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Copyright of Nonferrous Metals (Extractive Metallurgy) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The relationship between inflammatory response and tumor has gained great attention in recent years. Tumor - associated macrophages (TAMs) play an important role in tumor growth, proliferation, metabolism, and metastasis. Many studies have confirmed that most TAMs have an M2 phenotype and can promote tumor growth, metabolism, metastasis, and angiogenesis in primary liver cancer. The transformation of M2 macrophages into Ml macrophages changes the biological manifestations of hepatoma cells, which may become a new therapeutic strategy for liver cancer. This article reviews the research advances in the association between TAMs and the progression of primary liver cancer, as well as possible therapeutic regimens. [ABSTRACT FROM AUTHOR]