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[Objective] The aims of this study are to investigate the regularities of runoff and sediment yield on the slope of Dicranopteris pedata under different dead rates (100%, 50% and 0%）, and to reveal the effect of Dicranopteris pedata under different growth conditions on soil erosion control. [Methods] The variation characteristics of runoff and sediment yield on the slope with different dead rates of Dicranopteris pedata were quantitatively analyzed through artificial simulated rainfall experiments. [Results] (1) The runoff rate under different rainfall intensity and dead rate of Dicranopteris pedata increased slowly or rapidly in the early stage, and tended to be stable in the late stage. Under the light rainfall intensity, the erosion rate, except for bare slope, increased slowly in the early stage and tended to be stable in the later stage. Under the high rainfall intensity, the erosion rate increased rapidly in the early stage, and gradually decreased and stabilized in the middle and late stage. (2) Except for the cumulative runoff under 2 mm/min rainfall intensity, the cumulative runoff and sediment yield were significantly different under the other treatment conditions, and the sediment yield increased with the increase of the dead rate of Dicranopteris pedata. (3) The relationship between cumulative runoff and cumulative sediment yield on the slope under different rainfall intensities conformed to the power function model (R~2＞0.99）. [Conclusion] The runoff rate and erosion rate increased rapidly in the early stage and fluctuated steadily in the later stage with the change of rainfall duration under the different mortality rates of Dicranopteris pedata plantation with two kinds of rainfall intensities. A good regression effect is obtained by fitting the functional relationship between cumulative runoff and cumulative sediment yield under each treatment. It is proved that the dead Dicranopteris pedata can also play a good role in soil and water loss control in the red soil erosion area in southern China. [ABSTRACT FROM AUTHOR]

Epilepsy is one of the five major neuropsychiatric diseases that the World Health Organization (WHO) focuses on prevention and treatment. From June 2017 to the present, the Epilepsy Working Group of National Center for Healthcare Quality Management in Neurological Diseases has launched the national epilepsy medical quality indicator system after three batches of pilots, based on full reference to domestic and overseas evidence-based evidence and previous indicator experience. It has built a medical quality control system for epilepsy and convulsive status epilepticus covering 130 sentinel hospitals in 31 provincial administrative regions across China. Regarding on the diagnosis and treatment indicator data feedback from sentinel hospitals, the system was revised based on the published quality control indicators. Twenty validated indicators in epilepsy and convulsive status epilepticus were included. In 2020, the General Office of the National Health Commission issued the indicator system. Disease quality control indicators rely on the national quality control network system to implement medical quality control and management, aiming at improving medical quality and promoting the homogenization of diagnosis and treatment. Currently, this indicator system has been incorporated into the accreditation standards for tertiary hospitals. In addition to strengthening the training, analysis and feedback of information on the indicators, the standardized diagnosis and treatment of epilepsy and convulsive status epilepticus in medical institutions at all levels are constantly promoted. [ABSTRACT FROM AUTHOR]

Epilepsy is one of the five major neuropsychiatric diseases that the World Health Organization focuses on. There are more than 10 million people with epilepsy in China, which lead to tremendous burden of disease. Fortunately, over 70% of epilepsy patients can achieve the treatment goal of seizure control and reintegration into society under standardized treatment. Improving the qualityof diagnosis and treatment of epilepsy can effectively improve the accessibility of medical care in people with epilepsy in China. In 2017, with the support of the National Health Commission, the National Center for Healthcare Quality Management in Neurological Diseases set up the Epilepsy Medical Working Group to start the construction of the medical quality control system in epilepsy and convulsive status epilepticus. The construction of medical quality control system for epilepsy and convulsive status epilepticus strengthened the national epilepsy management system, found out the status of diagnosis and treatment in China, built a dynamic feedback mechanism for the medical quality system with multiple data sources complementing each other. Applying medical quality tools for epilepsy and convulsive status epilepticus, which have continued to promote the homogenization of epilepsy diagnosis and treatment in China. [ABSTRACT FROM AUTHOR]

Objective To study clinical effect of Peiyuan Xiaozheng Formula (Original Qi-Nourishing and Abdominal Mass-Eliminating Formula, PYXZF) on bone pain in patients at chronic kidney disease stage 5 dialysis (CKD 5D) complicated with chronic kidney disease-mineral and bone disorder (CKD-MBD), presenting the patterns of spleen-kidney deficiency and toxin stasis. Methods A total of 76 CKD 5D patients complicated with CKD-MBD bone pain, presenting patterns of spleen kidney deficiency and toxin stasis, were selected from hemodialysis center of Chongqing Hospital of Traditional Chinese Medicine from October 2018 to May 2020.They were randomly divided into control group (CG) (n=30) and experimental group (EG) (n=46). In 12 weeks, CG was given symptomatic treatment, while EG was given an additional PYXZF. The changes of traditional Chinese medical (TCM) pattern scores, visual analogue scale (VAS), serum calcium (Ca), phosphorus (P), parathyroid hormone (iPTH) and serum bone specific alkaline phosphatase (BAP) were observed before treatment, as well as after treatment. Results The total effective rates of CG and EG were 60.71% and 90.9% respectively. The clinical efficacy of EG was better than that of CG (P＜0.01). After treatment, the scores of pattern in EG were significantly lower than those before treatment (P＜ 0.05, P＜0.01). The scores of edema, lack of appetite, loose stool, nausea and vomiting, heavy cumbersome limbs, chest pain and wheezing, pruritus in CG were decreased (P＜0.05, P＜0.01). Compared with those before treatment, VAS scores of EG decreased after 8 weeks and 12 weeks of treatment (P＜0.05, P＜0.01). The VAS scores of CG decreased after 12 weeks of treatment (P＜0.05). Compared with that before treatment, serum Ca in EG was increased (P＜0.01), and serum P, BAP and iPTH were decreased (P＜0.05, P＜0.01) after 8 weeks of treatment. Furthermore, serum Ca still was increased (P＜0.01), and serum P, BAP and iPTH were decreased (P＜0.01) in EG after 12 weeks of treatment. Serum Ca of CG was increased (P＜0.05), serum P, BAP and iPTH were decreased (P＜0.05) after 12 weeks of treatment. Conclusion PYXZF can effectively improve CKD-MBD bone pain in CKD 5D patients. The mechanism may be related to the regulation of abnormal mineral and bone metabolism and the improvement of excessive bone turnover caused by secondary hyperparathyroidism. [ABSTRACT FROM AUTHOR]

Objective To study and compare the oral microbiota and metabolites of children with Henoch Schonlein purpura（HSP） to identify specific microbiota and metabolites related to this disease and elucidate the pathogenesis of HSP. Methods Three groups of qualified subjects were included, including 20 in the HSP group, 20 in the HSP nephritis （HSPN） group, and 20 in the control group. Perform high⁃throughput 16S rRNA sequencing and metabolic profiling of saliva from each group to analyze the correlation between differential microbiota and differential metabolites. Results （1） Compared with the control group, there was a significant difference in richness and diversity in the HSPN group （P < 0.05）. At the same time, there was no significant difference in richness and diversity in the HSP group （P > 0.05）. Compared with the HSP group, the abundance, and diversity of the HSPN group were significantly increased （P < 0.05）. At the genus level, the proportion of Streptococcus in each group is the highest. Compared with the control group, there was no significant correlation between the HSP group and the genus of bacteria. In contrast, the HSPN group showed a significant increase in the genera of Pseudomonas and Parabacteroides （P < 0.05）. Compared with the HSP group, the abundance of Pseudomonas and Parabacteroides in the HSPN group was significantly increased （P < 0.05）.（2） Compared with the control group, the HSPN group had 12 differential metabolites involving nine metabolic pathways, such as phenylalanine metabolism； There was no significant difference in metabolites and no metabolic pathway in the HSP group. Compared with the HSP group, the HSPN group has 15 differential metabolites involving nine metabolic pathways, such as phenylalanine metabolism.（3） In the HSPN and control groups, Pseudomonas and Parabacteroides negatively correlated with Phenylalanine metabolic pathway products. In the HSPN and HSP groups, Pseudomonas, Parabacteroides, and Phenylalanine metabolic path⁃ way products were negatively correlated. The metabolites involved in phenylalanine metabolism in the oral cavity are 2⁃hydroxycinnamic acid， Phenylpyruvic acid, and N⁃acetyl⁃L⁃phenylalanine. Conclusion There is a significant difference between HSPN and HSP children and healthy children. Streptococcus, Pseudomonas, and Parabacteroides may be one of the trigger factors of HSPN, and Phenylalanine metabolism may be one of the pathways in the patho⁃genesis of HSPN. Children with HSPN have a more pronounced imbalance in oral microbiota and greater differences in metabolic products than children with HSP. [ABSTRACT FROM AUTHOR]

Objective To observe the influence of Peiyuan Tongluo Fang (Qi-tonifying Collateral-dredging Decoction, PTF) on clinical efficacy and micro-inflammation state in patients with phase IV diabetic kidney disease (DKD), and investigate the mechanism of PTF in treatment of DKD. Methods Phase IV DKD patients (n=106) were randomly divided into treatment group and control group (each n=53). There were actually 98 patients had complete treatment in 2 groups (each n=49). Besides of basic therapy, the treatment group was treated with PTF, and control group was treated with Niaoduqing Granule for 8 weeks. The changes of TCM patterns and levels of serum creatinine (SCr), estimated glomerular filtration rate (eGFR), 24 h urinary protein excretion (24 h U-pro), urinary microalbumin protein (U-Alb), high sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were observed and analyzed statistically in two groups. Results After treatment, all TCM patterns were significantly relieved (P<0.05 or P<0.01) in treatment group compared with before, which were superior to those in control group (P<0.05 or P<0.01). After treatment, levels of SCr, 24 h U-pro and U-Alb decreased significantly (P<0.01) and eGFR level increased (P<0.05) in treatment group compared with before treatment, which were superior to those in control group (P<0.05 or P<0.01). After treatment, levels of hs-CRP, TNF-α and IL-6 decreased significantly (P<0.01) in treatment group compared with before treatment, which were superior to those in control group (P<0.05). The total effective rate was 73.47% (36/49) in treatment group, and 44.90% (22/49) in control group (P<0.05). No adverse reactions were observed in 2 groups. Conclusion PTF combined with basic therapy of Western medicine can effectively reduce urine protein, protect kidney and alleviate micro-inflammation state in patients with phase IV DKD. [ABSTRACT FROM AUTHOR]

The two-wheel self-balancing vehicle system is a system which is similar to an inverted pendulum, and holds multivariable, nonlinear, strong coupling characteristics. For the complexity of the vehicle control system, we designed a self-balancing vehicle system by using STM32F103C8T6 microprocessor as the main controller, and MPU-6050 sensor as the attitude detection unit. Because gyroscope and accelerometer exist measurement noise and random drift error, Kalman filter algorithm is used to realize data fusion of the gyroscope and the accelerometer. In this way the sensor measurement error is compensated and the best estimates of the vehicle inclination and angular velocity are obtained. A double closed loop control is established with the feedback of optimal attitude angle and vehicle speed. PID control is used to achieve self-balancing control of the vehicle system. The hardware and software are also designed. By commissioning and operation the self-balancing vehicle can achieve stable self-balancing control. [ABSTRACT FROM AUTHOR]

The development of shale oil has relieved the tense situation of energy supply in China, and it's an important energy for sustainable development. The main develop method for Chang 7 shale oil is depletion, resulting in rapid production decline and low recovery factor. There is a large energy deficit in the formation for long-term primary development, so it is urgent to supply the formation pressure for further development. In order to explore a effective way to supplement pressure and enhance oil recovery, based on a shale oil block in Changqing oilfiled, experiments were conducted to compare the properties of different kinds of gas and crude oil systems, and a field-scale numerical simulation was performed to optimize the parameter of associated gas huff-n-puff. The optimum parameters are gas injection volume 90 × 10 4 m 3, injection rate 3 × 10 4 m 3 / d, 20 d of soaking time, 10 cycles of huff and puff. On the basis of overall unified optimization, gas injection volume optimization for a single well is conducted and the optimum volume is increased to 150 × 10 4 m 3, which is further improving the oil increase effect of gas injection huff-n-puff. The cumulative oil production volume of huff-n-puff increases 33% than that of depletion. The research results explore an effective way for energy supplement and enhancing shale oil recovery, and provide a support for possible field application of associated gas injection huff-n-puff in Changqing shale oil. [ABSTRACT FROM AUTHOR]

In the construction of mountain tunnels and underground projects, most of them will pass through weak layers such as weak interlayers or broken zones. The geometric shape of this kind of weak stratum changes greatly, the mechanical properties are poor, and the convergent deformation after tunnel excavation is often difficult to control. This has also become the difficulty of mountain tunnel construction and structural design. The law of the influence of the weak stratum dip on the excavation deformation of the surrounding rock of the tunnel is the object of study, the vault and arch waist of soft and weak layer surrounding rock under unsupported conditions were the studied parts through model experiments. The convergence deformation caused by tunnel excavation was monitored for soft layer inclination angles of 45°, 60°, 90°, 120° and 135° respectively. Combined with numerical simulation methods, the detection rules of the model test were further verified by comparison. The results show that tunnel surrounding rock deformation is very significantly affected by the soft layer dip angle. The surrounding rock displacements of the tunnel vault, vault waist and invert arch decrease first and then increase with the increase of the inclination of the weak layer. The results of numerical calculations and model tests for the change of surrounding rock displacement at the arch top and arch waist positions show a high degree of consistency at different inclination angles by normalization. And the area of shear damage is continuous, distributed in a week of the tunnel, its area with the soft layer dip angle increases, first decreasing and then increasing through the monitoring surface of the plastic zone cloud map. [ABSTRACT FROM AUTHOR]

Objectives: On January 8th 2022, an Ms 6.9 earthquake struck Menyuan, Qinghai Province, China. The epicenter is located in the middle section of Qilian-Haiyuan fault in the northeast margin of the Tibetan Plateau, which is a seismic gap. It is of great significance to study this earthquake for under-standing the tectonic deformation mechanism, strain release process and seismic hazards of the NE Tibetan Plateau.Methods: Differential synthetic aperture radar interferometry (D-InSAR) is used to obtain the coseismic deformation along the line of sight (LOS) of the Menyuan earthquake from Sentinel-1 satellite images. The co-registration of optically sensed images and correlation are used to obtain the EW coseismic deformation from the multi-temporal Sentinel-2 data. Based on the coseismic deformation field derived from InSAR interferograms, we invert the slip distribution. Results: The LOS deformation fields showed that the Menyuan earthquake caused a surface rupture of about 20 km long and the maximum LOS displacement was 0.75 m. The maximum EW displacement derived from optical images was 2.5 m. The slip distribution model showed that the Menyuan earthquake was dominated by a sinistral strike-slip. The coseismic slip is concentrated at a depth of 0 - 10 km. The maximum slip was 3.25 m at a depth of 4.89 km and the rake angle was 10.44°. The estimated total seismic moment is 1.07x1019 N.m, corresponding to a magnitude of Mw 6.6. Conclusions: According to the results from aftershock relocation, field investigation and tectonic background, we infer that the seismogenic fault is the Lenglongling fault and the eastern segment of Tuolaishan fault is also ruptured. The stress on the eastern segment of the Lenglongling fault and the western segment of the Tuolaishan fault is enhanced, implying that there is the possibility of strong earthquakes in this region in the future. [ABSTRACT FROM AUTHOR]

In received signal strength indication (RSSI)⁃based positioning, the deployment structure of bea⁃ con nodes greatly affects the accuracy of positioning. In theory, the intensive and well⁃proportioned distribu⁃ tion of these deployed can insure the high precise positioning results. However, the RSSI is seriously dis⁃ turbed by noise in the actual environment, which makes it difficult to ensure stable signal propagation even if the layout is reasonable. In addition, dense deployment can lead to crosstalk between signals, and com⁃ plex physical environments make it difficult to achieve ideal deployment of beacon nodes, which greatly af⁃ fects the positioning result. In this paper, we propose an algorithm for optimal selection of beacon nodes in trilateration positioning. After beacon deployment, the optimal reference beacon combination for each local region in the positioning scene is constructed according to the geometric relationship of the beacon nodes. Then, the beacon sequence scanned by the device in real time is matched with the regional best beacon com ⁃ bination. The preferred beacon nodes are used to solve the position, and the positioning accuracy is improved by optimally selecting the reference beacon nodes. Experiments show that the proposed algorithm can im ⁃ prove the positioning accuracy efficiently, which is close to the result of selecting the best reference beacons. [ABSTRACT FROM AUTHOR]