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Copyright of Journal of Practical Medicine / Shiyong Yixue Zazhi is the property of Journal of Practical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Nanchang University (Engineering & Technology) is the property of Nanchang University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the relationship between serum antithrombin Ⅲ (ATIII) and plasma monoamine oxidase (MAO) and acute coronary syndrome and their predictive efficacy for major adverse cardiovascular events in the near future after interventional procedures. Methods: Eighty-five patients with acute coronary syndrome admitted to our hospital from January 2020 to January 2023 were selected as study subjects, and the patients were grouped according to their cardiology non-ST-segment elevation acute coronary syndrome ischemia assessment (GRACE) scores, and 20 patients with GRACE scores ＞140 were divided into the high-risk group, 30 patients with scores 109-140 were divided into the medium In addition, 40 healthy patients who came to our hospital for physical examination at the same period were selected as the control group, and serum ATIII and plasma MAO expression levels of the four groups were compared, and the correlation between serum ATIII and plasma MAO and the severity of acute coronary syndrome was analyzed. Subsequently, 85 cases with or without recent adverse cardiovascular events (MACE) after PCI for acute coronary syndrome were divided into non-MACE group (n=64) and MACE group (n=21), and the clinical characteristics, serum ATIII and plasma MAO expression levels of the two groups were compared, and the correlation between serum ATIII and plasma MAO on recent major adverse predictive efficacy of cardiovascular events after acute coronary syndrome intervention. Results: There were differences in the levels of AT Ⅲ and MAO among the four groups. The level of AT Ⅲ in the high-risk group was significantly lower than that in the medium-risk group, the low-risk group and the control group, and the level of MAO in the high-risk group was higher than that in the medium-risk group, the low-risk group and the control group (P＜0.05); Spearman correlation analysis showed that AT Ⅲ and MAO were positively correlated with the severity of acute coronary syndrome, while MAO was negatively correlated with the severity of acute coronary syndrome (P＜0.05); There was no difference between the non-MACE group and the MACE group in terms of age, cardiac function grading, left ventricular ejection fraction, TIMI score, AT Ⅲ and MAO expression level (P＜0.05); The results of logistic regression analysis showed that ATIII and MAO were independent risk factors for major adverse cardiovascular events in the near future after interventional procedures for acute coronary syndromes (P＜0.05). Conclusion: Serum ATIII and plasma MAO levels were significantly correlated with the severity of acute coronary syndrome, and ATIII and MAO were independent risk factors for recent major adverse cardiovascular events after interventional procedures for acute coronary syndrome. It is suggested that clinically, for patients with acute coronary syndrome with reduced ATIII and elevated MAO, timely measures should be taken to prevent the occurrence of recent adverse cardiovascular events. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To analyze the relationship between serum sphingosine 1-phosphate, neuropeptide Y and critical coronary artery lesions and their predictive value for functional myocardial ischemia. A total of 148 patients with critical coronary artery disease admitted to our hospital from January 2020 to June 2022 were selected as the observation group. According to the vulnerability of coronary atherosclerotic plaque, they were divided into vulnerable plaque group (68 cases) and stable plaque group (80 cases). A total of 148 subjects without critical coronary artery disease were selected as matched group. The serum levels of sphingosine 1-phosphate and neuropeptide Y were detected in all subjects. The serum levels of sphingosine 1-phosphate and neuropeptide Y were compared between observation group and matched group, vulnerable plaque group and stable plaque group. Pearson correlation was used to analyze the relationship between serum sphingosine 1-phosphate and neuropeptide Y and Gensini score. The area under the receiver operating characteristic curve (AUC) was used to evaluate the predictive efficacy of serum sphingosine 1-phosphate combined with neuropeptide Y for functional myocardial ischemia. Serum levels of sphingosine 1-phosphate and neuropeptide Y in the observation group were higher than those in the matched group (P<0.05); serum sphingosine 1-phosphate and neuropeptide Y levels in the vulnerable plaque group were higher than those in the stable plaque group (P<0.05). Pearson correlation analysis showed that serum sphingosine 1-phosphate and neuropeptide Y levels in patients with borderline coronary lesions were positively correlated with Gensini score(P<0.05); among 148 patients with borderline coronary lesions, the There were 45 cases with functional myocardial ischemia; the levels of sphingosine 1-phosphate and neuropeptide Y in the functional myocardial ischemia group were higher than those in the non-functional myocardial ischemia group (P<0.05). The AUC of sphingosine phosphate combined with neuropeptide Y in predicting functional myocardial ischemia in patients with borderline coronary artery disease was 0.928. The serum levels of sphingosine 1-phosphate and neuropeptide Y are increased in patients with critical coronary artery disease, which are closely related to the severity of the disease, the combined prediction of functional myocardial ischemia has a high accuracy, which is worthy of clinical attention. [ABSTRACT FROM AUTHOR]

Copyright of Journal of South China University of Technology (Natural Science Edition) is the property of South China University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Guangdong Agricultural Sciences is the property of South China Agricultural University, Guangdong Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To compare the accuracy of glomerular filtration rate (GFR) test with Deming cycle management model (PDCA) and conventional management model. influences. Methods A retrospective analysis was performed on 1102 patients with abnormal renal function who underwent GFR examination in our hospital from January 2018 to December 2019. The 311 patients who underwent GFR examination under the routine management mode were used as the control group, and the 801 patients who underwent GFR examination under PDCA were used as the observation group. Fishbone diagram, Plato, and root cause analysis were used to explore the main reasons, and the GFR levels and accuracy of the two groups of patients were compared. Test, χ2 test and t test were used to conduct statistical analysis on inaccurate items caused by irregular operation. Result The same worker for repeated processing of the image obtained The left kidney GFR levels were (41.200±8.130) and (40.920±7.410) mL/min, respectively, and the right kidney GFR levels were (34.370±7.410) mL/min. 12.140), (33.560±12.090) mL/min, the difference was not statistically significant (P>0.05); The GFR levels were (37.930±10.240) and (38.300±9.850) mL/min, respectively, and the GFR levels of the right kidney were (33.010±12.280), (32.870±12.170) mL/min, the difference was not statistically significant (P>0.05); Manual and automatic delineation of bilateral kidney imaging area, the obtained The GFR levels of the left kidney were (44.270±6.250) and (40.730±6.080) mL/min, respectively, and the GFR levels of the right kidney were (34.790±12.280, (31.950±11.330) mL/min, the difference was statistically significant (P<0.05); using manual and automatic delineation of the background area at the same position, the results were obtained. The left kidney GFR levels were (35.070±11.870) and (31.730±10.890) mL/min, respectively, and the right kidney GFR levels were (43.650±10.890) mL/min. 8.550), (39.040±8.050) mL/min, the differences were statistically significant (P<0.05); the accuracy rate of GFR level in the control group was 84.89%. Group was 98.50%, the difference was statistically significant (P=0.027). Conclusion PDCA has a significant effect in GFR examination, and can improve the examination Quality and accuracy of operations. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Dalian Polytechnic University is the property of Journal of Dalian Polytechnic University Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Studies have shown that nitric oxide (NO) can effectively improve blood supply and promote flap survival, but the specific mechanism is still unclear. OBJECTIVE: To explore the effects of L-arginine (L-Arg) on the survival of extended dorsal perforator skin flap in rats by activating L-Arg-NO pathway. METHODS: Animal models of extended dorsal perforator skin flap were successfully established in 81 male Sprague Dawley rats, which were then divided into a L-Arg group, a blank group and a L-NAME group. L-Arg (400 mg/kg per day) and nitro-amino-methyl-L-arginine (L-NAME; 40 mg/kg per day) were injected intraperitoneally in the L-Arg group and L-NAME group immediately and 1-7 days after operation, respectively, while the same volume of isotonic sodium chloride solution was injected intraperitoneally in the blank group at the same time points. Flap survival rate was measured. Angiography was performed to observe appearance and distribution of blood vessels at 7 days after operation. NO concentration of choke II zone was detected immediately, 1, 3, 5, and 7 days after operation. Tissue samples were harvested from the choke II zone for detecting density and caliber of new blood vessels using hematoxylin-eosin staining and the expression of vascular endothelial growth factor and matrix metalloproteinase was detected by western blot, respectively. The study protocol was approved by the Animal Ethics Committee of the 94th Hospital of the PLA Joint Logistics Support Force (approval No. 2015KYLL046). RESULTS AND CONCLUSION: The highest survival rate of flap appeared in the L-Arg group, (89.47±3.17)%, which was significantly higher than that in the other groups (F=49.908, P < 0.001). At 7 days after operation, the vascular structure in the choke II zone of the L-Arg group was relatively complete with clear trajectory. The vessels that had expanded to achieve true anastomosis extended along the longitudinal axis of the flap to the end of the flap. In the blank group and L-NAME group, the vascular structure and vascular trajectory in the choke II zone were disordered. Moreover, the vascular structure at the end of flap in L-NAME group disappeared. NO concentration in L-Arg group was increased after surgery, peaked at 3 days after operation, and then decreased gradually. Microvessel density and caliber in the L-Arg group were significantly higher than those in the other groups at 7 days after operation (P < 0.001). Western blot showed that the expression of vascular endothelial growth factor and matrix metalloproteinase-2 were significantly higher in the L-Arg group than the other groups at 3 after operation (P < 0.05), while at 7 days after operation, the expression of vascular endothelial growth factor in the L-Arg group was significantly higher than that in the other groups (P < 0.05), but the expression of matrix metalloproteinase-2 showed no significant difference among the three groups. To conclude, NO could promote microvascular growth and dilatation in the choke II zone of extended dorsal three-vascular perforator flaps in rats; L-Arg could increase the NO concentration in tissue by activating the L-Arg-NO pathway, which is beneficial to the survival of skin flap. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Perforator flaps are used to repair skin and soft tissue defects. As a bridge between adjacent perforator vessels, choke vessels play an important role in the survival of extended perforator flap. OBJECTIVE: To review the research status and progress of the growth of choke vessels in perforator flaps. METHODS: A computer-based search of PubMed, CNKI and SinoMed databases was performed for the relevant literature concerning the research status and progress of the growth of choke vessels in perforator flaps published from 1984 to 2017. The keywords were “perforator flap, perforator vessels, choke vessels, choke zone” in English and Chinese, respectively. RESULTS AND CONCLUSION: Totally 51 articles were included for summary. Perforator flaps are extensively used to repair skin and soft tissue defects caused by various factors. Adjacent perforter vessels are connected by choke vessels, and the extended perforter flap survival is closely related to the dilatation and growth of choke vessels. Similarity may exist between the growth of choke vessel and angiogenesis. Hypoxia and ischemic preconditioning and inflammatory environment may promote the growth of choke vessels. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To probe into the effects of rnontelukast sodium combined with budesonide for aerosol inhalation on pulmonary function and serum Immune indices of patients with cough variant asthma. METHODS: 78 patients with cough variant asthma admitted into Jiaozuo Traditional Chinese Medicine Hospital during 2016-2017 were selected and numbered to be 1-78, patients with odd numbers were classified as observation group, even numbel's were control group, with 39 cases in each group. The control group was treated with budesonide aerosol for inhalation, while the observation group was given rnontelukast sodium combined with budesonide aerosol. After an 8-week treatment, two groups were compared before and alter treatment in terms of pulmonary function [ (forced expiratory volume in first second (FEV,) and forced vital capacity (FVC)] and serum Immune indices including serum immune globulin E (IgE), tumor necrosis factor a (TNF-a) and interleukin 4 (IL-4), the incidences of adverse drug reactions of two groups were observed. RESULTS: After treatment, the FEV, and FVC levels of both groups had been significantly increased, and those of the observation group were significantly higher than the control group, with statistically significant differences (P <0.05) ; after treatment, the IgE, IL-4 and TNF-a levels of both groups had been significantly increased, and those of the observation group were significantly higher than the control group, with statistically significant differences (P<0.05). There was no statistical significance in the difference of incidences of adverse drug reactions between two groups (P >0.05). CONCLUSIONS: The efficacy of rnontelukast sodium combined with budesonide for aerosol inhalation in treatment of cough variant asthma is remarkable, which can improve patients’ pulmonary function and relieve inflammation reactions, with high safety. [ABSTRACT FROM AUTHOR]