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Objective To understand the psychological status among nurses during the closed-off management for prevention and control of COVID-19, and provide references for improving quality of management in hemodialysis center during the period of closed-off management. Methods Semi-structure interview were carried out among nurses from a certain hospital of Shanghai which conducted the closed-off management for prevention and control of COVID-19. The date were analyzed by thematic analysis method and then extracted the themes. Results Two themes were extracted: thought transformation and fluctuation of emotion, coping style. Conclusion Nurses are vulnerable to developing negative emotions when facing the epidemic situation. Efforts should be made to improve coping mechanisms, provide emotional guidance and build nurses’ confidence in overcoming the epidemic. (目的 了解新型冠状病毒肺炎疫情防控医院闭环管理期间血透室护理人员的心理状态, 为进一步完善闭环管理期间血透室管理模式提供参考意见。方法 对上海市某一所因新型冠状病毒肺炎疫情防控采取闭环管理医院的血透室护理人员进行半结构式访谈, 采用主题分析法对资料进行整理分析, 生成主题。结果 最终析出主题两个: 思想情绪波动及应对方式。结论 面对疫情, 护理人员易产生多种负面情绪。因此, 护理人员及管理者应完善应对机制, 做好情绪疏导, 树立战胜疫情的信心。)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University Chemistry is the property of Peking University, College of Chemistry & Molecular Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 观察阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的血液学参数变化，分析其与患者并发缺 血性脑卒中的相关性。方法 有打鼾或日间过度嗜睡的神经内科住院患者 237 例，根据呼吸暂停低通气指数 （AHI）进行分组，AHI<5 次/小时为对照组（40 例）、5 ~ <15 次/小时为轻度组（62 例）、15 ~ <30 次/小时为中度组 （65 例）、≥30 次/小时为重度组（69 例）。比较各组基本资料、睡眠呼吸指标监测结果［AHI、夜间平均血氧饱和度 （Mean SpO2 ）、夜间最低血氧饱和度（Min SpO2 ）］、血液学参数检测结果［RBC、Hb、红细胞容积（Hct）、红细胞分布宽 度（RDW）、PLT、平均血小板体积（MPV）、血小板分布宽度（PDW）］，分析血液学参数与睡眠监测指标的相关性，分 析 OSAHS并发缺血性卒中的影响因素。结果 轻度组、中度组、重度组TC水平高于对照组，重度组 BMI高于对照 组，中度组、重度组 RBC 高于对照组，中度组 RBC 高于轻度组，中度组 Hb 高于轻度组和对照组（P 均<0. 05）。重 度组 Mean SpO2低于对照组、轻度组、中度组，轻、中、重度组 Min SpO2低于对照组，重度组 Min SpO2低于轻、中度组 （P 均<0. 05）。所有患者 RBC、Hb、Hct与 AHI呈正相关（r分别为 0. 179、0. 161、0. 151，P 均<0. 05），PLT 与 Min SpO2 呈负相关（r=-0. 174，P<0. 05）。重度组 PLT 与 Min SpO2呈负相关、而 MPV 与 Min SpO2呈正相关（r 分别为-0. 346、 0. 411，P 均<0. 05）。Logistic 回归分析结果显示，年龄、性别、TC、AHI 是 OSAHS 患者并发脑卒中的影响因素。 结论 OSAHS患者RBC、Hb水平增加，部分血液学参数（RBC、Hb、Hct、PLT、MPV）与睡眠呼吸指标（AHI、Min SpO2 ） 存在一定相关性。OSAHS患者的血液学参数变化与患者并发缺血性脑卒中无明显关联。 [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effects of sKlotho on the proliferation and differentiation of osteoblasts in mice under high glucose. Methods The routine cultured osteoblasts (MC3T3-E1 cells) were randomly divided into four groups: high glucose group (35 mmol/L glucose), high glucose +0.01 μg/mL sKlotho group (35 mmol/L glucose +0.01 μg/mL sKlotho), high glucose +0.02 μg/mL sKlotho group (35 mmol/L glucose +0.02 μg/mL sKlotho), and high glucose + 0.2 μg/mL sKlotho group (35 mmol/L glucose +0.2 μg/mL sKlotho). CCK-8 was used to detect the proliferation ability of MC3T3-E1, and Western blotting was used to detect the expression levels of Runx2, OC, and ALP. Results After intervention for 72 h, with the increasing concentrations of sKlotho, the Of) value increased, with the highest in the high glucose and 0.2 μg/mL sKlotho group, and significant difference was found between the high glucose group and high glucose and 0.2 μg/mL sKlotho group (all P <0.05 ). As the concentration of sKlotho increased, the expression of Runx2 protein, OC protein and ALP protein increased gradually, with the highest in the high glucose +0.2 μg/mL sKlotho group, and significant difference was found between the high glucose group and high glucose and 0.2 μg/mL sKlotho group (all P < 0.05). Conclusion The sKlotho can improve the proliferation and differentiation of MC3T3-E1 in mice under high glucose in a concentration-dependent manner. [ABSTRACT FROM AUTHOR]