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Inflammation is a hallmark of tumors and plays an important role in tumorigenesis, progression, metastasis and prognosis. Neutrophils, platelets, monocytes/macrophages and lymphocytes are the important components of the solid tumor-associated microenvironment such as lung cancer, and exert pro- and anti-inflammatory effects through multiple mechanisms. Their associated neutrophil-to-lymphocyte ratio, platelet-to-lymphocyteratio and lymphocyte-to-monocyte ratio can reflect the body inflammatory status and the balance between pro- and anti-tumor effects. They are the promising indicators for lung cancer screening, monitoring disease progression, efficacy and prognosis assessment. This paper reviews the relationship among inflammation, immunity and lung cancer, and the application of novel inflammatory markers in lung cancer. [ABSTRACT FROM AUTHOR]

Airway stents are mainly used in the treatment of malignant airway stenosis, as well as benign airway stenosis, softening and fistula, which can rapidly restore and maintain airway patency. However, the existing commercial stents are often difficult to avoid casuing complications. For this problem, studies on reducing stent-related complications have been conducted in recent years, with the design of airway stents becoming the focus. In order to minimize the occurrence of common complications such as stent migration, granuloma formation and mucus plugging, a variety of new airway stents have been created. However, they are still in the initial stage, often only reducing some complications, and are not currently in routine clinical practice, requiring longer cycles to verify safety and utility. Perhaps combining 3D printing technology with biodegradable materials, radioactive substances is a viable pathway and become a significant trend in the future. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the feasibility of endoscopic bronchial ultrasonography (EBUS)guided iodine-125 (125I)radioactive seeds implantation for treating mediastinal metastatic tumor and to observe its short term curative effect. Methods Twenty patients with mediastinal metastatic tumor in the respiration department of our hospital from September 2014 to March 2015 were treated by the EBUS-guided iodine-125 radioactive seeds interstitial implantation. The short-term effects were observed and the feasibility for treating mediastinal metastatic tumor was retrospectively analyzed. Results The operation procedure of the EBUS-guided iodine-125 radioactive seeds implantation brachytherapy in 20 cases of mediastinal metastatic tumor was successful. All cases had good tolerance without death case. The complications included intraoperative bleeding at puncture site in 3 cases (15%), postoperative pneumothorax in 4 cases (20%) ,lc>w fever in 5 cases (25%), hemoptysis in 7 cases (35%), which were alle-viated after symptomatic treatment. Postoperative follow-up chest CT was carried out every 2 months in all cases. The tumor diameter and physical status of all patients were obtained during follow-up. The response evaluation criteria in solid tumors (RECIST) were used to evaluate the therapeutic effect,the overall response rates(CR+PR) at postoperative 2,4,6 months were 65.00%(13/20), 80.00% (16//20) and 85.0% (17/20)respectively. The clinical symptoms in 5 cases of superior vena cava syndrome (SVCS) were significantly improved by the above treatment and the symptom alleviation reached 100.00% after 6-month follow up. No radioactive seeds shift and restenosis of superior vena cava occurred in any case. Conclusion The EBUS-guided iodine-125 radioactive seeds implantation for treating mediastinal metastatic tumor has small trauma,few complications and obvious short term effect,can effectively alleviate the pressure symptoms of superior vena cava,which is a feasible,safe and effective measure. [ABSTRACT FROM AUTHOR]