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Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To study the efficacy and safety of bronchoalveolar lavage in the treatment of patients with severe CAP．Methods 76 patients with severe CAP were selected fromAugust，2016 to November，2018 in Ganmei Hospital Affiliated to Kunming Medical University(The First People's Hospital of Kunming) .All patients were randomly divided into 2 groups:treatment group (n = 38) and control group (n = 38) .The treatment group was treated with bronchoscopy and alveolar lavage. After 7 days， body temperature fluctuation， white blood cell， blood gas analysis (PaO2 and PaCO2) and total hospitalization time were observed.At the same time，we observedwhether there were serious adverse events during hospitalization in the two groups．Results After treatment， body temperature[treatment group(37.082±0.7822)℃，control group (37.603±0.7779) ℃]， white blood cell[treatment group (9.058±1.8232) ×109，control group (11.41±.0599) ×109] and PaCO2[treatment group (42.84±6.092) mmHg，control group (48.63±6.162) mmHg] were decreased in the two groups，and the difference was statistically significant(P<0.05) .At the same time， the effect of bronchofiberscope lavage in the treatment group was more significant， and the decrease was more obvious， the difference was statistically significant (P<0.05) .After treatment， PaO2 [treatment group(82.12±8.867) mmHg，control group (67.87± 9.154) mmHg ]increased， and the difference was statistically significant compared with that before treatment( < 0.05) .At the same time， the curative effect of bronchoscopy lavage in the treatment group was better and the increase was more significant than the control group，the difference was statistically significant(P<0.05) .Hospitalization time [treatment group (13.97±3.537) d，control group (20.19±3.763) d]of patients in the treatment group was shorter than that in the control gorup， the difference was statistically significant(P<0.05) ．Conclusion Bronchoscope alveolar lavage has significant clinical effect and no serious adverse reactions in the treatment of patients with severe CAP. [ABSTRACT FROM AUTHOR]