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Copyright of Application Research of Computers / Jisuanji Yingyong Yanjiu is the property of Application Research of Computers Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the risk factors for re-fracture after percutaneous kyphoplasty (PKP) in patients with osteoporotic vertebral compression fractures (OVCF) ，and to evaluate the value of bone mineral density (BMD) as a prognostic indicator for re-fracture． Methods A prospective cohort study including 208 patients，who had osteoporotic vertebral compression fractures and had PKP performed in our hospital． BMD was measured and other general clinical data were also collected and analyzed． All patients were followed up for more than 2 years． The occurrence of re-fracture or death was defined as the end-point event． Kaplan-Meier analysis and multivariate Cox regression model were used for the analysis of risk factors． Receiver operating characteristic curve (ROC curve) was used to evaluate the predictive value of BMD． Ｒesults Among all the 208 patients，37 (17. 8%) were re-fractured in 2 years． Cox regression analysis showed that BMD，gender，and initial double segment fractures were independent and important predictors for re-fracture． Using BMD as a forecast standard，the ＲOC area under the curve (AUC) was 0. 787，and diagnose critical point was － 3. 0SD． The sensitivity and specificity were 83. 2% and 66. 8%，respectively． Kaplan-Meier analysis revealed that patients with BMD-T level ≤ － 3. 0SD had a higher re-fracture rate than patients with BMD-T level ＞ － 3. 0SD． Conclusion BMD level was an effective and suitable predictor for re-fracture in patients with OVCF after PKP， and the high risk of re-fracture after PKP should be considered especially when patients' BMD-T level ≤ － 3. 0SD． [ABSTRACT FROM AUTHOR]