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Objective: To evaluate modern diagnostic methods in identifying extrapulmonary forms of tuberculosis (EPT) with drug resistance. Methods: To examine the time limits and identification of circumstances and diagnostics in EPT considered TB-06 registration forms for 2017, № 003/U (case history) of the 56 primary diagnosed patients registered for 2017-2018 in the National Center for Phthisiology. Results: The incidence of EPT in Kyrgyzstan in 2017 was 23.9 per 100 thousand of the population. According to TB-06 forms, extrapulmonary tuberculosis is only 1650 cases. 862 sowings were carried out, of which 503 were negative (58%). Positive results of sowings were 359 (42%). In 333 cases, a drug sensitivity test was performed: resistant forms were 192 (57.6%) and sensitive – 141 (42.4%) cases. Conclusion: From modern methods noted the high use of BactecMGIT and molecular genetic methods of research, which shortens the diagnosis time and promotes to the timely start of the treatment process.

Objective: To study the clinical course of multiple drug resistance in patients with tuberculous spondylitis in the Kyrgyz Republic. Methods: Analyzed 877 medical histories of patients with tuberculous spondylitis of the cervical, thoracic, lumbar and lumbosacral spine, which was on treatment in the Department of Bones and Joints Tuberculosis Surgery from 2013 to 2017. Results: It is established that 715 patients (81.5%) had a sensitive form of tuberculous spondylitis; 153 (17.4%) is primarily resistant and 9 (0.8%) is a secondarily resistant form. In the group of patients in the sensitive form of tuberculosis men were 370, women 345, and among the patients with the resistant form of tuberculous spondylitis of men and women were 86 and 76 people respectively. Conclusion: Over the period of 2013-2017 y., the Kyrgyz Republic marked the growth in multi-drug resistant forms of tuberculous spondylitis with the rapid development of formidable neurological complications, such as meningitis, paresis, paraparesis, paralysis, and dysfunctions of pelvic organs.