Search

基于SC-FDE（单载波频域均衡）和OFDM（正交频分复用）的60GHz通信系统,对联合信道估计的IQ不平衡补偿算法进行了研究。通过最小化CRE（信道残余能量）,在未知IQ不平衡参数时可得CIR（信道冲击响应）的最优解。一旦得到IQ不平衡参数,CIR的估计可以通过简单的替换计算来获得。因此,该算法可将信道与IQ不平衡分离开来进行灵活的补偿,且对训练序列没有任何限制。仿真结果表明,无论是60GHz LOS（视距）还是NLOS（非视距）信道,使用该方法均可得到很好的性能。

Er3+:Yb3+共掺磷酸盐玻璃激光器能发射1.54μm附近的激光,这种激光器广泛应用于光通信、激光雷达和人眼安全激光测距等方面。文章以输出波长为975nm的半导体激光器为泵浦源,采用Er3+:Yb3+共掺磷酸盐玻璃为工作物质,成功地实现了平平腔、平凹腔常温下连续输出TEM00模的1.54μm激光。实验结果表明:随着谐振腔腔长的增加,输出激光能量减小,而阈值功率增大。最后采用弯月型输出镜改善光束质量,获得了最大功率为30mW的1.54μm信号光输出。

This paper observed the effect of cupping therapy in the treatment of uterine prolapse complicated with stress urinary incontinence (SUI), and summarized related nursing measures. Based on the evaluation of uterine prolapsed symptom, degree of SUI and pelvic floor muscle strength, the Traditional Chinese Medicine nursing technique cupping therapy, in combination with routine care, nutrition support and psychological care, was carried out. . The cupping therapy is considered as an easy-to-operate, noninvasive, painless technique, which can effective reduce the pain degree and improve the patient quality of life. (本文观察拔罐法治疗1例子宫脱垂合并压力性尿失禁患者的效果, 总结相关护理经验。在完善子宫脱垂症状、压力性尿失禁分度测定和盆底肌力评估的基础上, 实施中医特色护理技术拔罐法, 治疗期间配合常规护理、饮食护理和心理指导。拔罐法操作简单, 无创无痛, 能减轻患者痛苦, 提高生活质量。)

The Department of Gynecology of Dongfang Hospital of Chinese Medicine has established a gynecology Traditional Chinese Medicine nursing specialist clinic, carried out a variety of TCM characteristic nursing projects, integrated the concept of medical and nursing integration into the construction of gynecology TCM nursing specialist clinic, and formed a gynecology integrated medical care model with TCM characteristics. The nursing clinic formulates the nursing plan and health education plan from three aspects: prevention before disease, prevention after disease and recovery after disease. On the basis of doctors’ physique identification, the external treatment methods of traditional Chinese medicine represented by ear point treatment and acupoint application are comprehensively applied to help patients recover their health as soon as possible, so as to promote the development of traditional Chinese medicine nursing, improve the ability of TCM nursing service and highlight the characteristics of TCM. (妇科中医护理专科门诊, 是将医护一体化理念融入到妇科中医护理专科门诊的建设中, 开展多种中医特色护理项目, 形成具有中医特色的妇科整体化医护模式。护理门诊从“未病先防, 已病防变, 病后防复”三方面制定护理方案及健康教育计划, 在医师体质辨识的基础上, 综合应用以耳穴治疗、穴位贴敷为代表的中医外治手法, 帮助患者尽快恢复健康, 以推动中医护理事业的发展, 提升中医护理服务能力, 彰显中医特色。)

In order to explore the composition and differences of intestinal microbiota in healthy and diarrhea weaned piglets, a total of 10 fecal samples were collected from 7-day-old weaned piglets, 5 samples from healthy piglets (JK group) and 5 samples from diarrhea piglets (FX group) in this experiment. 16S rRNA was used to analyze the diversity, composition and species differences of intestinal flora. The results were as follows: compared with the JK group, the diversity of the FX group was not significant (P>0.05), and the richness was significantly lower (P<0.05), the β diversity revealed certain similarities and differences in the composition of microbial communities between the two groups of weaned piglets. Firmicutes and Bacteroidetes were the main dominant phyla in the two groups, while compared with the JK group, the relative abundance was significantly higher in the FX group (P<0.05). Oscillospiraceae, Methanobacteriaceae, Bacteroidaceae, Lactobacillaceae and Lachnospiraceae were the main dominant families in the two groups. Compared with the JK group, the relative abundance of Enterobacteriaceae and Desulfovibrionaceae in the FX group increased significantly, but the relative abundance of Ruminococcaceae, Veillonellaceae and Selenomonadaceae decreased significantly (P<0.05). Bacteroides and Lactobacillus were the main dominant genera in both groups. Compared with the JK group, the relative abundance of Lachnoclostridium, Escherichia-Shigella, Intestinimonas, and Parabacteroides in the FX group increased significantly(P<0.05), while the relative abundance of Treponema decreased significantly (P<0.05), and the relative abundance of Megasphaera was extremely significantly decreased (P<0.01). In conclusion, it is concluded that there are certain similarities and differences in the structure and composition of fecal microbiota in the JK and FX groups of weaned piglets. The abundance of Firmicutes and Proteobacteria (E. coli-Shigella) increase in FX group, which cause the imbalance of the faecal flora. [ABSTRACT FROM AUTHOR]

【Objective】To study the effects of combined application of zinc and selenium on the accumulation and transport of mercury in rice in a soil-rice system, and to investigate the barrier effect of combined zinc and selenium application on mercury in rice, and provide a reference for the safe utilization of mercury-contaminated soil.【Method】Selecting mercury-contaminated soil in the mining area of Bijiang District, Tongren, Guizhou, having the rice variety Chuankangyou 727 as the research subject, and using pot experiment, we measured the growth and development characteristics of the rice plant, as well as the available mercury in the soil and the mercury content in various organs of rice. 【Result】The simultaneous application of zinc and selenium reduced the available mercury content in the soil by 45% to 75.2%. Alternatively, when low concentrations of selenium and zinc were applied together, the available mercury content in the soil reduced by 75.2%. The application of zinc and selenium in combination resulted in a reduction of mercury levels in different organs of rice plant by 15.2% to 92.3%. The most effective reduction effect was in the mercury content of the grain, with a decrease of 87.6% to 92.3%. Except for the high concentration of selenium and the combination of high and low concentrations of zinc, which promoted the transportation of mercury from the roots to the grains in rice plant, the blocking effect of a zinc-selenium combination on the accumulation and transportation of mercury in the rice plant was better than that of zinc or selenium applied individually. The combination of zinc and selenium reduced the enrichment coefficient of mercury from roots to grains in rice by 88% to 92%. Similarly, when low concentration selenium was combined with both high and low concentrations of zinc, the transportation coefficient of mercury from the roots to the grains in rice plant reduced by 69.2% and 61.5% respectively.【Conclusion】The combined application of zinc and selenium has a significant blocking effect on mercury in rice, effectively alleviating the toxic effects of mercury on rice growth and development. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Immunology is the property of Medical Periodical Society of Jilin and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To address the issue of resource wastage and increasing latencies in the placement process of edge servers, this paper analyzed and modeled the user density and average access time of edge server placement schemes as multi-objective optimization problems. It designed an edge server placement scheme based on user density and average access time, and proposed a multi-objective sea-horse genetic algorithm (MOSGA) to solve this problem. The MOSGA algorithm firstly used the idea of multi-objective optimization algorithm to improve the SHO algorithm, so that the SHO algorithm could be applied to multi-objective optimization problems. It used the genetic algorithm to improve the propagation operation of the SHO algorithm, so that the MOSGA could better jump out of the local optimal solution and accelerate the solution of the problem. The proposed algorithm was verified on the data set of Shanghai Telecom, and the simulation experiment results show that MOSGA is obviously better than RA, K-means, NSGA and LMM, which not only effectively solves the problem of server resource waste, but also greatly reduces the time of terminal equipment to access the server. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

因應 12 年國教強調探究與實作的改革，本研究以「昆蟲生理學特論」課程培育 14 位國 小自然科教師兩種探究式教學法，探討其學習成效與抉擇應用的考量。本研究培育內容 包含：講授昆蟲學理論、探究式教學法理論、示範教學，以及國小自然科教師抉擇一種 教學法設計實驗教案與微型教學，並設計戶外教學學習單；本研究使用 PO+E 微型教學 評量或 POEST 微型教學評量予以評量，並訪談他們抉擇應用探究式教學法的想法。結果 顯示：一、四組使用 PO+E 教學法微型教學，三組使用 POEST 教學法微型教學，評量達到優良等級，表示能掌握探究式教學法的精髓。二、自然科教師學習探究式教學法後，所設計的教案能先鋪陳教學情境，使用簡報建構基本知識後再讓學生預測；其次、設計的實驗包含探究與實作，讓學生根據實驗紀錄去修正預測的錯誤理由。三、自然科教師 抉擇 PO+E 教學法是因為「科學解釋能力」六格容易撰寫，探討「科學原理」使得科學實驗更有意義。四、自然科教師抉擇 POEST 教學法是因為能引導學生使用 2 個實驗證據證明自己的主張，避免淪為主觀。 In response to Taiwan’s 12-year Basic Education plan, which emphasizes the reform of inquiry and implementation, this study used an "Advanced Entomology Physiology" course to train 14 primary science teachers to study two methods of inquiry teaching, where the teachers observed the learning effectiveness of the two methods, and selected the application they felt met their teaching needs. The nurturing contents included: teaching the theory of entomology and two inquiry-based teaching methods, as well as demonstration teaching, then the primary science teachers selected their preferred teaching method to design teaching and micro-teaching plans. This study used the Micro Teaching Assessment of PO+E (MTAP) and the Teaching Assessment of PO+E, as well as scientific explanations with text scaffolding (MTAPS), to evaluate the micro-teaching plans, and interviewed the participants regarding their thoughts. The results, are as follows. First, four groups selected the PO+E teaching method for micro-teaching, while three groups selected the POEST teaching method for micro-teaching. The assessment results achieved the excellent level, indicating that they could master the inquiry teaching methods. Second, after learning the two inquiry teaching methods, the primary science teachers first arranged their teaching situations and constructed lessons regarding the basic required knowledge, and then encouraged the students to predict the outcomes. The teachers found that they could design inquiry guidelines, as implement experiments, and remind students to correct the wrong reasons for their predictions, as based on the experimental records. Third, some primary science teachers selected the PO+E teaching method because the "science interpretation ability" made it easy to write lesson plans, and the exploration of "scientific theory" in class made the scientific experiments more meaningful. Fourth, primary science teachers selected the POEST teaching method because they could guide lines for students to apply 2 experimental evidence methods to prove their claims and avoid becoming subjective.

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aiming at the problems of long computation time, error-prone results, and difficulty in verification associated with the traditional determinant feedback loop calculation method in system dynamics, a rapid calculation method for system dynamics feedback loops was proposed.This method utilizes the Loops function of Vensim software, the feedback loop set of the system was generated by taking each level bit variable as the starting point, followed by the removal of duplicate feedback loops to obtain a set of all non-repetitive feedback loops in the system. Taking the "Base+Farmers" supply chain complex system of Mingxin Farm in Pingxiang as an example, 11 strongly simplified flow rate basic in-tree models that have been constructed, and both the determinant calculation method and this new method were used to compute all feedback loops in the system.The research showed that both methods yielded the same results, but the fast calculation method of the feedback loop significantly reduced the calculation time and improved the calculation accuracy.Based on this, the system structure can be deeply analyzed to put forward corresponding management countermeasures. [ABSTRACT FROM AUTHOR]

Copyright of Journal on Communication / Tongxin Xuebao is the property of Journal on Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Low-Carbon Chemistry & Chemical Engineering is the property of Low-Carbon Chemistry & Chemical Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Occupational Health & Emergency Rescue is the property of Occupational Health & Emergency Rescue Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Frontiers of Computer Science & Technology is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

肾脏是体内具有高代谢率的器官之一，能量代谢是维持肾单位不同细胞结构和功能的基础。应激环境中 近端小管上皮细胞更容易发生代谢重编程，由于缺氧、线粒体功能障碍和营养感知通路紊乱，肾小管上皮细胞的代 谢过程从脂肪酸β氧化（FAO）转变为糖酵解。尽管糖酵解增强可弥补能量消耗，但持续的FAO受抑和糖酵解增强 可引起炎症、脂质堆积和纤维化。早期改善线粒体功能和恢复FAO对于延缓慢性肾脏病进展有重要价值。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Frontiers of Computer Science & Technology is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Vibration, Measurement & Diagnosis is the property of Nanjing Hangkong Daxue and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Drive is the property of Electric Drive Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hubei Open Vocational College is the property of Journal of Hubei Open Vocational College Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Objectives]This study aimed to investigate the effect of adding broad bean skin(BBS)to the diet on the barrier-related gene expression, digestive enzyme activity and microflora of the jejunum in Hu sheep. [Methods]Thirty 4-month-old male Hu sheep with similar body weight[(27±2.0)kg]were divided into two groups, feeding with basal diet(CON)and diet with 30% broad bean skin(BBS), respectively. The pre-feeding period was 10 days, and the formal period was 50 days. At the end of the experiment, jejunal tissue and chyme were collected(n=5), mucosal barrier-related gene expressions were detected by RT-qPCR, mucosal digestive enzyme activities were detected by biochemical kits, and chyme microbial was analyzed by high-throughput sequencing. [Results]Compared with CON group, the jejunal mucosal cell junction genes Claudin-1, Occludin, MUC-2 and ZO-1, pro-inflammatory factors IL-6, IL-10 and TNF-α mRNA levels in the BBS group had no significant changes(P>0.05), while the expression level of IL-1β mRNA significantly decreased(P<0.05). There was no significant change in the mucosal α-amylase, trypsin and lipase activities between two groups(P>0.05). The microbial Shannon index, Chao1 index and Observed_otus index in the BBS group significantly decreased(P<0.05). At the phylum level, the relative abundance of Proteobacteria in the BBS group significantly increased(P<0.05), while the relative abundance of Firmicutes, Patescibacteria and F/B value significantly decreased(P<0.05). At the genus level, the relative abundance of Christensenellaceae_R-7_group, Firmicutes_unclassified, Candidatus_Saccharimonas, Saccharofermentans, Lachnospiraceae_NK3A20_group and Acetitomaculum significantly decreased(P<0.05). The functions of jejunal microbial differential flora were mainly enriched in the tricarboxylic acid cycle, fatty acid β-oxidation, protocatechuic acid degradation and L-leucine degradation pathways. [Conclusions]The addition of 30% BBS in the diet can decrease the jejunum mucosal inflammatory factor IL-1β mRNA expression level, change the jejunum chyme microbial flora diversity and relative abundance, and regulate intestinal fermentation environment. The results will provide a reference for the application of broad bean skin in the development of sheep industry. [ABSTRACT FROM AUTHOR]

Copyright of Research of Soil & Water Conservation is the property of Institute of Soil & Water Conservation, Chinese Academy of Sciences & Ministry of Water Resources and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Ocean University is the property of Editorial Department of Journal of Shanghai Ocean University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The cholinergic anti-inflammatory pathway is widely involved in the development of rheumatoid arthritis. However, the immunoregulatory mechanism of choline acetyltransferase (ChAT)/α7 nicotinic acetylcholine receptor (α7nAChR)/nuclear factor (NF)-κB signaling pathway in the pathogenesis of rheumatoid arthritis has not been reported. OBJECTIVE: To investigate the immunoregulatory mechanism of ChAT/α7nAChR/NF-κB signaling pathway in the pathogenesis of rheumatoid arthritis. METHODS: Thirty-two female Wistar rats were randomly divided into healthy control group, arthritis model group, vagotomy group and sham operation group, with eight rats in each group. Except for the healthy control group, other groups were treated with bovine type-all collagen and Freund’s complete/incomplete adjuvant to construct the rat arthritis model. After successful molding, the vagus nerve was severed from the left vagus nerve in the neck in the vagotomy group, while only the vagus nerve was isolated in the sham operation group. At 5 weeks after surgery, the body mass, arthritis score, joint swelling degree, pathological changes of the spleen and joint were detected. The levels of interleukin-1, interleukin-6 and tumor necrosis factor-α in serum were detected by ELISA. The mRNA and protein expression levels of ChAT/α7nAChR/NF-κB pathway core genes were detected by qRT-PCR and western blot, respectively, and analyzed by immunohistochemistry. RESULTS AND CONCLUSION: Compared with the healthy control group, the body mass of rats in the arthritis model group was significantly decreased (P < 0.05), the arthritis score was significantly increased (P < 0.01), the ankle swelling degree was aggravated, the joint space was reduced with inflammatory cell infiltration, and the white pulp and germinal center of the spleen were enlarged and increased. Moreover, the levels of interleukin-1, interleukin-6 and tumor necrosis factor-α were significantly increased, and the mRNA and protein expressions of α7nAChR, ChAT, IκBα, and NF-κBp50/p65 on the joint surface were also significantly increased in the arthritis model group compared with the healthy control group (P < 0.05, P < 0.01). Compared with the arthritis model group and the sham operation group, the body mass of rats in the vagotomy group was significantly decreased (P < 0.05), the arthritis score was significantly increased (P < 0.05, P < 0.01), the swelling degree of the ankle joint was aggravated with deformity, the joint space disappeared with inflammatory cell infiltration, the white pulp and germinal center of the spleen were enlarged and merged. Compared with the arthritis model group and the sham operation group, the levels of interleukin-1, interleukin-6 and tumor necrosis factor-α were significantly increased in the vagotomy group (P < 0.05, P < 0.01), as well as the mRNA and protein expressions of α7nAChR, ChAT, IκBα, and NF-κBp50/p65 were significantly increased on the joint surface (P < 0.05, P < 0.01). To conclude, the vagus nerve regulates the cholinergic anti-inflammatory pathway and stimulates the ChAT/α7nAChR/NF-κB signaling pathway to participate in the disease progression of rheumatoid arthritis. It indicates that the cholinergic anti-inflammatory pathway may be a potential target for the treatment of rheumatoid arthritis. [ABSTRACT FROM AUTHOR]

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Tropical Medicine is the property of China Tropical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)