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Aim To investigate the effect of dipeptidyl peptidase-4 inhibitor (DPP-4i) on serum creatinine (Cr) in patients with type 2 diabetes mellitus (T2DM). Methods A systematic search was performed across databases of PubMed, Embase, Cochrane Library and Web of Science, and randomized controlled trials (RCT) of DPP-4i therapy for regulating Cr in T2DM patients was included. A fixed-effect or random-effect model was used for data fitting, heterogeneity was quantitatively evaluated according to the index of I², and sensitivity analysis and publication bias testing were performed by using the standard methods. Results After searching the database through the system, 12 RCTs were included, with a total of 2 276 participants. Due to the potential heterogeneity, a random effect model was used for data fitting. DPP-4i treatment could mildly increase Cr levels in T2DM patients (WMD: 0. 15 mg / L, 95% CI: 0. 03 ~ 0. 27, I² = 18%, P= 0. 02), and the results showed statistical differences. According to sensitivity testing, the results of Meta-analysis were relatively reliable. No publication bias was observed according to Begg’ s and Egger’ s tests. Conclusions The use of DPP-4i for hypoglycemic treatment in T2DM patients may result in mild elevation of blood Cr levels. Further multicenter studies with larger samples are needed in the future to explore the clinical significance of DPP-4i treatment induced changes in Cr levels. [ABSTRACT FROM AUTHOR]

麋鹿自1985年重引进中国以来,经过繁殖扩群、行为再塑和野生放养试验3个阶段后,种群数量从79头发展至近7 000头(2018年底),先后形成江苏大丰、湖北石首和湖南洞庭湖野生麋鹿种群。通过对中国麋鹿种群发展现状调查分析,指出目前麋鹿种群健康发展面临的挑战和威胁因素,在扩大奠基种群数量、实施栖息地正向干预、加强疫病防控、开展基因交流等方面探讨中国麋鹿种群健康发展对策。

In recent years, due to the development of nuclear power and other industries, the pollution of heavy metals and radionuclides in water cannot be ignored, and the demand for clean water has become an important issue of global concern. Molybdenum disulfide (MoS2 ) nanomaterials have attracted much attention in the fields of sterilization, hydrogen storage, water purification,etc. Membrane technology has become one of the options for the removal of heavy metals and radionuclides from water based on the advantages of simple operation and high efficiency. In this paper, the research progress of MoS2-based nanomaterials and membranes in removing heavy metals and radionuclides from water is summarized, focusing on MoS2 synthesis and modification methods, the main affect factors and mechanisms of heavy metals and radionuclides removal by MoS2, the preparation of MoS2-modified membranes, and the research progress on removing heavy metals and radionuclides from water by membrane technology, which aims at efficiently removing heavy metals and radionuclides. [ABSTRACT FROM AUTHOR]

2020年5月4日在江苏盐城大丰麋鹿国家级自然保护区(120°47’—120°53’E,32°59’—33°03’N)记录到3只彩鹮。栖息地为一处浅滩水塘,3只彩鹮于水中觅食。以往曾宣布彩鹮在国内绝迹,本次记录填补了彩鹮在本地区的分布空白,证实了彩鹮在江苏省仍有分布。这一纪录或许说明本地区栖息地得到了有效的改善。

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Medical Education Technology is the property of China Medical Education Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South China Agricultural University is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To analyze the efficacy and safety of nicorandil combined with trimetazidine hydrochloride in the treatment of microvascular angina. Methods: 518 cases of patients with microvascular angina pectoris from January 2013 to January 2017 in Shaanxi Provincial People’s Hospital were selected as the study subjects. According to the admission sequence, they were divided into the control group and the study group by a random number table method, 260 patients in the control group were treated with trimetazidine hydrochloride, and 258 patients in the study group were treated with nicorandil on the basis of control group. The total clinical efficacy,endothelial vascular function and incidence of adverse reactions were compared between the two groups of patients. Results: After treatment, the total effective rate of study group was 88.76%(229/258), it was higher than that of the control group[62.69%(163/260)](P<0.05); no significant difference was found in the Nitric oxide(NO), endothelin(ET-1), and C-reactive protein(CRP) levels were before treatment between the two groups(P>0.05); after treatment, the CRP and ET-1 levels of both groups of patients were lower than those before treatment, they were lower in the study group than those of the control group(P <0.05); the NO levels of both groups of patients were higher than those before treatment, and it was higher in the study group than that of the control group(P <0.05); the incidence of total adverse reactions in the control group after treatment was 9.23%(24/260), and no difference was found in comparison to that of the study group[10.85%(28/258)](P> 0.05). Conclusion: Nicorandil combined with trimetazidine hydrochloride had better efficacy in the treatment of microvascular angina pectoris, it can significantly improve the endothelial vascular function of patients with equal safety to trimetazidine hydrochloride alone. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)