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Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Zone Research / Ganhanqu Yanjiu is the property of Arid Zone Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Stable intertrochanteric fractures can be treated by closed reduction and internal fixation, but there is no absolute advantage for unstable intertrochanteric fractures with osteoporosis. OBJECTIVE: To investigate the efficacy of arthroplasty in the treatment of unstable intertrochanteric fractures in the elderly with osteoporosis by comparing the indexes related to closed reduction internal fixation and arthroplasty. METHODS: Clinical data of 102 elderly patients with unstable intertrochanteric fractures of the femur treated in Affiliated Hospital of Qingdao University from January 2017 to January 2020 were retrospectively analyzed. Patients were divided into two groups according to the surgical method. In the Gamma3 group, 62 cases received Gamma3 internal fixation system. In the joint replacement group, 40 cases received an artificial femoral head replacement or total hip replacement. Surgical information, hospitalization, hip function, and postoperative complications were compared between the two groups. RESULTS AND CONCLUSION: (1) There were statistical differences between the Gamma3 group and the joint replacement group in weight-bearing time (P < 0.001), hospital stay (P < 0.05), intraoperative bleeding (P < 0.001), and length of surgery (P < 0.001). The mean weight-bearing time and hospital stay were shorter in the joint replacement group than in the Gamma3 group. Intraoperative bleeding and duration of surgery were better in the Gamma3 group than in the joint replacement group. (2) There was no significant difference in Harris hip score, subitem centesimal hip score, and postoperative complications 12 months after surgery in both groups (P=0.526, 0.788, 0.228). (3) It is indicated that arthroplasty has achieved better outcomes in the treatment of elderly unstable intertrochanteric fractures combined with osteoporosis, enabling early weight bearing and functional exercise. Careful selection of the appropriate patient and prosthesis type for arthroplasty will result in greater patient benefit. [ABSTRACT FROM AUTHOR]

Copyright of Psychological Science is the property of Psychological Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Architectural Journal / Jian Zhu Xue Bao is the property of Architectural Journal Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Body dissatisfaction is prevalent among young women and adolescents, bringing many negative effects and hindering the healthy development of adolescents. Therefore, it is crucial to understand the related factors of body dissatisfaction. This review summarizes recent literature on body dissatisfaction from the aspect of sociocultural, individual psychological, and biological factors, so as to provide theoretical foundation for the construction of relevant factor model of body dissatisfaction and also the development of body intervention projects in the future. [ABSTRACT FROM AUTHOR]

Copyright of Psychological Science is the property of Psychological Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

With the aging process of society accelerating, the prevalence of Parkinson’s disease (PD) is rising. In recent years, plenty of evidence has proved that neuroinflammation plays a vital role in the progression of PD, especially around the risk areas in the basal ganglia and substantia nigra (SN) . The damage and hyperactivation of microglia trigger oxidative stress, mitochondrial autophagy and autophagy dysfunction, the accumulation of α ⁃ synuclein and the release of pro ⁃ inflammatory cytokines, the neuronal damage mediated by these injury factors can further aggravate the activation of microglia, emphasizing the importance of this vicious cycle in the pathogenesis of PD. Therefore, exploring the role and mechanism of microglia in the pathogenesis of PD is of great significance for the diagnosis and treatment of PD. [ABSTRACT FROM AUTHOR]

智能光网络技术和P2MP（点对多点）技术的融合将能够极大地促进光组播业务的发展。文章针对多层多域光网络中的P2MP业务,提出了一种MDMPH（基于分层PCE（路径计算元素）的多域最小代价路径启发式）算法,并进行了仿真分析。与传统的PDB（基于逐域路径）算法、E-BRPC（基于扩展的反向回溯）算法以及CTB（基于核心树）算法相比,MDMPH算法能够计算出代价更小的P2MP路径树。

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Guangdong University of Technology is the property of Journal of Guangdong University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Currently, the combined use of CRISPR/Cas9 and CRE-LOXP to prepare bromodomain-containing protein 4 (BRD4) gene knockout mice is very rare. OBJECTIVE: To construct a BRD4 gene knockout mouse model by using CRISPR/Cas9 technology combined with Cre-loxP technology that can be used to knock out the BRD4 gene fragment in the mouse genome. METHODS: According to the exon sequence of BRD4 gene, a gRNA was designed and synthesized. After gRNA was transcribed in vitro, Cas9 mRNA and plasmid containing loxp site were injected into fertilized oocytes. Cas9 cut the target fragment by recognizing the leading strand of the gRNA, and then loxp was inserted into the cleavage site. After breeding with Cre, the Cre enzyme cut the loxp site to achieve the final specific deletion effect. The fertilized oocytes were transplanted into C57BL/6N recipient female mice to obtain progeny mice. The offspring mice were sequenced to identify their genotypes. The BRD4- loxP +/- (F0 generation) mice with loxp loci being successfully introduced was bred with wild-type C57BL/6N mice, and the stably inherited mice BRD4-loxP +/- (F1 generation) were selected. Some of the BRD4-loxP +/- mice interbred with each other and some interbred with CAGGcre-ERTM mice. BRD4-loxP +/+ mice were co-expressed with BRD4-loxP+/- and CAGGcre-ERTM mice (F2 generation). The F2 generation mice were bred to obtain homozygous BRD4-loxP +/+ and CAGGcreERTM mice. BRD4 gene knockout was induced by intraperitoneal injection of tamoxifen (75 mg/kg, dissolved in corn oil) in 6-8 weeks homozygous mice for 7 consecutive days. DNA was extracted from the tail fragment of the knockout mice using adsorption column method. The expression of BRD4 gene fragment in mouse tail tissue was detected by agarose gel electrophoresis. RESULTS AND CONCLUSION: Screening using PCR revealed that mice 7, 8, 9, 10, 12, 14, 16, 19, 20, 21, 25, 42, 43, and 47 of F1 generation were identified as heterozygous mice that were successfully inserted with two alleles of loxP fragment. The F3 homozygotes bred from F2 generation were induced with tamoxifen, and PCR gel electrophoresis verified that the BRD4 gene fragment was successfully knocked out in the homozygous mice. We therefore successfully constructed BRD4 gene knockout mice using CRISPR/Cas9 technology combined with CRE-LOXP technology in this study. [ABSTRACT FROM AUTHOR]

Copyright of Advanced Engineering Science / Gongcheng Kexue Yu Jishu is the property of Advanced Engineering Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Space-Integrated-Ground Information Networks is the property of Beijing Xintong Media Co., Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industrial Minerals & Processing / Huagong Kuangwu yu Jiagong is the property of Industrial Minerals & Processing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Petrochemical Universities / Shiyou Huagong Gaodeng Xuexiao Xuebao is the property of Journal Editorial Department Of Liaoning Shihua University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Anion recognition is closely related to human life activities and of great significance to human life and its social progress. Therefore, the recognition of anions in high-performance has been the focus of research in recently years. Poly(phenylacetylene) derivatives possessing helical conformation in main chains have good optical activity and unique properties, and have potential applications in anion recognition and luminescence materials. In this work, a novel substituted poly(phenylacetylene) derivative containing amino acid and group with the function of anion recognition was synthesized, and optical activities and anion recognition abilities of the polymer were also investigated. L-alanine residue and amide group having anion recognition ability were introduced to phenylacetylene monomer, and phenylacetylene monomer (PAA-L-Ala) with optical activity was successfully synthesized via amidation reaction, deprotection of Boc group and amidation reaction. The phenylacetylene monomer was successfully polymerized in DMF (N,N-dimethylformamide) using a rhodium catalyst to yield a optically active poly(phenylacetylene) derivative (PPAA-L-Ala). The optical activities of polymer and monomer were investigated by the specific rotation and circular dichroism. The results show that the back bone of the polymer possesses a dynamic helical conformation induced by the asymmetric chiral residue. The anion recognition ability of the novel poly(phenylacetylene) derivative was evaluated using a series of tetra-n-butylammonium salts in DMF. The results indicate that PPAA-L-Ala has anion recognition ability, which can be used as a probe for selective recognition of AcO-H2PO4-OH- and F- based on circular dichroism or fluorescence spectrometer, and a probe for selective recognition of OH-and F- based on naked eyes and UV-Vis. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Remote Sensing is the property of Editorial Office of Journal of Remote Sensing & Science Publishing Co. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)