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本实验旨在观察17β-雌二醇（17β-estradiol,E2）的快速舒血管效应并探讨其内皮依赖和非内皮依赖的作用机制。【方法】采用MyodapandMyodata血管张力仪进行体外血管灌流实验,测量鼠离体胸主动脉环等长张力。【结果】E2能浓度依赖性地快速舒张血管,浓度为10-9～10-6mol/L时,去内皮的血管环舒张程度明显小于内皮完整的血管环,而当E2浓度增加至10-5mol/L时,去内皮的血管环与内皮完整的血管环舒张程度无差异;在内皮完整的血管环,分别用左旋硝精氨酸甲酯（NG-nitro-L-arginine methyl ester,L-NAME）、亚甲蓝（methylene blue,MB）、他莫昔芬（tamoxifen）、甲基-β-环糊精（methyl-β-cyclodextrin,MβCD）预孵育均能显著抑制E2（10-6mol/L）的舒血管效应;而在去内皮的血管环,E2（10-5mol/L）能抑制CaCl2在无钙高钾溶液中诱发的血管收缩。【结论】E2的快速舒血管效应,具有内皮依赖性,与雌激素受体介导内皮释放一氧化氮（nitricoxide,NO）有关,且质膜微囊结构必须完整,而当E2浓度较高时主要是通过抑制细胞外的钙内流直接舒张血管，为非内皮依赖性。

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Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Task allocation mechanism plays an important role on crowdsourcing task quality. However? the existing allocation methods do not consider the bilateral user preferences of crowdsourcing, the accuracy of the allocation results remains to be improved? and there are many crowdsourcing users who are not satisfied with the current allocated crowdsourcing tasks, causing the phenomenon of low quality of crowdsourcing task accomplishment. Therefore a crowdsourcing task allocation method based on preference matching is proposed. Firstly? this method compute satisfaction and construct satisfaction matrix by using the preference of crowdsourcing tasks and workers. Secondly? by referring to the idea of stable matching and taking into account the bilateral preferences of crowdsourcing subjects? the method makes crowdsourcing subjects as satisfied as possible with the current allocation objects so as to guarantee the stability of the allocation results. Then夕 by using the idea of stable matching, the crowdsourcing task allocation problem is modeled as an optimization problem to find the maximum satisfaction of tasks under stable matching rules. Finally? greedy algorithm is used to solve the problem and a crowdsourcing task allocation scheme is obtained. The rationality and effectiveness of the method are verified by experiments, which shows that the method improves the accuracy of the allocation and effectively reduces the number of invalid allocations, thus improving the quality of crowdsourcing task allocation. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Image & Graphics is the property of Editorial Office of Journal of Image & Graphics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)