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Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the relationship between serum Klotho protein, visinin-like protein 1 (VILIP-1), high mobility group box 1 protein (HMGB1) and cognitive function and prognosis in patients with Alzheimer's disease (AD). Methods: 136 patients with AD who received treatment in our hospital from April 2019 to May 2021 were selected as the AD group, and another 150 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The expression levels of serum Klotho protein, VILIP-1 and HMGB1 in the two groups were detected by enzyme-linked immunosorbent assay. The cognitive function in the two groups was assessed by the Mini-Mental State Examination Scale (MMSE), and the relationship between the above three indicators and MMSE score was analyzed by Pearson correlation. The patients with AD were divided into good prognosis group (n=74) and poor prognosis group (n=62) according to the prognosis at 1 year after treatment. Univariate and multivariate Logistic regression were used to analyze the risk factors of poor prognosis in patients with AD. Receiver operating characteristic (ROC) curve was used to evaluate the predictive efficacy of combined detection of serum Klotho protein, VILIP-1 and HMGB1 in patients with AD. Results: MMSE score and serum Klotho protein level in the AD group were significantly lower than those in the control group, while serum VILIP-1 and HMGB1 levels were significantly higher than those in the control group (all P<0.05). Pearson correlation results showed that serum Klotho protein level was significantly positively correlated with MMSE score (P<0.05), while serum VILIP-1 and HMGB1 levels were significantly negatively correlated with MMSE score (all p<0.05). Multivariate Logistic regression analysis showed that increased serum VILIP-1 and HMGB1 levels were independent risk factors for poor prognosis in patients with AD, while increased serum Klotho protein level was a protective factor (P<0.05). ROC curve showed that the area under the curve of Klotho protein, VILIP-1 and HMGB1 in the combined detection of patients with AD was 0.839, the sensitivity was 80.65%, and the specificity was 83.78%. Conclusion: The serum Klotho protein, VILIP-1 and HMGB1 expression levels are strongly correlated with the cognitive function and prognosis of patients with AD, and the above three indicators can be used to assist the prognosis assessment of patients with AD. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Application Research of Computers / Jisuanji Yingyong Yanjiu is the property of Application Research of Computers Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Dalian Polytechnic University is the property of Journal of Dalian Polytechnic University Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Dalian Polytechnic University is the property of Journal of Dalian Polytechnic University Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Natural Gas Industry is the property of Natural Gas Industry Journal Agency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Xinyang Normal University Natural Science Edition is the property of Journal of Xinyang Normal University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Control Theory & Applications / Kongzhi Lilun Yu Yinyong is the property of Editorial Department of Control Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Automatica Sinica is the property of Chinese Academy of Sciences, Institute of Automation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

ANG is a kind of new technology to adsorb natural gas. In charge and discharge process, it shows heat effects. The heat of adsorption is about 16 kJ/mol, and it influences adsorption capability about 20%. Based on the temperature field distribution of storage vessel and the comparison of structures with or without heat exchange, the heat effects of during absorption process was mainly discussed, the variation of temperature at different radial positions and influences of heat effects on temperature fields were analyzed, and experimental data were compared with. The results showed that using heat exchange structure had good effect to retard the heat effect of adsorption process. [ABSTRACT FROM AUTHOR]