Search

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The pain of patients after total knee arthroplasty seriously affects the efficacy of surgery and patient satisfaction, which is a clinical problem concerned by joint surgery experts all over the world. OBJECTIVE: To observe the efficacy of Tuina in the treatment of pain after total knee arthroplasty in patients with knee osteoarthritis. METHODS: In a randomized controlled design, 134 patients with unilateral knee osteoarthritis scheduled for total knee arthroplasty were randomly divided into two groups: Tuina group (n=67) and control group (n=67). The control group was treated with routine postoperative analgesia, and the Tuina group was treated with Tuina on the basis of the control group. The intervention time was set from the first day to the seventh day after operation. The pressure pain threshold, visual analogue scale score, times of patient-controlled analgesia, additional dose of analgesics, range of motion of knee joint, Hamilton anxiety scale score, and adverse events were recorded in the two groups. The study was approved by the Ethics Committee of Shanghai Guanghua Integrated Chinese and Western Medicine Hospital on October 12, 2019, approval No. 2019-K-24. All participants gave informed consent to the trial protocol and process, and signed informed consent. This study was registered at the Chinese Clinical Trial Registry (http://www.chictr.org.cn/searchproj.aspx, ChiCTR1900027810) on November 29, 2019. RESULTS AND CONCLUSION: (1) After 3 and 7 days of intervention, the pressure pain threshold in the Tuina group was higher than that in the control group (P < 0.05). (2) After 3 and 7 days of intervention, the visual analogue scale score in the Tuina group was lower than that in the control group (P < 0.05). (3) The pressing times of patient-controlled analgesia after 2 days of intervention and the additional dose of analgesics after 7 days of intervention in the Tuina group were less than those in the control group (P < 0.05). (4) After 3 and 7 days of intervention, the range of motion of knee joint in the Tuina group was better than that in the control group (P < 0.05). (5) After 3 and 7 days of intervention, the Hamilton anxiety scale score in the Tuina group was lower than that in the control group (P < 0.05). (6) There were no adverse events in both groups. (7) It is indicated that Tuina can improve the local pain threshold of knee after total knee arthroplasty in patients with knee osteoarthritis, reduce the use of analgesics, and promote the rehabilitation of knee, which is safe and reliable. [ABSTRACT FROM AUTHOR]

BACKGROUND: Tuina for knee osteoarthritis has obvious curative effect, and has been widely used in clinical practice due to its characteristics, including simple operation, popularization, and good comfort. OBJECTIVE: To observe the clinical effect of the combination of pressing points of local acupoint plus adjustion of the knee joint in a sitting position in the treatment of knee osteoarthritis under “emphasizing both bones and tendons” as the guiding ideology of Tuina. METHODS: Ninety-one patients with knee osteoarthritis were randomly divided into a treatment group (n=46) and a control group (n=45). The treatment group was given the pressing points of local acupoint plus adjustion of the knee joint in a sitting position, and the control group was treated with oral celecoxib for 4 weeks. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, the pressure pain thresholds, the Visual Analogue Scale scores at rest and at movement, and Hospital Anxiety and Depression Scale score were analyzed before and after treatment. The total clinical efficacy and adverse reaction index score were observed. The study was approved by the Ethics Committee of Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine on June 5, 2017, approval number: 2017-k-11. All participants were informed of the trial protocol and process, and signed informed consent. This study was registered at the Chinese Clinical Trial Registry (http://www.chictr.org.cn/searchproj.aspx, ChiCTR1900022928) on May 4, 2019. RESULTS AND CONCLUSION: After 4 weeks of treatment: (1) The scores of WOMAC in both groups were improved compared with the baseline, and those in the treatment group decreased more significantly (P < 0.05); (2) the pressure pain thresholds of two groups were significantly improved compared with the baseline, and the treatment group was better than the control group (P < 0.05); (3) the Visual Analogue Scale scores at rest and at movement in the treatment group were decreased significantly compared with those in the control group (P < 0.05); (4) the scores of Hospital Anxiety and Depression Scale in terms of depression and anxiety in the treatment group were significantly lower than those in the control group (P < 0.05); (5) the total effective rate of the treatment group was 93.18%, and the control group was 81.40%, with significant difference between the two groups (P < 0.05); (6) there was no significant difference in the adverse reaction scores between the two groups (P > 0.05). Overall, the above results indicate that with “emphasizing both bones and tendons” as the guiding ideology of Tuina, the clinical effect of the pressing points of local acupoint and adjustion of the knee joint in a sitting position in the treatment of knee osteoarthritis is better than that of oral celecoxib. [ABSTRACT FROM AUTHOR]