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243 results on '"Șirli, Roxana"'

7. WFUMB Review Paper. Incidental Findings in Otherwise Healthy Subjects, How to Manage: Liver.

Author

Șirli, Roxana, Popescu, Alina, Jenssen, Christian, Möller, Kathleen, Lim, Adrian, Dong, Yi, Sporea, Ioan, Nürnberg, Dieter, Petry, Marieke, and Dietrich, Christoph F.

Subjects
*LIVER tumors, *CIRRHOSIS of the liver, *HEMANGIOMAS, *ULTRASONIC imaging, *AGE distribution, *CALCINOSIS, *MAGNETIC resonance imaging, *SYMPTOMS, *LIVER diseases, *LIVER cells, *LIVER, *DISEASE risk factors
Abstract

Simple Summary: This review paper deals with incidentally found focal liver lesions (IFLLs) in otherwise healthy subjects, which is a frequent occurrence in daily practice. The clinical presentation and the imaging aspects play an important role in deciding whether and what further evaluation is required. In low-risk patients (i.e., those without a history of malignant or chronic liver disease or related symptoms, younger than 40 years old), more than 95% of IFLLs are benign. Shear Wave liver Elastography of the surrounding liver parenchyma should be considered to exclude liver cirrhosis and for further risk stratification. If an IFLL in a low-risk patient has a typical appearance on a B-mode ultrasound of a benign lesion, no further imaging is needed. Contrast-Enhanced Ultrasound (CEUS) should be considered as the first-line contrast imaging modality to differentiate benign from malignant IFLLs. In high-risk patients (i.e., with chronic liver disease or an oncological history), each IFLL should initially be considered as potentially malignant, and every effort should be made to confirm or exclude malignancy. An incidental focal liver lesion (IFLL) is defined as a hepatic lesion identified in a patient imaged for an unrelated reason. They are frequently encountered in daily practice, sometimes leading to unnecessary, invasive and potentially harmful follow-up investigations. The clinical presentation and the imaging aspects play an important role in deciding if, and what further evaluation, is needed. In low-risk patients (i.e., without a history of malignant or chronic liver disease or related symptoms), especially in those younger than 40 years old, more than 95% of IFLLs are likely benign. Shear Wave liver Elastography (SWE) of the surrounding liver parenchyma should be considered to exclude liver cirrhosis and for further risk stratification. If an IFLL in a low-risk patient has a typical appearance on B-mode ultrasound of a benign lesion (e.g., simple cyst, calcification, focal fatty change, typical hemangioma), no further imaging is needed. Contrast-Enhanced Ultrasound (CEUS) should be considered as the first-line contrast imaging modality to differentiate benign from malignant IFLLs, since it has a similar accuracy to contrast-enhanced (CE)-MRI. On CEUS, hypoenhancement of a lesion in the late vascular phase is characteristic for malignancy. CE-CT should be avoided for characterizing probable benign FLL and reserved for staging once a lesion is proven malignant. In high-risk patients (i.e., with chronic liver disease or an oncological history), each IFLL should initially be considered as potentially malignant, and every effort should be made to confirm or exclude malignancy. US-guided biopsy should be considered in those with unresectable malignant lesions, particularly if the diagnosis remains unclear, or when a specific tissue diagnosis is needed. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals

Author

Bazerbachi, Fateh, Haffar, Samir, Wang, Zhen, Cabezas, Joaquín, Arias-Loste, Maria Teresa, Crespo, Javier, Darwish-Murad, Sarwa, Ikram, M. Arfan, Olynyk, John K., Gan, Eng, Petta, Salvatore, Berzuini, Alessandra, Prati, Daniele, de Lédinghen, Victor, Wong, Vincent W., Del Poggio, Paolo, Chávez-Tapia, Norberto C., Chen, Yong-Peng, Cheng, Pin-Nan, Yuen, Man-Fung, Das, Kausik, Chowdhury, Abhijit, Caballeria, Llorenç, Fabrellas, Núria, Ginès, Pere, Kumar, Manoj, Sarin, Shiv Kumar, Conti, Fabio, Andreone, Pietro, Sirli, Roxana, Cortez-Pinto, Helena, Carvalhana, Sofia, Sugihara, Takaaki, Kim, Seung Up, Parikh, Pathik, Chayama, Kazuaki, Corpechot, Christophe, Kim, Kang Mo, Papatheodoridis, George, Alsebaey, Ayman, Kamath, Patrick S., Murad, M. Hassan, and Watt, Kymberly D.

Published
2019
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20. Contrast-Enhanced Ultrasonography with Arrival Time Parametric Imaging as a Non-Invasive Diagnostic Tool for Liver Cirrhosis

Author

Lupușoru, Raluca, primary, Sporea, Ioan, additional, Rațiu, Iulia, additional, Lungeanu, Diana, additional, Popescu, Alina, additional, Dănilă, Mirela, additional, Mare, Ruxandra, additional, Marc, Luciana, additional, Lascău, Andrada, additional, Moga, Tudor Voicu, additional, Bende, Felix, additional, Ghiuchici, Ana-Maria, additional, and Șirli, Roxana, additional

Published
2022
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28. The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: A retrospective multicentre study

Author

Bota, Simona, Sporea, Ioan, Peck-Radosavljevic, Markus, Sirli, Roxana, Tanaka, Hironori, Iijima, Hiroko, Saito, Hidetsugu, Ebinuma, Hirotoshi, Lupsor, Monica, Badea, Radu, Fierbinteanu-Braticevici, Carmen, Petrisor, Ana, Friedrich-Rust, Mireen, Sarrazin, Christoph, Takahashi, Hirokazu, Ono, Naofumi, Piscaglia, Fabio, Marinelli, Sara, D’Onofrio, Mirko, Gallotti, Anna, Salzl, Petra, Popescu, Alina, and Danila, Mirela

Published
2013
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33. Acoustic Radiation Force Impulse Elastography for fibrosis evaluation in patients with chronic hepatitis C: An international multicenter study

Author

Sporea, Ioan, Bota, Simona, Peck-Radosavljevic, Markus, Sirli, Roxana, Tanaka, Hironori, Iijima, Hiroko, Badea, Radu, Lupsor, Monica, Fierbinteanu-Braticevici, Carmen, Petrisor, Ana, Saito, Hidetsugu, Ebinuma, Hirotoshi, Friedrich-Rust, Mireen, Sarrazin, Christoph, Takahashi, Hirokazu, Ono, Naofumi, Piscaglia, Fabio, Borghi, Alberto, D’Onofrio, Mirko, Gallotti, Anna, Ferlitsch, Arnulf, Popescu, Alina, and Danila, Mirela

Published
2012
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41. Diagnosis of malignant biliary obstruction: pondering over the ERCP, MRCP and histology

Author

Rațiu, Iulia, primary, Lupușoru, Raluca, additional, Lungeanu, Diana, additional, Popescu, Alina, additional, Sporea, Ioan, additional, Goldiș, Adrian, additional, Dănilă, Mirela, additional, Miuțescu, Bogdan, additional, Moga, Tudor, additional, Barbulescu, Andreea, additional, Tăban, Sorina, additional, Dema, Alis, additional, and Șirli, Roxana, additional

Published
2022
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43. Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study

Author

Rațiu, Iulia, primary, Lupușoru, Raluca, additional, Vora, Prateek, additional, Popescu, Alina, additional, Sporea, Ioan, additional, Goldiș, Adrian, additional, Dănilă, Mirela, additional, Miuțescu, Bogdan, additional, Barbulescu, Andreea, additional, Hnatiuc, Madalina, additional, Diaconescu, Razvan, additional, Tăban, Sorina, additional, Lazar, Fulger, additional, and Șirli, Roxana, additional

Published
2021
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46. Quantification of Liver Fibrosis, Steatosis, and Viscosity Using Multiparametric Ultrasound in Patients with Non-Alcoholic Liver Disease: A “Real-Life” Cohort Study

Author

Popa, Alexandru, primary, Bende, Felix, additional, Șirli, Roxana, additional, Popescu, Alina, additional, Bâldea, Victor, additional, Lupușoru, Raluca, additional, Cotrău, Radu, additional, Fofiu, Renata, additional, Foncea, Camelia, additional, and Sporea, Ioan, additional

Published
2021
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