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The clinical features and electromyography features of anal sphincter in patients with multiple system atrophy were analyzed, and the value of electromyography of anal sphincter in early diagnosis of multiple system atrophy was discussed. A retrospective analysis was conducted on 26 patients with complete information who were hospitalized for multiple system atrophy from January 2019 to July 2022 at the Aerospace Center Hospital. The patients general information, activities of daily living score, and external anal sphincter electromyography results were collected. The patients were grouped based on whether there were satellite potential, urinary and bowel disorders, or orthostatic hypotension, and the age, duration of disease, activities of daily living score, and external anal sphincter electromyography results were compared between the groups. The correlation between the motor unit potentials average duration of external anal sphincter electromyography, disease duration, and activities of daily living score were analyzed. The most common symptoms in 26 multiple system atrophy patients are urinary and bowel disorders, gait disturbance, and sleep disorders, while the most common signs are muscle tension disorders, orthostatic hypotension, and ataxia. The mean duration of motor unit action potential in 26 patients is 11. 6 ms (range 10. 1 ms to 14. 5 ms), the mean amplitude is 876. 5 μV (range 740. 8 μV to 1 135. 8 μV), and the percentage of multiphase wave is 27. 4% (range 13. 3% to 53. 6% ). The group with satellite potential has a longer average duration, a higher percentage of multiphasic waves, and lower activities of daily living scores (P < 0. 05). The group with orthostatic hypotension has lower activities of daily living scores (P < 0. 05). The disease duration of multiple system atrophy patients is significantly negatively correlated with activities of daily living scores (r = - 0. 695, P = 0. 000), while there is no significant correlation between disease duration and the average duration of motor unit potentials, or between activities of daily living score and the average duration of motor unit potentials. The longer the disease duration in multiple system atrophy patients, the more severe the disease becomes. Patients with satellite potential or orthostatic hypotension have more severe disease conditions. External anal sphincter electromyography is advantageous in the early diagnosis of multiple system atrophy patients without urinary and bowel disorders. [ABSTRACT FROM AUTHOR]

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the clinical effect of Traditional Chinese Medicine collapse stains combined with wax therapy in the treatment of urinary dysfunction in patients with multiple system atrophy. Methods A total of 30 patients with multiple system atrophy accompanied by urinary dysfunction were divided into observation group and control group according to the time sequence of hospital admission, with 15 cases in each group. The control group received routine treatment and nursing, and the observation group was treated with Traditional Chinese Medicine collapse stains combined with wax therapy based on the control group. The therapeutic effect of the two groups was compared by using Overactive Bladder Symptom Score (OABSS). Results The total score of OABSS was decreased in both two group after treatment, and OABSS score in the observation group was lower than that in the control group(P＜0. 05). Conclusion Traditional Chinese Medicine collapse stains combined with wax therapy can effectively relieve urinary dysfunction and improve the quality of life of the patient with multiple system atrophy, and it is worth promoting. (目的 探讨中药塌渍联合蜡疗治疗多系统萎缩患者排尿障碍的效果, 总结护理体会。方法 选取2023年1月—8月科室收治的30例多系统萎缩伴排尿障碍患者为研究对象, 根据入院时间顺序分为观察组和对照组, 各15例。对照组给予常规治疗及护理, 观察组在对照组的基础上增加中药塌渍联合蜡疗治疗。采用膀胱过度活动症状评分(OABSS)进行疗效评估。结果 治疗后两组患者OABSS总分较治疗前降低(P＜0. 05), 且观察组OABSS总分低于对照组(P＜0. 05)。结论 中药塌渍联合蜡疗可进一步改善多系统萎缩患者排尿障碍, 有助于提升患者的生活质量。)

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the relevant factors on the prognosis of patients with multiple system atrophy (MSA). Methods: The clinical data of 85 clinically diagnosed MSA patients admitted to the Department of Neurology, First Affiliated Hospital of Air Force Military Medical University was collected from January 2016 to January 2019. These MSA patients were followed up every 6 months until they needed aid to walk. The study time limit is 3.5 years. 10 factors that may affect independent walking of MSA patients were screened for survival analysis. These factors were studied by Cox proportional hazard regression model for univariate and multivariate regression analysis. Results: In this study, there were 38 cases of probable MSA patients (44.7 %), 47 cases (55.3 %) of possible MSA patients, 43 cases (50.6 %) with Parkinson's disease-like symptoms (MSA-P), 42 cases (49.4 %) with cerebellar syndrome (MSA-C). Among them, 46 patients (54.1 %) were male, 39 patients (45.9 %) were female, with onset age of 54.7 ± 8.8 years. 30 patients (35.3 %) suffered from the onset of motor symptoms, 55 patients (64.7 %) suffered from the onset of non-motor symptoms. The median time between onset of MSA and non-motor symptoms combined with motor symptoms was 27.9 (11.5, 40.5) months. As of the end of the study, 28 patients (32.9 %) were able to walk independently, and 57 patients (67.1 %) were unable to walk independently. The median time between onset of MSA and dependent ambulation was 36.0 (22.5, 54.0) months. The Cox proportional hazard regression model suggested an old age (HR=1.041, 95 % CI 1.000 to 1.083, P=0.049), H&Y high-stage (HR=2.015, 95 % CI 1.031 to 3.938, P=0.040), short duration from onset of MSA to non-motor symptoms combined with motor symptoms (HR=0.980, 95 % CI 0.967 to 0.993, P=0.003) were independent risky factors for predicting the development of MSA patients to dependent ambulation. Conclusion: The old age, H&Y high- stage, short duration from onset of MSA to non-motor symptoms combined with motor symptoms are prognostic risk factors for MSA patients. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的探讨磁共振成像小脑中脚宽度对多系统萎缩( MSA ) 症的诊断及与帕金森病( PD ) 鉴别诊断中的 效能。方法采用磁共振成像( MRI) 检查测量132 例MSA 患者（ 包括MSA-C 型及MSA-P 型） 和54 例PD 患者及 30 例正常对照者的小脑中脚宽度，并采用ROC 评估磁共振成像小脑中脚宽度对MSA 的诊断及与PD 的鉴别诊断 效能。结果MSA 患者双侧小脑中脚宽度[ ( 6. 73 土1 . 80 ) mm ] 小于正常对照者[ ( 10. 37 口17 ) mm) 及PD 患者 [ ( 9. 95 土1 . 88 ) mm] ( P 均< 0. 05 ) 。MSA-P 型患者小脑中脚宽度[ ( 7. 85 土1 . 86 ) mm ] 大于MSA-C 型[ ( 6 . 20 土 1 . 52 ) mm] ( P < 0. 05 ) 。磁共振成像小脑中脚宽度诊断MSA 的ROC 下AUC 为0. 945 ( P < 0. 05 ) ， 最住诊断界值为 8. 325 mm ， 敏感度94. 4% ， 特异度84. 8% 。磁共振成像小脑中脚宽度诊断MSA-C 型的ROC 下AUC 为0. 784 ， 最住 诊断界值7. 325 mm ， 敏感度69. 0% ， 特异度80. 0% 。结论磁共振成像小脑中脚宽度对MSA 有较好的诊断效能， 且有助于MSA 的分型及与PD 的鉴别诊断。 [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Contemporary Neurology & Neurosurgery is the property of Chinese Journal of Contemporary Neurology & Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

多系统萎缩(MSA)是目前在医学上比较罕见的病例之一,为中枢神经系统的变性疾病,MSA通常病因不明,好发于50~60岁人群,无家族史,病情发展缓慢,进行性加重,无特殊治疗手段.本院2015年8月收治1例MSA患者,经过精心诊治和护理,患者治疗效果显著,病情好转出院. [ABSTRACT FROM AUTHOR]