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Copyright of Wool Textile Journal is the property of National Wool Textile Science & Technology Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the potential mechanism of Viticis Fructus in the treatment of liver cancer. Methods The effective components of Viticis Fructus were determined and the corresponding targets were screened through the traditional chinese medicine systems pharmacology database and analysis platform. The related targets of liver cancer were obtained by GeneCards database,and the potential targets of the anti-liver cancer effect of Viticis Fructus were determined. Meanwhile,a drug-disease-active ingredient-target network was constructed. The target protein interaction network was constructed based on the STRING platform, and the related core targets were obtained by the R language. The Go function and KEGG signal pathway enrichment analysis of target genes were analyzed by the DAVID database. Results 27 active ingredients with therapeutic effects on liver cancer were screened from Viticis Fructus,which acted on 88 targets. Quercetin and Kaempferol were the main active components of Viticis Fructus,and their target mainly involved NCOA2,NCOA1,PGR,etc. Viticis Fructus mainly involved biological processes such as the positive regulation of RNA polymerase Ⅱ promoter transcription,cell reaction to hydrogen peroxide,etc. Viticis Fructus playeds a role in the treatment of liver cancer by regulating tumor necrosis factor,P53 and other signaling pathways. Conclusion Viticis Fructus has the characteristics of multi-component,multi-target and multi-channel in the treatment of liver cancer. [ABSTRACT FROM AUTHOR]

Copyright of China Surfactant Detergent & Cosmetics is the property of China Surfactant Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Materials / Gongneng Cailiao is the property of Chongqing Functional Materials Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Materials / Gongneng Cailiao is the property of Chongqing Functional Materials Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Materials / Gongneng Cailiao is the property of Chongqing Functional Materials Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)