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Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the inhibitory effect of inhibition of antigen presentation attenuators( iAPA)- based dendritic cells( DC) and cytotoxic T lymphocytes( CTL)( iAPA- DC/CTL) on HepG2 xenograft in nude mice. Methods Human hepatocarcinoma HepG2 cells were subcutaneously implanted into nude mice on nude mice to establish a HepG2 xenograft model transplanted tumor model of human HCC. Twelve nude mice were randomly and equally divided into two groups: normal saline control group( C group) and iAPA- DC /CTL group( DC group). After four times of treatment with iAPA- DC /CTL( once a week),all mice were sacrificed. Tumor growth was evaluated by measuring the long and short diameters and delineating the tumor growth curve. The tumors were weighed,and the tumor inhibition rate was calculated. In addition,histopathological examination was performed. Comparison of means between the two groups was made by independent- samples t test. Results The HepG2 xenograft model was successfully established in 92. 31% of all mice. The tumor volume was 697. 69 ± 143. 99 mm3 in C group and 485. 64 ± 188. 75 mm3 in DC group; the tumor growth was significantly slower in DC group than in C group( t = 2. 28,P < 0. 05). The tumor weight was 0. 32 ± 0. 07 g in C group and 0. 22 ± 0. 08 g in DC group; DC group had a significantly lower tumor weight than C group( t = 2. 31,P < 0. 05),and the tumor inhibition rate was 30. 39%. After immunohistochemical staining,T lymphocyte count was 0 cell /high- power field( HPF) in C group and 39. 74 ± 5. 11 cells /HPF in DC group; the number of T lymphocytes in DC group was significantly higher than that in C group( t = 19. 05,P < 0. 05). Conclusion iAPA- DC /CTL can effectively inhibit the growth of subcutaneous HepG2 xenograft in nude mice. [ABSTRACT FROM AUTHOR]

目的:在外科见习中应用病区轮转的多病种全病程临床见习教学模式，以探索临床见习新模式。方法于2014年9月至2015年9月将2012级在校2个班级的临床专业本科学生分为研究组和对照组，每组90人。研究组实施基于病区轮转的多病种全病程临床见习教学模式，对照组实施传统见习教学模式。学年结束后比较两组学生理论知识和临床实践技能操作考试成绩方面的差异。结果研究组学生理论知识和临床实践技能操作考试成绩[分别为（71.51±8.03）、（76.42±6.72）分]均明显优于对照组[分别为（67.70±7.25）、（71.89±8.12）分]，差异均有统计学意义（P<0.05）。结论基于病区轮转的多病种全病程临床见习教学模式遵循了临床见习教学规律，规范带教过程，提高带教艺术；有利于学生临床思维能力和沟通交流能力的培养；且有利于教学相长，是一项有效的见习教学改革模式。 [ABSTRACT FROM AUTHOR]