Search

Copyright of Journal of Physical Education / Tiyu Xuekan is the property of Journal of Physical Education Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the relationship between blood coagulation, fibrinolysis and fibrosis with chronic hepatitis B virus infection state. Methods: 120 patients with chronic hepatitis B virus infection in our hospital were selected. After test, the patients were divided into immune clearance group, immune tolerance group, inactive group and control group, 40 cases in each group. The blood coagulation, fibrinolysis and fibrosis level was detected and the correlation of these indexes with infection state of the patients was analyzed. Results: Compared with control group, the fibrinolytic and coagulation function in the remaining groups were decreased, and the fibrosis level was increased significantly; compared with the inactive group and immune tolerance group, the changes of indexes of immune clearance group were more obvious; between the inactive group and the immune tolerance group, there was no significant difference (P>0.05). The coagulation function negatively correlated with HBV infection, while the fibrinolysis and fibrosis was positively correlated with HBV infection. Conclusions: The infectious status of chronic hepatitis B virus is different, then the content of coagulation and fibrinolysis and fibrosis level are significantly differential, which can be used to monitor the development of this disease and be worthy of clinical promotion. [ABSTRACT FROM AUTHOR]