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目的 分析首次青年缺血性卒中患者出院、发病90d预后不良的相关危险因素。 方法 回顾性纳入18～45岁、发病72 h内的首次缺血性卒中患者，收集患者人口学信息、血管危险因素、实验室检查结果、入院和出院时NIHSS，以出院时和发病90 d mRS≥2分为预后不良，分别比较预后不良组和预后良好组危险因素的差异和病因分型特点，并采用多因素logistic回归分析出院和90 d预后不良的独立危险因素。 结果 研究共纳入691例首次青年缺血性卒中患者，出院预后不良234例（33.9%），90 d预后不良154例（22.3%）。出院时预后的独立危险因素包括入院时高NIHSS（OR 2.76，95%CI 2.07～3.68，P

目的 探讨TG水平对社区高血压患者认知功能的影响。 方法 本研究为基于社区人群的前瞻性队列研究，研究对象为北京市昌平区北七家社区卫生服务中心辖区内40岁以上常住居民中的高血压患者。2015—2016年完成首次人口学、既往病史、实验室检查、认知功能评价（采用MoCA评估）等信息采集。随访7～8年，于2023年随访认知功能，以△MoCA（基线MoCA评分－随访MoCA评分）评估研究对象的认知功能下降情况。采用多因素线性回归探讨TG水平对认知功能下降的影响。 结果 研究共纳入338例患者，平均年龄为（59.1±6.8）岁，男性111例（32.8%）。TG水平与认知功能下降（△MoCA）呈正相关（β=0.172，P=0.025），且主要与视空间执行功能下降相关（β=0.152，P=0.045）。 结论 社区高血压患者TG水平升高与认知功能下降独立相关，且可能主要影响视空间执行功能。 Abstract: Objective To investigate the effects of TG levels on cognitive function in community patients with hypertension. Methods This study was a prospective cohort study based on community population. The subjects were hypertensive over 40 years old in Beiqijia Community Health Service Center, Changping District, Beijing. The first collection of information on demographics, medical history, laboratory tests, and assessment of cognitive function (using the MoCA) was completed from 2015 to 2016. Cognitive function was reassessed in 2023 after a follow-up of 7-8 years. Cognitive decline was defined as ΔMoCA (baseline MoCA score－follow-up MoCA score). Multivariate linear regression was used to analyze the effects of TG levels on cognitive decline. Results A total of 338 patients [mean age (59.1±6.8) years, 111(32.8%) males] were included. TG levels were positively correlated with cognitive decline (ΔMoCA) (β=0.172, P=0.025), and were mainly correlated with the decline of visuospatial executive function (β=0.152, P=0.045). Conclusions There is an independent correlation between the increased TG level and the decreased cognitive function in community patients with hypertension, and it may primarily affect the visuospatial executive function.

摘要： 目的 探讨对神经内科研究生应用高压氧科混合式教学模式的效果。 方法 纳入2023年4—12月在高压氧科实习的神经内科研究生为研究对象。授课前发放调查问卷摸底研究生基础情况和需求后，应用混合式教学模式向研究生讲授高压氧理论知识和实际操作（共40学时），授课后根据出科考试和问卷调查评估教学效果。 结果 研究共纳入15名神经内科研究生，前期调查问卷显示，13名（86.67%）神经内科研究生希望将高压氧作为选修课程。采用混合式模式教学后，15名神经内科研究生均通过出科考试，出科考试成绩为（93.53±3.14）分。神经内科研究生对高压氧定义和作用机制的知晓率从授课前的40.00%（6例）提升至100%（15例）（P=0.0003）；对高压氧治疗适应证和禁忌证的知晓率从授课前的33.33%（5例）提升至93.33%（14例）（P=0.0008）；教学后，研究生对高压氧治疗方案的知晓率为80.00%（12例）。神经内科研究生对教学的满意度为100%（15例）。 结论 混合式教学模式可提升高压氧教学水平，使神经内科研究生有效掌握高压氧学科知识，教学效果显著。 Abstract: Objective To explore the effect of blending learning model in training teaching of hyperbaric oxygen (HBO) for postgraduates majoring in neurology. Methods Postgraduates who major in neurology and work as interns in the Department of HBO from April to December 2023 were enrolled in this study. After sending out questionnaires to investigate the basic situation and needs of postgraduates, the blending learning model was applied to teach theoretical knowledge and practical operations of HBO, and the total credit hours were 40. Exams and questionnaires were used to evaluate the teaching effect. Results A total of 15 neurology postgraduates were included in the study. According to the questionnaire, 13 (86.67%) neurology postgraduates hoped to take HBO as an elective course. After adopting the blending learning model, all 15 neurology postgraduates passed the exam, and the score was (93.53±3.14) points. During the course, the awareness rates of HBO definition and mechanism in these postgraduates increased from 40.00% (6 cases) to 100% (15 cases) (P=0.0003), and the awareness rates of HBO indications and contraindications increased from 33.33% (5 cases) to 93.33% (14 cases) (P=0.0003). Besides, 12 postgraduates (80%) were aware of HBO treatment regimens. The satisfaction rating of these postgraduates was 100% (15 cases). Conclusions Blending learning model can effectively enhance the teaching level of HBO, and enable the postgraduates who major in neurology to master the knowledge of HBO more effectively.

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The circulation of data factor is the key to the development of the digital economy, and security first is the principle of building data factor market. This paper focuses on the civil aviation field, and describes the current data resource characteristics and circulation status, as well as the security challenges faced by multi-subject participation. A three-layer model is proposed, which is based on intra-enterprise data governance, intra-industry data circulation and crossindustry data circulation. Taking the data governance practice of Travelsky Technology Limited as an example, this paper introduces data architecture governance, data standard implementation, classification and full life cycle security protection. Finally, data factor circulation and security governance in civil aviation field are prospected. [ABSTRACT FROM AUTHOR]

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[Objective]To understand the structural characteristics of the plankton community and its key environmental impact factors in the rivers of Muli mining area, and to provide data support and reference basis for the management and protection of water resources in the mining area. [Method]Collection and analysis of water and plankton in the rivers (Duosuo and Mori) that surround the opencast mine in the town of Muli. [Result]6 Phylum (21 species) of phytoplankton and 2 Phylum (15 species) of zooplankton were collected in the Dosuo River and 6 Phylum (19 species) of phytoplankton and 2 Phylum (9 species) of zooplankton were collected in the Mori River. In both rivers diatoms, green algae and protozoa were the dominant species, and the density and biomass of plankton were quantitatively higher upstream and lower downstream. The Shannon-Wiener, Margalef and Pielou indices for phytoplankton and zooplankton in Duosuo River are 1. 64 and 0. 58, 0. 86 and 0. 33, 0. 69 and 0. 42, respectively;the Shannon-Wiener, Margalef and Pielou indices for phytoplankton and zooplankton in Mori River are 1. 86 and 0. 21, 0. 87 and 0. 24, 0. 79 and 0. 36. Water temperature, pH, and nitrogen nutrients were identified as the main environmental factors affecting the structure of the planktonic communities in the Dosso and Mojito Rivers by redundancy analysis (RDA) and correlation analysis. [Conclusion]The ecological protection of water in the Muli mining area should focus on nutrient pollution and strengthen the control of non-point source pollution caused by overgrazing. [ABSTRACT FROM AUTHOR]

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