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新型时域混合调制（TDHM）技术可以提高光通道的频谱使用效率,有效地提高光网络的容量。针对共享备份路径保护（SBPP）技术下的波分复用（WDM）光网络,我们结合TDHM技术研究了路由和波长分配（RWA）问题,并提出了一种基于最佳路径对策略的优化技术。仿真结果表明,与传统的最短路径策略优化技术相比,提出的最佳路径对策略能使被保护的网络容量提高30%,从而验证了TDHM技术对提高光网络传输容量的有效性。

ROADM（可重构的光分插复用器）是构建大型全光交换网络的核心设备。目前,大部分商用ROADM支持无色和无向性,但无阻塞性由于其高成本仍无法广泛应用,因此有效降低光通信业务的阻塞率是当前亟待解决的问题。文章基于具有多个上下路端口模块的有阻塞ROADM节点架构,提出了三种RWA（路由和波长分配）算法,以有效提高光通道业务的阻塞性能。仿真结果表明,结合上下路端口状态的波平面算法能有效地降低光通道业务的阻塞率。

网络可用性是业界SLA（服务等级协议）的重要指标之一,提高光网络可用性是当今ISP（网络服务供应商）面临的现实问题,同时也是国内外学术界研究的热点。文章在现有波分复用光网络研究的基础上,利用Java语言编写启发式算法,提出基于M∶N保护技术的可用性分析模型。结果表明,M∶N保护技术可以很大程度地提高光网络可用性,链路保护技术较路径保护技术以耗费预留网络资源为代价可以获得更高的可用性。

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Polymer Materials Science & Engineering is the property of Sichuan University, Polymer Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Water Conservancy & Electric Power Technology & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Earthquake Sciences is the property of China Earthquake Administration, Institute of Geophysics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The basement membrane is a specialized extracellular matrix between the epithelium and the mesenchyme. In stratified epithelium, only the basal cells in contact with the basement membrane exhibit the apical-basal polarity, whereas the epithelial cells do being not in contact with the basement membrane do not exhibit the apical-basal polarity. The basement membrane plays an important role in epithelial cell polarization. It is an important extracellular matrix (ECM) structure in the multicellular organisms, is situated between the epithelium and the mesenchyme, and is produced jointly by the epithelial cells and mesenchymal cells. Its components mainly include Laminin, type Ⅳ collagen (Col-Ⅳ), nidogen(NDG), and heparan sulfate proteoglycans (HSPG), and each component plays the different role in influencing the epithelial cell polarity. The network scaffold formed by Col-Ⅳ and Laminin is the main structure of the basement membrane, and the integrity of the structure affects the epithelial cell polarization. This review summarizes the composition and structure of the basement membrane, focuses on its role in epithelial cell polarization and its mechanism, and compiles the current status of biomimetic basement membrane materials that promotes the epithelial cell polarization, and provides the theoretical foundation for further exploration of the establishment and maintenance of epithelial cell polarity. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective·To study the effect of phosphatase and tensin homolog on chromosome 10 (PTEN) on alternative splicing of forkhead box M1 (FoxM1), and its impact on tumor cell migration. Methods·PTEN was knocked down by short hairpin RNA (shRNA) in human embryonic kidney 293T cells, human prostate cancer DU145 cells, human colorectal adenocarcinoma RKO cells, and human colon cancer SW480 and SW620 cells. Specific primers were designed for FoxM1 and its subtypes FoxM1B and FoxM1C, and the mRNA expression levels of FoxM1B and FoxM1C were detected by quantitative real-time PCR (qRT-PCR). FoxM1B and FoxM1C were overexpressed in DU145 cells, and their effects on tumor cell migration were tested by Transwell assay and wound healing assay. Immunofluorescence and dual luciferase reporter gene assay were used to explore the potential mechanism of differential regulation of tumor cell migration by FoxM1B and FoxM1C. Results·① PTEN was knocked down in 293T, DU145, RKO, SW480, and SW620 cell lines. qRT-PCR results showed that compared with the control cells, the mRNA expression level of FoxM1B significantly increased in PTEN knockdown cells, while the mRNA expression level of FoxM1C decreased or remained unchanged. Knockdown of PTEN did not affect the transcription level of FoxM1, but caused the variable splicing of FoxM1 and promoted the generation of FoxM1B. ② Compared with the control cells, the number of DU145 cells migrating to the below chamber increased in the FoxM1B overexpression group (P=0.024), while the number of migrating DU145 cells in the FoxM1C overexpression group was lower (P=0.000). The healing ability of DU145 cells was significantly enhanced in the FoxM1B overexpression group (P=0.001), while the healing ability of DU145 cells was weakened in the FoxM1C overexpression group (P= 0.021). Overall, FoxM1B and FoxM1C had opposite effects on tumor cell migration. FoxM1B promoted tumor cell migration, while FoxM1C inhibited tumor cell migration. ③ Neither FoxM1B nor FoxM1C overexpression could induce β -catenin to enter the nucleus. Dual luciferase reporter gene assay showed no difference in the transcriptional activity of FoxM1B and FoxM1C. The difference between FoxM1B and FoxM1C in the regulation of tumor metastasis was also not mediated by β-catenin translocation. Conclusion·Knockdown of PTEN regulates the alternative splicing of FoxM1, leading to increasing expression of transcript FoxM1B, which plays a positive role in tumor cell migration. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Laser Technology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tianjin Medical Journal is the property of Tianjin Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To probe into the efficacy of compound Zaofan pills combined with recombinant human granulocyte colony-stimulating factor (rhG-CSF) in the treatment of leukopenia after tumor chemotherapy. METHODS: A total of 94 patients with leukopenia after tumor chemotherapy admitted into the hospital in 2021 were extracted to be divided into the control group and the observation group via the random number table method, with 47 cases in each group. The control group received rhG-CSF treatment, while the observation group was given compound Zaofan pills combined with rhG-CSF treatment. The clinical efficacy, traditional Chinese medicine syndrome score, incidence of adverse drug reactions, peripheral blood white blood cell (WBC) count, neutrophil count (NEUT), CD3 +, CD4 +, CD8 + and CD4 + / CD8 + were compared between two groups. RESULTS: The total effective rate of the observation group was 89. 36% (42 / 47), significantly higher than 72. 34% (34 / 47) of the control group, the difference was statistically significant (P<0. 05). After treatment, the traditional Chinese medicine syndrome score and peripheral blood CD8 + levels decreased significantly, while peripheral blood WBC, NEUT, CD3 + , CD4 + and CD4 + / CD8 + levels increased significantly in two groups; the traditional Chinese medicine syndrome score and peripheral blood CD8 + levels of the observation group were significantly lower than those of the control group, and the peripheral blood WBC, NEUT, CD3 +, CD4 + and CD4 + / CD8 + levels of the observation group were significantly higher than those of the control group, the differences were statistically significant (P<0. 05). The incidence of adverse drug reactions in the control group and the observation group were respectively 17. 02% ( 8 / 47) and 12. 77% ( 6 / 47), and there was no significant difference between two groups (P>0. 05). CONCLUSIONS: The efficacy of Zaofan pills combined with rhG-CSF in the treatment of leukopenia after tumor chemotherapy is significant, which can effectively increase the WBC and improve the immune function with higher safety. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China / Zhongguo Yiyuan Yongyao Pingjia yu Fenxi is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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