Search

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Obstetrics & Gynecology is the property of TianJin Medical Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Obstetrics & Gynecology is the property of TianJin Medical Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To evaluate the literature on off-label drug use of levocarnitine injection by the Jadad scale, so as to assess the medication rationality of levocarnitine injection in Ruijin Hospital Affiliated to School of Medicine, Shanghai Jiaotong University. Methods: All the literature on off-label drug use of levocarnitine injection were included and evaluated by the modified Jadad Scale, Literature with scores of more than 4 were selected as evidence for off-label drug use. Totally 360 prescriptions using levocarnitine injection were randomly selected to analyze the medication rationality of levocarnitine injection in this hospital. Results: Levocarnitine injection was usually used for nutrition myocardium, stablization of cardiac function, improvement of myocardial metabolism and so on in the literature selected by Jadad scale. Prescription reviews revealed that there were 309 cases of supernumerary indication drug use, accounting for 85.83%. Levocarnitine injection was mainly used as adjuvant drugs after cardiac surgery and resection of thoracic tumor, and no adverse drug reactions were reported. Conclusion: It would be a new tool that modified Jadad scale could be used for assessment of medication rationality by screening high quality literature. [ABSTRACT FROM AUTHOR]