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BACKGROUND: Prosthesis misalignment and patient bone condition are important factors affecting the prognosis of unicompartmental knee arthroplasty, and postoperative osteoarthritic progression of the lateral compartment is a major complication leading to its high revision rate. Therefore, this will become a hot research topic in the future. OBJECTIVE: To analyze the effect of different femoral prosthesis tilt angles on the stress on the structure of the lateral compartment after unicompartmental knee arthroplasty in patients with normal bone and osteoporosis, and to investigate the correlation between osteoporosis and osteoarthritis of the lateral compartment in the postoperative period. METHODS: Using a validated finite element model of the knee, normal bone (M1) and osteoporotic (M2) unicompartmental knee arthroplasty were modeled. The femoral prosthesis tilt models (normal bone group: varus angles of 3°, 6°, 9°, 12°, and 0°, valgus angles of 3°, 6°, 9°, 12°; osteoporosis group: varus angles of 3°, 6°, 9°, 12°, 0°, valgus angles of 3°, 6°, 9°, 12°) were established respectively, totaling 18 working conditions. The effects of different femoral prosthesis tilt angles on stress magnitude and distribution in the meniscus, tibial cartilage, and femoral cartilage of interstitial compartment were evaluated. RESULTS AND CONCLUSION: (1) The high stress values on the meniscus surface and tibial cartilage surface of the healthy lateral compartment of the two models increased with the increase of the prosthesis varus angle, and decreased with the increase of the prosthesis valgus angle. Under the same working conditions, the peak stress on the meniscus surface of the osteoporotic group was greater than that of the normal bone group, but that of the tibial cartilage surface of the osteoporotic group was less than that of the normal bone group. (2) The high stress values on the femoral cartilage of the lateral compartment of the two models increased with the increase of the prosthesis varus and valgus angles. Under the same working conditions, the peak stress on the femoral cartilage of the osteoporotic group was greater than that of the normal bone group. (3) It is indicated that when the fixed-bearing femoral prosthesis is varus, the stresses on the lateral compartment structures after medial unicompartmental knee arthroplasty in normal bone and osteoporotic knees will increase, and the increase in the stresses on the lateral intercondylar structures in osteoporotic knees will be more pronounced. Therefore, special attention should be paid to the placement of the prosthesis during unicompartmental knee arthroplasty to avoid varus and valgus of the prosthesis as much as possible. At the same time, the findings confirm that osteoporosis may exacerbate the progression of lateral compartment osteoarthritis after medial unicompartmental knee arthroplasty. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 观察保留残端重建兔前交叉韧带(ACL)术对其胫骨骨道扩大的预防作用。方法将45只新西兰兔随机分为鞘内残端保残组、牵张保残组、不保残重建组各15只,分别采用鞘内保留残端、牵张保留残端、不保留残端重建ACL。分别于术后3、6周用CT三维重建观察胫骨骨道扩大情况。结果不保残重建组骨道扩大发生率、骨道扩大程度高于鞘内残端保残组、牵张保残组(P均<0.05),鞘内残端保残组、牵张保残组以上指标比较差异无统计学意义(P均>0.05)。不保残重建组骨道扩大类型以空洞型为主,鞘内残端保残组、牵张保残组以线型多见。结论与不保留残端重建兔ACL相比,保留残端重建ACL能够降低术后骨道扩大的发生率和扩大程度。 [ABSTRACT FROM AUTHOR]

目的 比较单次股神经联合坐骨神经阻滞与关节腔周围“鸡尾酒”注射在全膝关节置换术（TKA)后镇痛 中的应用效果。方法选择单侧膝关节骨关节炎患者70例，随机分为联合阻滞组和鸡尾酒组各35例，均行TKA。 联合阻滞组配制1%利多卡因2 mL +0.2%罗哌卡因3 mL的混合液，术后行单次股神经联合坐骨神经阻滞;鸡尾 酒组配制0.2%罗哌卡因5 mL +吗啡3 mL +复方倍他米松2 mL+生理盐水40 mL的“鸡尾酒”混合液，术中于关 节腔周围进行注射。术后4、6、12、24、36、48h行静息状态以及被动运动状态视觉模拟评分（VAS)，术后2周、1个 月、3个月、6个月行膝关节学会评分系统（KSS)评分，测量患侧膝关节最大屈曲度、最大伸直度以及不良反应发生 情况。结果鸡尾酒组术后各时点静息状态、被动运动状态VAS均高于联合阻滞组，<0.05。两组术后各时 点KSS评分和膝关节最大屈曲度、最大伸直度比较，>0.05。联合阻滞组术后心动过缓、尿潴留、恶心呕吐、瘙 痒及低血压等不良反应发生率均低于鸡尾酒组，/均<0.05。结论单次股神经联合坐骨神经阻滞用于TKA后的 镇痛效果优于术中关节腔周围“鸡尾酒”注射，且不良反应较少。 [ABSTRACT FROM AUTHOR]