Objective: To investigate the clinical value of stress percussion machine in promoting fracture healing after external fixation for tibial fractures. Methods: 132 cases of patients with tibial fractures were selected as the study object and were randomly divided into the study group and control group by randomsampling method, 66 cases in each group. The control group received postoperative routine intervention regimen, while the study group received stress percussion machine for percussion therapy. The rates of nonunion and delayed union, fracture healing time, full weight-bearing time, Lane-Sandhu X-ray score at the 6th month after fractures and Johner- wruh assessment were recorded and compared between two groups. Results: ① The rates of nonunion and delayed union in the study group (4.5 %, 7.6 %) were significantly lower than those in the control group (19.7 %, 22.7 %) (P<0.05); ②The fracture healing time and full weight-bearing time of study group [(82.6± 9.2) d, (101.5± 10.5) d] were significantly shorter than those of the control group [105.9± 10.3) d, (122.4± 10.3) d] (P<0.05). At the 6th month after fractures, Lane-Sandhu X ray score of the control group [(2.2± 0.5)] was significantly lower than that of the study group [(3.0± 0.5)] (P<0.05); ③At the 6th month after fractures, the excellent rate of Johnerwruh (90.1%) was significantly higher than that of the control group (75.8%) (P<0.05). Conclusion: To apply stress percussion machine in rehabilitation therapy of patients with tibial fractures after external fixation could effectively shorten the fracture healing time, improve the rate of fracture healing and is beneficial to accelerate callus growth rate and promote the outcomes. [ABSTRACT FROM AUTHOR]