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Objective To investigate the effect of transitional care model on postpartum depression of primiparas. Methods Totally 400 primiparas were randomly divided in to the control group and observation group, with 200 cases in each group. Primiparas in the control group received routine nursing and health education, and those in the observation group were given transitional care. The Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were used to measure the psychological states. The Pittsburgh Sleep Quality Index (PSQI) was used for sleep quality measurement. The incidence of postpartum depression and satisfaction degree were investigated. Results Scores of SDS and SAS were decreased in both two groups after intervention, and Scores of SDS and SAS in the observation group were lower than those in the control group (P＜0. 01). Score of PSQI was decreased in both two groups after intervention, and score of PSQI in the observation group was lower than that in the control group(P＜0. 01). Compared with those in the control group, A lower incidence of postpartum depression and higher satisfaction degree were reported in the observation, with a significant difference(P＜0. 01). Conclusion The transitional care model, as a proved way of optimizing quality of postpartum nursing, is effective to relieve the primipara’s negative emotion, improve the sleep quality and reduce the incidence of postpartum depression. (目的 探讨产后延续护理对初产妇产后抑郁的影响, 分析优化措施。方法 采用随机数字表法进行分组, 将2019年1月—2022年1月接诊的400例初产妇分为两组: 对照组200例, 提供常规指导; 观察组200例, 提供产后延续护理。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评价心理状态; 采用匹兹堡睡眠质量指数量表(PSQI)评估睡眠质量; 对比两组产后抑郁发生率、产妇满意度。结果 干预后, 两组SDS和SAS量表评分均较干预前下降, 且观察组SDS、SAS评分低于对照组, 差异有统计学意义(P＜0. 01)。干预后, 两组PSQI评分均较干预前下降, 且观察组PSQI评分低于对照组, 差异有统计学意义(P＜0. 01)。观察组产后抑郁发生率低于对照组(P＜0. 01)。观察组产妇满意度高于对照组(P＜0. 01)。结论 对初产妇实施产后延续护理, 能够改善产妇的负面情绪, 提高睡眠质量, 降低产后抑郁的发生率, 提高产妇的护理满意度, 进一步优化产后延续护理质量。)

针对电动汽车（electric vehicle，EV）大规模接入电网充电造成的过载风险问题，提出了计及预测负荷和用户需求差异的电动汽车实时优化策略。首先，根据签约与否将入网EV分为签约用户和非签约用户，通过分析实际场景将非签约用户纳入为需求响应对象，并根据用户的充电需求差异将其分为不同类别并建立相应的模型。其次，引入非签约用户响应概率与补偿电价的关系模型，建立聚合商和用户的补贴机制，根据电网需求和各类用户潜力制定各时段的实时调度方案。然后以配电网控制目标功率为约束，以聚合商盈利增比和用户平均收益增比为综合优化目标，采用粒子群算法分时段求解参与需求响应的EV充电功率。最后，经过多组仿真分析，证明了所提优化策略在削减负荷峰值的同时可以兼顾聚合商和用户的收益，验证了所提实时调度策略的有效性以及适用性。

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[Objective] The improved combination weighting method and VIKOR method were discussed, in order to enrich cigar quality evaluation methods. [Method] The chemical composition of Yunnan cigar filler was taken as research object, coefficient of variation and coefficient of multiple correlation were introduced to improve the traditional CRITIC method and e0/4~e8/4 scale was used to replace the 1-9 scale in AHP, while combined weights were calculated based on game theory. VIKOR method by non-weight individual regret was used to evaluate chemical quality of cigar filler. [Result] Compared with the weights of chemical components determined by the traditional CRITIC method, potassium weight in the improved CRITIC method was increased by 1.09 times, and reducing sugar weight was decreased by 45. 26%. Compared with e0/4~e8/4 scale AHP and 1-9 scale AHP, the weight orders were consistent, and the differences between weights of different chemical components were reduced. The improved VIKOR method and the traditional method had a high consistency in the ranking results of the chemical quality of cigar filler, but there were also significant differences, indicating that it was necessary to consider the influence of weights in the individual regret. [Conclusion] Improved CRITIC method can solve the problem that the determination of the weight in traditional method is affected by the unit of measurement and the positive or negative of indexes; The improved AHP method significantly improves the consistency of the judgment matrix through the new scale; The improved VIKOR evaluation method comprehensively considers the overall performance of chemical quality, while highlights the role of the poorly performing chemical components. The evaluation results are relatively reasonable. [ABSTRACT FROM AUTHOR]

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针对单载波传输速率不断提升对超长距无中继通信的传输跨距带来巨大挑战的问题，文章主要采用高阶泵浦前后向遥泵放大技术，结合G.654E超低损、大有效面积光纤及子载波频分多路复用技术，通过优化高阶泵浦功率、远程增益单元性能、线路放置位置和信号波传输波长等光路子系统参数，实现了单跨距501.18 km（78.68 dB）单载波400 Gbit/s无中继单纤芯超长距离传输。

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BACKGROUND: Natural bone morphogenetic protein 2 disperses and degrades rapidly in vivo, reducing local concentration and therapeutic efficacy. Simply combining bone morphogenetic protein 2 with tissue engineering scaffolds could not stay in vivo for a long time, making it difficult to achieve good sustained and controlled release effects. OBJECTIVE: To prepare and test the biological properties and chondrogenic induction effect of collagen-binding domain-bone morphogenetic protein 2-collagen cartilage scaffold. METHODS: SD rat tail collagen was extracted and a collagen cartilage scaffold was prepared using a vacuum freeze-drying machine chemical crosslinking method. The plasmid expressing collagen-binding domain-bone morphogenetic protein 2 was constructed by rapid cloning C112 homologous recombination, constructed by genetic engineering, and introduced into E. coli, and then collagen-binding domain-bone morphogenetic protein 2 was isolated and purified. Natural bone morphogenetic protein 2 and collagen-binding domain-bone morphogenetic protein 2 were combined with collagen cartilage scaffolds, respectively, to detect the release level of bone morphogenetic protein 2 in the scaffolds. The biocompatibility of collagen-binding domain-bone morphogenetic protein 2-collagen cartilage scaffold was detected by CCK-8 assay and F-Actin staining. Bone marrow mesenchymal stem cells were implanted on two kinds of collagen cartilage scaffolds for chondrogenic induction, and their chondrogenic induction activity was tested. RESULTS AND CONCLUSION: (1) The binding rate of collagen-binding domain-bone morphogenetic protein 2 to collagen cartilage scaffolds was higher than that of natural bone morphogenetic protein 2 (P < 0.05). After being immersed in PBS for 7 days in vitro, the release of bone morphogenetic protein 2 in the collagen-binding domain bone morphogenetic protein 2-collagen cartilage scaffold was smaller than that in the natural bone morphogenetic protein 2-collagen cartilage scaffold (P < 0.05). The results of the CCK-8 assay and F-Actin staining showed that the collagen-binding domain-bone morphogenetic protein 2-collagen cartilage scaffold had no obvious cytotoxicity and had good biocompatibility. (2) After 14 days of chondrogenic induction, ELISA detection demonstrated that the expressions of agglutincan and type II collagen A1 in the collagen-binding domain-bone morphogenetic protein 2-collagen cartilage scaffold group were higher than those in the natural bone morphogenetic protein 2-collagen cartilage scaffold group (P < 0.05). Under scanning electron microscopy, more bone marrow mesenchymal stem cells were observed on the inner wall of the pores of the two groups of scaffolds, and the cell morphology and size were the same, and the cells were closely arranged, without cell fragmentation or abnormal morphology. (3) The results indicate that the collagen-binding domain-bone morphogenetic protein 2-collagen cartilage scaffold has good biological properties and chondrogenic induction activity. [ABSTRACT FROM AUTHOR]

This study investigated the effect of substituting chemical fertilizer with vermicompost and bio-organic fertilizer under equal amounts of N, P2O5, and K2O levels on peanut yield, nitrogen absorption, and fixation under continuous cropping. A two-year experiment was conducted in the long-term continuous cropping field of peanuts, including four treatments, such as vermicompost substituting chemical fertilizer(VM), bio-organic fertilizer substituting chemical fertilizer(BF), NPK chemical fertilizer(CF), and no fertilizer treatment as control(CK). The effect of organic fertilizer substituting chemical fertilizer on peanut yield and nitrogen uptake and utilization were studied. The results showed that VM treatment significantly increased peanut plants′ harvest index and dry matter accumulation. The peanut yield of VM and BF treatments increased by 63.18% and 33.51% compared with CK. CF significantly reduced nodules′ number and fresh mass by 18.78%-50.82% and 24.29%-34.74%, respectively. Compared with CF, BF and VM increased the number of nodules by 53.20% and 69.56%, and fresh mass of nodules by 63.90% and 66.31%, respectively. The nitrogenase activity of BF and VM was 1.16 and 1.20 times that of CK and 1.15 and 1.19 times that of CF, respectively. The nitrogen content and nitrogen accumulation of peanut grain, leaf, stem, and root under fertilization treatment were higher than CK, among which VM treatment was the highest, followed by BF treatment. The nitrogen allocation ratio of peanuts was higher in grain than in leaf, stem, and root. VM increased the nitrogenase fixation potential of peanut nodules and the nitrogen allocation ratio to the grain but decreased the nitrogen allocation ratio to the root, while CF showed the opposite effect. The agronmic efficiency of nitrogen fertilizer of VM was 1.85 and 5.08 times that of BF and CF, respectively. partial factor productivity from applied nitrogen of VM(5.02 kg·kg-1 )and BF(4.11 kg·kg-1 )was significantly higher than that of CF(3.43 kg·kg-1 )and CK(3.08 kg·kg-1 ). Compared with CF and BF, VM showed stronger nitrogen uptake and utilization capacity. In summary, vermicompost substituting chemical fertilizer treatments enhanced the ability to convert peanut photosynthetic products into economic products, showing a stronger yield advantage. NPK chemical fertilizer showed a pronounced “Nmin inhibitory effect” while organic fertilizer (especially vermicompost) substituting chemical fertilizer treatments could alleviate the “Nmin inhibitory effect” which was mainly attributed to the fact that vermicompost substituting chemical fertilizer treatments could maintain the nitrogen fixation potential of nodules by increasing the nitrogenase activity of nodule, and changed the nitrogen allocation of peanut plants, and finally enhanced the nitrogen uptake and utilization capacity of peanut plants. [ABSTRACT FROM AUTHOR]

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Objective: The nanovesicle derived from hum, an umbilical cord mesenchymal stem cells (HUC-MSCs) can be used for drug targeting through a variety of methods. The aim of this study is to construct the CD64 (FcγRI) coated nanovesicle from the HUC-MSCs, and to detect the efficiency of antibodies (IgG1/IgG3) loading and cell entry of the nanovesicle. Methods: HUC-MSCs were isolated by tissue-cutting and cell culture method; A pLV-CD64 lentivirus packaging vector was established and packaged in the lentivirus; The lentivirus was transfected into HUC-MSCs, and the cell line that stably express CD64 was selected; The CD64 expressing HUC-MSCs was denuclearizated using the cytochalasin B co-incubation/centrifugation method; The nanovesicle with a diameter of approximately 200 nm was generated by ultrasound and gradient extrusion methods. The nanovesicle was co-incubated with anti-EGFR IgG1 antibodies for antibody loading, and the entry efficiency of the nanovesicle was investigated in A549 cells. Results: The nanovesicle with the diameter of 195± 82 nm, was obtained using the cytoplast of HUC-MSCs. The nanovesicle was stably expressing CD64 and successfully loaded with EGFR antibody; The modification effectively improved the entry efficiency of the nanovesicle for target cells. Conclusions: A nanovesicle with the capable of loading IgG1 antibodies was constructed, which could efficiently improve its entry efficiency for target cells. [ABSTRACT FROM AUTHOR]

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随着能源利用终端多能耦合程度的加深，配电网网络重构需充分考虑多能耦合之间的影响，以配电网快速灵活的重构操作提升综合能源系统的优化水平。基于此，建立了考虑配电网网络重构的电-气综合能源系统（integrated electric power and natural gas system,IEGS）优化运行模型。一方面，在最小化IEGS运行成本的基础上，利用条件风险价值理论（conditional value at risk,CVaR）量化IEGS源-荷不确定性所带来的运行风险，将其折算为成本统一到目标函数中；另一方面，考虑多能耦合约束，将配电网络重构映射到IEGS运行优化模型中，潮流模型中引入重构开关控制变量，构建支路开断潮流约束和配电网辐射状约束，并对其进行线性化处理。算例结果表明，在IEGS中考虑配电网网络重构可提升IEGS运行能力，而利用CVaR计及了源荷不确定性，使得IEGS中配电网重构结果更具鲁棒性。

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From the pre-Qin to the Han and Jin Dynasties, the primitive agriculture of the Beipan River basin in the western part of the Guizhou Plateau underwent major changes, and the process of agricultural change can be divided into three stages according to the changes in production tools, technology, and variety of food crops. The main reason for the change was that the two migrations of Dian and Han immigrants from the Warring States period to the East Jin, West Jin and Southern Dynasties brought advanced agricultural tools and technology, and the primitive agriculture in the Beipan River basin entered the stage of farming with hoes and ploughs, and the production mode of traditional agriculture appeared. However, advanced agricultural methods did not spread in the Beipan River basin, and the local area maintained a situation where multiple means of livelihood and agricultural production patterns coexisted. [ABSTRACT FROM AUTHOR]

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