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Objective To explore the relationships between blood phosphorus and parathyroid hormone (PTH) levels and the sleep disorders in patients undergoing maintenance hemodialysis (MHD) . Methods Totally 100 patients undergoing maintenance hemodialysis were enrolled. Patients were divided into two groups according to the Pittsburg Sleep Quality Index (PSQI) scale: the good sleepers (n=29) and poor sleepers (n=71) . Clinical data were compared between two groups, and Logistic regression analysis was performed to identify the effects of blood phosphorus and PTH on sleep disorders among MHD patients. The predictive value of blood phosphorus and PTH for sleep disorders in MHD patients was evaluated by the receiver operating characteristic (ROC) curve. Results The blood phosphorus and PTH levels were significantly higher in the poor sleepers than in the good sleepers (both P<0. 05) . Hyperphosphatemia (OR=3. 85, 95% CI= 1. 496-9. 908) and elevated PTH (OR=1. 003, 95% CI=1. 001-1. 006) were independent risk factors for sleep disorders in MHD patients (both P<0. 05) . After adjusting gender and age, for every 1 mmol/L increase in blood phosphorus, the risk of sleep disorders increased by 4. 082 times; for every 1 pg/mL increase in PTH, the risk of sleep disorders increased by 1. 004 times. The area under the ROC curve of blood phosphorus and PTH in prediction of sleep disorders in MHD patients was higher than that of either alone (both P<0. 05) . Conclusion MHD patients with hyperphosphatemia and elevated PTH were prone to sleep disorders, and the combination of blood phosphorus and PTH had certain predictive value for the occurrence of sleep disorders in MHD patients. [ABSTRACT FROM AUTHOR]

Objective To understand the adverse childhood experiences of middle school students in Huangpu District and the association and gender differences between sleep disorders, and to provide scientific basis for the prevention and control policies of sleep disorders. Methods A stratified cluster sampling method was used to investigate the adverse childhood experiences (ACEs) of middle school students, evaluate their overall sleep function, and investigate the childhood adverse experiences of 6 middle school students in Huangpu District. The detection rate of sleep disorders in different childhood adverse experiences exposure was compared using a chi square test. A binary logistic regression model was established to analyze the risk and gender differences between exposure to adverse childhood experiences and sleep disorders in middle school students. Results This study analyzed a total of 6 710 students from 6 high schools in Huangpu District, Guangzhou, with 3 525 males and 3 185 females. The detection rate of sleep disorders was 18.0%. The detection rate of ACEs ranged from 1.3% (substance abuse among family members) to 38.9% (domestic violence). The results of the multivariate binary logistic regression analysis showed that, except for the parental disability dimension, the risk of developing sleep disorders was increased in subjects with ACEs (OR=1.38-4.58). There was a dose-response relationship between the cumulative number of ACEs and the risk of sleep disorders. In addition, the risk intensity between emotional neglect and sleep disorders was significantly higher in girls than in boys, but there was no interaction between gender and the association between other types of ACEs or the cumulative number of ACEs and sleep disorders. Conclusion There is a significant association between ACEs exposure and sleep disorders among middle school students in Huangpu District, the incidence of sleep disorders in girls is higher than that in boys, and girls who were emotionally neglected during childhood have a higher risk of developing sleep disorders. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the causal association of liver function and lipid metabolism levels with sleep disorders based on the Mendelian randomization analysis. Methods The analysis was conducted using the data from genome-wide association studies, with the exposure factors of liver function and lipid metabolism levels (alanine aminotransferase [ALT], aspartate aminotransferase [AST], gamma-glutamyl transpeptidase [GGT], albumin [Alb], serum total protein [TP], total bilirubin [TBil], alkaline phosphatase [ALP], triglyceride [TG], triglyceride-to-glycerol-3-phosphate [TG/G3P] ratio, total cholesterol [TC], high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], poly-unsaturated fatty acids [PUFA], total fatty acids [TFA], PUFA/TFA ratio) and the outcome factor of sleep disorders (nonorganic) . The regression models including inverse variance weighted, MR-Egger, Simple mode, weighted median, and Weighted mode were used to perform the Mendelian randomization analysis. Results Serum Alb (odds ratio [OR] =0.728, 95% confidence interval [CI] : 0.535 — 0.989, P<0.05), HDL-C (OR=0.879, 95%CI: 0.784 — 0.986, P< 0.05), and PUFA/TFA ratio (OR=0.800, 95%CI: 0.642—0.998, P<0.05) were negatively associated with sleep disorders, while TG/G3P ratio (OR=1.222, 95%CI: 1.044—1.431, P<0.05) was positively associated with sleep disorders. The results of Mendelian randomization did not show a causal association of ALT, AST, GGT, TP, TBil, ALP, TG, TC, LDL-C, PUFA, and TFA with sleep disorders (all P>0.05) . The results of the MR-Egger intercept test showed no pleiotropy (P>0.05), and Mendelian randomization was a valid method for causal inference in this study. Conclusion According to the results of the Mendelian randomization analysis, liver function and lipid metabolism show significant association with sleep disorders. Liver function and lipid metabolism can be used as indicators for predicting the risk of sleep disorders and performing intervention. [ABSTRACT FROM AUTHOR]

Stroke, as a neurological disease characterized by high disability and mortality rates, poses a significant threat to the long-term quality of life for patients. Effective neurofunctional rehabilitation measures can substantially mitigate the long-term disabilities induced by stroke. Motor relearning, a crucial mechanism in post-stroke rehabilitation, is heavily reliant on good sleep quality. However, stroke patients often suffer from sleep disorders, which have a non-negligible negative impact on rehabilitation outcomes. This paper delved into the bidirectional relationship and pathophysiological mechanisms between sleep disorders and stroke rehabilitation. It also reviewed the application and prospect of emerging technologies such as non-invasive/invasive brain stimulation, virtual reality therapy, wearable sleep tracking devices, and gene therapy in stroke patients with sleep disorders, aiming to provide new perspectives and effective methods for optimizing stroke rehabilitation strategies, so as to enhance the rehabilitation effects and quality of life for stroke patients. [ABSTRACT FROM AUTHOR]

目的 分析2013—2023年缺血性卒中和睡眠相关性研究的现状及研究热点。 方法 在Web of Science核心合集中检索2013年1月1日—2023年12月31日缺血性卒中和睡眠相关性研究的文献。使用RStudio的bibliometrix软件包和VOSviewer软件对该领域研究的发文量、国家/地区、机构、作者、期刊、文献引用、关键词和研究热点进行分析，并进行可视化呈现。 结果 共检索到798篇文献。以通信作者分析，中国发文199篇，居全球首位，且与多个国家建立了合作关系。美国发文196篇，位列第2。发文量最多的机构是加拿大多伦多大学，共34篇。发文量前10位的作者中5位来自美国密歇根大学，相互合作较密切，其中美国学者Devin L Brown发表文章数量为28篇，被引频次236次，发文量和被引频次均居首位。发文量最多的期刊是Sleep Medicine（74篇），发表文章被引频次最高的期刊是Stroke（3542次）。关键词可视化分析发现卒中与睡眠呼吸暂停出现频次最高。在卒中与睡眠相关性研究领域，研究主题分析提示失眠、抑郁作为基础课题对该领域发展非常重要，卒中预防、功能结局、脑血流主题研究需要努力开发。 结论 越来越多的研究聚焦于缺血性卒中和睡眠之间的关联性，中国和美国在该领域发表文献较多，睡眠呼吸障碍是主要研究热点。未来在卒中和睡眠领域可探索失眠、抑郁、卒中预防、功能结局、脑血流等主题。 Abstract: Objective To analyze the current status and research hotspots of research on the correlation between ischemic stroke and sleep from 2013 to 2023. Methods A literature search was conducted in the Web of Science core collection for articles related to ischemic stroke and sleep published between January 1, 2013, and December 31, 2023. The bibliometrix package in RStudio and VOSviewer software were utilized to analyze and visualize the number of published studies, contributing countries/regions, institutions, authors, journals, citations, keywords, and research hotspots in this field. Results A total of 798 articles were retrieved. An analysis of corresponding authors revealed that China ranked first globally with 199 publications and established collaborations with multiple countries. The United States followed closely with 196 publications. The University of Toronto (Canada) was the leading institution with 34 publications. Among the top ten authors, five were from the University of Michigan (US), and they had close cooperation with each other. American scholar Devin L Brown published 28 articles and was cited 236 times, ranking first in the number of articles published and the frequency of citations. Sleep Medicine published the most articles on ischemic stroke and sleep (74 articles), while Stroke had the highest citation frequency (3542 times). Through the visual analysis of keywords, it was found that stroke and sleep apnea had the highest occurrence frequency. In the research field of the correlation between stroke and sleep, the analysis of research themes suggests that insomnia and depression are fundamental topics crucial to the development of this field. Stroke prevention, functional outcomes, and cerebral blood flow are potential themes that require further exploration. Conclusions An increasing number of studies have focused on the correlation between ischemic stroke and sleep. China and the United States have published more literature in this field, and sleep-disordered breathing is the major research hotspot. Future research in the field of stroke and sleep should explore themes such as insomnia, depression, stroke prevention, functional outcomes, and cerebral blood flow.

目的 初步探明以无卒中型烟雾病为代表的慢性脑缺血患者的睡眠质量及影响因素，分析睡眠质量与术后缺血症状和卒中的相关性。 方法 前瞻性纳入138例经影像学确认的无卒中型烟雾病患者，收集患者的性别、年龄、首发症状、合并基础疾病等临床资料。使用匹兹堡睡眠质量指数量表评估患者的术前睡眠质量，使用HAMD-17和MoCA分别评估患者的术前抑郁状态和认知功能。比较睡眠质量正常组和睡眠质量下降组患者的临床特征、认知功能与抑郁状态，使用多因素logistic回归分析影响患者睡眠质量的危险因素，并对接受脑血管重建术治疗的患者进行随访，分析两组患者术后缺血症状发作、卒中发生率的差异。 结果 共52例（37.7%）烟雾病患者存在睡眠质量下降。睡眠质量下降组患者较睡眠质量正常组具有更高的年龄（P=0.002）、更差的认知功能（P=0.017）和更明显的抑郁倾向（P=0.012）。多因素logistic回归分析结果显示，年龄（OR 1.05，95%CI 1.01～1.09，P=0.021）和HAMD-17评分（OR 1.11，95%CI 1.01～1.23，P=0.035）是患者睡眠质量下降的独立危险因素。在术后随访中，术前存在睡眠质量下降的患者有更高的缺血症状发生率（P=0.008）。两组患者术后新发卒中率差异无统计学意义。 结论 无卒中型烟雾病患者存在较高比例的睡眠障碍，且与患者术后缺血事件发生相关，在临床诊疗中应加强对烟雾病患者睡眠质量的评估和干预。 Abstract: Objective To explore the sleep quality and influencing factors in patients with chronic cerebral ischemia represented by Moyamoya disease without stroke, and analyze the correlation between sleep quality and postoperative ischemic symptoms and stroke. Methods A total of 138 Moyamoya disease patients without stroke confirmed by imaging were prospectively included, and clinical data including gender, age, initial symptoms, and comorbidities were collected. The Pittsburgh sleep quality index scale was used to assess the patient’s preoperative sleep quality, and the HAMD-17 and MoCA were used to evaluate preoperative depression status and cognitive function, respectively. Clinical characteristics, cognitive function, and depression status were compared between the normal sleep quality group and the decreased sleep quality group. Multivariate logistic regression analysis was used to analyze the risk factors affecting patient’s sleep quality. Patients who underwent cerebral revascularization were followed up to determine the differences in the incidence of postoperative ischemic events and stroke between the normal and decreased sleep quality groups. Results A total of 52(37.7%) patients with Moyamoya disease experienced decreased sleep quality. Patients with decreased sleep quality were older (P=0.002), had poorer cognitive function (P=0.017), and exhibited more significant depressive tendencies (P=0.012) than those with normal sleep quality. Multivariate analysis suggested that age (OR 1.05, 95%CI 1.01-1.09, P=0.021) and HAMD-17 score (OR 1.11, 95%CI 1.01-1.23, P=0.035) were independent risk factors for decreased sleep quality. Additionally, during the postoperative follow-up, patients with a preoperative decrease in sleep quality had a higher incidence of ischemic symptoms (P=0.008). There was no significant difference in stroke recurrence rates between the two groups. Conclusions Patients with Moyamoya disease without stroke have a higher proportion of sleep disorders, which are associated with postoperative ischemic events, highlighting the need for enhanced assessment and intervention of sleep quality in clinical practice.

The incidence of decreased ovarian reserve (DOR) is gradually increasing, with fluctuations in hormone levels causing a series of clinical syndromes. Among these, sleep disorders stand out as prominent symptoms, clinically manifested by difficulties in falling asleep, shortened sleep duration, and poor sleep quality, severely impacting the physical and mental health as well as the quality of life of women. Clinical observations have found a close relationship between decreased ovarian reserve and sleep disorders, where the two interact causally and reciprocally. Western medicine primarily focuses on improving behavioral cognition, administering sedatives and hypnotics, and hormone replacement therapy, albeit with certain limitations in efficacy. Traditional Chinese medicine emphasizes holistic views and syndrome differentiation in treatment, offering low side effects and unique advantages. This review summarizes recent literature on the research progress of sleep disorders and DOR from both Western and traditional Chinese medicine perspectives, providing reference for clinical treatment. [ABSTRACT FROM AUTHOR]

Objective: To observe the occurrence of sleep disorders in elderly patients with chronic obstructive pulmonary disease (COPD) and its correlation with cognitive impairment. Methods: A total of 100 elderly patients with COPD admitted to the hospital from January 2021 to December 2022 were selected. According to the Pittsburgh Sleep Quality Index (PSQI) score, the subjects were divided into sleep disorder group and non-sleep disorder group. Cognitive function in the two groups was evaluated with the Mini Mental State Examination (MMSE). Baseline data and MMSE scores of the two groups were taken as independent variables. Univariate analysis and multivariate logistic analysis were conducted to identify the influencing factors of sleep disorders. The correlation between PSQI score and MMSE score was analyzed. Results: Of the 100 elderly patients with COPD, 32 (32%) had sleep disorders. Compared with the non-sleep disorder group, the sleep disorder group had higher PSQI scores. The total PSQI score of the sleep disorder group was (7.48± 1.81), higher than (6.02±0.74) of the non-sleep disorder group (P<0.05). Univariate analysis showed that the MMSE scores of different dimensions and the total MMSE score of the sleep disorder group were lower than those of the non-sleep disorder group. The proportions of patients with course of disease ≥ 10 years and dyspnea grade ≥ 3 were higher than those in the non-sleep disorder group (P<0.05). Multivariate logistic regression analysis showed that course of disease, dyspnea grade and MMSE score were independent risk factors for sleep disorders in patients with COPD (P<0.05). Pearson correlation analysis found that PSQI score was negatively correlated with MMSE score in patients with COPD, while the PSQI score is positively correlated with the course of the disease and the grading of dyspnea (P<0.05). Conclusion: The risk of sleep disorders in elderly patients with COPD is high. The course of disease, dyspnea grade, and MMSE score are influencing factors of sleep disorders. In addition, the patients' sleep quality is closely related to the degree of cognitive impairment, which deserves attention in clinical practice. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect of Bailemien capsule combined with Delisin on sleep structure related indexes, sleep quality and neurotransmitter levels in patients with sleep disorders (SD). Methods A total of 98 SD patients treated in our hospital from January 2022 to September 2023 were divided into the control group and the observation group with 49 cases in each group by random number method. The control group was treated with Delisin, and the observation group was treated with Bailimian capsule on the basis of Delisin treatment. The sleep structure related indexes [including sleep onset latency (SOL), total sleep time(TST) and sleep efficiency (SE)], sleep quality [Pittsburgh Sleep Quality Index (PSQI) score,and neurotransmitter levels [including norepinephrine (NE), 5-hydroxytryptamine (5-HT) and gamma-aminobutyric acid (GABA)] were compared between the two groups. Results After treatment, the SOL, PSQI scores and NE levels of the two groups were significantly decreased, TST and SE were significantly increased, 5-HT and GABA levels were significantly increased, and the SOL, TST, SE and PSQI scores, as well as NE,5-HT and GABA levels of the observation group were superior to the control group after treatment. The differences were statistically significant (P<0.05). Conclusion Bailemien capsule combined with Delisin can regulate the level of neurotransmitter in SD patients, improve the related indexes of sleep structure and improve sleep quality. [ABSTRACT FROM AUTHOR]

Sleep disorder refers to abnormal sleep quantity, quality or some clinical symptoms occur during sleep, which seriously affects human function and health. The incidence of sleep disorders is positively correlated with age, and perimenopause in women is usually the turning point of female sleep due to the high incidence of menopause syndrome and metabolic related diseases. Sleep disorders in perimenopausal and postmenopausal women are characterized by difficulties in falling asleep, sleep maintenance disorders, daytime dysfunction, and anxiety and depression in severe cases. According to the related risk factors, symptomatic treatment, alleviate menopause -related symptoms, improve sleep quality, increase effective sleep time, restore social function, and improve the quality of life are the goals of the treating of perimenopausal sleep disorders. Therapeutic measures for perimenopausal and postmenopausal sleep disorders include non-drug therapy (sleep hygiene education, cognitive-behavior therapy for insomnia) and pharmacological therapy (menopausel hormone therapy, psychotropic and sedative hypnotic drugs, melatonin, traditional Chinese medicine, etc.). This article reviews the research progress on the risk factors and diagnosis and treatment of sleep disorders in perimenopausal and postmenopausal women. [ABSTRACT FROM AUTHOR]

目的　观察高原旅居史对急进高原人群适应能力的影响。方法　选择2023年11月—2024年1月急进高 原地区（3 900 m）的青年士兵2 337人，按照高原旅居史次数分为无高原旅居史组（A组，425人）、2 ~ 3次高原旅居史 组（B组，1 534人）、4次及以上高原旅居史组（C组，378人）。三组乘坐汽车由驻地出发上升至海拔3 900 m地区，用 时9 h，中途休整约1 h。分别于三组进入高原前（第0天）及急进高原后第1、7、14天进行急性高原病（AMS）评分，检 测血氧饱和度、心率、红细胞（RBC）、血红蛋白（HGB）、红细胞压积（Hct）、体质量、体脂率，于急进高原第14天进行 匹兹堡睡眠质量指数量表（PSQI）评分。结果　A组急进高原第1、7天AMS评分高于B、C组（P 均<0. 01）。A、B、C 组急进高原第14天AMS发生率依次降低（P 均<0. 01）。A、B、C组急进高原第1、7天血氧饱和度低于第0天，第1、7、 14天心率高于第0天，第7、14天RBC、HGB、Hct高于第0天（P 均<0. 05）；急进高原第1、7天，B、C组血氧饱和度高于 A组，第1天C组血氧饱和度高于B组（P 均<0. 05）；急进高原第7、14天A、B、C组的RBC、HGB、Hct依次增高（P 均 <0. 05）。三组急进高原后体质量和体脂率变化差异均无统计学意义（P 均>0. 05）。急进高原第14天A、B、C组PSQI 总分依次降低，其中日间功能、睡眠效率、睡眠时间、入睡时间、睡眠质量项目得分也依次降低（P 均<0. 05）。结论 多次高原旅居史者较无高原旅居史者急进高原后AMS及睡眠障碍发生率降低，有高原旅居史人群对高原的适应能 力更强。 [ABSTRACT FROM AUTHOR]

Objective To investigate the association of sleep disorders with the development and progression of nonalcoholic fatty liver disease (NAFLD). Methods A total of 1 868 participants from the health examination cohort and fatty liver cohort of Beijing Friendship Hospital from June 2022 to June 2023 were enrolled as subjects. Related data were collected from all subjects. including age, sex, education level, chronic medical history, and biochemical parameters, and all subjects completed Pittsburgh Sleep Quality Index (PSQI) scale independently. According to the diagnostic criteria, the subjects were divided into non-NAFLD group with 1 122 subjects and NAFLD group with 746 subjects, and according to the stage of progression, the patients in the NAFLD group were further divided into simple fatty liver group (SFL group with 624 subjects) and nonalcoholic steatohepatitis (NASH) group with 122 subjects. A one-way analysis of variance or the Kruskal-Wallis H test was used for comparison of continuous data between three groups. The chi-square test was used for comparison of categorical data between the three groups. The binary Logistic regression analysis was used to investigate the association between sleep factors and NAFLD, and the multinomial Logistic regression analysis was used to investigate the association between sleep factors and the different stages of NAFLD; two multivariate models were constructed for adjustment of potential confounding factors, i, e., an age-sex adjustment model and a multivariate adjustment model, and the multivariate adjustment model adjusted the factors of age, sex, education level, smoking, diabetes, hypertension, body mass index (BMI), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). Results There were significant differences in age, sex, BMI, education level, smoking, diabetes, hypertension, alanine aminotransferase, TG. and HDL-C between the non-NAFLD, SFL, and NASH groups (all P<0.05). There were also significant differences between the three groups in the total score of PSQI scale and the proportion of subjects with a score of 0-3 points for the 7 sleep components (all P< 0.05). The multivariate adjustment model showed no significant association between sleep disorders and SFL, while long sleep latency (odds ratio [OR] =4.04. 95% confidence interval [Cl]: 2.33-7.03, P<0.001), short sleep duration (OR=3.53, 95%CI: 1.83-6.82. P<0.001), and severe sleep disorders (OR=2.96, 95%CI: 1.48-5.93, P=0.002) were closely associated with the risk of NASH. Conclusion Overall sleep condition and its components of sleep disorders are not significantly associated with the simple fatty liver; however, long sleep latency, short sleep duration, and severe sleep disorders can increase the risk of NASH, which should be taken seriously in clinical practice. [ABSTRACT FROM AUTHOR]

Objective: To analyze the clinical data of the patients with leucine-rich glioma inactivated 1 (LGI-1) antibody-positive autoimmune encephalitis (AE) (LGI-1 AE) complicated with sleep structure abnormality and cognitive impairment, and to discuss the possible pathogenic mechanism. Methods: A 68-year-old male patient was admitted to our hospital due to memory decline for 2 months and seizures for 1 month. After diagnosed with LGI-1 AE, the patient was treated with intravenous immunoglobulin combined with methylprednisolone sodium succinate, resulting in the improved symptoms. Excluding any pharmaceutical influences, the neuropsychological assessments, including sleep evaluations with polysomnography (PSG), were performed during both the acute phase and the recovery phase. Results: During the acute phase assessment, the patient exhibited severe cognitive impairments, scoring 22 on the Mini-Mental State Examination (MMSE) and 19 on the Montreal Cognitive Assessment (MoCA). The PSG results showed that the total sleep time (265 min) was shortened, the sleep fragmentation throughout could be seen, the sleep efficiency was reduced, and N3 and rapid eye movement (REM) sleep stages were complete absent. In the recovery phase, the patient’s cognitive functions improved (MMSE score was 30, MoCA score was 26), the total sleep time returned to normal with PSG, the sleep onset latency was 13. 5 min, the sleep fragmentation notably improved, the sleep efficiency was increased to 84. 3%, the N3 sleep lasted 26 min (5. 1%), and the REM sleep lasted 69 min (13. 6%). Conclusion: The abnormality in sleep structure and cognitive impairment in the patients with LGI-1 AE are synchronous in onset and outcome, and may be one of the etiologies of cognitive dysfunction in these patients. The pathological origin of the sleep disorder may lie in the hypothalamus. Hypothalamic secretions and the Lhx6 pathway might become new targets for correcting the sleep structure while treating the cognitive impairment. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的　探究睡眠障碍 (SD) 与亚临床甲状腺功能减退 (SCH) 患者发生骨质疏松症的关系. 方法　选取年 龄≥50 岁男性及绝经后女性 SCH 患者 284 例, 收集患者病历资料, 测量腰椎 (LS), 股骨颈 (FN), 全身 (WB) 骨密度 (BMD), 计算T值, 基于BMD分为骨量正常, 骨量减少, 骨质疏松. 用匹兹堡睡眠质量指数 (PSQI) 评分评价睡眠质 量, 根据PSQI评分将SCH患者分为非SD组59例, SD组225例；根据睡眠障碍程度将SD组分为3个亚组 (睡眠轻度 障碍组 91例, 睡眠中度障碍组 80例, 睡眠重度障碍组 54例), 比较各亚组的骨量分布. 用线性回归分析 PSQI评分 与BMD的关系, 用受试者工作特征曲线评价PSQI评分对SCH患者发生骨质疏松症的预测价值. 结果　非SD组和 SD组吸烟史, PSQI评分, Ⅰ型胶原羧基端肽β特殊序列, LS BMD, FN BMD, WB BMD, LS T值, FN T值, WB T值比较 差异有统计学意义 (P均<0. 05) . 各亚组骨量分布比较差异有统计学意义 (P<0. 05) . PSQI评分分层回归分析结果 显示, 在睡眠重度障碍组, SD负向影响LS BMD, WB BMD (P均<0. 05), 而对FN BMD无影响 (P均>0. 05), 睡眠重度 障碍是 BMD的独立影响因素. PSQI评分预测 SCH 合并 SD 患者发生骨质疏松症的曲线下面积为 0. 824 (95% CI： 0. 758~0. 889), 最佳截断值为 12. 5分, 此时其预测灵敏度为 84. 3%, 特异度为 65. 7%. 结论　合并SD的SCH患者 BMD降低, 睡眠重度障碍是BMD降低的危险因素, PSQI评分对SCH患者骨质疏松症的发生有一定预测价值. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship between circadian sleep-wake biorhythm and prognosis in patients with middle cerebral artery acute ischemic stroke. Methods A total of 71 patients with acute ischemic stroke of middle cerebral artery were selected as the case group，and 67 patients without acute ischemic stroke and cerebrovascular stenosis were selected as the control group. According to the modified Rankin score at discharge, patients with acute ischemic stroke were subdivided into the good prognosis group (53 cases) and the poor prognosis group (18 cases). General clinical data of patients were collected, and differences of circadian rhythm, daytime sleep-wake rhythm, nighttime sleep wake rhythm and circadian sleep-wake rhythm indexes were analyzed and compared between the two groups. Multivariate Logistic stepwise regression analysis was used to analyze prognostic factors of acute ischemic stroke in middle cerebral artery. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of relevant variables. Results Age, male ratio, hypertension, diabetes, hyperlipidemia, smoking and drinking history were significantly higher in the case group than those in the control group. Daytime stability (IS) in the case group was lower than that in the control group (P＜0.05). Daytime total sleep time, wake time after falling asleep, light sleep period, deep sleep period, non-rapid eye movement (NREM) sleep period, rapid eye movement (REM) sleep period and the proportion of deep sleep period, the proportion of REM sleep period were higher in the case group than those of the control group, while the REM sleep latency and the proportion of light sleep period were lower than those of the control group (P＜0.05). The total sleep time, wake time, light sleep period, NREM sleep period and REM sleep period were higher in the case group than those of control group, while the proportion of sleep latency and REM sleep period were lower than those of the control group (P＜0.05). The proportion of increased circadian sleep, increased daytime sleep and low sleep efficiency at night were higher in the case group than those of the control group (P＜0.05). Logistic stepwise regression analysis showed that daytime REM sleep was a prognistic factor in middle cerebral artery acute ischemic stroke. During daytime REM sleep, the area under ROC curve (AUC) was 0.705, the sensitivity was 0.811 and the specificity was 0.611. Conclusion After acute ischemic stroke of middle cerebral artery, the circadian sleep-wake rhythm is unbalanced, which is manifested as poor daytime stability, increased daytime sleep, increased circadian sleep and low sleep efficiency at night. Daytime REM sleep has predictive value for prognosis of acute ischemic stroke of middle cerebral artery. [ABSTRACT FROM AUTHOR]

The patients undergoing the treatment of assisted reproductive technology, as a special group that is different from other groups of diseases, are prone to sleep disorders due to the impact of physiological and psychosocial factors. In this review, the current status, assessment tools, and non-pharmacological intervention of sleep disorders in patients undergoing assisted reproductive technology were introduced. The appropriate tools were used to evaluate the degree of sleep disorders effectively. The appropriate intervention measures can improve the sleep quality of patients, including digital cognitive behavioral therapy, mindfulness-based stress reduction, music therapy, aerobic and resistance exercises and progressive muscle relaxation. This review will provide a reference for the evaluation of sleep disorders and non-pharmacological intervention for those patients undergoing assisted reproductive technology for pregnancy. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Prevention & Treatment For Stomatological Diseases is the property of Journal of Prevention & Treatment For Stomatological Diseases Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the occupational health literacy level among workers in two key industries in Qingpu District of Shanghai and to identify influencing factors in order to provide references for formulating relevant occupational health measures. Methods From June to September 2022, a multi -stage cluster random sampling method was used to select 965 workers from 18 enterprises in the automobile manufacturing and electrical machinery and equipment manufacturing industries in Qingpu District. The National Key Population Occupational Health Literacy Monitoring Survey Individual Questionnaire was distributed to collect data on basic information, occupational health literacy levels, and physical and mental health status. The factors affecting workers' occupational health literacy levels were analyzed. Results The overall occupational health literacy level among these surveyed workers was 66.2%, with the levels for the four dimensions as: basic knowledge of occupational health protection (87.8%), healthy work methods and behaviors (77.8%), knowledge of occupational health laws (73.4%), and basic skills of occupational health protection (42.8%). Among the four types of physical and mental health problems, the detection rates were 64.1% for depression, 34.0% for sleep disorders, 22.3% for anxiety, and 20.9% for occupational stress. Multivariate linear regression analysis showed that compared to workers with primary school education or below, those with junior high school education had a 6.0% higher score of occupational health literacy, and the occupational health literacy score rate of workers with high school, vocational high school, technical secondary school, college, bachelor degree, and above increased by about 8% (P < 0.05). Compared to workers in small enterprises, workers in medium-sized enterprises had a 2.9% lower score of occupational health literacy (P < 0.05). The detection rates of depression, sleep disorders, and occupational stress were negatively correlated with occupational health literacy level (r = -0.115, -0.093, -0.157, P < 0.01). Conclusions The overall level of occupational health literacy among workers in these two key industries was not high, the basic skills of occupational health protection were lacking, and the incidence of depression was relatively high. The targeted intervention measures should be developed for the corresponding enterprises and populations to improve their workers' occupational health literacy levels. [ABSTRACT FROM AUTHOR]

Objective To screen, extract and summarize the best evidence related to non -drug prevention and management of sleep disorders in breast cancer survivors, providing a relevant practical basis for sleep management in breast cancer survivors. Methods The PIPOST model was used to construct evidence-based questions. According to the "6S" model of evidence-based search resources, computer-aided literature search was conducted on PubMed, BMJ Best Practice, JBI Evidence-Based Health Care Center, NICE, Web of Science, American Society of Clinical Oncology (ASCO), CNKI, and Wanfang Database. The search content included clinical guidelines, expert consensus, systematic evaluation, randomized controlled trials, clinical decision -making, and evidence summary. Results A total of 13 references were included, including 2 clinical guidelines, 2 expert consensus, 3 systematic reviews, and 6 randomized controlled trials; 27 pieces of evidence were summarized with 6 dimensions, i.e., sleep disorder screening and evaluation, sports activity recommendations, mindfulness training treatment, cognitive behavioral intervention, traditional Chinese medicine treatment, and sleep hygiene and health education. Conclusions The 27 best evidences summarized in this study provides a relevant practical basis forsleep management of breast cancer survivors, anditis helpfulto combinethe evidence with clinical practicein developing systematic, comprehensive and individualized sleep management programs. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To summarize the nursing of a patient with malignant peritoneal mesothelioma. The key points of nursing include: pain control and nursing, nutrition risk screening and nutrition support, nursing and management of falls and insomnia, maintenance of infusion port, and psychological care. Targeted nursing interventions are effective to relive the pain and other symptoms and improve the patient adherence to the treatment (本文总结1例恶性腹膜间皮瘤患者的护理经验。护理要点包括: 疼痛的护理和处理, 营养风险筛查及营养支持, 跌倒、失眠的护理, 输液港的维护, 心理护理。通过开展针对性治疗和护理, 有助于缓解患者不适症状, 提高治疗依从性。)

Objective To investigate the effect of narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing in the treatment of post-stroke sleep disorder. Methods From June 2022 to December 2022, 80 patients with sleep disorder after stroke admitted to the Rehabilitation Department of Beijing Longfu Hospital were selected and randomly divided into a control group and a study group, with 40 patients in each group. Patients in the control group received routine nursing intervention, and those in the study group were given narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing in addition to the routine nursing. Pittsburgh Sleep Quality Index(PSQI) scale was used to measure patient’s sleep quality. Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) were performed to evaluate the patient’s anxiety and depression level. Results The PSQI score was decreased in both two groups after intervention, and PSQI score in the study group was lower than that in the control group (P＜0. 01). The HAMA and HAMD scores were decreased in both two groups after intervention, and HAMA and HAMD scores in the study group were lower than that in the control group (P＜0. 01). Conclusion The narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing can effectively improve the sleep quality of stroke patients with sleep disorder. (目的 探讨叙事护理联合中药泡足和耳穴贴压治疗脑卒中后睡眠障碍的效果。方法 2022年6月—12月, 选取北京市隆福医院康复科收治的脑卒中后睡眠障碍患者80例, 采用随机数字表法分为对照组和研究组, 各40例。对照组患者将接受常规护理干预, 研究组在对照组的基础上接受叙事护理联合中药泡足和耳穴贴压治疗, 采用匹兹堡睡眠质量指数(PSQI)评价患者睡眠质量, 采用汉密尔顿焦虑量表(HAMA)评分和汉密尔顿抑郁量表(HAMD)评分评估患者焦虑和抑郁程度。结果 干预后, 两组PSQI量表总分较干预前下降, 且研究组PSQI量表总分低于对照组, 差异有统计学意义(P＜0. 01)。干预后, 两组HAMA和HAMD量表总分较干预前下降, 且研究组HAMA和HAMD量表总分低于对照组, 差异有统计学意义(P＜0. 01)。结论 叙事护理联合中药泡足和耳穴贴压能有效改善脑卒中后睡眠障碍患者的睡眠质量和负性情绪。)

Adverse drug reactions have a direct impact on the treatment effect and quality of life of patients with malignant tumors. Research has found that moxibustion can effectively relieve the chemotherapy-induced adverse drug reactions. This article summarized the interventional mechanism of moxibustion and its clinical application for relieving chemotherapy-induced adverse drug reactions, in order to guide the clinical practice and improve the quality of life of cancer patients with chemotherapy. (肿瘤化疗相关不良反应严重影响患者的治疗和生活质量。艾灸可以缓解恶性肿瘤化疗相关不良反应, 减轻患者临床症状。本研究就艾灸疗法干预机制及其用于缓解肿瘤患者化疗相关不良反应的研究现状进行综述, 以期更好地指导临床实践, 提高化疗患者的生活质量。)

目的　分析安徽省中老年人群认知障碍(CI)发病的影响因素, 建立并验证 CI风险预测模型。方法　采 取多阶段分层整群抽样方在安徽省抽取 3 200例中老年人(45岁以上)进行问卷调查, 采用中文版简易精神状态检 查量表(MMSE)对认知功能进行评估。采用 R4. 2. 2 软件将研究对象随机分为建模组和验证组(样本量比例为 7∶3), 计算安徽省中老年人群 CI的患病率, 分析安徽省中老年人群发生 CI的独立危险因素, 应用 R软件建立预测 CI的列线图并验证预测效能。结果　共纳入有效问卷数目共计3 059份(应答率95. 6%), 其中确诊CI 384例, 患病 率为 12. 6%, 其中 2 141 例(CI 265 例, 非 CI 1 876 例)纳入建模组, 918 例(CI 119 例, 非 CI 799 例)纳入验证组。 多因素 Logistic分析结果显示, 女性, 高龄, 家族史, 低文化程度, 吸烟, 睡眠障碍, 高血压, 脑卒中, 糖尿病为CI的独 立危险因素, 而运动为其独立保护因素；根据以上影响因素绘制列线图预测模型并验证, 建模组和验证组受试者工 作特征曲线下面积分别为0. 845(95% CI 0. 822 ~ 0. 868)和0. 868(95% CI 0. 835 ~ 0. 902), 提示该模型预测效能良 好。霍斯默·莱梅肖拟合优度检验结果显示, 建模组和验证组P值分别为0. 325和0. 722, 提示该模型具有较好的拟 合优度；决策曲线评估列线图在阈值内具有较高的获益性。结论　女性, 高龄, 家族史, 低文化程度, 吸烟, 睡眠障 碍, 高血压, 脑卒中, 糖尿病为安徽省中老年人群发生CI的独立危险因素, 而运动为其独立保护因素；根据上述影响 因素建立的CI风险预测模型预测效能较好。 [ABSTRACT FROM AUTHOR]

压力系统是机体在压力源刺激下做出的一系列跨系统复杂性综合反应, 参与调节睡眠-觉醒周期、维持 正常生物钟及昼夜节律。2019 冠状病毒病 (COVID-19) 作为慢性压力性生活事件, 长期过度激活压力系统, 造成睡 眠结构的改变, 并以慢性压力、强压力源的形式影响记忆过程, 长期应激下压力记忆与恐惧记忆得到加强巩固, 加之 心理因素对睡眠压力的附加, 导致长期睡眠障碍。同时, 有别于其他压力, 严重急性呼吸综合征 (SARS) 相关冠状病 毒感染包括严重急性呼吸综合征冠状病毒2 (SARS-CoV-2) 可能是由于其可造成下丘脑-垂体-肾上腺 (HPA) 轴长期 无法恢复、大脑区域的直接靶向性损伤等因素, 使得压力系统产生特殊的长期效应, 从而参与了 “长新冠”-睡眠障 碍的发生。 [ABSTRACT FROM AUTHOR]

Objective: To evaluate the effect of applying behavioral analysis（ABA) combined with sensory integration training on behavior, development and sleep disorders in children with autism spectrum disorder（ASD). Methods: 62 children with ASD admitted to our hospital from January 2021 to January 2023 were randomly divided into a Matched group and an observation group, with 31 cases in each group. Both groups received ABA therapy, and the observation group received sensory integration training on this basis. Evaluate and compare the behavior, development and sleep status of the two groups. Results: The total effective rate of the observation group was87.10%, higher than 61.29% in the matched group（P＜0.05). After the treatment, the item scores and total scores on ABC and ATEC in both groups decreased compared to before the treatment, while the observation group showed a greater decrease, with a significant difference compared to the matched group（P＜0.05). Compared with pretherapy, the Gesell scale scores of the two groups increased post-treatment（P＜0.05), while the observation group showed a increase compared to the matched group（P＜0.05). There was no difference in the item score and total score of CSHQ between the two groups pretherapy（P＞0.05), but post-treatment, all CSHQ scores and total scores were lower in the observation group compared with the matched group（P＜0.05). Conclusion: ABA therapy combined with sensory integration training can alleviate the symptoms of ASD in children, improve behavioral status and sleep quality, promote their development, and improve clinical efficacy. [ABSTRACT FROM AUTHOR]

Perimenopausal period is a special period in the life process of the female. During this period, the reproductive function of women declines and the levels of hormones fluctuate, leading to a series of clinical symptoms. Sleep disorder is one of the common symptoms. The factors and pathogenesis of perimenopausal sleep disorders are mainly related to hormonal changes, vasomotor symptoms and neurotransmitter unbalance. It is also related to anxiety and depression, emotional disorder, sleep-wake cycle, down-regulation of melatonin, apnea and hypopnea, restless leg syndrome, etc. Aging itself and metabolic problems also play a role. In this article, we discuss the related factors and pathogenesis of perimenopausal sleep disorders from the different perspectives. [ABSTRACT FROM AUTHOR]

Sarcopenia is a disease mainly characterized by a decrease in skeletal muscle mass and muscle strength in the elderly population and chronic disease patients. Its main pathogenic factors include endocrine metabolic disorders, insufficient physical activity, chronic inflammation, etc. Recently, the impact of sleep disorders on sarcopenia has begun to receive attention, more studies have shown a correlation between sleep disorders and sarcopenia. Sleep disorders can lead to circadian disorders and thus affect the secretion of hormones such as insulin and sex hormones, as well as promote the secretion of pro-inflammatory inflammatory factors, all of which can lead to abnormal synthesis and breakdown of skeletal muscle proteins and may cause the development of sarcopenia. Therefore, exploring the relationship between the two and targeting sleep disorders may be effective in the prevention and treatment of sarcopenia and is a potential treatment strategy to intervene in the development of sarcopenia. [ABSTRACT FROM AUTHOR]

Objective To investigate the anxiety， depression and sleep disorders in patients with early dysfunctional filtration blebs who underwent needle revision of filtration bleb after glaucoma trabeculectomy. Methods We selected 30 patients who recovered to normal 6 months after glaucoma trabeculectomy(Group A), 30 patients with early dysfunc‐ tional filtration blebs who underwent needle revision of filtration bleb after glaucoma trabeculectomy(Group B), and 30 healthy adults(Group C) . Anxiety， depression and sleep disorders were scored using Self-Rating Anxiety Scale(SAS), Self-Rating Depression Scale(SDS) and Pittsburgh Sleep Quality Index(PSQI) . We compared SAS， SDS， PSQI scores and the positive rate of anxiety， depression and sleep disorders among the three groups. The correlation of SAS， SADS and PSQI scores in patients with early dysfunctional filtration blebs was analyzed by Spearman correlation analysis. Results There were no significant differences in gender， age， educational level or marital status among the three groups(all P> 0. 05), and the balance between the groups was comparable. Significant differences were found in SAS， SDS and PSQI scores between the three groups(all P<0. 05) . There were significant differences in SAS， SDS and PSQI scores between the groups B and C(all P<0. 05) . Significant difference was found in PSQI score between group A and group C(P< 0. 05) . SAS score of 45， SDS score of 50， and PSQI score of> 7 were used as the positive determination criteria for anxi‐ ety， depression， and sleep disorders， respectively. There were significant differences in the positive rates of depression and sleep disorders among these three groups(all P<0. 05) . Significant differences were found in the positive rates for anx‐ iety， depression and sleep disorders between the group B and group C(all P<0. 05) . There was significant difference in the positive rate of sleep disorder between groups B and A， and between groups A and C(all P<0. 05) . PSQI score was positively correlated with SAS score(r=0. 511) and SDS score(r=0. 296) in patients of group B(P<0. 05), and SAS score was positively correlated with SDS score(r=0. 355，P<0. 05) . Conclusion Patients with early dysfunctional filtration blebs who underwent needle revision of filtration bleb after glaucoma trabeculectomy have high incidences of anxiety， depression and sleep disturbance within 6 months， so necessary psychological intervention should be given. [ABSTRACT FROM AUTHOR]

Objective To explore the relationship between sleep disorder, depression, and health-related quality of life in the elderly, and the mediating effect of depression on sleep disorder and health-related quality of life. Methods In total 3 612 elderly people over 60 years old in Hebei Province were selected by stratified random sampling, and the related data were collected with the use of Pittsburgh sleep quality index (PSQI), the simplified geriatric depression scale (GDS-15), and concise health quality of life scale (SF-36). Results There was a positive correlation between sleep disorder and depression in the elderly (r = 0.39, P < 0.001), and a negative correlation between sleep disorder, depression, and health-related quality of life (r = 一0.43 and -0.40, P < 0,001). Sleep disorders and depression in the elderly had negative predictive effects on health-related quality of life (B =-0.26, -0.194, -0.43, and 一0.520), and depression played a mediating role between sleep disorders and physical health-related quality of life in the elderly, accounting for 39.29% of the total effect. Depression played a mediating role between sleep disorders and mental health -related quality of life in the elderly, and the intermediary effect accounted for 51.57% of the total effect. Conclusion The health-related quality of life of the elderly with sleep disorder and depression is poor. Sleep disorder of the elderly not only directly affects tlie healtli-related quality of life, but also indirectly at fects the physical and mental health-related quality of life of the elderly through depression. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Sichuan University (Medical Science Edition) is the property of Editorial Board of Journal of Sichuan University (Medical Sciences) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To analyze the research hotspot and trend of Traditional Chinese Medicine (TCM) nursing of post-stroke sleep disorders based on CiteSpace, and provide reference for clinical nursing and scientific research. Methods The literature on TCM nursing of sleep disorders after stroke published by CNKI, Wanfang, VIP and CBM databases from January 31, 2023 was retrieved. The annual number of publications, authors, research institutions, keyword co-occurrence, keyword clustering and keyword timeline were analyzed by CiteSpace software. Results A total of 177 literatures met the requirements were retrieved, and the overall number of publications was on the rise. The cooperation network between the authors and research institutions was not yet mature. The bibliometric results showed that research hotspots of literatures wereextended care, emotion care and TCM nursing technology. Conclusion TCM nursing intervention for sleep disorders after stroke has achieved good results, which can significantly improve the sleep quality of patients, promote the outcome of the disease, and improve the quality of life of patients. (目的 使用CiteSpace工具对卒中后睡眠障碍进行分析, 为今后的临床护理和相关研究提供一定的帮助和参考。方法 检索关于卒中后睡眠障碍中医护理研究的文献, 主要检索的关键词包括脑卒中、卒中后睡眠障碍、睡眠障碍、中医护理、中医护理技术等, 检索数据库选择中国知网(CNKI)、万方(Wanfang Data)、维普(VIP)以及中国生物医学文献数据库(CBM), 时间截止到2023年1月31日, 使用CiteSpace软件进行分析, 主要包括年发文量、作者、研究机构、关键词共现、聚类、时间线等。结果 通过检索, 共计有177篇文献符合本次研究需求; 经过分析发现, 相关文献资料呈上升趋势, 逐年增加; 在研究中能看到相关的研究者和研究机构之间尚未形成成熟的合作关系网络; 同时, 卒中后睡眠障碍在中医研究中, 主要的研究焦点在于延续护理、情志护理以及中医护理技术等。结论 通过对相关文献的分析和整理发现, 针对卒中后睡眠障碍, 中医护理干预能够显著改善患者睡眠质量, 促进患者病情的改善和生活质量的提升, 在临床使用中有着非常理想的效果。)

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Objective To analyze the influencing factors of sleep disorders and the relationship between working hours per week and sleep disorders among employees in oil field enterprises in Gansu Province. Methods The employees of oil field enterprises in Gansu Province were investigated from January to June 2022. The basic information and sleep quality data of 2 178 subjects were collected by self-made questionnaire combined with Pittsburgh Sleep Quality Index scale. The normal sleep group and sleep disorder group were matched according to 1:1 by propensity score matching (PSM). Univariate analysis and multivariate logistic regression analysis were performed to analyze the influencing factors of sleep disorder. Restricted cubic spline (RCS) model was used to analyze the dose-response relationship between working hours per week and sleep disorder. Results The detection rate of sleep disorders among oil field workers in Gansu Province was 45.68%. In total 957 pairs of propensity scores were matched successfully, and the baseline data of the two groups were basically balanced after matching. Multivariate logistic regression analysis showed that hypertension (OR=1.507, 95%CI: 1.124-2.022), diabetes mellitus (OR=1.743, 95%CI: 1.020-2.980), length of service of 10 to 19 years (OR=1.325, 95%CI: 1.021-1.719), length of service of 20 to 29 years (OR=1.437, 95%CI: 1.071-1.927), length of service ≥ 30 years (OR=1.581, 95%CI: 1.095-2.282), weekly working hours of 49 to 55 hours (OR=1.381, 95%CI:1.026-1.859), working hours ≥ 56 hours per week (OR=1.999, 95%CI: 1.551-2.575), and work injury (OR=1.479, 95%CI: 1.114-1.962) were the risk factors of sleep disorder, while physical exercise (OR=0.694, 95%CI: 0.573-0.839) was the protective factor. The results of restricted cubic spline model showed that there was a non-linear dose-response relationship between the working hours per week and sleep disorders. When the working hour per week exceeded 40 hours, the risk of sleep disorders increased. Conclusion The sleep problem of oil field workers should be paid attention to. Enterprises should urge workers to develop healthy living habits, improve working environment, arrange working hours reasonably, and improve sleep quality, to reduce the risk of sleep disorders. [ABSTRACT FROM AUTHOR]

Objective: To observe intervention effect of Gubenjiannaoye on sleep disorders, and to preliminary analyze its mechanism. Methods: Thirty male SPF-grade 6-month-old APP/PS1 double transgenic mice and 10 male SPF-grade 6-month-old normal mice were selected. APP/PS1 mice were randomly assigned to model group and experimental groups(Gubenjiannaoye low-dose and high-dose groups), mice in experimental groups were given Gubenjiannaoye by gavage, control group and model group were gavaged with same amount of normal saline. Behavioral level, circadian rhythm, serum TNF-α, IL-1β levels, hippocampal Aβ1-42, cell apoptosis levels were detected, and HE and Nissl staining were detected to observe histopathological characteristics of hippocampus. Results: Compared with normal mice, escape latency time, light activity time, dark activity time and total activity time, serum TNF-α, IL-1β levels, hippocampal Aβ1-42 level, cell apoptosis rate of mice were increased significantly in model group(P<0.05), and arrangement of nerve cells in hippocampus was disordered, cell volume and number were decreased, and intracellular Nissl bodies were decreased; compared with model mice, after Gubenjiannaoye intragastric administration, sleep disturbance, learning and memory ability, inflammatory response, neuronal apoptosis level in hippocampus and pathological conditions of mice were significantly improved. Conclusion: Gubenjiannaoye has a certain protective effect on nerve function of APP/PS1 mice with sleep disorders, whose mechanism may be related to inhibition of Aβ deposition in AD brain tissues and further inhibition of inflammation and nerve cell apoptosis in brain tissues. [ABSTRACT FROM AUTHOR]

Objective To systematically evaluate the prevalence of sleep disorders in Chinese women aged 40 to 65 years. Methods A computer search in CBM, CNKI, Wan Fang, VIP, PubMed, Embase, and Web of Science databases was conducted for cross-sectional studies related to sleep disorders in Chinese women aged 40 to 65 years old. Stata 17,0 software was used for m eta-analysis. Results A total of 31 studies were included, involving 36 564 women. The results of meta-analysis showed that the prevalence rate of sleep disorders in Chinese women aged 40 to 65 was 39.1% (95%CIi 32,l%-46.2%). The results of subgroup analysis showed that the prevalence rate of sleep disorders increased with the increase of age and the occurrence and development of menopausal process. The prevalence rate of patients with sample size < 2 000 was higher than that of those with sample size 3 2 000, Conclusion The current evidence shows that the prevalence rate of sleep disorders in Chinese women aged 40 to 65 is 39.1%, and the prevalence rate is higher in women 3 55 years old and postmenopausal women. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the clinical efficacy of Zhichan decoction combined with repeated transcranial magnetic stimulation (rTMS) in the treatment of Parkinson’s disease (PD) and its impact on sleep and depression in patients. Methods: 80 PD patients admitted to our hospital from September 2022 to January 2023 were randomly divided into a control group and an observation group,with 40 patients in each group. The control group was treated with conventional Western medicine and r TMS, while the observation group was supplemented with traditional Chinese medicine Zhichan decoction. Evaluate and compare the clinical efficacy, sleep and depression status between the two groups. Results: After treatment, the traditional Chinese medicine syndrome scores of the two groups decreased compared to before treatment (P＜0.05), while the observation group showed a higher decrease than the control group (P＜0.05) .There was no difference in total effective rate between the two groups (P＞0.05), but the observation group had a higher marked improvement rate than the control group (P＜0.05) . Compared with before treatment, the scores of UPDRS-I, UPDRS-II, UPDRS-III, NMSE and HAMD scales were increased, while the PDSS scores were increased (P＜0.05) in the two groups after treatment. However, the observation group showed a greater increase/decrease (P＜0.05) . There was no difference in the incidence of adverse reactions between the two groups (P＞0.05) . Conclusion: The combination of Zhichan decoction and r TMS has a definite therapeutic effect on PD, which can effectively improve clinical symptoms, improve sleep quality, alleviate depression, and has good safety. [ABSTRACT FROM AUTHOR]

Objective To explore the clinical characteristics and influencing factors of fatigue symptoms in patients with interstitial lung disease (ILD). Methods A total of 238 patients with ILD were selected. Gender, age, marital status, body mass index (BMI), occupation, education, smoking and alcohol consumption of patients were collected. The pulmonary function of patients was measured. The percentage of forced vital capacity in the predicted value (FVC% pred), the percentage of forced expiratory volume in the first second in the predicted value (FEV1%pred), the percentage of forced expiratory volume in the end of the first second in the predicted value (FEV1/FVCpred) and the percentage of diffusing capacity of the lungs for carbon monoxide in the predicted value (DLCO%pred) were detected. The fatigue rating scale (FAS) was used to evaluate the physical and mental fatigue of patients. The improved Medical Research Council Respiratory Questionnaire (mMRC) was used to assess the degree of dyspnea. Charlson comorbidity index was used to evaluate the severity of comorbidity. The hospital anxiety and depression scale (HADS) including HADS-A and HADS-D were used to score the anxiety and depression of patients. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality of patients. The differences of FAS scores and the correlation between FAS scores and clinical features were analyzed. Multiple linear stepwise regression analysis was used to explore the influencing factors of fatigue in ILD patients. Results The FAS score of 238 patients was (26.03 ± 9.53), of which 159 (66.81%) experienced fatigue and 60 (37.74%) experienced severe fatigue. The FAS scores of mMRC grade 0 and 1 ILD patients were lower than those of mMRC grade 2, 3 and 4 patients, and the FAS scores of mMRC grade 2 ILD patients were lower than those of mMRC grade 4 patients (P＜ 0.01). There were no significant differences in FAS scores between patients with different course of disease, age, sex, marriage, work, education level, smoking, drinking, ILD type and Charlson complication index. FAS score was positively correlated with age, disease course, HADS-A, HADS-D and PSQI, and negatively correlated with DLCO% pred (P＜0.05). Multiple linear stepwise regression analysis showed that HADS-D, mMRC, PSQI and disease course were influencing factors of FAS score (P＜0.05). Conclusion The incidence of fatigue is high in ILD patients, and the long course of disease, dyspnea, depression and sleep disorders are important influencing factors of fatigue. [ABSTRACT FROM AUTHOR]

Objective: To explore the risk factors of sleep disorders in elderly patients with Parkinson's disease (PD), and to observe the effects of sleep disorders on cognitive function, mental status and frailty. Methods: 91 elderly patients with PD who were admitted to Chinese People's Liberation Army Navy Qingdao Special Service Healing Center from March 2018 to September 2021 were selected as research objects. According to whether they had sleep disorders, 91 patients were divided into sleep disorder group(n=56) and non-sleep disorder group (n=35). The Montreal Cognitive Assessment Scale (MoCA) was used to assess the cognitive function status of all patients. Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) were used to evaluate the anxiety and depression condition of the patients. The Tilburg frailty Assessment Scale was used to assess frailty condition of all patients. Multivariate Logistic regression analysis was used to explore the risk factors of sleep disorders in elderly patients with PD, and the effects of sleep disorders on cognitive function, mental status and frailty were observed. Results: The visual space and executive function, language, naming, delayed recall, attention, abstraction, orientation score and total score in the sleep disorder group were all lower than those in the non-sleep disorder group(P<0.05). The HAMA and HAMD scores in the sleep disorder group were higher than those in the non-sleep disorder group (P<0.05). The mental frailty, physical frailty, social frailty score and total score in the sleep disorder group were higher than those in the non-sleep disorder group (P<0.05). The results of multivariate Losgistic regression analysis showed that higher HAMA score, higher equivalent dose of doxiazid tablets, higher HAMD score and higher Hcy were risk factors for sleep disorders in elderly patients with PD (P<0.05). Conclusion: The higher HAMA score, higher Hcy score, higher equivalent dose of doxiazid tablets and higher HAMD score are risk factors for sleep disorders in elderly patients with PD. At the same time, sleep disorders can aggravate cognitive dysfunction and degree of frailty in elderly patients with PD, and increase depression and anxiety. [ABSTRACT FROM AUTHOR]

Objective To investigate the depressive symptoms and risk factors among frontline workers in the secondary industry in Tongling City in order to provide a basis for the prevention of psychological problems among occupational populations in Tongling City. Methods By convenience sampling method, 389 frontline workers from 9 enterprises in the secondary industry, namely non -metal mining and dressing industry, rubber and plastic products industry, metal mineral products industry, and textile and garment enterprises, in Tongling City from July to September 2022 were anonymously surveyed with the Monitoring and Intervention Questionnaire for Occupational Health Literacy of Key Populations developed by the Chinese Center for Disease Control and Prevention. Multivariable logistic regression models were used to analyze the risk factors for depressive symptoms among these workers. Results The prevalence of depressive symptoms among 389 frontline workers in the secondary industry was 14.40%, while 123 individuals (31.62% ) had sleep disturbances. Multivariable logistic regression analysis showed that for every 1-year increase in the age of workers, the risk of abnormal depressive symptoms increased by 1.04 times (95%CI: 1.01-1.07); compared with workers with weekly working hours ≤ 40 h, those with weekly working hours > 48 h had an increased risk of abnormal depressive symptoms by 4.29 times (95% CI: 1.44 -12.78); compared with workers without anxiety, those with anxiety had an increased risk of abnormal depressive symptoms by 10.49 times (95% CI: 5.52 -19.94). Marital status, education level, monthly income, enterprise character, industry type, and the presence or absence of sleep disturbances were not risk factors for depressive symptoms among these workers. Conclusions Frontline workers with longer weekly working hours, specifically in labor -intensive enterprises with assembly line operations, were prone to having depressive symptoms. The enterprises should pay attention to older employees and those with longer working hours, improve organizational management systems, arrange working hours scientifically and rationally, and reduce the occurrence of anxiety and depressive symptoms among employees. [ABSTRACT FROM AUTHOR]

Objective To evaluate the effect of auricular acupoint buried beans combined with Nazi method of midnight-noon ebb-flow on relieving sleep disorders in night shift nurses. Methods Eighty-four nurses with sleep disorders were randomly divided into the observation group and a control group, with 42 cases in each group. The control group received the conventional treatment of auricular acupoint buried beans, and the observation group was given the combination treatment of auricular acupoint buried beans combined with Nazi method of midnight-noon ebb-flow. Pittsburgh Sleep Quality Index (PSQI) and the Quality of Life Scale (SF-36) were used to evaluate the sleep quality and quality of life of nightshift nurses before and after the intervention. Results The scores of each dimension of PSQI in the observation group were lower than those in the control group after intervention(P＜0. 05). The SF-36 score decreased in both groups after intervention, and scores of each dimension except of physical function in the observation group were higher than those in the control group after intervention(P＜0. 05). Conclusion Both intervention methods can improve the sleep quality and quality of life of nightshift nurses, and auricular acupoint buried beans combined with Nazi method of midnight-noon ebb-flow was associated with a better treatment effect of relieving sleep disorders compared with conventional auricular acupoint buried beans. (目的 评价耳穴埋豆联合子午流注纳子法对夜班护士睡眠障碍改善的效果。方法 将84例睡眠障碍的护士随机分为观察组和对照组, 每组42例。对照组实施常规耳穴埋豆, 研究组实施耳穴埋豆联合子午流注纳子法。采用匹兹堡睡眠质量指数量表(PSQI)和生活质量量表(SF-36)评价夜班护士的睡眠质量和生活质量。结果 干预后, 观察组夜班护士PSQI量表各维度评分均低于对照组, 差异有统计学意义(P＜0. 05)。干预后, 两组SF-36量表各维度得分均较干预前升高, 且观察组SF-36量表中生活职能、躯体疼痛、一般健康状况、精力、社会职能、情感职能和精神健康维度得分高于对照组, 差异有统计学意义(P＜0. 05)。结论 两种干预方法均可提高夜班护士睡眠质量和生活质量, 耳穴埋豆联合子午流注纳子法联合对夜班护士睡眠质量的改善效果较常规耳穴埋豆更佳。)

卒中后失眠是在卒中后首次出现并达到失眠诊断标准的一组临床综合征，与临床常见失眠相类似，主要表现为睡眠深度异常和平均每晚睡眠时间少于6 h。meta分析显示，卒中急性期、亚急性期及恢复期患者符合失眠障碍诊断标准的比例分别为32.5%、34.8%和37.1%。卒中后失眠不仅增加了卒中死亡及复发风险，而且对卒中康复与预后造成不利影响。本文对卒中后失眠的发病情况、发病机制及治疗等进行综述，以便为临床实践提供信息，并为卒中后失眠提供针对性干预治疗措施。 Abstract: Post stroke insomnia (PSI) is a group of clinical syndromes that first appear after a stroke and meet the diagnostic criteria for insomnia. Similar to common clinical insomnia, the main manifestations are abnormal sleep depth and average sleep time less than 6 hours per night. Meta-analysis showed that 32.5%, 34.8% and 37.1% of patients in acute, subacute and convalescent stages of stroke met the diagnostic criteria for insomnia disorders, respectively. PSI not only increases the risk of stroke death and recurrence, but also has adverse effects on stroke rehabilitation and prognosis. This paper reviews the incidence, pathogenesis, and treatment of insomnia after stroke, in order to provide information for clinical practice and provide targeted intervention and treatment measures for insomnia after stroke.

卒中相关睡眠障碍（stroke-related sleep disorders，SSD）是卒中后常见症状，且易被忽视。2019年，北京神经内科学会联合相关专业学会及相关领域专家制定并发表了《卒中相关睡眠障碍评估与管理中国专家共识》。北京神经内科学会汇集各方意见和建议，结合最新临床研究成果，完成了“共识”2023年更新版。2023版“共识”主要聚焦有循证医学证据的SSD评估及治疗方法的新进展，并增加了一些循证证据较少的睡眠障碍亚型治疗方面的专家推荐意见，增加其临床实用性及可操作性，有效指导临床医师规范诊疗SSD。

Physical therapy is an important means to improve people's sleep quality. The technical methods of improving sleep including therapies of light, sound, vibration, electromagnetic field, temperature, pressure / gravity stimulation were reviewed. Effects and mechanisms of physical factors to improve sleep and the research progress of sleep intervention at home and abroad were introduced, including the related physical therapy instruments. This review is expected to provide theoretical basis for formulating scientific and reasonable physical treatment plan for sleep disorders. [ABSTRACT FROM AUTHOR]