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伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病（cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy，CADASIL）是NOTCH3基因突变所致的遗传性脑小血管病，主要病变血管为颅内小动脉，累及大脑皮质和颅内大/中动脉的报道较罕见，目前缺乏特效治疗方法。本文报道1例大脑中动脉急性闭塞成功接受血管内治疗的CADASIL病例，并结合文献进行讨论，旨在引起临床医师对CADASIL可累及大脑皮质和颅内大/中动脉的重视。 Abstract: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary cerebral small vessel disease caused by mutations in the NOTCH3 gene. The main vascular pathological changes in CADASIL are intracranial small arteries, with rare reports of involvement in the cerebral cortex and intracranial large/middle arteries. There is currently a lack of specific treatment for CADASIL. This paper reported a case of CADASIL patient who successfully received endovascular treatment for acute occlusion of middle cerebral artery, and discussed the literature with the aim of raising clinical awareness of the potential involvement of CADASIL in the cerebral cortex and intracranial large/middle arteries.

文章对动态可重构光分插复用器（ROADM）进行了介绍;对实现ROADM的多种方案进行了归纳整理和简要分析;对其中解复用/开关矩阵/复用（DSM）、DSM波段、广播与选择（B&S）3种典型的ROADM结构进行了较详细的说明。文章作者设计并实现了广播与选择型ROADM,并对实验系统的上/下路功能和信道功率均衡功能进行了验证。

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Copyright of Petroleum Geology & Oilfield Development in Daqing is the property of Editorial Department of Petroleum Geology & Oilfield Development in Daqing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Nonalcoholic fatty liver disease （NAFLD） has gradually become the main reason affecting human liver health， and many factors are involved in the development and progression of NAFLD. Mitochondria， as the“ energy factory” of cells， plays an important role in maintaining normal physiological functions. Studies have shown that hepatic mitochondrial dysfunction promotes the development and progression of NAFLD. This article briefly introduces the latest research advances in the basic characteristics and physiological function of liver mitochondria and reviews new research findings in the association of mitochondrial dysfunction with obesity， simple fatty liver disease， and nonalcoholic steatohepatitis， in order to provide new ideas for the research on targeted mitochondrial therapy for NAFLD. [ABSTRACT FROM AUTHOR]

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Mr. Zeng Zhaoxuan was a famous geographer, geomorphologist, and educator in China and one of the first winners of the "geographical science achievement award" of the Chinese Geographical Society. He developed theories such as the stage development theory of flowing water topography and stage model of coral island development, and academic terms such as "stone egg" "collapse hill" "alluvial Delta" and "Danxia landform". His achievements filled the research gaps in the fields of landscape geography, historical geomorphology, and human geography. The research fields involved many disciplines such as geography, geomorphology, geology, ocean, biology, history, human, local chronicles, and cities. This study deeply analyzes his academic works, adopts the life path method of time geography to establish the academic life path according to the time latitude, and combines the academic tree method to construct his academic landscape. During his 60 years of teaching and scientific research, Mr. Zeng made indelible contributions to China's geographical science research and geographical education. First, he actively engaged in education and compiling teaching materials. While teaching and educating people, Mr. Zeng compiled a number of teaching materials for colleges and universities with wide influence. He wrote and published Geomorphology with Mr. Yau Qinshang, which won the first prize for excellent teaching materials from the State Education Commission in 1988. The textbook is easy to teach and learn, simple, and easy to understand; its research content covers a wide range, and the selected materials and achievements are novel. It is considered "shallow, broad, and new". He also compiled many teaching materials such as Comprehensive Physical Geography Fundamentals of Geomorphology and Principles cf Geomorphology. Second, he participated in the national scientific investigation work and successively participated in mountain investigations in Taiwan, geomorphic division and coastal investigation in Guangdong, investigation of Shiwandashan, investigation of karst areas in Southwest Guangxi, and a comprehensive investigation of the Pearl River Delta. Third, he dared to express his opinions, open up and innovate, and actively wrote academic papers. In scientific research, Mr. Zeng defied public opinions and actively published papers whenever he met different opinions, and expressed his unique views. He had profound knowledge, broad interests, sharp thinking, and worked hard work. He was an innovative and productive outstanding scholar. [ABSTRACT FROM AUTHOR]

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邻二甲苯废气对环境以及人体都有极大的危害.目前国内外对应用生物滴滤法处理邻二甲苯废气的研究还不多见，笔者对生物滴滤塔处理模拟邻二甲苯废气进行的研究.以邻二甲苯作为唯一碳源对某焦化厂取得的活性污泥进行驯化培养，得到能够高效降解邻二甲苯的混合培养物.利用驯化培养得到的混合培养物，对填充聚丙烯十字拉西环填料的生物滴滤塔在室温条件下进行挂膜.生物滴滤塔挂膜稳定后，考察室温20~30 ℃，pH值为5~7, 空塔气体停留时间分别为40、60、100 s条件下的生物滴滤塔处理邻二甲苯废气的效果.结果表明，该生物滴滤塔能够有效处理低浓度邻二甲苯废气，处理邻二甲苯废气效果受温度、停留时间、进气浓度等条件的影响.

The experiment was to investigate the effect of Artemisia scoparia Waldst. et Kit. powder on growth performance, antioxidant capacity and immunity of Litopenaeus vannamei. A total of 2 100 healthy white shrimp with an body length about 2.5 cm were randomly divided into seven groups, with three replicates in each group and 100 shrimp in each replicate. The shrimp in blank control group (group A) were fed with basal diet, the shrimp in positive control group (group B) were fed with basic diet and 5 ml/L Pentanthus extract was thrown into the water, and shrimp in experimental groups were fed with basal diet supplemented with 0.5%, 1.0%, 2.0%, 4.0% and 8.0% Artemisia scoparia Waldst. et Kit. powder, respectively. The experiment lasted for 42 d. The results showed that compared with group A, SR, WGR, CF, HIS, SGR were significantly increased in all groups (P<0.05), FCR significantly decreased (P<0.05). Compared with group B, WGR and SGR in Artemisia scoparia Waldst. et Kit. powder supplemental groups were significantly increased (P<0.05). Compared with group A, the content of ammonia nitrogen in all groups except 0.5% group was significantly decreased (P<0.05), except for group B, the nitrite content and pH value of whole shrimp culture water in each group were significantly decreased (P<0.05), pH value of aquaculture water in each group was significantly decreased (P<0.05). Compared with group A, MDA content in hepatopancreas in Artemisia scoparia Waldst. et Kit. powder supplemental groups was significantly decreased (P<0.05), and activitiy of SOD, CAT and PPO were significantly increased (P<0.05). Compared with group A, the mRNA expression levels of Toll-1 and Toll-2 in hepatopancreas tissues in Artemisia scoparia Waldst. et Kit. powder group were significantly decreased (P<0.05). The experiment indicates that Artemisia scoparia Waldst. et Kit. powder can promote growth, antioxidant capacity and non-specific immunity of Litopenaeus vannamei, and the appropriate supplemental ratio is 1.0%~2.0%. [ABSTRACT FROM AUTHOR]

Objective To explore the expression and significance of INHBA in cutaneous squamous cell carcinoma. Methods Immunohistochemistry,RT-PCR and western blot methods were used to measure the expression levels of INHBA in 17 cases of normal skin (NS), 30 cases of actinic keratosis (AK) and 30 cases of cutaneous squamous cell carcinoma (cSCC). Results The immunohistochemical staining indicated that the positive staining of INHBA was brown-yellow particles in the cytoplasm/nucleus, with positive rates of 23.53%, 66.67% and 86.67%, respectively, in NS, AK and cSCC (χ²=27.10,P=0.001). The relative expression levels of INHBA mRNA in NS, AK and cSCC were 1.097±0.083, 1.328±0.041, 1.731±0.064, respectively (F=48.53, P<0.001). Moreover, expression levels of INHBA mRNA were higher in AK and cSCC groups than in NS group(P<0.05), while expression levels of INHBA mRNA in cSCC group were higher than that in AK group (P=0.002). The relative expression levels of INHBA protein in NS, AK and cSCC groups were 0.850±0.011, 0.925±0.020, 1.050±0.013, respectively (F=86.62, P<0.001 among groups). Similarly, the relative expression levels of INHBA protein in AK and cSCC groups were higher than that in NS group (both P<0.05), and expression levels of INHBA protein were higher in cSCC group than in AK group (P<0.001). Conclusion cSCC tissue exhibits higher expression levels of INHBA, which may be associated with the development of cSCC. [ABSTRACT FROM AUTHOR]

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As a novel mode of cell death, pyroptosis plays an important role in nonalcoholic fatty liver disease (NAFLD), and the research on pyroptosis may help to explore new therapeutic targets for NAFLD. This article reviews the advances in pyroptosis from the research background and mechanism of pyroptosis and the role of pyroptosis in NAFLD and elaborates on the pyroptosis execution molecules such as GSDME and caspase-11 and the function of inflammasomes including AIM2. [ABSTRACT FROM AUTHOR]

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