC groups. The log transformed NLR (LnNLR) was significantly higher in the SC group than the HC group and SA group, but there were no difference between the the SA and HC groups. LnNLR was significantly correlated with PANSS positive, general and total scores, but not significantly correlated with PANNS negative score. LnNLR was significantly different between groups after adjusting for age and gender using ANCOVA. Conclusions: The current study sheds light on the potential immunological alterations associated with schizophrenia and its treatment with clozapine. The elevated NLR in individuals receiving clozapine treatment underscores the need for further research to elucidate the underlying mechanisms and clinical implications of this observation. [ABSTRACT FROM AUTHOR]

Background/Aims: The relationship between vitamin D and schizophrenia has been the focus of studies in the last 20 years. Studies have shown that approximately 65% of schizophrenia patients have vitamin D deficiency. This study aimed to retrospectively investigate the vitamin D levels of schizophrenia and schizoaffective disorder (SAD) patients receiving inpatient treatment at a tertiary care hospital. Material and Methods: Patients diagnosed with Schizophrenia and SAD who received inpatient treatment at the psychosis service of a tertiary care hospital in the last two years (2021-2023) were included in this study. The data of 230 patients were examined retrospectively from hospital and file records. Results: Among the patients in the study, 47.8% were female with a mean age of 42.3±15.8 years, and 52.2% were male with a mean age of 37.2±14.1 years. Among women, 24.5% had SAD and 75.5% had schizophrenia, among men, 30.8% had SAD and 69.2% had schizophrenia. Vitamin D deficiency was found in 73% of the group, vitamin D insufficiency was found in 17.4%, and normal vitamin D levels were found in 9.6%. No statistically significant relationship was found when vitamin D levels were compared between male and female patient groups (p = 0.068). When vitamin D levels were compared between patient groups diagnosed with schizophrenia and SAD, no statistically significant relationship was found. (p>0.05) Conclusion: Despite advances in the treatment of schizophrenia, these advances are insufficient to reduce the morbidity and mortality of the disease, so prophylactic measures should be explored. Adequate D vitamin supplementation during critical stages of life, including pregnancy, might be a meaningful, simple, safe, and cost-effective intervention. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Psychiatry is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Academic Research in Nursing (JAREN) is the property of Hemsirelikte Egitim ve Arastirma Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Amaç: Bu araştırmada, şizofrenili bireylerde Bireyselleştirilmiş İçgörü Eğitimi’nin (BİE), bireylerin içgörü düzeyi, aktivite performansı ve aktivitelerden duydukları memnuniyet düzeyine etkisinin incelenmesi amaçlandı.Yöntemler: Çalışma, psikiyatri hekimi tarafından şizofreni tanısı almış 6 birey ile gerçekleştirildi. Tüm bireylere Bireyselleştirilmiş İçgörü Eğitimi (BİE) haftada 1 kez toplamda 16 seans boyunca uygulandı. Bireylere (3’ü kadın 3’ü erkek) eğitim öncesi ve sonrasında Sosyodemografik Bilgi Formu, Kanada Aktivite Performans Ölçeği (KAPÖ) ve İçgörünün Üç Bileşenini Değerlendirme Ölçeği (İÜBDÖ) uygulandı. Veriler gruplar arası değerlendirme yöntemlerinden Wilcoxon testi ile analiz edildi.Bulgular: BİE sonucunda şizofrenili bireylerin içgörü düzeyinde (p=,027), aktivitelerdeki performans düzeyinde (p=,026; p=,027; p=,039) ve aktivitelerden duyulan memnuniyet düzeyinde (p=,026; p=,027; p=,042) istatistiksel olarak anlamlı bir değişikliğin olduğu görüldü. Ayrıca, BİE ile içgörü düzeyleri, aktivite performansları ve aktivitelerden duydukları memnuniyet düzeyleri önemli derecede iyileşti.Sonuç: Bu araştırma, şizofrenili bireylerde içgörü gelişiminin, bireylerin günlük yaşam aktivitelerindeki performans ve bu performanstan duyulan memnuniyet seviyesinde artış oluşturabileceğine dair ön kanıtlar sunmaktadır. Ayrıca BİE’nin, klinik uygulamalarda profesyoneller için, uygulanabilir yöntemlerden biri olabileceğini düşünmekteyiz.

Objective: One of the serious mental disorders in which people interpret reality in an abnormal situation is schizophrenia. A combination of extremely disordered thoughts, delusions, and hallucinations occurs due to schizophrenia, and the person's daily functions are seriously impaired due to this disease. For general cognitive activity analysis, electroencephalography signals are widely used as a low-resolution diagnostic tool. This study aimed to diagnose schizophrenia using the transfer learning method by including the EEGs of 73 patients diagnosed with schizophrenia, and 67 patients from the healthy group. Material and Method: In the first step of the study, digital electroencephalography signal data was converted into spectrograms to make them usable. In the classification phase, ResNet18, ResNet50 and EfficientNet models, which are FastAI, and Convolutional Neural Network (CNN) based deep learning models, were used. Results: Despite the complexity of electroencephalography data, CNN-based models in the study were successful in capturing different aspects of neurophysiological activity. The best performance was obtained from the ResNet-50 model with an accuracy rate of 97%. Afterwards, the classification process was finalized with 95% ResNet-18, and 83% EfficientNet models, respectively. Conclusion: It is thought that the classification performance of the result obtained in the application is promising and may be a guide for future studies. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Psychiatry is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Psychiatry is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Digital technologies help to monitor patients remotely, collect medical data, recognize the disease and increase awareness through psychoeducation and self-help applications. However, literature on the utilization of digital technologies among psychiatric patients is scarce. The aim of this study was to investigate the prevalence of the use of digital technology in patients applying to psychiatry outpatient clinic and its distribution according to diagnoses. Material and Methods: Between September-November 2023, 500 patients who applied to the XXXXX University Faculty of Medicine Psychiatry Outpatient Clinic and volunteered to participate were included in the study. After the psychiatric interviews were completed, a questionnaire was filled out asking about the characteristics of the use of mobile technologies, internet, social media and health applications. Results: Of the study group, 69.4% were female (n=347) and the mean age was 33.9 (±13.01) years. The educational status of 50.4% of the participants was university or master’s degree. While 96% of the participants used smartphones, 16% used wearable technology (n=80). Internet usage rate was 94.8% and social media usage rate was 91%. When 251 people who did not use any health application but would like to use one were asked which features they would like to have in the application they would like to use, 78.8% stated that they would like to create an appointment, 67.7% would like an appointment time reminder, 59.7% would like drug side effect query, 55.7% would like their physician to have access to their health information, and 54.9% would like online psychotherapy. Conclusion: The prevalence of smartphone and internet use among patients admitted to psychiatry is similar to the national population. There is an unmet need in terms of health applications for the psychiatric patient group. Considering the desired characteristics of health applications, it should be taken into account that there are different demands in psychiatric diagnosis groups. [ABSTRACT FROM AUTHOR]

Objective: Schizophrenia is a chronic mental disorder that reduces quality of life, causes deterioration in social and occupational functioning, and requires continuous care for psychosocial rehabilitation. The aim of this study was to investigate functional improvement, life satisfaction, and drug side effects in patients with schizophrenia and schizoaffective disorder using depot antipsychotics, oral antipsychotics, or both. Methods: The study included 162 patients with clinically stable schizophrenia and schizoaffective disorder who were regularly followed up at the Rize Community Mental Health Center for at least 1 year. The Satisfaction with Life Scale (SLS), Glasgow Antipsychotic Side-Effect Scale (GASS), and Functional Remission of General Schizophrenia (FROGS) scale were administered to patients with available sociodemographic and clinical data. Results: There were significant differences between the groups with respect to age at onset, number of hospitalizations, and gender. The mean GASS score of patients using both depot and oral antipsychotics was significantly higher than that of those using only depot antipsychotics. There was no significant difference between the groups in terms of mean SLS, total FROGS scores, and sub-dimension FROGS scores. Conclusion: It was concluded that it would be appropriate to prefer depot antipsychotics in the presence of poor prognostic factors such as medication non-adherence, frequent hospitalization, and lack of insight. There is a need for multicenter prospective studies with longer follow-up of patients for side effects, life satisfaction, quality of life, and functional improvement to achieve more significant results. [ABSTRACT FROM AUTHOR]

Social cognitive functions make it possible to correctly recognize and interpret the emotions and mental states of others in the social environment, to understand their intentions correctly and to react accordingly. Therefore, these functions arecritical for healthy social interactions and professional success in human life. Social cognitive functions are impaired in many psychiatric and neurological diseases and this impairment negatively affects almost all areas of patients' lives, albeit in different dimensions. According to research findings revealing the relationship between social cognition and social functioning, social cognition should be one of the treatment targets for many diseases. Recently, there has been increasing interest in interventions that target the improvement of these functions. In this article, these training programs, research findings and assessment tools used in these studies are discussed in the specific case of schizophrenia. [ABSTRACT FROM AUTHOR]

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Schizophrenia is one of the mental illnesses that prevent individuals from living their lives autonomously. Patients diagnosed with schizophrenia experience difficulties in their self-care and participation in social life and may need the care and support of another person. This care and support is mostly provided by their families. However, caregiving is a complex process and may cause the person to experience care burden. In this study, which was designed in qualitative design to determine the care burdens and needs of family members caring for individuals diagnosed with schizophrenia, 15 participants were reached through purposive random sampling. As a result of face-to-face interviews, it was seen that the participants faced objective and subjective care burden. It was understood that the problems related to the caregiving process were economic burden, physical and mental health problems of caregivers and social stigmatization. In addition, caregivers have concerns about what will happen to their patients if something happens to them and who will take care of them. Within the scope of the study, it is recommended to develop trainings, activities and social assistance systems specific to mental illnesses to increase the participation of individuals diagnosed with schizophrenia and caregivers in social life. [ABSTRACT FROM AUTHOR]

Cognitive dysfunction is the most important determinant for the recovery in schizophrenia and bipolar disorder. Cognitive dysfunction serves as an endophenotype although it may be a consequence of drug treatments. In schizophrenia starting from the first episode, pronounced cognitive defects such as cognitive flexibility, inhibition, verbal fluency, verbal memory and visual-motor processing are observable. These cognitive defects remain stable in the chronic phase of schizophrenia. On the other hand, cognitive dysfunctions in bipolar disorder patients have a heterogeneous pattern. One group of patients show no evidence of cognitive dysfunction while one group has limited dysfunction (of processing speed, attention, verbal learning and social cognition) and another one has wide spread dysfunctions as seen in schizophrenia. Despite its importance, no satisfactory results have been achieved in the treatment of cognitive dysfunctions in schizophrenia and bipolar disorder. In this article, the evaluation and treatment of the most frequent cognitive dysfunctions of schizophrenia and bipolar disorder are reviewed. [ABSTRACT FROM AUTHOR]

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Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mavi Atlas is the property of Mavi Atlas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To assess the effects of regular medication administration, diet, sleep, and physical activity provided by hospital care on inflammatory markers in schizophrenia patients. The primary hypothesis of our study is that the assembly of various factors, will reduce low-grade inflammation in a short period. Materials and Methods: This retrospective longitudinal study involved 106 patients diagnosed with schizophrenia who met the exclusion and inclusion criteria. Inflammatory markers such as neutrophil-to-lymphocyte Ratios (NLR), monocyte-to-lymphocyte ratios (MLR), platelet-to-lymphocyte ratios (PLR), C-reactive protein-to-albumin ratios (CAR), and systemic immune inflammation indices (SII) were calculated at the time of hospital admission and after three weeks. Results: The mean age of the participants was 39.0±13.1 years and the majority were male (n: 75). Reductions were observed in all inflammatory markers after three weeks. The CRP decreased from a median value of 2.6 (interquartile range (IQR): 1.1-5.3) to 1.90 (IQR: 0.85-3.30) (p=0.001, effect size=0.375). The CAR changed from 0.064 (IQR: 0.026-0.115) to 0.043 (IQR: 0.017-0.077) (p=0.005, effect size=0.371). The NLR demonstrated a significant reduction from 2.31 (IQR: 1.73-3.24) to 1.73 (IQR: 1.28-2.27) (p

The purpose of this study was to examine the effect of art therapy programme on the symptom levels of individuals diagnosed with schizophrenia. A 10- session art therapy program, each lasting 120 minutes, was applied to 10 male participants, aged between 29 to 65, and diagnosed with schizophrenia, for a total of 10 weeks. Follow-up measurements were taken 12 weeks after the end of the study together with pre-test, and post-test assessments. Beck's Depression Inventory (BDI) and Positive and Negative Syndrome Scale (PANSS) were given to the patients participating in the art therapy programme at the beginning and at the end of ten weeks. One group pretest - posttest control study design was used, and data were analyzed using the Wilcoxon Signed Rank test. In the analyses, it was found that the art therapy programme was effective in reducing the depressive symptoms and positive and negative symptom levels of the participants, and this effect continued in the follow-up measurement after 12 weeks. The results, limitations, and strengths of the research were discussed in the light of the literature. [ABSTRACT FROM AUTHOR]

Copyright of Celal Bayar Üniversitesi Saglik Bilimleri Enstitüsü Dergisi is the property of Celal Bayar University Health Sciences Institute Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi is the property of Istanbul Gelisim Universitesi Saglik Bilimleri Yuksekokulu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Uludag University Medical Faculty / Uludağ Üniversitesi Tıp Fakültesi Dergisi is the property of Journal of Uludag University Medical Faculty and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Zuclopenthixol is a typical antipsychotic drug used to treat schizophrenia and other psychotic disorders. Although effective and reliable, it can cause some side effects. The most common adverse effects are extrapyramidal symptoms such as akathisia, hyperkinesia, and hypokinesia. Zuclopenthixol decanoate is a long-acting form of the medication. The oculogyric crisis is the upward elevation of the gaze of both eyes within seconds to hours, resulting from the dystonic reaction of the eye muscles. It can occur as an adverse reaction to antipsychotic, antiemetic, antidepressant, antiepileptic, and antimalarial drugs. This article presents a case of tardive oculogyric crisis developed after using zuclopenthixol decanoate. [ABSTRACT FROM AUTHOR]

Strong association between homocysteine (Hcy) and metabolic syndrome (MetS) is documented in individuals with schizophrenia and it is suggested that alterations in Hcy levels might be secondary to metabolic changes induced by atypical antipsychotics (AA). Serum paraoxonase (PON-1) activity, which is negatively affected by increased Hcy concentrations are lower in schizophrenia, and this may impact the development of metabolic side effects. Forty-five subjects with schizophrenia and 43 healthy volunteers, matched according to age, gender, smoking habits, and MetS predictors, were enrolled in this study to examine how Hcy level, PON-1 activity, and MetS indicators influence each other in schizophrenic individuals on AA treatment. Serum Hcy concentrations were significantly higher (15 ± 8 μmol/L vs 12 ± 3 μmol/L), and PON activity tended to be impaired (182±82 U/L vs 216 ± 110 U/L) in schizophrenia. Serum Hcy concentrations were not different between subjects with and without metabolic syndrome in study (14±4 μmol/L and 16±9 μmol/L) and control groups (12±3 μmol/L and 13±7 μmol/L), respectively. Similarly, PON and aryl esterase (AE) activities were not different between subjects with and without metabolic syndrome in study (PON: 185±100 U/L and 181±76 U/L; AE: 84±34 kU/L and 89±20 kU/L) and control (PON: 215±111 U/L and 216±113 U/L; AE: 83±27 kU/L and 88±33 kU/L) groups, respectively. . Hcy levels and MetS predictors were not statistically correlated. Results indicate that schizophrenic subjects on AA treatment have increased levels of Hcy compared to healthy controls and this is not influenced by the presence of MetS. [ABSTRACT FROM AUTHOR]

When talking about recovery for schizophrenia patients, the absence of symptoms is satisfied and the concept of happiness is generally ignored. In our study, we aimed to compare the happiness levels of patients with schizophrenia who were followed up by the community mental health center (CMHC) and had case managers, and those with schizophrenia in remission who were followed only by the outpatient clinic and at the same time we compare the expression of emotion, which is thought to affect this happiness, the level of support perceived by the patient and the quality of life. Patients with schizophrenia who had regular CMHC follow-up for at least 1 year and had a case manager (CM) (n:100) and were in remission for at least 3 months (n:100) who were followed up in the outpatient clinic were included in the study. Subjective Happiness Scale (SHS), Perceived Available Support Scale (PASS), Quality of Life Scale (QLS), Level of Expressed Emotion Scale (LEES) were applied to both groups. SHS, PASS, LEES, QLS scores were statistically significantly different in the group with CM. A negative correlation was found between the subscales showing the Level of Expression of Emotion and SHS scores. A positive correlation was found between QLS and PASS scores and SHS scores. In the case of VY, it was determined that PASS scores had a mediating effect on SHS scores, but QLS scores did not have a mediating effect. It was determined that the levels of intrusiveness, emotional response and tolerance/expectation, which are subscales of LEES, had a mediating effect on SHS scores, but the levels of attitude towards illness did not have a mediating effect. For people with schizophrenia, happiness is an often overlooked concept when talking about recovery. In our study, we evaluated the effect of case management within the scope of CMHC service and found that it had a positive effect on the happiness of patients with schizophrenia. [ABSTRACT FROM AUTHOR]

Schizophrenia is one of the most debilitating mental disorders. Auditory hallucinations, which are known to be closely related to interpersonal relationships, are the most common type of hallucinations observed in the course of schizophrenia. Virtual reality has been developing in various fields with the development of computerized technologies and has started to appear in the field of clinical psychology in the form of virtual reality therapies. Avatar therapy is among the interpersonal-based virtual reality therapy models that focus on auditory hallucinations among the symptoms of schizophrenia. The aim of avatar therapy is to enable the person to have control over auditory hallucinations. Within the scope of this review study; the past, present and future of schizophrenia treatment, effective intervention methods in the treatment of schizophrenia, virtual reality therapy, the main outlines of the avatar therapy model, the effectiveness studies of avatar therapy and ethical issues were discussed. The results of the research on the effectiveness of avatar therapy reveal the need for further research in this field. [ABSTRACT FROM AUTHOR]

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Copyright of Humanistic Perspective is the property of Fuat Aydogdu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Online Turkish Journal of Health Sciences (OTJHS) / Online Türk Sağlık Bilimleri Dergisi is the property of Oguz KARABAY and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Visual illusions are popularly referred to as the phenomena where the eye sees something that is not there. The aim of this review is to show that illusions are not the occasional misinterpretations of the physical world. Illusions are critical to our understanding of perceptual processes. The cause of illusions can vary depending on the reflection or refraction of light, how the brain processes the information reaching the retina, or how the visual system works when perceiving depth. Illusions, which have inspired both artists and scientists, have been instrumental in our understanding of human perception and the functioning of the brain in general. At the beginning of this article, the classes that emerge from a scientific perspective will be defined in parallel with the hierarchical visual perception. Examples of illusions that inform us about the physiological (corresponding to the early stages of visual perception) processes and cognitive (corresponding to higher level stages of visual perception) strategies will be given, and the factors that may cause them will be examined. In the light of theoretical approaches and perceptual grouping concepts, I will discuss how these interpretations help us to understand the brain and human nature. Next, I will give examples of findings and applications in clinical populations to touch on the role of illusions in our understanding of visual perception in e.g. schizophrenia patients. [ABSTRACT FROM AUTHOR]

Oxytocin is a peptide hormone that is most known for its role in reproduction. However, many effects other than reproduction have been defined. The lifetime prevalence of mental disorders is approximately 20%, and they have a significant ratio among the diseases that lead to disability. Treatment resistance may cause the mental disorder to become chronic and increase disability. With the examination of the oxytocinergic system, both the elucidation of the etiology of the diseases and their evaluation as a new treatment option have come to the fore. In various studies, it has been desired to create a more effective treatment model by measuring the level of oxytocin in psychiatric disorders, examining its receptor, and applying exogenous oxytocin in the treatment. In this review, an overview of oxytocin's efficacy in treatment is presented by considering the relationship between psychiatric disorders and the oxytocinergic system [ABSTRACT FROM AUTHOR]

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Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Uludag University Medical Faculty / Uludağ Üniversitesi Tıp Fakültesi Dergisi is the property of Journal of Uludag University Medical Faculty and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Cardiovascular risk increases in patients with schizophrenia. In our study, it was aimed to predict the 10-year risk of developing cardiovascular disease using the Framingham risk score in schizophrenia patients living in nursing homes Materials and Methods: In our study, the sociodemographic and clinical characteristics of schizophrenia patients living in nursing homes, such as age, gender, educational status, duration of disease, and treatments used, and Framingham risk scoring which included age, gender total cholesterol, HDL, smoking status, systolic blood pressure, and presence of diabetes mellitus. were used in the calculation of cardiovascular risk. Also, the results of the General Assessment of Functioning and Clinical Global Impression disease severity scale were recorded in order to determine the functionality and severity of the disease. Results: 51 patients with schizophrenia were included, and the Framingham risk score of the patients was calculated as 4.65±4.63. While Framingham risk scores were significantly correlated with disease duration (r=0.284, p=0.044), age (r=0363, p=0.01) and length of stay in nursing home (r=0.538, p

Objective: In this study, we aimed to evaluate the levels of FSH, LH, estradiol, testosterone, progesterone, and prolactin in patients with schizophrenia and majör depressive disorder. Material and Method: Our study included a total of 80 female patients diagnosed with schizophrenia and major depressive disorder according to DSM-IV. Twenty healthy women were included in order to create a control group. Hormonal parameters were studied in routine blood samples taken between 08:00 and 11:00 in the patient and control groups. Results: There was no statistically significant difference between the patient and control groups in terms of mean age, weight, body mass index and menstrual phases. (p >0.05). Serum estradiol level was higher in the control group than in the patient groups (p <0.05). In addition, we found significantly higher serum testosterone levels in schizophrenic patients (with and without medication) compared to those with depressive disorder (with and without medication) and the control group (p <0.05). Also prolactin levels in schizophrenic patients taking medication were significantly higher than those in the other patient groups and control group (p <0.05). On the other hand, serum progesterone levels in schizophrenic patients who did not take medication were statistically significantly lower than the cases in other groups (p <0.05). Conclusion: In our study, measurement of low estradiol and high serum testosterone levels in schizophrenic patients shows that gonadal hormones play a very important role in the onset of the disease. Another finding in our study is that serum estradiol level was found to be higher in women with major depressive disorder compared to the control group. [ABSTRACT FROM AUTHOR]

Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Amaç: Bu çalışmada uzun etkili antipsikotik ilaç formları (uzun etkili paliperidon palmitat, risperidon depo ve zuklopentiksol depo) kullanan hastalarda cinsel işlev bozuklukları, vücut kitle indeksi, karaciğer fonksiyon testleri ve prolaktin düzeylerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışmaya şizofreni tanılı ve uzun etkili antipsikotik tedavisi alan hastalar dahil edildi. Tüm katılımcılara demografik veri formu, Pozitif ve Negatif Sendrom Ölçeği (PANSS), Calgary Şizofrenide Depresyon Ölçeği (CŞDÖ) ve Arizona Cinsel Yaşantılar Ölçeği (ACYÖ) uygulandı. Ardından üre, kreatinin, karaciğer fonksiyon testleri, kolesterol ve prolaktin düzeylerini değerlendirmek için venöz kan örnekleri alındı. Bulgular: Çalışmaya 95 hasta dahil edildi. Dahil edilenlerin 79’u erkek (%83.2) ve 16’sı kadındı (%16.8). Tüm hastaların yaş ortalaması 36.77±10.24 yıl idi. Vücut kitle indeksleri ortalaması ise 27.06±4.95 kg/m2 idi. Gruplar arasında ACYÖ ve CŞDÖ skorları açısından farklılık saptanmadı. Prolaktin değeri paliperidon depo kullanan hastalarda zuklopentiksol depo kullanan hastalardan yüksek olarak hesap edilmiştir. Sonuç: Sonuçlarımıza göre cinsel işlevleri etkileyen prolaktin değerleri, hastalar semptom belirtmese de uzun etkili antipsikotik kullanan hastalarda göz önünde bulundurulmalıdır. Uzun etkili antipsikotik kullanımının hem prolaktin değerleri hem de diğer laboratuvar parametrelerine olan etkileri konusunda ileri araştırmalar yapılmalıdır.

Purpose: The aim of this study is to examine the relationship between thyroid hormone levels and positive, negative, general, and cognitive symptoms in euthyroid patients with psychosis. Materials and Methods: Thirty-three schizophrenia patients were included in this cross-sectional study. Sociodemographic and clinical data of the participants, positive and negative symptoms assessment scale (PANSS), general assessment of functionality scale (GAF), and clinical global impression scale (CGI) scores were recorded. The relationships between TSH, fT3, and fT4 levels and cognitive performances of patients which is measured via a neurocognitive battery consisting of Trail Making Test (TMT) A, TMT B, verbal fluency test (VFT), digit span (DS), forward and backward, and Wisconsin Card Sorting Test (WCST) were investigated. Results: Significant correlations were found between fT3 levels and WCST performances. fT3 levels was significantly correlated with the number of categories achieved in WCST (r=.508; p=0.003). A significant correlation was found between fT4 levels and TMT B (r=-.376; p=0.031) and VFT (p=.355; p=0.043) performances. In the linear regression model, it was found that fT3 levels significantly predicted the number of categories achieved in WCST (UB=1.680; p=0.029). Conclusion: The results of our study suggested that fT3 has more significant effects, primarily on executive functions, compared to T4.

Copyright of Turkiye Klinikleri Journal of Forensic Medicine & Forensic Sciences / Türkiye Klinikleri Adli Tıp ve Adli Bilimler Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: Unhealthy lifestyle factors make up a significant proportion of the factors that cause high morbidity and mortality risk. The life span of patients with schizophrenia is 10-20 years less than that of the general population due to lifestyle-related diseases. The aim of this study is to compare with healthy individuals the nutritional habits, nutritional status, and physical activity levels of schizophrenic patients. Materials and Methods: The study was conducted on 25-55-year-old 40 patients diagnosed with schizophrenia or schizoaffective disorders and 30 healthy controls matched for age and gender. Data on sociodemographic characteristics and nutritional habits, three-day food consumption and a 24-hour retrospective physical activity records were collected. Results: Dietary energy, protein, total fat, cholesterol, and fiber intakes were found to be lower only in female schizophrenia patients than in their healthy counterparts. Patients with schizophrenia presented with lower intakes of dietary thiamine, niacin, iron, and zinc compared to healthy controls. Patients with schizophrenia recorded lower physical activity levels compared to healthy controls (1.59±0.22 and 1.77±0.17 respectively). Conclusion: Unhealthy diet and sedentary life observed in patients with schizophrenia can lead to the development of serious medical comorbidities and to an increase in the side effects of antipsychotic medications. Therefore, patients with schizophrenia should be encouraged to consume healthy diets and undertake more physical activities requires the multidisciplinary approach of specialized professionals. [ABSTRACT FROM AUTHOR]

Copyright of Gümüshane Üniversitesi Saglik Bilimleri Dergisi is the property of Gumushane University, Faculty of Health Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)