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To investigate the effects of lenvatinib combined with transcatheter arterial chemoembolization (TACE) on tumor markers apoptotic molecules serum sialic acid transferase 1 (ST6Gal1) angiopoietin-2 (ANG-2) and hepatocyte growth factor(HGF) in patients with unresectable hepatocellular carcinoma. 114 patients with unresectable hepatocellular carcinoma who were admitted to Sichuan Mianyang 404 Hospital from March 2020 to December 2022 were divided into control group (n=57 TACE treatment) and study group (n=57 lenvatinib combine with TACE treatment) by random number table method. The efficacy tumor markers [alpha-fetoprotein (AFP) carbohydrate antigen 199 (CA199) carcinoembryonic antigen (CEA)] serum apoptotic molecules [B-celllymphoma-2-associated X protein (Bax) B-cell lymphoma-2 gene (Bcl-2) survivin (Survivin) cysteine aspartic protease-4 (Caspase-4)]and serum ST6Gal1 ANG-2 HGF levels were compared between two groups and the incidence of adverse reactions during treatment was observed. Compared with control group the total clinical effective rate in study group was higher (P<0. 05). Compared with control group the levels of AFP CA199 and CEA in study group were lower after treatment (P<0. 05). Compared with control group the levels of Bcl-2 and Survivin in study group were lower after treatment and the levels of Bax and Caspase-4 were higher (P<0. 05). Com-pared with control group the levels of ST6Gal1 ANG-2 and HGF in study group were lower after treatment (P<0. 05). There was no difference in the total incidence of adverse reactions between two groups (P>0. 05). Lenvatinib combined with TACE for patients with unresectable hepatocellular carcinoma which can improve the clinical treatment effect regulate the levels of tumor markers, apoptotic molecules and serum ST6Gal1 ANG-2 and HGF with good safety [ABSTRACT FROM AUTHOR]

Copyright of Journal of Materials Engineering / Cailiao Gongcheng is the property of Journal of Materials Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Petrochemical Universities / Shiyou Huagong Gaodeng Xuexiao Xuebao is the property of Journal Editorial Department Of Liaoning Shihua University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Rural Water & Hydropower is the property of China Rural Water & Hydropower Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Geography & Geographic Information Science is the property of Geography & Geo-Information Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Zhengzhou University (Natural Science Edition) is the property of Journal of Zhengzhou University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hebei University of Science & Technology is the property of Hebei University of Science & Technology, Journal of Hebei University of Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Basic Sciences Journal of Textile Universities / Fangzhi Gaoxiao Jichu Kexue Xuebao is the property of Basic Sciences Journal of Textile Universities and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Anaerobic fermentation is an important technical way to deal with organic wastes in China. However, in the process of treating organic wastes under high load conditions by anaerobic fermentation technology, it is easy to cause anaerobic fermentation operation unstable and the efficiency of organic waste treatment is not high due to the inhibitory substances such as the high concentration of organic acid and ammonia nitrogen. Biochar is a multi-aperture carbonaceous material formed by high-temperature pyrolysis of biomass materials under the anaerobic or anoxic conditions. Biochar has many excellent properties, such as the high specific surface area, good conductivity, mass transfer and heat transfer performance. At the same time, biochar also contains a lot of ash, and the abundant ash contains a lot of elements such as calcium and magnesium, which makes the biochar have good adsorption and ion exchange performance. As an additive for anaerobic fermentation, it can effectively improve the pH value, alkalinity and the acid buffer capacity of the anaerobic fermentation system, and alleviate the inhibition of the excessive production of methane by the volatile fatty acids during the lag period. It can cause the adhesion of microorganisms and had a certain microbial carrier effect. Addition of biochar can effectively solve the problems of the low efficiency of gas production and unstable fermentation in current anaerobic fermentation, and biochar is now widely used in anaerobic fermentation technology research. In recent years, the research status of domestic and foreign showed that biochar could effectively strengthen anaerobic fermentation under certain conditions and improve the treatment efficiency of organic wastes in anaerobic fermentation process. However, for the biochar-enhanced anaerobic fermentation technology approach, there were still no systematic reviewed and reported. In this paper, the chemical composition, surface pore structure, key factors of surface functional groups and important ways of biochar-enhanced anaerobic fermentation technology of biochar materials were systematically analyzed and summarized. Based on the physical and chemical properties of biochar materials, biochar was described. For example, the effects of different types, different particle sizes and different amounts of additive biochar on anaerobic fermentation. And the intensive pathways of anaerobic fermentation technology mainly included: Biochar could effectively improve the buffer capacity of the system, it had a certain microbial carrier function, and it could strengthen the interspecific electron transport of microorganisms. On this basis, the focus of research on anaerobic fermentation technology of organic wastes in the future was proposed. At the same time, it also provided support for the in-depth development of biochar enhanced anaerobic fermentation technology. [ABSTRACT FROM AUTHOR]

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Engineering & Science / Jisuanji Gongcheng yu Kexue is the property of Computer Engineering & Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In China, the production of corn straw annually has become a problem, because of lack of resource utilization. Producing biogas with corn straw is one of the available ways to solve this problem. However, this way still not be promoted widely. The main reason is the low rate of return with the traditional craft. Integrating advanced technology of straw biogas plant is the key for sustainable development of straw biogas industry, focusing on the improvement of engineering economy. Our study team had conducted many researches on the key steps of straw biogas plant, such as straw pretreatment, straw anaerobic fermentation, agitation optimization, biogas slurry recirculation, and developed several key technologies. The corn stalk has a compact structure, thus it was not able to be degraded easily in the anaerobic fermenter. The mixture of Saccharomycetales, Sordariales, Hypocrees, Lactobacillales and other microbial as the pretreatment agent were applied in our studies study. And the pretreatment was carried out in a continuous mixed reactor with continuous aeration. Under these conditions, the degradation rate of straw lignocellulose could reach above 48%. After pretreatment, the gas production rate of straw was increased by 20%, and the peak-time of gas production was shortened by more than 3 days. The CSTR and vertical plug flow (VPF) fermentation reactor were compared in this study. The results showed that the CSTR fermentation technology was more common and mature. The reactor structure, the structure of the stirring device, the stirring style and the baffle plate all had a significant influence on the mixing effect of the CSTR. Our study team had developed an optimization method using a CFD simulation. The anaerobic fermentation only with corn straw, the anaerobic process was not stable because of easy acidification and nutritional imbalance. In our research, we applied the recirculation of biogas slurry to the anaerobic fermentation process. The results showed that recirculation of biogas slurry could help keeping the fermentation process stable. Under the conditions with recirculation of 80% biogas slurry, the biogas production rate of maize silage was increased by 97%-180%. Based on these single technologies, we proposed an integrated technology of “stalk silage-micro aerobic hydrolysis pretreatment-CSTR medium temperature & stirring optimization-biogas slurry near fully recirculation”. The integrated technology had been employed in the Tianlong biogas plant in Sanhe, Hebei Province. The operation results showed that the biogas production rate of straw reached 555.78 m3/t with a relatively high CH4 concentration of 56% and low H2S concentration of 162×10-6, which proved that the integrated technology could be stable and efficient t in the actual operation of a large-scale biogas plant. [ABSTRACT FROM AUTHOR]

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tanshinone II A is a kind of phenanthraquinone derivatives derived from Salvia miltiorrhiza , which is one of the main active components of Danshen to play the protective role of cerebral ischemic injury. Inflammation plays an important role in the pathogenesis of cerebral ischemia. In recent years. much evidence shows that immune cells , adhesion molecules. inflammatory mediators have been involved in the pathogenesis of immune response in the central nervous system through induetion or regulation of cerebral ischemia. In this paper, the research progress of mechanism of inflammatory response of tanshinone II A after cerebral ischemia was reviewed. which provided a new idea for the study of the protective mechanism of tanshi-II A in cerebral ischemia. [ABSTRACT FROM AUTHOR]

Objective To study the protective effect of Fu-Yuan-Xing-Nao decoction (FYXND) on rats with middle cerebral ischemia reperfusion injury. Methods Male Sprague-Dawley rats were randomly divided into sham, ischemia-reperfusion, and low, middle, high FYXND dose (5.5, 11, 22 g/kg) groups. Rats model was induced by 2 h of middle cerebral artery occlusion and 24 h reperfusion. The neurological deficit score of each group was evaluated. The infarct size was measured by the 2,3,5-triphenyltetra-zolium(TTC) chloride staining assay. The pathological changes of brain tissue were observed by HE staining assay. The changes of Nissl bodies were observed by Nissl staining. Tunnel staining was used to observe the apoptosis of neurons in brain. Serum levels of superoxide dismutase (SOD)and Malondialdehyde (MDA) were measured. Results Compared with the model group, neurological outcomes were improved in all three groups of low, middle and high FYXND dose (5.5, 11, 22 g/kg). Significantly reduced infarct brain volume was observed with TTC staining in all three FYXND groups. The results from HE staining assay indicated that the pathological structure of brain tissue was improved in the treatment groups. The numbers and morphology of Nissl corpuscles in the treated group were also improved based on the results of Nissl staining. Both the Tunnel staining positive cells and the rate of apoptosis were decreased. Compared with the model group, FYXND increased the rat serum SOD level and decreased the MDA level. Conclusion FYXND has protective effects on cerebral ischemia reperfusion injury in rats. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To observe the effect of probiotics in the treatment of enteral nutrition-associated diarrhea. Methods From June 2016 to June 2017，90 cases with enteral nutrition-associated diarrhea in the hospital were randomly di- vided into the divided group（27cases），the combined group（24cases）and the control group（25cases）.The divided group was injected with nutrient solution and probiotics separately，and the combined group was injected with nutrient solution together with probiotics，while the control group was treated with montmorillonite.The total effective rate，frequency of diarrhea and total course of disease on the third，fifth，seventh day were analyzed in the 3 groups.Results There was no significant difference in the total effective rate of the third，seventh day between the divided group and the control group（P>0.05）.The total effective rate of the fifth day of the treatment group was significantly higher than that of the control group（P=0.006）.There was no significant difference in the total effective rate of the third，fifth day between the combined group and the control group（P>0.05）.The total effective rate of the combined group was significantly lower than that of the control group for seventh days，and the difference was statistically significant（P=0.000）.The diarrhoea frequency of the divided group was significantly lower than that of the control group on the third，fifth day，while the diarrhea frequency of the combined group was significantly higher than that of the control group on the seventh day，and the difference was statistically significant（P<0.05）.The total course of disease in the divided group was significantly lower than that in the control group，whiel the total course of disease in the combined group was signifi- cantly higher than that in the control group，and the difference was statistically significant（P<0.05）.Conclusion The separa- tion of probiotics and nutrient solution can significantly improve the total effective rate of enteral nutrition-associated diarrhea， reduce the number of diarrhea and shorten the total course of disease. [ABSTRACT FROM AUTHOR]