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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Preventive Medicine is the property of Modern Preventive Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Diagnosis & Therapy on Dermato-venereology is the property of Dermatology Hospital of Southern Medical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To study the intervention effect of emodin on Con A-induced acute liver injury in mice and the underlying mechanism. Methods The male Balb/C mice were randomly divided into the control group, model group, and emodin group. Emodin(25 mg/kg) was administered orally, and Con A(20 mg/kg) was given through intravenous injection at 2 h after emodin administration in the emodin group. In place of emodin, CMC-Na was used in the model group, and mice in the control group were not treated.After 10 h of Con A injection, the blood was collected from the retro-orbital sinus in mice and the serum levels of ALT and AST were measured. Hepatic sections were aseptically obtained for histopathological examination to assess the degree of liver damage. The real-time fluorescent quantitative PCR and Western blotting were employed to evaluate the expression of glucocorticoid-induced tumor necrosis factor receptor(GITR) mRNA and its ligand GITRL mRNA.Results The serum ALT and AST levels in the model group were significantly higher than those in the control group, while those in the emodin group were lower than those in the model group(all P<0.01). Compared with the control group, there were more significant necrosis foci in the liver tissues of the model group, while the liver necrosis was significantly reduced in the emodin group. The relative expression levels of GITR and GITRL mRNA in the model group were higher than those in the control group, while the relative expression levels of GITR and GITRL mRNA in the emodin group were lower than those in the model group(all P<0.05). The relative expression levels of GITR and GITRL protein in the model group were higher than those in the control group, while the relative expression levels of GITR and GITRL protein in the emodin group were lower than those in the model group(all P<0.05). Conclusion Emodin alleviates Con A-induced liver damage by inhibiting GITR/GITRL pathway. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE： To probe into the clinical efficacy of EEG biofeedback combined with paroxetine in treatment of phobia. METHODS： 90 patients with phobia admitted into Hubei Gong‘an County People’s Hospital from Jan. 2014 to Dec. 2015 were selected to be divided into observation group and control group via the random number table, with 45 cases in each. The control group was treated with paroxetine, while the observation group was given EEG biofeedback combined with paroxetine. The efficacy of two groups were observed, the cure time, length of hospital and anxiety and fear factor score and avoidance factor score, Liebowitz social anxiety scale of two groups were compared. RESULTS： The total effective rate of observation group was significantly higher than that of control group; yet the cure time, length of hospital in observation group was significantly shorter than those of control group, with statistical significance (P < 0. 05). After treatment, the anxiety and fear factor score and avoidance factor score, Liebowitz social anxiety scale in observation group were better than those of control group, with statistical significance (P < 0. 05). CONCLUSIONS： The efficacy of EEG biofeedback combined with paroxetine in treatment of phobia is remarkable, which can effectively improve the symptoms of patients and shorten the cure time and length of hospital. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)