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The present situation of safety management of chemical laboratory in universities is reviewed and should be improved. The development trend of teaching and scientific research decided the laboratory safety management level. The problems existing in our chemistry laboratory are analyzed thoroughly and the necessity of carrying out knowledge competition on chemistry laboratory safety is put forward. It is suggested there should be enough support and guarantee system corresponding to laboratory safety knowledge competition. The competition subjects are defined and the organizational form and contest content are interpreted. The implementation strategy of knowledge competition on chemical laboratory safety in colleges and universities is analyzed. It is pointed out education courses about safety should be set up. At the same time，a variety of teaching methods and assessment methods should be used to make the knowledge competition effective. This activity not only can promote the coordinated development of teaching and scientific research，but also can find out the talents suitable for related research about chemical laboratory safety. As a result, it can promote the multi-polar development of talent education. [ABSTRACT FROM AUTHOR]